{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T05:25:20Z","timestamp":1794029120422,"version":"4.8.0"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","award":["18CDA34110070"],"award-info":[{"award-number":["18CDA34110070"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000135","name":"National Institutes of Health Blueprint for Neuroscience Research","doi-asserted-by":"publisher","award":["R01HD079642"],"award-info":[{"award-number":["R01HD079642"]}],"id":[{"id":"10.13039\/100000135","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Disability and Health Journal"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.dhjo.2026.102126","type":"journal-article","created":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:08:31Z","timestamp":1784246911000},"page":"102126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of weight loss on cardiovascular function in adolescents and young adults with overweight\/ obesity and intellectual and developmental disabilities"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1250-4199","authenticated-orcid":false,"given":"Geetha","family":"Haligheri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Kathol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Kuzava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Goth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"White","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent S.","family":"Staggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Donnelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren T.","family":"Ptomey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Forsha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.dhjo.2026.102126_bib1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s11892-018-1062-9","article-title":"The impact of childhood and adolescent obesity on cardiovascular risk in adulthood: a systematic review","volume":"18","author":"Sommer","year":"2018","journal-title":"Curr Diabetes Rep"},{"issue":"1","key":"10.1016\/j.dhjo.2026.102126_bib2","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/ijo.2009.61","article-title":"Childhood obesity and adult cardiovascular disease risk: a systematic review","volume":"34","author":"Dunford","year":"2010","journal-title":"Int J Obes"},{"issue":"11","key":"10.1016\/j.dhjo.2026.102126_bib3","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1111\/j.1467-789X.2012.01015.x","article-title":"The impact of childhood obesity on morbidity and mortality in adulthood: a systematic review","volume":"13","author":"Park","year":"2012","journal-title":"Obes Rev"},{"issue":"43","key":"10.1016\/j.dhjo.2026.102126_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta19430","article-title":"The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis","volume":"19","author":"Simmonds","year":"2015","journal-title":"Health Technol Assess"},{"issue":"23","key":"10.1016\/j.dhjo.2026.102126_bib5","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1056\/NEJMoa072515","article-title":"Childhood body-mass index and the risk of coronary heart disease in adulthood","volume":"357","author":"Baker","year":"2007","journal-title":"N Engl J Med"},{"issue":"8","key":"10.1016\/j.dhjo.2026.102126_bib6","doi-asserted-by":"crossref","DOI":"10.1038\/nutd.2016.34","article-title":"Association between impaired fasting glycaemia in pediatric obesity and type 2 diabetes in young adulthood","volume":"6","author":"Hagman","year":"2016","journal-title":"Nutr Diabetes"},{"issue":"9727","key":"10.1016\/j.dhjo.2026.102126_bib7","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1016\/S0140-6736(10)60171-7","article-title":"Childhood obesity","volume":"375","author":"Han","year":"2010","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.dhjo.2026.102126_bib8","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/dmcn.12868","article-title":"Morbidity and medication in a large population of individuals with Down syndrome compared to the general population","volume":"58","author":"Alexander","year":"2016","journal-title":"Dev Med Child Neurol"},{"issue":"5 Suppl","key":"10.1016\/j.dhjo.2026.102126_bib9","doi-asserted-by":"crossref","first-page":"1307S","DOI":"10.1093\/ajcn\/72.5.1307s","article-title":"Origin of atherosclerosis in childhood and adolescence","volume":"72","author":"McGill","year":"2000","journal-title":"Am J Clin Nutr"},{"issue":"8","key":"10.1016\/j.dhjo.2026.102126_bib10","doi-asserted-by":"crossref","first-page":"1998","DOI":"10.1161\/01.ATV.20.8.1998","article-title":"Associations of coronary heart disease risk factors with the intermediate lesion of atherosclerosis in youth. The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) research group","volume":"20","author":"McGill","year":"2000","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"4","key":"10.1016\/j.dhjo.2026.102126_bib11","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1161\/01.CIR.102.4.374","article-title":"Association of coronary heart disease risk factors with microscopic qualities of coronary atherosclerosis in youth","volume":"102","author":"McGill","year":"2000","journal-title":"Circulation"},{"issue":"12","key":"10.1016\/j.dhjo.2026.102126_bib12","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.jcmg.2014.08.006","article-title":"Childhood obesity: impact on cardiac geometry and function","volume":"7","author":"Mangner","year":"2014","journal-title":"JACC, Cardiovasc Imaging"},{"issue":"5","key":"10.1016\/j.dhjo.2026.102126_bib13","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1007\/s00431-022-04384-0","article-title":"Relationship between overweight and obesity and cardiac dimensions and function in a paediatric population","volume":"181","author":"Cabeza","year":"2022","journal-title":"Eur J Pediatr"},{"issue":"7","key":"10.1016\/j.dhjo.2026.102126_bib14","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1515\/jpem-2020-0597","article-title":"Investigation of the prevalence of cardiovascular risk factors in obese patients diagnosed with metabolic syndrome in childhood and examination of left ventricular function by echocardiography","volume":"34","author":"Ozden","year":"2021","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"12","key":"10.1016\/j.dhjo.2026.102126_bib15","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1016\/j.amjcard.2004.03.016","article-title":"Comparison of myocardial function in children with body mass indexes >\/=25 versus those <25 kg\/m2","volume":"93","author":"Mehta","year":"2004","journal-title":"Am J Cardiol"},{"issue":"7","key":"10.1016\/j.dhjo.2026.102126_bib16","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1177\/00099228231201203","article-title":"Childhood obesity is associated with subclinical left ventricular dysfunction detected by speckle tracking echocardiography","volume":"63","author":"Dehghan","year":"2024","journal-title":"Clin Pediatr (Phila)"},{"issue":"1","key":"10.1016\/j.dhjo.2026.102126_bib17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.5152\/balkanmedj.2015.15136","article-title":"Effect of obesity on left ventricular longitudinal myocardial strain by speckle tracking echocardiography in children and adolescents","volume":"32","author":"Kibar","year":"2015","journal-title":"Balkan Med J"},{"issue":"3","key":"10.1016\/j.dhjo.2026.102126_bib18","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jacc.2014.10.044","article-title":"Exercise limitation associated with asymptomatic left ventricular impairment: analogy with stage B heart failure","volume":"65","author":"Kosmala","year":"2015","journal-title":"J Am Coll Cardiol"},{"issue":"12","key":"10.1016\/j.dhjo.2026.102126_bib19","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/j.jcmg.2014.09.006","article-title":"Linking pediatric obesity to subclinical alterations in cardiac structure and function","volume":"7","author":"Zachariah","year":"2014","journal-title":"JACC, Cardiovasc Imaging"},{"issue":"6","key":"10.1016\/j.dhjo.2026.102126_bib20","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1253\/circj.CJ-18-1245","article-title":"In-Depth insight into the mechanisms of cardiac dysfunction in patients with type 1 diabetes mellitus using layer-specific strain analysis","volume":"83","author":"Iso","year":"2019","journal-title":"Circ J"},{"issue":"25 Pt A","key":"10.1016\/j.dhjo.2026.102126_bib21","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1016\/j.jacc.2014.01.073","article-title":"Use of myocardial strain imaging by echocardiography for the early detection of cardiotoxicity in patients during and after cancer chemotherapy: a systematic review","volume":"63","author":"Thavendiranathan","year":"2014","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.dhjo.2026.102126_bib24","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/joim.12741","article-title":"BMI change during puberty and the risk of heart failure","volume":"283","author":"Kindblom","year":"2018","journal-title":"J Intern Med"},{"issue":"24","key":"10.1016\/j.dhjo.2026.102126_bib25","first-page":"1926","article-title":"Body weight in adolescence and long-term risk of early heart failure in adulthood among men in Sweden","volume":"38","author":"Rosengren","year":"2017","journal-title":"Eur Heart J"},{"issue":"2","key":"10.1016\/j.dhjo.2026.102126_bib26","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1161\/CIRCULATIONAHA.118.039132","article-title":"Higher body mass index in adolescence predicts cardiomyopathy risk in midlife","volume":"140","author":"Robertson","year":"2019","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.dhjo.2026.102126_bib22","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1161\/CIRCULATIONAHA.105.548206","article-title":"Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age","volume":"113","author":"Lloyd-Jones","year":"2006","journal-title":"Circulation"},{"issue":"10","key":"10.1016\/j.dhjo.2026.102126_bib23","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1002\/oby.20495","article-title":"Impact of diet and exercise training-induced weight loss on myocardial mechanics in severely obese adolescents","volume":"21","author":"Obert","year":"2013","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.dhjo.2026.102126_bib27","article-title":"Relationship between obesity and intellectual\/developmental disability in an Ohio telepsychiatry clinic: a retrospective review","author":"Shameem","year":"2024","journal-title":"J Autism Dev Disord"},{"issue":"9","key":"10.1016\/j.dhjo.2026.102126_bib28","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1111\/jir.12767","article-title":"Weight status and associated comorbidities in children and adults with Down syndrome, autism spectrum disorder and intellectual and developmental disabilities","volume":"64","author":"Ptomey","year":"2020","journal-title":"J Intellect Disabil Res"},{"issue":"16","key":"10.1016\/j.dhjo.2026.102126_bib29","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1001\/jama.2018.3060","article-title":"Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016","volume":"319","author":"Hales","year":"2018","journal-title":"JAMA"},{"issue":"9","key":"10.1016\/j.dhjo.2026.102126_bib30","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1111\/jir.12090","article-title":"Overweight and obesity in youth with developmental disabilities: a call to action","volume":"58","author":"Grondhuis","year":"2014","journal-title":"J Intellect Disabil Res"},{"issue":"9","key":"10.1016\/j.dhjo.2026.102126_bib31","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1017\/S1047951122003158","article-title":"Early cardiac dysfunction in obese adolescents with Down syndrome or autism","volume":"33","author":"Haligheri","year":"2023","journal-title":"Cardiol Young"},{"issue":"3","key":"10.1016\/j.dhjo.2026.102126_bib32","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2021-050261","article-title":"Weight loss interventions for adolescents with intellectual disabilities: an RCT","volume":"148","author":"Ptomey","year":"2021","journal-title":"Pediatrics"},{"key":"10.1016\/j.dhjo.2026.102126_bib33","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cct.2016.10.009","article-title":"Weight management for adolescents with intellectual and developmental disabilities: rationale and design for an 18 month randomized trial","volume":"51","author":"Donnelly","year":"2016","journal-title":"Contemp Clin Trials"},{"key":"10.1016\/j.dhjo.2026.102126_bib34","series-title":"The Stoplight Diet for Children: An Eight-Week Program for Parents and Children","author":"Epstein","year":"1988"},{"key":"10.1016\/j.dhjo.2026.102126_bib35","series-title":"U.S. Department of Agriculture. Choose Myplate","year":"2013"},{"key":"10.1016\/j.dhjo.2026.102126_bib36","article-title":"2010, to the secretary of agriculture and the secretary of health and human services","year":"2010","journal-title":"Agricultural Research Service"},{"key":"10.1016\/j.dhjo.2026.102126_bib37","series-title":"Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients)","year":"2002"},{"issue":"6","key":"10.1016\/j.dhjo.2026.102126_bib38","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1080\/03014460.2020.1808065","article-title":"A method for calculating BMI z-scores and percentiles above the 95(th) percentile of the CDC growth charts","volume":"47","author":"Wei","year":"2020","journal-title":"Ann Hum Biol"},{"issue":"Suppl 4","key":"10.1016\/j.dhjo.2026.102126_bib39","doi-asserted-by":"crossref","first-page":"S164","DOI":"10.1542\/peds.2007-2329C","article-title":"Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report","volume":"120","author":"Barlow","year":"2007","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.dhjo.2026.102126_bib40","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-0541","article-title":"Body composition and BMI growth charts in children with Down syndrome","volume":"138","author":"Hatch-Stein","year":"2016","journal-title":"Pediatrics"},{"issue":"4 Suppl Growth Standard","key":"10.1016\/j.dhjo.2026.102126_bib41","doi-asserted-by":"crossref","first-page":"S314","DOI":"10.1177\/15648265060274S512","article-title":"Body composition assessment for development of an international growth standard for preadolescent and adolescent children","volume":"27","author":"Lohman","year":"2006","journal-title":"Food Nutr Bull"},{"issue":"5","key":"10.1016\/j.dhjo.2026.102126_bib42","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.echo.2010.03.019","article-title":"Recommendations for quantification methods during the performance of a pediatric echocardiogram: a report from the pediatric measurements writing group of the American society of echocardiography pediatric and congenital heart disease council","volume":"23","author":"Lopez","year":"2010","journal-title":"J Am Soc Echocardiogr"},{"issue":"5","key":"10.1016\/j.dhjo.2026.102126_bib43","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/0735-1097(92)90385-Z","article-title":"Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight","volume":"20","author":"de Simone","year":"1992","journal-title":"J Am Coll Cardiol"},{"issue":"10","key":"10.1016\/j.dhjo.2026.102126_bib44","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.amjhyper.2005.05.027","article-title":"Different normalizations for body size and population attributable risk of left ventricular hypertrophy: the MAVI study","volume":"18","author":"de Simone","year":"2005","journal-title":"Am J Hypertens"},{"issue":"2","key":"10.1016\/j.dhjo.2026.102126_bib45","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0735-1097(97)88335-0","article-title":"Assessment of mitral annulus velocity by doppler tissue imaging in the evaluation of left ventricular diastolic function","volume":"30","author":"Sohn","year":"1997","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.dhjo.2026.102126_bib46","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s12471-012-0254-1","article-title":"Adults with Down syndrome have reduced cardiac response after light exercise testing","volume":"20","author":"Vis","year":"2012","journal-title":"Neth Heart J"},{"issue":"3","key":"10.1016\/j.dhjo.2026.102126_bib47","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.echo.2011.01.015","article-title":"Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE\/EAE consensus statement on methodology and indications endorsed by the Japanese society of echocardiography","volume":"24","author":"Mor-Avi","year":"2011","journal-title":"J Am Soc Echocardiogr"},{"issue":"8","key":"10.1016\/j.dhjo.2026.102126_bib48","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1097\/HJH.0000000000002081","article-title":"Current assessment of pulse wave velocity: comprehensive review of validation studies","volume":"37","author":"Milan","year":"2019","journal-title":"J Hypertens"},{"issue":"6","key":"10.1016\/j.dhjo.2026.102126_bib49","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1093\/ajh\/hpt243","article-title":"Validation of oscillometric pulse wave analysis measurements in children","volume":"27","author":"Stoner","year":"2014","journal-title":"Am J Hypertens"},{"issue":"5","key":"10.1016\/j.dhjo.2026.102126_bib50","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1161\/HYPERTENSIONAHA.109.192639","article-title":"Noninvasive assessment of subclinical atherosclerosis in children and adolescents: recommendations for standard assessment for clinical research: a scientific statement from the American Heart Association","volume":"54","author":"Urbina","year":"2009","journal-title":"Hypertension"},{"key":"10.1016\/j.dhjo.2026.102126_bib51","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jpeds.2019.04.059","article-title":"Cross-sectional study of arterial stiffness in adolescents with Down syndrome","volume":"212","author":"Kelly","year":"2019","journal-title":"J Pediatr"},{"issue":"12","key":"10.1016\/j.dhjo.2026.102126_bib52","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1111\/jir.12894","article-title":"Training responsiveness of cardiorespiratory fitness and arterial stiffness following moderate-intensity continuous training and high-intensity interval training in adults with intellectual and developmental disabilities","volume":"65","author":"Melo","year":"2021","journal-title":"J Intellect Disabil Res"},{"issue":"3","key":"10.1016\/j.dhjo.2026.102126_bib53","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2017-1904","article-title":"Clinical practice guideline for screening and management of high blood pressure in children and adolescents","volume":"140","author":"Flynn","year":"2017","journal-title":"Pediatrics"},{"issue":"10","key":"10.1016\/j.dhjo.2026.102126_bib54","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1249\/MSS.0000000000000657","article-title":"Validity and reproducibility of a new treadmill protocol: the fitkids treadmill test","volume":"47","author":"Kotte","year":"2015","journal-title":"Med Sci Sports Exerc"},{"issue":"8","key":"10.1016\/j.dhjo.2026.102126_bib55","doi-asserted-by":"crossref","first-page":"538","DOI":"10.2459\/JCM.0000000000000261","article-title":"Childhood obesity and cardiac remodeling: from cardiac structure to myocardial mechanics","volume":"16","author":"Tadic","year":"2015","journal-title":"J Cardiovasc Med (Hagerstown)"},{"issue":"4","key":"10.1016\/j.dhjo.2026.102126_bib56","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.echo.2011.12.018","article-title":"Interaction between myocardial and vascular changes in obese children: a pilot study","volume":"25","author":"Koopman","year":"2012","journal-title":"J Am Soc Echocardiogr"},{"issue":"8","key":"10.1016\/j.dhjo.2026.102126_bib57","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1111\/j.1540-8175.2007.00484.x","article-title":"Effect of obesity on left ventricular structure and myocardial systolic function: assessment by tissue doppler imaging and strain\/strain rate imaging","volume":"24","author":"Tumuklu","year":"2007","journal-title":"Echocardiography"},{"issue":"25","key":"10.1016\/j.dhjo.2026.102126_bib58","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1016\/j.jacc.2009.08.030","article-title":"Physical activity reduces systemic blood pressure and improves early markers of atherosclerosis in pre-pubertal obese children","volume":"54","author":"Farpour-Lambert","year":"2009","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.dhjo.2026.102126_bib59","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.pcad.2018.01.012","article-title":"Effect of high intensity interval training on cardiac function in children with obesity: a randomised controlled trial","volume":"61","author":"Ingul","year":"2018","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.dhjo.2026.102126_bib60","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2147\/DMSO.S124541","article-title":"Improvement of impaired diastolic left ventricular function after diet-induced weight reduction in severe obesity","volume":"10","author":"Karimian","year":"2017","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"2","key":"10.1016\/j.dhjo.2026.102126_bib61","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s11695-015-1748-x","article-title":"Weight loss with sleeve gastrectomy in Obese type 2 diabetes mellitus: impact on cardiac function","volume":"26","author":"Leung","year":"2016","journal-title":"Obes Surg"},{"issue":"4","key":"10.1016\/j.dhjo.2026.102126_bib62","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/00000441-200104000-00003","article-title":"Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome","volume":"321","author":"Alpert","year":"2001","journal-title":"Am J Med Sci"},{"issue":"22","key":"10.1016\/j.dhjo.2026.102126_bib63","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1093\/eurheartj\/ehl163","article-title":"Abnormal myocardial deformation properties in obese, non-hypertensive children: an ambulatory blood pressure monitoring, standard echocardiographic, and strain rate imaging study","volume":"27","author":"Di Salvo","year":"2006","journal-title":"Eur Heart J"},{"issue":"4","key":"10.1016\/j.dhjo.2026.102126_bib64","first-page":"206","article-title":"[Left ventricular mass and systolic-diastolic function of the heart in children and adolescents with hypertension and hypertension accompanying obesity]","volume":"62","author":"Baszun-Stepaniuk","year":"2005","journal-title":"Przegl Lek"},{"issue":"7","key":"10.1016\/j.dhjo.2026.102126_bib65","first-page":"503","article-title":"[Obesity and cardiovascular diseases-theoretical background and therapeutic consequences]","volume":"93","author":"Voller","year":"2004","journal-title":"Z Kardiol"},{"key":"10.1016\/j.dhjo.2026.102126_bib66","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1475-2891-7-25","article-title":"Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: a randomised controlled weight loss trial","volume":"7","author":"Truby","year":"2008","journal-title":"Nutr J"},{"issue":"1","key":"10.1016\/j.dhjo.2026.102126_bib67","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s40119-021-00251-5","article-title":"Pulmonary hypertension in the population with Down syndrome","volume":"11","author":"Bush","year":"2022","journal-title":"Cardiol Ther"},{"issue":"5","key":"10.1016\/j.dhjo.2026.102126_bib68","article-title":"Hypothyroidism in patients with Down syndrome: Prevalence and association with congenital heart defects","volume":"11","author":"Gorini","year":"2024","journal-title":"Children (Basel)"},{"issue":"3","key":"10.1016\/j.dhjo.2026.102126_bib69","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.archger.2006.01.003","article-title":"Does Down's syndrome support the homocysteine theory of atherogenesis? Experience in elderly subjects with trisomy 21","volume":"43","author":"Licastro","year":"2006","journal-title":"Arch Gerontol Geriatr"}],"container-title":["Disability and Health Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936657426001032?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1936657426001032?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T04:53:24Z","timestamp":1794027204000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1936657426001032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":69,"alternative-id":["S1936657426001032"],"URL":"https:\/\/doi.org\/10.1016\/j.dhjo.2026.102126","relation":{},"ISSN":["1936-6574"],"issn-type":[{"value":"1936-6574","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of weight loss on cardiovascular function in adolescents and young adults with overweight\/ obesity and intellectual and developmental disabilities","name":"articletitle","label":"Article Title"},{"value":"Disability and Health Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dhjo.2026.102126","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102126"}}