{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:47:43Z","timestamp":1790164063248,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.diabres.2011.08.029","type":"journal-article","created":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T14:01:18Z","timestamp":1320933678000},"page":"275-282","source":"Crossref","is-referenced-by-count":42,"title":["Metabolic syndrome in adult cancer survivors: A meta-analysis"],"prefix":"10.1016","volume":"95","author":[{"given":"Hyun-Suk","family":"Jung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Kwon","family":"Myung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Su","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Gwan","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabres.2011.08.029_bib0005","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/S1470-2045(07)70246-2","article-title":"Recent cancer survival in Europe: a 2000\u201302 period analysis of EUROCARE-4 data","volume":"8","author":"Verdecchia","year":"2007","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0010","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1056\/NEJMsa060185","article-title":"Chronic health conditions in adult survivors of childhood cancer","volume":"355","author":"Oeffinger","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diabres.2011.08.029_bib0015","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1200\/JCO.2003.04.173","article-title":"Cardiovascular disease as a long-term complication of treatment for testicular cancer","volume":"21","author":"Huddart","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0020","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1210\/jc.81.8.3051","article-title":"Long-term survivors of childhood cancer have an increased risk of manifesting the metabolic syndrome","volume":"81","author":"Talvensaari","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2011.08.029_bib0025","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1200\/JCO.2000.18.8.1725","article-title":"Cardiovascular morbidity in long-term survivors of metastatic testicular cancer","volume":"18","author":"Meinardi","year":"2000","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0030","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.jacc.2006.09.032","article-title":"Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies","volume":"49","author":"Gami","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0035","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1365-2796.2010.02325.x","article-title":"The metabolic syndrome: time to get off the merry-go-round?","volume":"269","author":"Reaven","year":"2011","journal-title":"J Intern Med"},{"key":"10.1016\/j.diabres.2011.08.029_bib0040","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.1200\/JCO.2005.02.176","article-title":"The metabolic syndrome and disturbances in hormone levels in long-term survivors of disseminated testicular cancer","volume":"23","author":"Nuver","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0045","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1200\/JCO.2006.05.9741","article-title":"Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy","volume":"24","author":"Braga-Basaria","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0050","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1210\/jc.2005-2298","article-title":"Improvement in cardiac systolic function and reduced prevalence of metabolic syndrome after two years of growth hormone (GH) treatment in GH-deficient adult survivors of childhood-onset acute lymphoblastic leukemia","volume":"91","author":"Follin","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2011.08.029_bib0055","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1002\/cncr.22120","article-title":"Metabolic syndrome and growth hormone deficiency in adult survivors of childhood acute lymphoblastic leukemia","volume":"107","author":"Gurney","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.diabres.2011.08.029_bib0060","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/annonc\/mdl372","article-title":"Components of the metabolic syndrome in long-term survivors of testicular cancer","volume":"18","author":"Haugnes","year":"2007","journal-title":"Ann Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0065","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/sj.bmt.1705972","article-title":"Prevalence of metabolic syndrome in long-term survivors of hematopoietic stem cell transplantation","volume":"41","author":"Annaloro","year":"2008","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.diabres.2011.08.029_bib0070","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/pbc.21363","article-title":"Metabolic syndrome traits in long-term survivors of pediatric sarcoma","volume":"50","author":"Hoffman","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.diabres.2011.08.029_bib0075","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/IGC.0b013e3181a13058","article-title":"Prevalence and determinants of metabolic syndrome and elevated Framingham risk score in epithelial ovarian cancer survivors: a controlled observational study","volume":"19","author":"Liavaag","year":"2009","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.diabres.2011.08.029_bib0080","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/bmt.2008.263","article-title":"High prevalence of metabolic syndrome after allogeneic hematopoietic cell transplantation","volume":"43","author":"Majhail","year":"2009","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.diabres.2011.08.029_bib0085","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0305-7372(02)00038-5","article-title":"The metabolic syndrome in long-term cancer survivors, an important target for secondary preventive measures","volume":"28","author":"Nuver","year":"2002","journal-title":"Cancer Treat Rev"},{"key":"10.1016\/j.diabres.2011.08.029_bib0090","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S1470-2045(09)70287-6","article-title":"The metabolic syndrome in cancer survivors","volume":"11","author":"de Haas","year":"2010","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0095","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.diabres.2011.08.029_bib0100","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.diabres.2011.08.029_bib0105","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1210\/jc.2005-2298","article-title":"Improvement in cardiac systolic function and reduced prevalence of metabolic syndrome after two years of growth hormone (GH) treatment in GH-deficient adult survivors of childhood-onset acute lymphoblastic leukemia","volume":"91","author":"Follin","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2011.08.029_bib0110","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/pbc.21936","article-title":"Obesity and metabolic changes are common in young childhood brain tumor survivors","volume":"52","author":"Pietil\u00e4","year":"2009","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.diabres.2011.08.029_bib0115","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1200\/JCO.2003.06.131","article-title":"Childhood Cancer Survivor Study. Obesity in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study","volume":"21","author":"Oeffinger","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0120","doi-asserted-by":"crossref","first-page":"4731","DOI":"10.1210\/jc.2003-030784","article-title":"Final height and body mass index among adult survivors of childhood brain cancer: childhood cancer survivor study","volume":"88","author":"Gurney","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2011.08.029_bib0125","doi-asserted-by":"crossref","first-page":"3816","DOI":"10.1210\/jc.2006-2178","article-title":"Abdominal obesity, liver fat, and muscle composition in survivors of childhood acute lymphoblastic leukemia","volume":"92","author":"Janiszewski","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2011.08.029_bib0130","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1136\/adc.76.4.298","article-title":"Relationship between cardiopulmonary response to exercise and adiposity in survivors of childhood malignancy","volume":"76","author":"Warner","year":"1997","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.diabres.2011.08.029_bib0135","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000023566","article-title":"Energy expenditure, energy intake and prevalence of obesity after therapy for acute lymphoblastic leukemia during childhood","volume":"53","author":"Mayer","year":"2000","journal-title":"Horm Res"},{"key":"10.1016\/j.diabres.2011.08.029_bib0140","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1365-2265.1999.00622.x","article-title":"Hyperleptinaemia in young adults following cranial irradiation in childhood: growth hormone deficiency or leptin insensitivity?","volume":"50","author":"Brennan","year":"1999","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0145","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1161\/CIRCULATIONAHA.105.588327","article-title":"Magnesium intake and incidence of metabolic syndrome among young adults","volume":"113","author":"He","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.diabres.2011.08.029_bib0150","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1038\/sj.bjc.6601344","article-title":"Severe intracellular magnesium and potassium depletion in patients after treatment with cisplatin","volume":"89","author":"Lajer","year":"2003","journal-title":"Br J Cancer"},{"key":"10.1016\/j.diabres.2011.08.029_bib0155","doi-asserted-by":"crossref","first-page":"9130","DOI":"10.1200\/JCO.2005.01.4092","article-title":"Acute chemotherapy-induced cardiovascular changes in patients with testicular cancer","volume":"23","author":"Nuver","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0160","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1161\/CIRCULATIONAHA.105.563213","article-title":"Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms","volume":"113","author":"Kim","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.diabres.2011.08.029_bib0165","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1200\/JCO.2008.21.1482","article-title":"Physical performance limitations in the Childhood Cancer Survivor Study cohort","volume":"27","author":"Ness","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0170","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10549-005-2418-9","article-title":"Obesity and cardiovascular risk factors in younger breast cancer survivors: the Cancer and Menopause Study (CAMS)","volume":"93","author":"Herman","year":"2005","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.diabres.2011.08.029_bib0175","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1182\/blood-2006-05-022335","article-title":"Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study","volume":"109","author":"Baker","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.diabres.2011.08.029_bib0180","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2141.2008.07165.x","article-title":"Cardiac cardiovascular consequences after haematopoietic stem cell transplantation","volume":"142","author":"Tichelli","year":"2008","journal-title":"Br J Haematol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0185","doi-asserted-by":"crossref","first-page":"3463","DOI":"10.1182\/blood-2006-10-054080","article-title":"Premature cardiovascular disease after allogeneic hematopoietic stem-cell transplantation","volume":"110","author":"Tichelli","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.diabres.2011.08.029_bib0190","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/sj.bmt.1701337","article-title":"Long-term effects of allogeneic bone marrow transplantation BMT on pituitary, gonad, thyroid and adrenal function in adults","volume":"22","author":"Kauppila","year":"1998","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.diabres.2011.08.029_bib0195","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/ije\/dyg179","article-title":"Association of the metabolic syndrome with both vigorous and moderate physical activity","volume":"32","author":"Rennie","year":"2003","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.diabres.2011.08.029_bib0200","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1002\/cncr.20960","article-title":"Body mass index in long-term adult survivors of childhood cancer: a report of the Childhood Cancer Survivor Study","volume":"103","author":"Meacham","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.diabres.2011.08.029_bib0205","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1464-5491.2006.01858.x","article-title":"Metabolic syndrome\u2014a new world-wide definition. A Consensus Statement from the International Diabetes Federation","volume":"23","author":"Alberti","year":"2006","journal-title":"Diabet Med"}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822711005651?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822711005651?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T07:11:36Z","timestamp":1560928296000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822711005651"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0168822711005651"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2011.08.029","relation":{},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}