{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:06:50Z","timestamp":1793905610930,"version":"4.8.0"},"reference-count":46,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T00:00:00Z","timestamp":1715904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21EB029154"],"award-info":[{"award-number":["R21EB029154"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000070","name":"National Institute of Biomedical Imaging and Bioengineering","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000070","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007161","name":"Boston University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007161","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007229","name":"Harvard University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007229","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Device"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.device.2024.100422","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T14:40:39Z","timestamp":1718376039000},"page":"100422","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ex\u00a0vivo evaluation of a soft optical blood sensor for colonoscopy"],"prefix":"10.1016","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3146-2796","authenticated-orcid":false,"given":"Arincheyan","family":"Gerald","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamin","family":"Palkawong na ayuddhaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max","family":"McCandless","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patra","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnav","family":"Mankad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Addison","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Aihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5490-3155","authenticated-orcid":false,"given":"Sheila","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.device.2024.100422_bib1","first-page":"451","article-title":"Global Cancer Statistics 2022: the trends projection analysis","volume":"10","author":"Chhikara","year":"2023","journal-title":"Chemical Biology Letters"},{"key":"10.1016\/j.device.2024.100422_bib2","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3322\/caac.21772","article-title":"Colorectal cancer statistics, 2023","volume":"73","author":"Siegel","year":"2023","journal-title":"CA A Cancer J. Clin."},{"key":"10.1016\/j.device.2024.100422_bib3","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1001\/jama.2021.4417","article-title":"Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force","volume":"325","author":"Lin","year":"2021","journal-title":"JAMA, J. Am. Med. Assoc."},{"key":"10.1016\/j.device.2024.100422_bib4","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.3390\/diagnostics13071262","article-title":"A Review of Colonoscopy in Intestinal Diseases","volume":"13","author":"Hong","year":"2023","journal-title":"Diagnostics"},{"key":"10.1016\/j.device.2024.100422_bib5","doi-asserted-by":"crossref","first-page":"789","DOI":"10.2214\/ajr.129.5.789","article-title":"Angiodysplasia of the right colon: a cause of gastrointestinal bleeding","volume":"129","author":"Baum","year":"1977","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.device.2024.100422_bib6","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1093\/eurheartj\/ehz964","article-title":"Gastrointestinal bleeding and the risk of colorectal cancer in anticoagulated patients with atrial fibrillation","volume":"43","author":"Rasmussen","year":"2022","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.device.2024.100422_bib7","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000001710","article-title":"New Trends in Acute Management of Colonic Diverticular Bleeding: A Systematic Review","volume":"94","author":"Cirocchi","year":"2015","journal-title":"Medicine"},{"key":"10.1016\/j.device.2024.100422_bib8","article-title":"Inflammatory Bowel Disease Prevalence: Surveillance data from the U.S. National Health and Nutrition Examination Survey","volume":"33","author":"Weisman","year":"2023","journal-title":"Prev. Med. Rep."},{"key":"10.1016\/j.device.2024.100422_bib9","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1053\/j.gastro.2018.12.033","article-title":"Epidemiology, Pathophysiology, and Treatment of Diverticulitis","volume":"156","author":"Strate","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.device.2024.100422_bib10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.5946\/ce.2019.061","article-title":"Endoscopic management of iatrogenic colon perforation","volume":"53","author":"Jung","year":"2020","journal-title":"Clin. Endosc."},{"key":"10.1016\/j.device.2024.100422_bib11","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1136\/flgastro-2019-101266","article-title":"Diagnostic ileocolonoscopy: Getting the basics right","volume":"11","author":"Choy","year":"2020","journal-title":"Frontline Gastroenterol."},{"key":"10.1016\/j.device.2024.100422_bib12","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.cmpb.2013.01.018","article-title":"Haptic feedback and control of a flexible surgical endoscopic robot","volume":"112","author":"Wang","year":"2013","journal-title":"Comput. Methods Progr. Biomed."},{"key":"10.1016\/j.device.2024.100422_bib13","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.3748\/wjg.v22.i5.1811","article-title":"Application of robotics in gastrointestinal endoscopy: A review","volume":"22","author":"Yeung","year":"2016","journal-title":"World J. Gastroenterology"},{"key":"10.1016\/j.device.2024.100422_bib14","first-page":"271","article-title":"3-D multibody modeling of a flexible surgical instrument inside an endoscope","volume":"2","author":"Khatait","year":"2012","journal-title":"ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)"},{"key":"10.1016\/j.device.2024.100422_bib15","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.gie.2019.07.033","article-title":"ASGE review of adverse events in colonoscopy","volume":"90","author":"Kothari","year":"2019","journal-title":"Gastrointest. Endosc."},{"key":"10.1016\/j.device.2024.100422_bib16","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.cgh.2018.08.005","article-title":"Patient, Procedure, and Endoscopist Risk Factors for Perforation, Bleeding, and Splenic Injury After Colonoscopies","volume":"17","author":"Laanani","year":"2019","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.device.2024.100422_bib17","doi-asserted-by":"crossref","first-page":"190","DOI":"10.3748\/wjg.v25.i2.190","article-title":"Adverse events related to colonoscopy: Global trends and future challenges","volume":"25","author":"Kim","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.device.2024.100422_bib18","series-title":"Surgical Treatment: Evidence-Based and Problem-Oriented","article-title":"Management of complications of colonoscopy","author":"Kavic","year":"2001"},{"key":"10.1016\/j.device.2024.100422_bib19","first-page":"468","article-title":"Causes Of Lower Gastrointestinal Bleeding On Colonoscopy","volume":"29","author":"Jehangiri","year":"2017","journal-title":"J.\u00a0Ayub Med. Coll. Abbottabad"},{"key":"10.1016\/j.device.2024.100422_bib20","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1111\/j.1572-0241.2006.00638.x","article-title":"Risk factors for immediate postpolypectomy bleeding of the colon: a multicenter study","volume":"101","author":"Kim","year":"2006","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.device.2024.100422_bib21","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1053\/j.gastro.2005.11.042","article-title":"Lower gastrointestinal bleeding","volume":"130","author":"Rockey","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.device.2024.100422_bib22","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1111\/j.1572-0241.2005.00306.x","article-title":"Urgent colonoscopy for evaluation and management of acute lower gastrointestinal hemorrhage: A randomized controlled trial","volume":"100","author":"Green","year":"2005","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.device.2024.100422_bib23","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1039\/D2AN00283C","article-title":"Microfluidic flow cytometry for blood-based biomarker analysis","volume":"147","author":"Zhang","year":"2022","journal-title":"Analyst"},{"key":"10.1016\/j.device.2024.100422_bib24","doi-asserted-by":"crossref","DOI":"10.1063\/1.4972105","article-title":"Microfluidic cytometers with integrated onchip optical systems for red blood cell and platelet counting","volume":"10","author":"Zhao","year":"2016","journal-title":"Biomicrofluidics"},{"key":"10.1016\/j.device.2024.100422_bib25","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1515\/plm-2012-0042","article-title":"An LED-induced fluorescence detection system with integrated on-chip lens based on microfluidic chips technology\/Ein LED-induziertes Fluoreszenzdetektionssystem mit integrierter \u201cLens-on-Chip\u201d basierend auf der mikrofluidischen Chiptechnologie","volume":"2","author":"Zhao","year":"2013","journal-title":"Photon. Laser Med."},{"key":"10.1016\/j.device.2024.100422_bib26","doi-asserted-by":"crossref","first-page":"R73","DOI":"10.1088\/0967-3334\/26\/3\/R02","article-title":"Microfluidics for flow cytometric analysis of cells and particles","volume":"26","author":"Huh","year":"2005","journal-title":"Physiol. Meas."},{"key":"10.1016\/j.device.2024.100422_bib27","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/jbio.200810018","article-title":"Microfluidics and photonics for Bio-System-on-a-Chip: a review of advancements in technology towards a microfluidic flow cytometry chip","volume":"1","author":"Godin","year":"2008","journal-title":"J.\u00a0Biophot."},{"key":"10.1016\/j.device.2024.100422_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2147\/MDER.S181796","article-title":"Novel optical biosensor method to identify human blood types using free-space frequency-modulated wave of NIR photon technology","volume":"12","author":"Sultan","year":"2019","journal-title":"Med. Devices"},{"key":"10.1016\/j.device.2024.100422_bib29","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.sbsr.2016.01.012","article-title":"Microfluidic chips for forward blood typing performed with a multichannel waveguide-mode sensor","volume":"7","author":"Ashiba","year":"2016","journal-title":"Sensing and Bio-Sensing Research"},{"key":"10.1016\/j.device.2024.100422_bib30","doi-asserted-by":"crossref","DOI":"10.1088\/1742-6596\/1027\/1\/012004","article-title":"Fiber-based optic sensor for detecting human blood clot: Present and future revival","volume":"1027","author":"Elshikeri","year":"2018","journal-title":"J.\u00a0Phys, Conf. Ser."},{"key":"10.1016\/j.device.2024.100422_bib31","doi-asserted-by":"crossref","DOI":"10.1063\/1.4997185","article-title":"A microfluidic approach for hemoglobin detection in whole blood","volume":"7","author":"Taparia","year":"2017","journal-title":"AIP Adv."},{"key":"10.1016\/j.device.2024.100422_bib32","doi-asserted-by":"crossref","DOI":"10.1063\/1.2188847","article-title":"Monitoring of blood sedimentation by a multiplexed light transmission method","volume":"77","author":"Cab-Cauich","year":"2006","journal-title":"Rev. Sci. Instrum."},{"key":"10.1016\/j.device.2024.100422_bib33","series-title":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2020-July","article-title":"Automatic Detection of Intestinal Bleeding using an Optical Sensor for Wireless Capsule Endoscopy","author":"Khan","year":"2020"},{"key":"10.1016\/j.device.2024.100422_bib34","first-page":"88","article-title":"Evidence-Based Guide on Capsule Endoscopy for Small Bowel Bleeding","volume":"13","author":"Pasha","year":"2017","journal-title":"Gastroenterol. Hepatol."},{"key":"10.1016\/j.device.2024.100422_bib35","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.compmedimag.2016.09.005","article-title":"Detection of small colon bleeding in wireless capsule endoscopy videos","volume":"54","author":"Usman","year":"2016","journal-title":"Comput. Med. Imag. Graph."},{"key":"10.1016\/j.device.2024.100422_bib36","doi-asserted-by":"crossref","DOI":"10.1002\/aisy.202270018","article-title":"A Soft Sensor for Bleeding Detection in Colonoscopies","volume":"4","author":"Gerald","year":"2022","journal-title":"Adv. Intell. Syst."},{"key":"10.1016\/j.device.2024.100422_bib37","first-page":"1","article-title":"Measurement of the refractive index of whole blood and its components for a continuous spectral region","volume":"24","author":"Liu","year":"2019","journal-title":"J.\u00a0Biomed. Opt."},{"key":"10.1016\/j.device.2024.100422_bib38","doi-asserted-by":"crossref","first-page":"28","DOI":"10.18178\/ijpmbs.8.2.28-33","article-title":"Numerical Evaluation of the Performance Efficiency of Small-Caliber Colonoscopes in Reducing Patient Pain during a Colonoscopy: Influence of Gender","volume":"8","author":"He","year":"2019","journal-title":"International Journal of Pharma Medicine and Biological Sciences"},{"key":"10.1016\/j.device.2024.100422_bib39","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1177\/0954411912453263","article-title":"Analysis of and mathematical model insight into loop formation in colonoscopy","volume":"226","author":"Cheng","year":"2012","journal-title":"Proc. Inst. Mech. Eng. H"},{"key":"10.1016\/j.device.2024.100422_bib40","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1002\/rcs.61","article-title":"Recording forces exerted on the bowel wall during colonoscopy: in\u00a0vitro evaluation","volume":"1","author":"Dogramadzi","year":"2005","journal-title":"Int. J. Med. Robot."},{"key":"10.1016\/j.device.2024.100422_bib41","series-title":"NASA Task Load Index (TLX). Tech. Rep. Moffett Field, California, United States: Human Performance Research Group","author":"Hart","year":"1986"},{"key":"10.1016\/j.device.2024.100422_bib42","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1572-0241.2006.01002.x","article-title":"Computer-assisted colonoscopy (the NeoGuide Endoscopy System): Results of the first human clinical trial (\"PACE Study\")","volume":"102","author":"Eickhoff","year":"2007","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.device.2024.100422_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2022.110747","article-title":"Conformable and robust microfluidic force sensors to enable precision joint replacement surgery","volume":"219","author":"Ives","year":"2022","journal-title":"Mater. Des."},{"key":"10.1016\/j.device.2024.100422_bib44","article-title":"Multiscale characterization of the mechanical behavior of a printed circuit board (PCB)","volume":"34","author":"Atintoh","year":"2023","journal-title":"Mater. Today Commun."},{"key":"10.1016\/j.device.2024.100422_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.hybadv.2023.100090","article-title":"Bending analysis of glass fiber reinforced epoxy composites\/copper-clad laminates for multilayer printed circuit boards","volume":"4","author":"Islam","year":"2023","journal-title":"Hybrid Advances"},{"key":"10.1016\/j.device.2024.100422_bib46","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.3390\/s19051057","article-title":"PDMS microlenses for focusing light in narrow band imaging diagnostics","volume":"19","author":"Costa","year":"2019","journal-title":"Sensors"}],"container-title":["Device"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666998624002655?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666998624002655?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T15:15:12Z","timestamp":1726845312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666998624002655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":46,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S2666998624002655"],"URL":"https:\/\/doi.org\/10.1016\/j.device.2024.100422","relation":{},"ISSN":["2666-9986"],"issn-type":[{"value":"2666-9986","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ex\u00a0vivo evaluation of a soft optical blood sensor for colonoscopy","name":"articletitle","label":"Article Title"},{"value":"Device","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.device.2024.100422","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"100422"}}