{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:08:57Z","timestamp":1777417737162,"version":"3.51.4"},"reference-count":54,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,4,1]],"date-time":"2010-04-01T00:00:00Z","timestamp":1270080000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetes & Metabolism"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1016\/j.diabet.2010.01.001","type":"journal-article","created":{"date-parts":[[2010,2,27]],"date-time":"2010-02-27T09:41:43Z","timestamp":1267263703000},"page":"91-96","source":"Crossref","is-referenced-by-count":29,"title":["It is not yet the time to stop screening diabetic patients for silent myocardial ischaemia"],"prefix":"10.1016","volume":"36","author":[{"given":"P.","family":"Valensi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Cosson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabet.2010.01.001_bib1","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1016\/S0735-1097(02)02065-X","article-title":"Coronary atherosclerosis in diabetes mellitus: a population-based autopsy study","volume":"40","author":"Goraya","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.diabet.2010.01.001_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S1262-3636(07)70060-5","article-title":"Are silent coronary stenoses predictable in diabetic patients and predictive of cardiovascular events?","volume":"29","author":"Cosson","year":"2003","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diabet.2010.01.001_bib3","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.2337\/diacare.26.4.1313","article-title":"Prognosis for coronary stenoses in patients with diabetes and silent myocardial ischemia","volume":"26","author":"Cosson","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2010.01.001_bib4","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.2337\/diacare.28.11.2722","article-title":"Predictive value of silent myocardial ischemia for cardiac events in diabetic patients: influence of age in a French multicenter study","volume":"28","author":"Valensi","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2010.01.001_bib5","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.2337\/dc07-9927","article-title":"Screening for coronary artery disease in patients with diabetes","volume":"30","author":"Bax","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2010.01.001_bib6","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1016\/S1262-3636(04)72800-1","article-title":"Identification of myocardial ischemia in the diabetic patient Joint ALFEDIAM and SFC recommendations","volume":"30","author":"Puel","year":"2004","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diabet.2010.01.001_bib7","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.jacc.2006.04.077","article-title":"The potential of myocardial perfusion scintigraphy for risk stratification of asymptomatic patients with type 2 diabetes","volume":"48","author":"Bax","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.diabet.2010.01.001_bib8","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1016\/j.jacc.2007.01.079","article-title":"Noninvasive screening for coronary atherosclerosis and silent ischemia in asymptomatic type 2 diabetic patients: is it appropriate and cost-effective?","volume":"49","author":"Beller","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.diabet.2010.01.001_bib9","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.jacc.2006.04.076","article-title":"Screening asymptomatic diabetic patients for coronary artery disease: why not?","volume":"48","author":"Miller","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.diabet.2010.01.001_bib10","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1001\/jama.2009.476","article-title":"Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial","volume":"301","author":"Young","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.diabet.2010.01.001_bib11","doi-asserted-by":"crossref","first-page":"2503","DOI":"10.1056\/NEJMoa0805796","article-title":"A randomized trial of therapies for type 2 diabetes and coronary artery disease","volume":"360","author":"Frye","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib12","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1056\/NEJMoa070829","article-title":"Optimal medical therapy with or without PCI for stable coronary disease","volume":"356","author":"Boden","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib13","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1161\/CIRCULATIONAHA.108.829176","article-title":"Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005","volume":"119","author":"Preis","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib14","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/S0140-6736(03)13636-7","article-title":"MRC\/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial","volume":"361","author":"Collins","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.diabet.2010.01.001_bib15","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1016\/S0140-6736(05)67667-2","article-title":"Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial","volume":"366","author":"Keech","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.diabet.2010.01.001_bib16","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1056\/NEJMoa0802987","article-title":"Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes","volume":"358","author":"Patel","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib17","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1056\/NEJMoa0706245","article-title":"Effect of a multifactorial intervention on mortality in type 2 diabetes","volume":"358","author":"Gaede","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib18","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1007\/s00125-004-1438-z","article-title":"Risk factor management in diabetic and non-diabetic patients with coronary heart disease Findings from the EUROASPIRE I AND II surveys","volume":"47","author":"Pyorala","year":"2004","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabet.2010.01.001_bib19","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1056\/NEJMoa0802743","article-title":"Effects of intensive glucose lowering in type 2 diabetes","volume":"358","author":"Gerstein","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib20","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1056\/NEJMoa0808431","article-title":"Glucose control and vascular complications in veterans with type 2 diabetes","volume":"360","author":"Duckworth","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib21","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1042\/CS20000335","article-title":"The UKPDS risk engine: a model for the risk of coronary heart disease in type II diabetes (UKPDS 56)","volume":"101","author":"Stevens","year":"2001","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.diabet.2010.01.001_bib22","doi-asserted-by":"crossref","unstructured":"Cosson E, Chanu B, Nguyen MT, Balta C, Balta S, Paries J, et al. Valeur diagnostique et pronostique du score de l\u2019UKPDS, des recommandations am\u00e9ricaines et fran\u00e7aises dans le cadre de la recherche d\u2019une isch\u00e9mie myocardique silencieuse. Diabetes Metab 2009;35:O23 [abstract].","DOI":"10.1016\/S1262-3636(09)71715-X"},{"key":"10.1016\/j.diabet.2010.01.001_bib23","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1161\/01.STR.27.11.2033","article-title":"Proteinuria predicts stroke and other atherosclerotic vascular disease events in non diabetic and non-insulin-dependent diabetic subjects","volume":"27","author":"Miettinen","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.diabet.2010.01.001_bib24","doi-asserted-by":"crossref","unstructured":"Cosson E, Nguyen MT, Balta C, Paries J,Valensi P. Int\u00e9r\u00eat des recommandations Alfediam-SFC (RECO) s\u00e9lectionnant les diab\u00e9tiques \u00e0 risque d\u2019isch\u00e9mie myocardique silencieuse (IMS). Une \u00e9tude de suivi avec analyse des changements de pratique depuis 1992. Diabetes Metab 2008;34:O54 [abstract].","DOI":"10.1016\/S1262-3636(08)72864-7"},{"key":"10.1016\/j.diabet.2010.01.001_bib25","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1001\/jama.292.12.1462","article-title":"Global risk scores and exercise testing for predicting all-cause mortality in a preventive medicine program","volume":"292","author":"Aktas","year":"2004","journal-title":"JAMA"},{"key":"10.1016\/j.diabet.2010.01.001_bib26","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1161\/01.CIR.0000143226.40607.71","article-title":"Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic persons as a function of the Framingham risk score","volume":"110","author":"Balady","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib27","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1056\/NEJMoa043012","article-title":"Heart-rate profile during exercise as a predictor of sudden death","volume":"352","author":"Jouven","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib28","doi-asserted-by":"crossref","first-page":"552","DOI":"10.7326\/0003-4819-132-7-200004040-00007","article-title":"Heart rate recovery after submaximal exercise testing as a predictor of mortality in a cardiovascularly healthy cohort","volume":"132","author":"Cole","year":"2000","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib29","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1161\/CIRCULATIONAHA.105.166543","article-title":"Exercise testing in asymptomatic adults: a statement for professionals from the American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise. Cardiac Rehabilitation, and Prevention","volume":"112","author":"Lauer","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib30","first-page":"159","article-title":"Comment je traite et prends en charge une isch\u00e9mie myocardique silencieuse. Le point de vue du diab\u00e9tologue","author":"Valensi","year":"2006","journal-title":"J Annu Diabetol H\u00f4tel Dieu"},{"key":"10.1016\/j.diabet.2010.01.001_bib31","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1056\/NEJMoa050461","article-title":"Intensive lipid lowering with atorvastatin in patients with stable coronary disease","volume":"352","author":"LaRosa","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib32","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1161\/01.CIR.90.2.762","article-title":"Effects of treatment on outcome in mildly symptomatic patients with ischemia during daily life. The Atenolol Silent Ischemia Study (ASIST)","volume":"90","author":"Pepine","year":"1994","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib33","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1161\/01.CIR.95.8.2037","article-title":"Asymptomatic Cardiac Ischemia Pilot (ACIP) study two-year follow-up: outcomes of patients randomized to initial strategies of medical therapy versus revascularization","volume":"95","author":"Davies","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib34","doi-asserted-by":"crossref","DOI":"10.1016\/j.ahj.2004.07.027","article-title":"Risk reduction of cardiac events by screening of unknown asymptomatic coronary artery disease in subjects with type 2 diabetes mellitus at high cardiovascular risk: an open-label randomized pilot study","volume":"149","author":"Faglia","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.diabet.2010.01.001_bib35","doi-asserted-by":"crossref","first-page":"I311","DOI":"10.1161\/CIRCULATIONAHA.104.525022","article-title":"Improved survival in asymptomatic diabetic patients with high-risk SPECT imaging treated with coronary artery bypass grafting","volume":"112","author":"Sorajja","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib36","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.1161\/01.CIR.85.6.2100","article-title":"Early mortality of acute myocardial infarction in patients with and without prior coronary revascularization surgery. A Coronary Artery Surgery Study Registry Study","volume":"85","author":"Davis","year":"1992","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib37","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/S0735-1097(01)01571-6","volume":"38","author":"Berger","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.diabet.2010.01.001_bib38","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1161\/CIRCULATIONAHA.107.743963","article-title":"Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy","volume":"117","author":"Shaw","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib39","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1056\/NEJMoa072771","article-title":"Effect of PCI on quality of life in patients with stable coronary disease","volume":"359","author":"Weintraub","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2010.01.001_bib40","doi-asserted-by":"crossref","unstructured":"Garg P, Normand SL, Silbaugh TS, Wolf RE, Zelevinsky K, Lovett A, et al. Drug-eluting or bare-metal stenting in patients with diabetes mellitus: results from the Massachusetts Data Analysis Center Registry. Circulation 2008;118:2277\u201385 [7p following 85].","DOI":"10.1161\/CIRCULATIONAHA.108.820159"},{"key":"10.1016\/j.diabet.2010.01.001_bib41","doi-asserted-by":"crossref","first-page":"a1331","DOI":"10.1136\/bmj.a1331","article-title":"Drug eluting and bare metal stents in people with and without diabetes: collaborative network meta-analysis","volume":"337","author":"Stettler","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.diabet.2010.01.001_bib42","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.ahj.2007.10.012","article-title":"Design of the Future Revascularization Evaluation in patients with Diabetes mellitus: Optimal management of Multivessel disease (FREEDOM) Trial","volume":"155","author":"Farkouh","year":"2008","journal-title":"Am Heart J"},{"key":"10.1016\/j.diabet.2010.01.001_bib43","doi-asserted-by":"crossref","first-page":"13S","DOI":"10.1016\/0895-7061(95)00028-N","article-title":"Impairment of flow-dependent coronary dilation in hypertensive patients. Demonstration by cold pressor test induced flow velocity increase","volume":"8","author":"Nitenberg","year":"1995","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.diabet.2010.01.001_bib44","doi-asserted-by":"crossref","first-page":"813","DOI":"10.2337\/diabetes.51.3.813","article-title":"Coronary microvascular adaptation to myocardial metabolic demand can be restored by inhibition of iron-catalyzed formation of oxygen free radicals in type 2 diabetic patients","volume":"51","author":"Nitenberg","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.diabet.2010.01.001_bib45","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.2337\/diabetes.50.5.1180","article-title":"Impairment of coronary microvascular dilation in response to cold pressor-induced sympathetic stimulation in type 2 diabetic patients with abnormal stress thallium imaging","volume":"50","author":"Nitenberg","year":"2001","journal-title":"Diabetes"},{"key":"10.1016\/j.diabet.2010.01.001_bib46","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1161\/01.CIR.97.8.736","article-title":"Coronary artery responses to physiological stimuli are improved by deferoxamine but not by L-arginine in non-insulin-dependent diabetic patients with angiographically normal coronary arteries and no other risk factors","volume":"97","author":"Nitenberg","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.diabet.2010.01.001_bib47","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.atherosclerosis.2005.02.030","article-title":"Cardiovascular outcome of patients with abnormal coronary vasomotion and normal coronary arteriography is worse in type 2 diabetes mellitus than in arterial hypertension: a 10 year follow-up study","volume":"183","author":"Nitenberg","year":"2005","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.diabet.2010.01.001_bib48","first-page":"128","article-title":"Determinants of echocardiographically measured left ventricular mass in diabetic patients with or without silent myocardial ischaemia","volume":"25","author":"Sachs","year":"1999","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diabet.2010.01.001_bib49","doi-asserted-by":"crossref","unstructured":"Greenland P, Bonow RO, Brundage BH, Budoff MJ, Eisenberg MJ, Grundy SM, et al. ACCF\/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF\/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography). Circulation 2007;115:402\u201326.","DOI":"10.1161\/CIRCULATIONAHA..107.181425"},{"key":"10.1016\/j.diabet.2010.01.001_bib50","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.2337\/diacare.28.11.2787","article-title":"Ischemia imaging and plaque imaging in diabetes: complementary tools to improve cardiovascular risk management","volume":"28","author":"Raggi","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2010.01.001_bib51","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.2337\/dc07-0992","article-title":"Osteoprotegerin: a novel independent marker for silent myocardial ischemia in asymptomatic diabetic patients","volume":"30","author":"Avignon","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2010.01.001_bib52","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.2337\/diacare.22.12.2044","article-title":"Soluble L-selectin level is a marker for coronary artery disease in type 2 diabetic patients","volume":"22","author":"Albertini","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2010.01.001_bib53","doi-asserted-by":"crossref","unstructured":"Cosson E, Nguyen M, Pham I, Pontet M, Nitenberg A,Valensi P. N-terminal pro-B-type natriuretic peptide: an independent marker for coronary artery disease in asymptomatic diabetic patients Diabet Med 2009;26:872\u20139.","DOI":"10.1111\/j.1464-5491.2009.02788.x"},{"key":"10.1016\/j.diabet.2010.01.001_bib54","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/0735-1097(95)00327-4","article-title":"Close relation of endothelial function in the human coronary and peripheral circulations","volume":"26","author":"Anderson","year":"1995","journal-title":"J Am Coll Cardiol"}],"container-title":["Diabetes & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1262363610000285?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1262363610000285?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T04:33:12Z","timestamp":1635049992000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1262363610000285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["S1262363610000285"],"URL":"https:\/\/doi.org\/10.1016\/j.diabet.2010.01.001","relation":{},"ISSN":["1262-3636"],"issn-type":[{"value":"1262-3636","type":"print"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}