{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:16:09Z","timestamp":1770740169837,"version":"3.49.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["diabetesresearchclinicalpractice.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.diabres.2014.08.014","type":"journal-article","created":{"date-parts":[[2014,9,5]],"date-time":"2014-09-05T05:24:29Z","timestamp":1409894669000},"page":"351-359","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Role of various indices derived from an oral glucose tolerance test in the prediction of conversion from prediabetes to type 2 diabetes"],"prefix":"10.1016","volume":"106","author":[{"given":"Ye An","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eu Jeong","family":"Ku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ah Reum","family":"Khang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Shil","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoung Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Hoon","family":"Moon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Hee","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyong Soo","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hak Chul","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4137-1671","authenticated-orcid":false,"given":"Soo","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabres.2014.08.014_bib0005","first-page":"A119","article-title":"Depression, diabetes, and chronic disease risk factors among US women of reproductive age","volume":"8","author":"Farr","year":"2011","journal-title":"Prev Chron Dis"},{"key":"10.1016\/j.diabres.2014.08.014_bib0010","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.mcna.2010.11.005","article-title":"Pathophysiology of prediabetes","volume":"95","author":"Ferrannini","year":"2011","journal-title":"Med Clin N Am"},{"key":"10.1016\/j.diabres.2014.08.014_bib0015","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.2337\/diacare.26.11.3160","article-title":"Follow-up report on the diagnosis of diabetes mellitus","volume":"26","author":"Genuth","year":"2003","journal-title":"Diabetes Care"},{"issue":"Suppl 1","key":"10.1016\/j.diabres.2014.08.014_bib0020","first-page":"S11","article-title":"Standards of medical care in diabetes\u20142010","volume":"33","year":"2010","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0025","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1046\/j.1464-5491.2002.00835.x","article-title":"Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and intervention","volume":"19","author":"Unwin","year":"2002","journal-title":"Diabetic Med J Br Diabetic Assoc"},{"key":"10.1016\/j.diabres.2014.08.014_bib0030","doi-asserted-by":"crossref","first-page":"2279","DOI":"10.1016\/S0140-6736(12)60283-9","article-title":"Prediabetes: a high-risk state for diabetes development","volume":"379","author":"Tabak","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.diabres.2014.08.014_bib0035","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0026-0495(89)90129-7","article-title":"Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake","volume":"38","author":"DeFronzo","year":"1989","journal-title":"Metabolism"},{"key":"10.1016\/j.diabres.2014.08.014_bib0040","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.2337\/diabetes.48.5.1198","article-title":"Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo","volume":"48","author":"Cherrington","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.diabres.2014.08.014_bib0045","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1172\/JCI111938","article-title":"Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus","volume":"76","author":"DeFronzo","year":"1985","journal-title":"J Clin Investig"},{"key":"10.1016\/j.diabres.2014.08.014_bib0050","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s00592-011-0285-x","article-title":"Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose","volume":"48","author":"Kanat","year":"2011","journal-title":"Acta Diabetol"},{"key":"10.1016\/j.diabres.2014.08.014_bib0055","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1111\/j.1464-5491.2010.03065.x","article-title":"Prediction models for incident type 2 diabetes mellitusin the older population: KORA S4\/F4 cohort study","volume":"27","author":"Rathmann","year":"2010","journal-title":"Diabetic Med J Br Diabetic Assoc"},{"key":"10.1016\/j.diabres.2014.08.014_bib0060","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1001\/archinte.167.10.1068","article-title":"Prediction of incident diabetes mellitus in middle-aged adults: the Framingham offspring study","volume":"167","author":"Wilson","year":"2007","journal-title":"Arch Int Med"},{"key":"10.1016\/j.diabres.2014.08.014_bib0065","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1093\/epirev\/mxq019","article-title":"Risk assessment tools for identifying individuals at risk of developing type 2 diabetes","volume":"33","author":"Buijsse","year":"2011","journal-title":"Epidemiol Rev"},{"key":"10.1016\/j.diabres.2014.08.014_bib0070","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.2337\/diacare.28.8.2013","article-title":"Identifying individuals at high risk for diabetes: the atherosclerosis risk in communities study","volume":"28","author":"Schmidt","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0075","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.2337\/dc06-1331","article-title":"What is the best predictor of future type 2 diabetes","volume":"30","author":"Abdul-Ghani","year":"2007","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0080","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.2337\/dc12-0246","article-title":"Patterns of insulin concentration during the OGTT predict the risk of type 2 diabetes in Japanese Americans","volume":"36","author":"Hayashi","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0085","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1007\/s00125-009-1407-7","article-title":"Glucose challenge test screening for prediabetes and undiagnosed diabetes","volume":"52","author":"Phillips","year":"2009","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabres.2014.08.014_bib0090","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabres.2014.08.014_bib0095","doi-asserted-by":"crossref","first-page":"295","DOI":"10.2337\/diacare.23.3.295","article-title":"Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity","volume":"23","author":"Stumvoll","year":"2000","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0100","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.2337\/diacare.22.9.1462","article-title":"Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp","volume":"22","author":"Matsuda","year":"1999","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0105","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1172\/JCI105534","article-title":"Insulin secretion in response to glycemic stimulus: relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus","volume":"46","author":"Seltzer","year":"1967","journal-title":"J Clin Investig"},{"key":"10.1016\/j.diabres.2014.08.014_bib0110","doi-asserted-by":"crossref","first-page":"335","DOI":"10.2337\/dc08-1478","article-title":"Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels","volume":"32","author":"Utzschneider","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0115","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.2337\/dc05-2179","article-title":"Contributions of beta-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose","volume":"29","author":"Abdul-Ghani","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0120","first-page":"2694","article-title":"A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome","volume":"83","author":"Legro","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2014.08.014_bib0125","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1210\/jcem.85.7.6661","article-title":"Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans","volume":"85","author":"Katz","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.diabres.2014.08.014_bib0130","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1002\/(SICI)1097-0258(19960530)15:10<969::AID-SIM211>3.0.CO;2-9","article-title":"Regret graphs, diagnostic uncertainty and Youden's index","volume":"15","author":"Hilden","year":"1996","journal-title":"Stat Med"},{"key":"10.1016\/j.diabres.2014.08.014_bib0135","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1089\/dia.2012.0259","article-title":"Associations of beta-cell function and insulin resistance with youth-onset type 2 diabetes and prediabetes among Asian Indians","volume":"15","author":"Mohan","year":"2013","journal-title":"Diabetes Technol Ther"},{"key":"10.1016\/j.diabres.2014.08.014_bib0140","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.2337\/diacare.20.12.1842","article-title":"Risk factors for the development of NIDDM in Yonchon County, Korea","volume":"20","author":"Shin","year":"1997","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0145","doi-asserted-by":"crossref","first-page":"89","DOI":"10.2337\/diacare.24.1.89","article-title":"Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development","volume":"24","author":"Weyer","year":"2001","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0150","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s00125-003-1169-6","article-title":"Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose tolerance","volume":"46","author":"Gastaldelli","year":"2003","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabres.2014.08.014_bib0155","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.1007\/s00125-005-1929-6","article-title":"K-value and low insulin secretion in a non-obese white population: predicted glucose tolerance after 25 years","volume":"48","author":"Alvarsson","year":"2005","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabres.2014.08.014_bib0160","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00125-002-1009-0","article-title":"The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes","volume":"46","author":"Kahn","year":"2003","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabres.2014.08.014_bib0165","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.diabres.2007.05.004","article-title":"Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: a systematic overview and meta-analysis of prospective studies","volume":"78","author":"Gerstein","year":"2007","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.diabres.2014.08.014_bib0170","doi-asserted-by":"crossref","first-page":"281","DOI":"10.2337\/dc08-1264","article-title":"Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia study","volume":"32","author":"Abdul-Ghani","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0175","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.2337\/dc08-0225","article-title":"One-hour plasma glucose concentration and the metabolic syndrome identify subjects at high risk for future type 2 diabetes","volume":"31","author":"Abdul-Ghani","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0180","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.2337\/diacare.28.11.2626","article-title":"The relation of fasting and 2-h postchallenge plasma glucose concentrations to mortality: data from the Baltimore Longitudinal Study of Aging with a critical review of the literature","volume":"28","author":"Sorkin","year":"2005","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0185","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1007\/s00125-013-2902-4","article-title":"Progression rates from HbA1c 6.0\u20136.4% and other prediabetes definitions to type 2 diabetes: a meta-analysis","volume":"56","author":"Morris","year":"2013","journal-title":"Diabetologia"},{"key":"10.1016\/j.diabres.2014.08.014_bib0190","doi-asserted-by":"crossref","first-page":"868","DOI":"10.2337\/diacare.26.3.868","article-title":"Insulin secretion and insulin sensitivity pattern is different in isolated impaired glucose tolerance and impaired fasting glucose the risk factor in impaired glucose tolerance for atherosclerosis and diabetes study","volume":"26","author":"Hanefeld","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2014.08.014_bib0195","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.2337\/dc12-0747","article-title":"HbA(1c) diagnostic categories and beta-cell function relative to insulin sensitivity in overweight\/obese adolescents","volume":"35","author":"Sjaarda","year":"2012","journal-title":"Diabetes Care"},{"issue":"Suppl 1","key":"10.1016\/j.diabres.2014.08.014_bib0200","doi-asserted-by":"crossref","first-page":"S212","DOI":"10.2337\/diabetes.51.2007.S212","article-title":"Accurate assessment of beta-cell function: the hyperbolic correction","volume":"51","author":"Bergman","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.diabres.2014.08.014_bib0205","first-page":"E241","article-title":"Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans","volume":"257","author":"Luzi","year":"1989","journal-title":"Am J Physiol"},{"key":"10.1016\/j.diabres.2014.08.014_bib0210","doi-asserted-by":"crossref","first-page":"E917","DOI":"10.1152\/ajpendo.00427.2001","article-title":"Acute hyperglycemia alters the ability of the normal beta-cell to sense and respond to glucose","volume":"282","author":"Meyer","year":"2002","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.diabres.2014.08.014_bib0215","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.2337\/dc12-1861","article-title":"One-hour glucose during an oral glucose challenge prospectively predicts beta-cell deterioration and prediabetes in obese Hispanic youth","volume":"36","author":"Kim","year":"2013","journal-title":"Diabetes Care"}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822714003775?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822714003775?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T23:21:45Z","timestamp":1538263305000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822714003775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0168822714003775"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2014.08.014","relation":{},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of various indices derived from an oral glucose tolerance test in the prediction of conversion from prediabetes to type 2 diabetes","name":"articletitle","label":"Article Title"},{"value":"Diabetes Research and Clinical Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diabres.2014.08.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}