{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:32:32Z","timestamp":1789749152281,"version":"4.0.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1016\/j.diabres.2007.12.001","type":"journal-article","created":{"date-parts":[[2008,1,11]],"date-time":"2008-01-11T11:03:15Z","timestamp":1200049395000},"page":"218-223","source":"Crossref","is-referenced-by-count":24,"title":["Necrotizing fasciitis: A life-threatening clinical disorder in uncontrolled type 2 diabetic patients"],"prefix":"10.1016","volume":"80","author":[{"given":"O.","family":"Oncul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Erenoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Top","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"K\u00fc\u00e7\u00fckardal\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Karabudak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Kurt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.L.","family":"Akin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Cavuslu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Celenk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabres.2007.12.001_bib1","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/bjs.1800780431","article-title":"Necrotizing fasciitis: 10 years experience in a distinct general hospital","volume":"78","author":"Ward","year":"1991","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.diabres.2007.12.001_bib2","unstructured":"From the Centers for Disease Control and Prevention: Morbidity and Mortality Weekly Report. Nosocomial Group A Streptococcal Infections Associated With Asymptomatic Health-Care Workers\u2014Maryland and California, 1997. JAMA. 281 (1999) 1077\u20131078."},{"key":"10.1016\/j.diabres.2007.12.001_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0168-8227(97)00125-3","article-title":"Unusual infections in diabetes","volume":"39","author":"Rajbhandari","year":"1998","journal-title":"Diabetes Res. Clin. Pract."},{"key":"10.1016\/j.diabres.2007.12.001_bib4","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1046\/j.1464-410x.1998.00532.x","article-title":"Fournier's gangrene","volume":"81","author":"Smith","year":"1998","journal-title":"B.J.U. Int."},{"key":"10.1016\/j.diabres.2007.12.001_bib5","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0090-4295(02)01951-9","article-title":"Impact of Diabetes mellitus on the presentation and outcomes of Fournier's Gangrene","volume":"60","author":"Nisbet","year":"2002","journal-title":"Adult Urol."},{"key":"10.1016\/j.diabres.2007.12.001_bib6","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/S0002-9343(97)00160-5","article-title":"Population based surveillance for Group A Streptococcal necrotising fasciitis: clinical features, prognostic indicators and microbiological analysis of seventy seven cases","volume":"103","author":"Kaul","year":"1997","journal-title":"Am. J. Med."},{"key":"10.1016\/j.diabres.2007.12.001_bib7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.0022-202X.2004.22711.x","article-title":"Diabetes prolongs the imflammatory response to a bacterial stimulus through cytokine dysregulation","volume":"123","author":"Nagurib","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.diabres.2007.12.001_bib8","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1189\/jlb.0104050","article-title":"In vivo evidences that insulin regulates human polymorphonuclear neutrophil functions","volume":"76","author":"Walrand","year":"2004","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.diabres.2007.12.001_bib9","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jdiacomp.2006.08.006","article-title":"Management of necrotizing fasciitis in diabetic patients","volume":"21","author":"G\u00fcrlek","year":"2007","journal-title":"J. Diabetes Complications"},{"key":"10.1016\/j.diabres.2007.12.001_bib10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0001-706X(01)00173-5","article-title":"Necrotizing fasciitis: a 10-year retrospective study of cases in a single university hospital in Oman","volume":"80","author":"Rangaswamy","year":"2001","journal-title":"Acta Trop."},{"key":"10.1016\/j.diabres.2007.12.001_bib11","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1146\/annurev.med.51.1.271","article-title":"Streptococcal toxic shock syndrome associated with necrotizing fasciitis","volume":"51","author":"Stevens","year":"2000","journal-title":"Ann. Rev. Med."},{"key":"10.1016\/j.diabres.2007.12.001_bib12","first-page":"111","article-title":"Emerging infectious diseases-challenge to all","volume":"55","author":"Strausbaugh","year":"1997","journal-title":"Am. Fam. Physicians"},{"key":"10.1016\/j.diabres.2007.12.001_bib13","first-page":"393","article-title":"Are the principles of treatment of chronic osteitis applicable to the diabetic foot?","volume":"31","author":"Senneville","year":"2002","journal-title":"Presse Med."},{"key":"10.1016\/j.diabres.2007.12.001_bib14","first-page":"541","article-title":"Alterations in natural immunity and risk of infection in patients with diabetes mellitus","volume":"60","author":"Moutschen","year":"2005","journal-title":"Rev. Med. Liege."},{"key":"10.1016\/j.diabres.2007.12.001_bib15","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jinf.2006.05.004","article-title":"Effect of the function of polymorphonuclear leukocytes and interleukin-1 beta on wound healing in patients with diabetic foot infections","volume":"54","author":"Oncul","year":"2007","journal-title":"J. Infect."},{"key":"10.1016\/j.diabres.2007.12.001_bib16","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0302-2838(03)00102-7","article-title":"Fournier's gangrene: an analysis of repeated surgical debridement","volume":"43","author":"Chawla","year":"2003","journal-title":"Eur. Urol."},{"key":"10.1016\/j.diabres.2007.12.001_bib17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1445-2197.2006.03975.x","article-title":"Factors affecting mortality of Fournier's gangrene: review of 70 patients","volume":"77","author":"Ersay","year":"2007","journal-title":"A.N.Z. J. Surg."},{"key":"10.1016\/j.diabres.2007.12.001_bib18","first-page":"83","article-title":"Nekrotizan yumu\u015fak doku infeksiyonlar\u0131: bir e\u011fitim hastanesi genel cerrahi klini\u011finde be\u015f y\u0131ll\u0131k tedavi sonu\u00e7lar\u0131","volume":"4","author":"Bozkurt","year":"2001","journal-title":"\u0130nsizyon Cerrahi T\u0131p Bilimleri Dergisi"},{"key":"10.1016\/j.diabres.2007.12.001_bib19","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0002-9610(01)00785-1","article-title":"Burn center management of necrotizing soft-tissue surgical infection in unburned patients","volume":"182","author":"Faucher","year":"2001","journal-title":"Am. J. Surg."},{"key":"10.1016\/j.diabres.2007.12.001_bib20","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1097\/00006534-199905060-00003","article-title":"Clinical experience with 20 cases of Group A Streptococcus necrotizing fasciitis and myonecrosis: 1995\u20131997","volume":"103","author":"Haywood","year":"1999","journal-title":"Plast. Reconstr. Surg."},{"key":"10.1016\/j.diabres.2007.12.001_bib21","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/110241598750004463","article-title":"Hyprbaric oxygen in the treatment of Fournier's gangrene","volume":"164","author":"Korhonen","year":"1998","journal-title":"Eur. J. Surg."},{"key":"10.1016\/j.diabres.2007.12.001_bib22","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1007\/s00268-005-0777-3","article-title":"Fournier's Gangrene: Risk factors and strategies for management","volume":"30","author":"Yanar","year":"2006","journal-title":"World J. Surg."}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822707006122?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822707006122?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T10:22:45Z","timestamp":1546338165000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822707006122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S0168822707006122"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2007.12.001","relation":{},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}