{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:33:47Z","timestamp":1780533227844,"version":"3.54.1"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","diabetesresearchclinicalpractice.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.diabres.2023.110736","type":"journal-article","created":{"date-parts":[[2023,6,3]],"date-time":"2023-06-03T05:57:11Z","timestamp":1685771831000},"page":"110736","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Neuropathy in adolescents with type 1 diabetes: Confirmatory diagnostic tests, bedside tests, and risk factors"],"prefix":"10.1016","volume":"201","author":[{"given":"Vinni Faber","family":"Rasmussen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3557-6566","authenticated-orcid":false,"given":"Mathilde","family":"Thrys\u00f8e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens Randel","family":"Nyengaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice","family":"Tankisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7082-9576","authenticated-orcid":false,"given":"P\u00e1ll","family":"Karlsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Krogh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Brock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0104-4884","authenticated-orcid":false,"given":"Konstantinos","family":"Kamperis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4269-7550","authenticated-orcid":false,"given":"Mette","family":"Madsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1263-6850","authenticated-orcid":false,"given":"Wolfgang","family":"Singer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esben Thyssen","family":"Vestergaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Kristensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Astrid Juhl","family":"Terkelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.diabres.2023.110736_b0005","doi-asserted-by":"crossref","first-page":"98","DOI":"10.34172\/hpp.2020.18","article-title":"Prevalence and incidence of type 1 diabetes in the world: A systematic review and meta-analysis","volume":"10","author":"Mobasseri","year":"2020","journal-title":"Health Promot Perspect"},{"issue":"10","key":"10.1016\/j.diabres.2023.110736_b0010","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S2213-8587(22)00218-2","article-title":"Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study","volume":"10","author":"Gregory","year":"2022","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.diabres.2023.110736_b0015","unstructured":"Graham D Ogle FW, Gabriel A Gregory and Jayanthi Maniam International Diabetes Federation Atlas Report 2022. Type 1 dibaetes estimates in children and adults. 2022."},{"issue":"8","key":"10.1016\/j.diabres.2023.110736_b0020","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1111\/pedi.12769","article-title":"Health-related quality of life of adolescents with type 1 diabetes in the context of resilience","volume":"19","author":"Luk\u00e1cs","year":"2018","journal-title":"Pediatr Diabetes"},{"key":"10.1016\/j.diabres.2023.110736_b0025","doi-asserted-by":"crossref","first-page":"370","DOI":"10.3389\/fendo.2020.00370","article-title":"Vascular complication in adolescents with diabetes mellitus","volume":"11","author":"Graves","year":"2020","journal-title":"Front Endocrinol"},{"issue":"1","key":"10.1016\/j.diabres.2023.110736_b0030","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3233\/JAD-161250","article-title":"Type 1 diabetes mellitus and cognitive impairments: A systematic review","volume":"57","author":"Li","year":"2017","journal-title":"J Alzheimers Dis"},{"issue":"4","key":"10.1016\/j.diabres.2023.110736_b0035","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.2337\/dc19-2394","article-title":"Burden of complications in U.S. adults with young-onset type 2 or Type 1 diabetes","volume":"43","author":"Fang","year":"2020","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2023.110736_b0040","article-title":"Large fibre, small fibre and autonomic neuropathy in adolescents with type 1 diabetes: A systematic review","volume":"108027","author":"Rasmussen","year":"2021","journal-title":"J Diabetes Complications"},{"issue":"3","key":"10.1016\/j.diabres.2023.110736_b0045","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s00592-022-01850-x","article-title":"A systematic review of the prevalence, risk factors and screening tools for autonomic and diabetic peripheral neuropathy in children, adolescents and young adults with type 1 diabetes","volume":"59","author":"Franceschi","year":"2022","journal-title":"Acta Diabetol"},{"issue":"1","key":"10.1016\/j.diabres.2023.110736_b0050","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/BF02581357","article-title":"Peripheral nerve abnormalities in newly-diagnosed diabetic children","volume":"23","author":"Comi","year":"1986","journal-title":"Acta Diabetol Lat"},{"key":"10.1016\/j.diabres.2023.110736_b0055","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.pediatrneurol.2017.11.017","article-title":"High prevalence and incidence of diabetic peripheral neuropathy in children and adolescents with type 1 diabetes mellitus: Results from a five-year prospective cohort study","volume":"80","author":"Walter-H\u00f6liner","year":"2018","journal-title":"Pediatr Neurol"},{"issue":"10","key":"10.1016\/j.diabres.2023.110736_b0060","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.2337\/dc10-1303","article-title":"Diabetic neuropathies: Update on definitions, diagnostic criteria, estimation of severity, and treatments","volume":"33","author":"Tesfaye","year":"2010","journal-title":"Diabetes Care"},{"issue":"2","key":"10.1016\/j.diabres.2023.110736_b0065","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.clinph.2020.11.024","article-title":"Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the american autonomic society, american academy of neurology, and the international federation of clinical neurophysiology","volume":"132","author":"Cheshire","year":"2021","journal-title":"Clin Neurophysiol"},{"issue":"5","key":"10.1016\/j.diabres.2023.110736_b0070","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.2337\/dc20-2387","article-title":"Risk factors for longitudinal resting heart rate and its associations with cardiovascular outcomes in the DCCT\/EDIC Study","volume":"44","author":"Keshavarzi","year":"2021","journal-title":"Diabetes Care"},{"issue":"7","key":"10.1016\/j.diabres.2023.110736_b0075","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.2337\/dc08-0107","article-title":"Relationship between risk factors and mortality in type 1 diabetic patients in Europe: The EURODIAB Prospective Complications Study (PCS)","volume":"31","author":"Soedamah-Muthu","year":"2008","journal-title":"Diabetes Care"},{"issue":"Suppl 27","key":"10.1016\/j.diabres.2023.110736_b0080","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/pedi.12742","article-title":"ISPAD Clinical Practice Consensus Guidelines 2018: Microvascular and macrovascular complications in children and adolescents","volume":"19","author":"Donaghue","year":"2018","journal-title":"Pediatr Diabetes"},{"issue":"9","key":"10.1016\/j.diabres.2023.110736_b0085","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1016\/j.clinph.2017.06.031","article-title":"Diagnostic utility of distal nerve conduction studies and sural near-nerve needle recording in polyneuropathy","volume":"128","author":"Kural","year":"2017","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.diabres.2023.110736_b0090","first-page":"214","article-title":"Evidence-based recommendations for examination and diagnostic strategies of polyneuropathy electrodiagnosis","volume":"4","author":"Tankisi","year":"2019","journal-title":"Clin Neurophysiol"},{"issue":"3","key":"10.1016\/j.diabres.2023.110736_b0095","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1097\/NEN.0b013e318284e849","article-title":"Epidermal Nerve Fiber Length Density Estimation Using Global Spatial Sampling in Healthy Subjects and Neuropathy Patients","volume":"72","author":"Karlsson","year":"2013","journal-title":"J Neuropathol Exp Neurol"},{"issue":"2","key":"10.1016\/j.diabres.2023.110736_b0100","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10286-008-0506-8","article-title":"Sweat testing to evaluate autonomic function","volume":"19","author":"Illigens","year":"2009","journal-title":"Clin Auton Res"},{"issue":"2","key":"10.1016\/j.diabres.2023.110736_b0105","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s10286-011-0119-5","article-title":"Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome","volume":"21","author":"Freeman","year":"2011","journal-title":"Clin Autonomic Res: Off J Clin Autonomic Res Soc"},{"key":"10.1016\/j.diabres.2023.110736_b0110","unstructured":"NeuroMetrix. Sural Nerve Conduction Interpretation Guide. http:\/\/www.dpncheck.com\/wp-content\/uploads\/2017\/08\/nc-stat_dpncheck_sural_nerve_conduction_guide_pn2203523_rev_d.pdf. Published 2012. Accessed."},{"issue":"5","key":"10.1016\/j.diabres.2023.110736_b0115","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1111\/jdi.13007","article-title":"Validity and reliability of a point-of-care nerve conduction device in diabetes patients","volume":"10","author":"Shibata","year":"2019","journal-title":"J Diabetes Investig"},{"issue":"11","key":"10.1016\/j.diabres.2023.110736_b0120","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1089\/dia.2013.0129","article-title":"Sudoscan, a noninvasive tool for detecting diabetic small fiber neuropathy and autonomic dysfunction","volume":"15","author":"Casellini","year":"2013","journal-title":"Diabetes Technol Ther"},{"issue":"4","key":"10.1016\/j.diabres.2023.110736_b0125","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1177\/193229681200600430","article-title":"Screening for diabetic cardiac autonomic neuropathy using a new handheld device","volume":"6","author":"Gulichsen","year":"2012","journal-title":"J Diabetes Sci Technol"},{"issue":"3","key":"10.1016\/j.diabres.2023.110736_b0130","article-title":"Translation and linguistic validation of the Composite Autonomic Symptom Score COMPASS 31 in Danish","volume":"69","author":"Brinth","year":"2021","journal-title":"Dan Med J"},{"issue":"3","key":"10.1016\/j.diabres.2023.110736_b0135","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1529-8027.2008.00180.x","article-title":"The Utah Early Neuropathy Scale: a sensitive clinical scale for early sensory predominant neuropathy","volume":"13","author":"Singleton","year":"2008","journal-title":"J Peripher Nerv Syst"},{"issue":"2","key":"10.1016\/j.diabres.2023.110736_b0140","doi-asserted-by":"crossref","first-page":"e002480","DOI":"10.1136\/bmjdrc-2021-002480","article-title":"Cardiac autonomic neuropathy and risk of cardiovascular disease and mortality in type 1 and type 2 diabetes: a meta-analysis","volume":"9","author":"Chowdhury","year":"2021","journal-title":"BMJ Open Diabetes Res Care"},{"issue":"11","key":"10.1016\/j.diabres.2023.110736_b0145","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1111\/j.1464-5491.2012.03685.x","article-title":"Childhood diabetic neuropathy: functional impairment and non-invasive screening assessment","volume":"29","author":"Blankenburg","year":"2012","journal-title":"Diabet Med"},{"issue":"3","key":"10.1016\/j.diabres.2023.110736_b0150","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.pediatrneurol.2013.03.014","article-title":"Validity of the neurological examination in diagnosing diabetic peripheral neuropathy","volume":"49","author":"H\u00f6liner","year":"2013","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.diabres.2023.110736_b0155","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.diabres.2016.04.044","article-title":"The prevalence of early subclinical somatic neuropathy in children and adolescents with Type 1 diabetes mellitus and its association with the persistence of autoantibodies to glutamic acid decarboxylase (GAD) and islet antigen-2 (IA-2)","volume":"117","author":"Louraki","year":"2016","journal-title":"Diabetes Res Clin Pract"},{"issue":"6","key":"10.1016\/j.diabres.2023.110736_b0160","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1399-5448.2006.00208.x","article-title":"Comparison of conventional and non-invasive techniques for the early identification of diabetic neuropathy in children and adolescents with type 1 diabetes","volume":"7","author":"Nelson","year":"2006","journal-title":"Pediatr Diabetes"},{"key":"10.1016\/j.diabres.2023.110736_b0165","series-title":"Diabetic Neuropathy","first-page":"79","article-title":"Chapter 5 - Skin biopsy analysis in diabetic neuropathy","author":"Karlsson","year":"2022"},{"issue":"7\u20138","key":"10.1016\/j.diabres.2023.110736_b0170","first-page":"709","article-title":"Exhaled carbon monoxide in adolescents with diabetic cardiovascular autonomic neuropathy","volume":"27","author":"Vojtkov\u00e1","year":"2014","journal-title":"J Pediatr Endocrinol Metab"},{"issue":"1","key":"10.1016\/j.diabres.2023.110736_b0175","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jdiacomp.2015.10.011","article-title":"Pulmonary function tests in type 1 diabetes adolescents with diabetic cardiovascular autonomic neuropathy","volume":"30","author":"\u010eurd\u00edk","year":"2016","journal-title":"J Diabetes Complications"},{"issue":"8","key":"10.1016\/j.diabres.2023.110736_b0180","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1001\/jama.2017.0686","article-title":"Association of Type 1 Diabetes vs Type 2 Diabetes Diagnosed During Childhood and Adolescence With Complications During Teenage Years and Young Adulthood","volume":"317","author":"Dabelea","year":"2017","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.diabres.2023.110736_b0185","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/jdi.13635","article-title":"Utility of using electrocardiogram measures of heart rate variability as a measure of cardiovascular autonomic neuropathy in type 1 diabetes patients","volume":"13","author":"Pop-Busui","year":"2022","journal-title":"J Diabetes Investig"},{"issue":"8","key":"10.1016\/j.diabres.2023.110736_b0190","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/S0025-6196(12)60631-4","article-title":"Composite autonomic scoring scale for laboratory quantification of generalized autonomic failure","volume":"68","author":"Low","year":"1993","journal-title":"Mayo Clin Proc"},{"issue":"2","key":"10.1016\/j.diabres.2023.110736_b0195","doi-asserted-by":"crossref","first-page":"e0212574","DOI":"10.1371\/journal.pone.0212574","article-title":"The risk factors for diabetic peripheral neuropathy: A meta-analysis","volume":"14","author":"Liu","year":"2019","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.diabres.2023.110736_b0200","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/pedi.12382","article-title":"A 10-yr follow-up study for the detection of peripheral neuropathy in young patients with type 1 diabetes","volume":"17","author":"Hajas","year":"2016","journal-title":"Pediatr Diabetes"},{"key":"10.1016\/j.diabres.2023.110736_b0205","doi-asserted-by":"crossref","unstructured":"Martin CL, Albers JW, Pop-Busui R, Group DER. Neuropathy and related findings in the diabetes control and complications trial\/epidemiology of diabetes interventions and complications study. Diabetes care. 2014;37(1):31-38.","DOI":"10.2337\/dc13-2114"},{"key":"10.1016\/j.diabres.2023.110736_b0210","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3389\/fnins.2016.00581","article-title":"A Role for Insulin in Diabetic Neuropathy","volume":"10","author":"Grote","year":"2016","journal-title":"Front Neurosci"}],"updated-by":[{"DOI":"10.1016\/j.diabres.2023.110950","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000}}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822723004990?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822723004990?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:26:49Z","timestamp":1686875209000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822723004990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":42,"alternative-id":["S0168822723004990"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2023.110736","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.diabres.2023.110950","asserted-by":"object"}]},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neuropathy in adolescents with type 1 diabetes: Confirmatory diagnostic tests, bedside tests, and risk factors","name":"articletitle","label":"Article Title"},{"value":"Diabetes Research and Clinical Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diabres.2023.110736","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110736"}}