{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:28:07Z","timestamp":1786987687404,"version":"build-2736575974"},"reference-count":46,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes & Metabolism"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.diabet.2014.02.002","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T08:46:45Z","timestamp":1396428405000},"page":"331-337","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":98,"title":["Update on cognitive decline and dementia in elderly patients with diabetes"],"prefix":"10.1016","volume":"40","author":[{"given":"L.","family":"Bordier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Doucet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Boudet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Bauduceau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabet.2014.02.002_bib0005","series-title":"Pr\u00e9valence et incidence du diab\u00e8te, et mortalit\u00e9 li\u00e9e au diab\u00e8te en France. Synth\u00e8se \u00e9pid\u00e9miologique","author":"Fagot-Campagna","year":"2010"},{"key":"10.1016\/j.diabet.2014.02.002_bib0010","first-page":"405","article-title":"PAQUID. Prevalence of dementia and Alzheimer's disease among subjects aged 75years or over: updated results of the PAQUID cohort","volume":"159","author":"Ramaroson","year":"2003","journal-title":"Rev Neurol"},{"key":"10.1016\/j.diabet.2014.02.002_bib0015","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.diabet.2012.07.001","article-title":"GERODIAB: Glycaemic control and 5-year morbidity\/mortality of type\u00a02 diabetic patients aged 70years and older: 1. Description of the population at inclusion","volume":"38","author":"Doucet","year":"2012","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diabet.2014.02.002_bib0020","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1007\/s00125-005-0023-4","article-title":"Cognitive decline and dementia in diabetes\u2013systematic overview of prospective observational studies","volume":"48","author":"Cukierman","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabet.2014.02.002_bib0025","doi-asserted-by":"crossref","first-page":"e4144","DOI":"10.1371\/journal.pone.0004144","article-title":"Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis","volume":"4","author":"Lu","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.diabet.2014.02.002_bib0030","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1212\/WNL.0b013e3181a92c36","article-title":"Predictors of maintaining cognitive function in older adults: the Health ABC study","volume":"72","author":"Yaffe","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.diabet.2014.02.002_bib0035","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.archger.2008.01.005","article-title":"Somatic chronic diseases and 6-year change in cognitive functioning among older persons","volume":"48","author":"Comijs","year":"2009","journal-title":"Arch Gerontol Geriatr"},{"key":"10.1016\/j.diabet.2014.02.002_bib0040","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jalz.2009.01.027","article-title":"Atherosclerosis risk in communities study brain MRI study. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study","volume":"5","author":"Knopman","year":"2009","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.diabet.2014.02.002_bib0045","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s00125-011-2095-7","article-title":"Glycated haemoglobin and cognitive decline: the Atherosclerosis Risk in Communities (ARIC) study","volume":"54","author":"Christman","year":"2011","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabet.2014.02.002_bib0050","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-Mental-State. A practical method for grading the cognitive state on patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.diabet.2014.02.002_bib0055","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1136\/jnnp.2007.136903","article-title":"Risk profiles for mild cognitive impairment and progression to dementia are gender specific","volume":"79","author":"Artero","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.diabet.2014.02.002_bib0060","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.2337\/db10-0539","article-title":"Accelerated progression from mild cognitive impairment to dementia in people with diabetes","volume":"59","author":"Xu","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.diabet.2014.02.002_bib0065","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1111\/j.1365-2796.2004.01380.x","article-title":"Mild cognitive impairment\u2013beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment","volume":"256","author":"Winblad","year":"2004","journal-title":"J Intern Med"},{"key":"10.1016\/j.diabet.2014.02.002_bib0070","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S1474-4422(05)70284-2","article-title":"Risk of dementia in diabetes mellitus: a systematic review","volume":"5","author":"Biessels","year":"2006","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.diabet.2014.02.002_bib0075","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1001\/archneurol.2007.29","article-title":"Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study. Cognition Study","volume":"65","author":"Irie","year":"2008","journal-title":"Arch Neurol"},{"key":"10.1016\/j.diabet.2014.02.002_bib0080","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s12603-011-0057-x","article-title":"Improved diabetes control in elderly delays global cognitive decline","volume":"15","author":"Luchsinger","year":"2012","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.diabet.2014.02.002_bib0085","first-page":"297","article-title":"Glycaemia and cognitive function in older adults using glucose-lowering drugs","volume":"10","author":"Shorr","year":"2006","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.diabet.2014.02.002_bib0090","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1001\/archneurol.2012.1117","article-title":"Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia","volume":"69","author":"Yaffe","year":"2012","journal-title":"Arch Neurol"},{"key":"10.1016\/j.diabet.2014.02.002_bib0095","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2337\/diacare.29.02.06.dc05-1626","article-title":"Improving metabolic control leads to better working memory in adults with type 2 diabetes","volume":"29","author":"Ryan","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2014.02.002_bib0100","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2337\/dc08-1153","article-title":"Relationship between baseline glycaemic control and cognitive function in individuals with type 2 diabetes and other cardiovascular risk factors: the action to control cardiovascular risk in diabetes-memory in diabetes (ACCORD-MIND) trial","volume":"32","author":"Cukierman-Yaffe","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2014.02.002_bib0105","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/S1474-4422(11)70188-0","article-title":"Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomized open-label study","volume":"10","author":"Launer","year":"2001","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.diabet.2014.02.002_bib0110","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1464-5491.2011.03505.x","article-title":"Edinburgh Type 2 severe hypoglycaemia and late-life cognitive ability in older people with type 2 diabetes: the Edinburgh Type 2 diabetes study","volume":"29","author":"Aung","year":"2012","journal-title":"Diabetes Med"},{"key":"10.1016\/j.diabet.2014.02.002_bib0115","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1001\/jama.2009.460","article-title":"Hypoglycaemic episodes and risk of dementia in older patients with type 2 diabetes mellitus","volume":"301","author":"Whitmer","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.diabet.2014.02.002_bib0120","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1056\/NEJMoa066397","article-title":"Long-term effect of diabetes and its treatment on cognitive function","volume":"356","author":"Diabetes Control and Complications Trial\/Epidemiology of Diabetes Interventions and Complications Study Research Group","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabet.2014.02.002_bib0125","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1007\/s00125-009-1484-7","article-title":"Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial","volume":"52","author":"de Galan","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabet.2014.02.002_bib0130","doi-asserted-by":"crossref","first-page":"787","DOI":"10.2337\/dc11-1855","article-title":"Poor cognitive function and risk of severe hypoglycaemia in type 2 diabetes: post hoc epidemiologic analysis of the ACCORD trial","volume":"35","author":"Punthakee","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2014.02.002_bib0135","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1111\/j.1532-5415.2011.03726.x","article-title":"Risk of hypoglycaemia in older veterans with dementia and cognitive impairment: implications for practice and policy","volume":"59","author":"Feil","year":"2011","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.diabet.2014.02.002_bib0140","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1007\/s00125-009-1437-1","article-title":"Severe hypoglycaemia and cognitive impairment in older patients with diabetes: the Fremantle Diabetes Study","volume":"52","author":"Bruce","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabet.2014.02.002_bib0145","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nrendo.2010.228","article-title":"Cognitive function, dementia and type 2 diabetes mellitus in the elderly","volume":"7","author":"Strachan","year":"2011","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.diabet.2014.02.002_bib0150","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1161\/STR.0b013e3182299496","article-title":"Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"42","author":"Gorelick","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.diabet.2014.02.002_bib0155","doi-asserted-by":"crossref","first-page":"S185","DOI":"10.3233\/JAD-2012-111433","article-title":"Type 2 diabetes and cognitive impairment: linking mechanisms","volume":"30","author":"Luchsinger","year":"2012","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.diabet.2014.02.002_bib0160","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1212\/WNL.0b013e3182315a56","article-title":"Advanced glycation end product level, diabetes, and accelerated cognitive aging","volume":"7","author":"Yaffe","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.diabet.2014.02.002_bib0165","doi-asserted-by":"crossref","first-page":"147","DOI":"10.2174\/156720507780362137","article-title":"Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment","volume":"4","author":"Craft","year":"2007","journal-title":"Curr Alzheimer Res"},{"key":"10.1016\/j.diabet.2014.02.002_bib0170","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.physbeh.2010.01.004","article-title":"Mini-review: impact of recurrent hypoglycaemia on cognitive and brain function","volume":"100","author":"McNay","year":"2010","journal-title":"Physiol Behav"},{"key":"10.1016\/j.diabet.2014.02.002_bib0175","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.diabet.2009.02.003","article-title":"SFGG French-speaking group for study of diabetes in the elderly. A call to incorporate the prevention and treatment of geriatric disorders in the management of diabetes in the elderly","volume":"35","author":"Vischer","year":"2009","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diabet.2014.02.002_bib0180","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2318-6-8","article-title":"The impact of cognitive functioning on mortality and the development of functional disability in older adults with diabetes: the second longitudinal study on aging","volume":"6","author":"McGuire","year":"2006","journal-title":"BMC Geriatr"},{"key":"10.1016\/j.diabet.2014.02.002_bib0185","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1001\/archinte.167.11.1137","article-title":"Diabetes mellitus, glycaemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study","volume":"167","author":"Maraldi","year":"2007","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.diabet.2014.02.002_bib0190","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.2337\/dc06-0506","article-title":"Cognitive dysfunction is associated with poor diabetes control in older adults","volume":"29","author":"Munshi","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabet.2014.02.002_bib0195","first-page":"497","article-title":"Diabetes mellitus in older people: Position statement on behalf of the International Association of Gerontology and Geriatrics (IAGG), the European Diabetes Working Party for Older People (EDWPOP) and the International task force of experts in diabetes","volume":"13","author":"Sinclair","year":"2012","journal-title":"JAMDA"},{"issue":"Suppl.\u00a03","key":"10.1016\/j.diabet.2014.02.002_bib0200","doi-asserted-by":"crossref","first-page":"S27","DOI":"10.1016\/S1262-3636(11)70962-4","article-title":"European Diabetes Working Party for Older People. Clinical guidelines for type 2 diabetes mellitus. Executive summary","volume":"37","author":"Sinclair","year":"2011","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diabet.2014.02.002_bib0205","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1007\/s00125-012-2534-0","article-title":"Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)","volume":"55","author":"Inzucchi","year":"2012","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabet.2014.02.002_bib0210","series-title":"Strat\u00e9gie m\u00e9dicamenteuse du contr\u00f4le glyc\u00e9mique du diab\u00e8te de type 2. Recommandations de bonne pratique","author":"Haute Autorit\u00e9 de sant\u00e9","year":"2013"},{"key":"10.1016\/j.diabet.2014.02.002_bib0215","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1111\/jgs.12035","article-title":"Diabetes in older adults: a consensus report","volume":"60","author":"Kirkman","year":"2012","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.diabet.2014.02.002_bib0220","first-page":"1141","article-title":"Le Mini-Mental State Examination (MMSE)\u00a0: un outil pratique pour l\u2019\u00e9valuation de l\u2019\u00e9tat cognitif des patients par le clinicien. Version fran\u00e7aise consensuelle","volume":"21","author":"Derouesn\u00e9","year":"1999","journal-title":"Presse Med"},{"key":"10.1016\/j.diabet.2014.02.002_bib0225","series-title":"R\u00e9\u00e9valuation des m\u00e9dicaments indiqu\u00e9s dans le traitement de la maladie d\u2019Alzheimer","author":"Haute Autorit\u00e9 de sant\u00e9","year":"2011"},{"key":"10.1016\/j.diabet.2014.02.002_bib0230","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1093\/ageing\/afp056","article-title":"SGS: a structured treatment and teaching programme for older patients with diabetes mellitus \u2013 a prospective randomized controlled multi-centre trial","volume":"38","author":"Braun","year":"2009","journal-title":"Age Ageing"}],"container-title":["Diabetes & Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1262363614000366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1262363614000366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:55:11Z","timestamp":1761130511000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1262363614000366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S1262363614000366"],"URL":"https:\/\/doi.org\/10.1016\/j.diabet.2014.02.002","relation":{},"ISSN":["1262-3636"],"issn-type":[{"value":"1262-3636","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Update on cognitive decline and dementia in elderly patients with diabetes","name":"articletitle","label":"Article Title"},{"value":"Diabetes & Metabolism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diabet.2014.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}