{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:49:15Z","timestamp":1758278955236},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1016\/j.diabres.2003.10.018","type":"journal-article","created":{"date-parts":[[2003,12,30]],"date-time":"2003-12-30T11:00:20Z","timestamp":1072782020000},"page":"191-199","source":"Crossref","is-referenced-by-count":9,"title":["Mild renal insufficiency as a cardiovascular risk factor in non-proteinuric type II diabetes"],"prefix":"10.1016","volume":"64","author":[{"given":"Jos\u00e9 A.","family":"Gimeno-Orna","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M.","family":"Lou-Arnal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Boned-Juliani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmundo","family":"Molinero-Herguedas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabres.2003.10.018_BIB1","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1056\/NEJMcp011773","article-title":"Nephropathy in patients with type II diabetes","volume":"346","author":"Remuzzi","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB2","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1464-5491.1995.tb00446.x","article-title":"Proteinuria and mortality in diabetes: the WHO multinational study of vascular disease in diabetes","volume":"12","author":"Stephenson","year":"1995","journal-title":"Diab. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB3","doi-asserted-by":"crossref","unstructured":"E. Casiglia, G. Zanette, A. Mazza et al., Cardiovascular mortality in non-insulin dependent diabetes mellitus. A controlled study among 683 diabetics and 683 age- and sex-matched normal subjects. Eur. J. Epidemiol. (2000) 677\u2013684.","DOI":"10.1023\/A:1007673123716"},{"key":"10.1016\/j.diabres.2003.10.018_BIB4","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1001\/archinte.160.8.1093","article-title":"The risk of cardiovascular disease mortality associated with microalbuminuria and gross proteinuria in persons with older onset diabetes mellitus","volume":"160","author":"Valmadrid","year":"2000","journal-title":"Arch. Intern. Med."},{"issue":"3","key":"10.1016\/j.diabres.2003.10.018_BIB5","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/ajkd.1998.v32.pm9820470","article-title":"Clinical epidemiology of cardiovascular disease in chronic renal disease","volume":"32","author":"Foley","year":"1998","journal-title":"Am. J. Kidney Dis."},{"key":"10.1016\/j.diabres.2003.10.018_BIB6","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1056\/NEJM199809173391211","article-title":"Chronic renal failure: a vasculopathic state (editorial)","volume":"339","author":"Luke","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB7","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1523-1755.2002.kid571.x","article-title":"Mild renal insufficiency is associated with increased cardiovascular mortality: the Hoorn Study","volume":"62","author":"Henry","year":"2002","journal-title":"Kidney Int."},{"key":"10.1016\/j.diabres.2003.10.018_BIB8","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1046\/j.1523-1755.1999.00773.x","article-title":"Cardiovascular disease and mortality in a community based cohort with mild renal insufficiency","volume":"56","author":"Culleton","year":"1999","journal-title":"Kidney Int."},{"key":"10.1016\/j.diabres.2003.10.018_BIB9","unstructured":"J.A., Gimeno, B., Boned, L.M., Lou, F.J., Castro, Microalbuminuria and clinic proteinuria as main cardiovascular morbimortality predictors in type II diabetic patients. Rev. Clin. Esp, in press."},{"key":"10.1016\/j.diabres.2003.10.018_BIB10","unstructured":"World Health Organization Study Group on Diabetes Mellitus, Technical report series 727 (1985) WHO, Geneva."},{"key":"10.1016\/j.diabres.2003.10.018_BIB11","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1159\/000180580","article-title":"Prediction of creatinine clearance from serum creatinine","volume":"16","author":"Cockroft","year":"1976","journal-title":"Nephron"},{"key":"10.1016\/j.diabres.2003.10.018_BIB12","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/00000441-199903000-00007","article-title":"Abnormalities of kidney function as a cause and a consequence of cardiovascular disease","volume":"317","author":"Hall","year":"1999","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.diabres.2003.10.018_BIB13","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/00000441-200209000-00004","article-title":"Primary renal disease as a cardiovascular risk factor","volume":"324","author":"Crook","year":"2002","journal-title":"Am. J. Med. Sci."},{"key":"10.1016\/j.diabres.2003.10.018_BIB14","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s11906-002-0065-7","article-title":"Renal dysfunction as a cardiovascular risk factor","volume":"4","author":"Ritz","year":"2002","journal-title":"Curr. Hypertens. Rep."},{"key":"10.1016\/j.diabres.2003.10.018_BIB15","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3810\/pgm.2002.04.1168","article-title":"Cardiovascular disease and the kidney. Tracking a killer in chronic kidney disease","volume":"111","author":"Levin","year":"2002","journal-title":"Postgrad. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB16","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1046\/j.1523-1755.2002.00270.x","article-title":"Moderate renal insufficiency and the risk of cardiovascular mortality: results from the NHANES I","volume":"61","author":"Garg","year":"2002","journal-title":"Kidney Int."},{"key":"10.1016\/j.diabres.2003.10.018_BIB17","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1001\/jama.279.8.585","article-title":"Risk factors for 5-year mortality in older adults: the cardiovascular health study","volume":"279","author":"Fried","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.diabres.2003.10.018_BIB18","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1001\/archinte.161.6.886","article-title":"High-normal serum creatinine concentration is a predictor of cardiovascular risk in essential hypertension","volume":"161","author":"Schillaci","year":"2001","journal-title":"Arch. Int. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.7326\/0003-4819-134-8-200104170-00007","article-title":"Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: the HOPE randomized trial","volume":"134","author":"Mann","year":"2001","journal-title":"Ann. Int. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB20","doi-asserted-by":"crossref","first-page":"1.413","DOI":"10.1001\/archinte.1997.00440340025002","article-title":"The association of microalbuminuria and mortality in non insulin dependent diabetes mellitus. A systematic overview of the literature","volume":"157","author":"Dinneen","year":"1997","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB21","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1056\/NEJM199807233390404","article-title":"Mortality from coronary heart disease in subjects with type II diabetes and in nondiabetic subjects with and without prior myocardial infarction","volume":"339","author":"Haffner","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB22","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJM200003233421202","article-title":"C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women","volume":"342","author":"Ridker","year":"2000","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.diabres.2003.10.018_BIB23","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S1047-2797(01)00208-3","article-title":"Accuracy of lipoprotein lipids and apoproteins in predicting coronary heart disease in diabetic American Indians. The strong heart study","volume":"12","author":"Hu","year":"2002","journal-title":"Ann. Epidemiol."},{"key":"10.1016\/j.diabres.2003.10.018_BIB24","doi-asserted-by":"crossref","first-page":"79","DOI":"10.2337\/diacare.19.1.79","article-title":"Microalbuminuria in patients with NIDDM: an overview","volume":"19","author":"Alzaid","year":"1996","journal-title":"Diab. Care"},{"key":"10.1016\/j.diabres.2003.10.018_BIB25","doi-asserted-by":"crossref","unstructured":"Heart Outcomes Prevention Evaluation (HOPE) Study Investigators: Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO\u2013HOPE substudy. Lancet 355 (2000) 253\u2013259.","DOI":"10.1016\/S0140-6736(99)12323-7"},{"key":"10.1016\/j.diabres.2003.10.018_BIB26","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0140-6736(02)08089-3","article-title":"Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol","volume":"359","author":"Dahl\u00f6f","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.diabres.2003.10.018_BIB27","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.2337\/diabetes.49.9.1399","article-title":"The need for early predictors of diabetic nephropathy risk","volume":"49","author":"Caramori","year":"2000","journal-title":"Diabetes"},{"key":"10.1016\/j.diabres.2003.10.018_BIB28","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/s001250050616","article-title":"Patterns of renal injury in NIDDM patients with microalbuminuria","volume":"39","author":"Fioretto","year":"1996","journal-title":"Diabetologia"}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822703002894?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822703002894?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T05:01:54Z","timestamp":1553749314000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822703002894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S0168822703002894"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2003.10.018","relation":{},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}