{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T08:50:09Z","timestamp":1781340609113,"version":"3.54.1"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T00:00:00Z","timestamp":1712102400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","diabetesresearchclinicalpractice.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.diabres.2024.111644","type":"journal-article","created":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T08:19:43Z","timestamp":1711527583000},"page":"111644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Frequency of brain ventricular enlargement among patients with diabetes mellitus"],"prefix":"10.1016","volume":"210","author":[{"given":"Antonio","family":"Curr\u00e0","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4739-1582","authenticated-orcid":false,"given":"Riccardo","family":"Gasbarrone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Gargiulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1863-8251","authenticated-orcid":false,"given":"Aurelia","family":"Rughetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Peschillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Trompetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Puce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0620-7654","authenticated-orcid":false,"given":"Lucio","family":"Marinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fattapposta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola Luigi","family":"Bragazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2056-0104","authenticated-orcid":false,"given":"Paolo","family":"Missori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabres.2024.111644_b0005","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1136\/jnnp.40.4.331","article-title":"Diabetes mellitus in normal pressure hydrocephalus","volume":"40","author":"Jacobs","year":"1977","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.diabres.2024.111644_b0010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1159\/000026235","article-title":"Clinical correlates of ventricular and sulcal size on cranial magnetic resonance imaging of 3,301 elderly people: The cardiovascular health study","volume":"19","author":"Longstreth","year":"2000","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.diabres.2024.111644_b0015","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1136\/jnnp.52.7.847","article-title":"Risk factors for the syndrome of ventricular enlargement with gait apraxia (idiopathic normal pressure hydrocephalus): a case-control study","volume":"52","author":"Casmiro","year":"1989","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.diabres.2024.111644_b0020","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1161\/01.STR.27.1.24","article-title":"Vascular risk factors and arteriosclerotic disease in idiopathic normal-pressure hydrocephalus of the elderly","volume":"27","author":"Krauss","year":"1996","journal-title":"Stroke"},{"key":"10.1016\/j.diabres.2024.111644_b0025","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1007\/s00415-008-0928-1","article-title":"Shunt-responsive parkinsonism and reversible white matter lesions in patients with idiopathic NPH","volume":"255","author":"Akiguchi","year":"2008","journal-title":"J Neurol"},{"key":"10.1016\/j.diabres.2024.111644_b0030","doi-asserted-by":"crossref","DOI":"10.1186\/2045-8118-11-19","article-title":"Increased prevalence of cardiovascular disease in idiopathic normal pressure hydrocephalus patients compared to a population-based cohort from the HUNT3 survey","volume":"11","author":"Eide","year":"2014","journal-title":"Fluids Barriers CNS."},{"key":"10.1016\/j.diabres.2024.111644_b0035","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.635","article-title":"Nationwide hospital-based survey of idiopathic normal pressure hydrocephalus in Japan: Epidemiological and clinical characteristics","volume":"7","author":"Kuriyama","year":"2017","journal-title":"Brain Behav"},{"key":"10.1016\/j.diabres.2024.111644_b0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12987-019-0125-x","article-title":"Comorbidity of diabetes mellitus in idiopathic normal pressure hydrocephalus: a systematic literature review","volume":"16","author":"Hudson","year":"2019","journal-title":"Fluids Barriers CNS"},{"key":"10.1016\/j.diabres.2024.111644_b0045","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1210\/endo-23-2-175","article-title":"Adiposity and diabetes mellitus in a monkey with hypothalamic lesions","volume":"23","author":"Ranson","year":"1938","journal-title":"Endocrinology"},{"key":"10.1016\/j.diabres.2024.111644_b0050","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1046\/j.1464-5491.1999.00067.x","article-title":"Hypothalamic arousal, insulin resistance and type 2 diabetes mellitus","volume":"16","author":"Bj\u00f6rntorp","year":"1999","journal-title":"Diabet Med"},{"key":"10.1016\/j.diabres.2024.111644_b0055","doi-asserted-by":"crossref","first-page":"11860","DOI":"10.18632\/oncotarget.7644","article-title":"In normal aging ventricular system never attains pathological values of Evans' index","volume":"7","author":"Missori","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.diabres.2024.111644_b0060","doi-asserted-by":"crossref","first-page":"294","DOI":"10.3389\/fnagi.2019.00294","article-title":"The ventricular system enlarges abnormally in the seventies, earlier in men, and first in the frontal horn: a study based on more than 3,000 scans","volume":"11","author":"Curr\u00e0","year":"2019","journal-title":"Front Aging Neurosci"},{"key":"10.1016\/j.diabres.2024.111644_b0065","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1227\/01.NEU.0000370939.30003.D1","article-title":"Brain ventricular size in healthy elderly: comparison between Evans index and volume measurement","volume":"67","author":"Ambarki","year":"2010","journal-title":"Neurosurgery"},{"key":"10.1016\/j.diabres.2024.111644_b0070","first-page":"8","article-title":"Clinical burden of diabetes in Italy in 2018: a look at a systemic disease from the ARNO Diabetes Observatory","author":"Bonora","year":"2020","journal-title":"BMJ Open Diabetes Res Care"},{"key":"10.1016\/j.diabres.2024.111644_b0075","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.13867","article-title":"Trends and variations in emergency department use associated with diabetes in the US by sociodemographic factors, 2008\u20132017","volume":"5","author":"Uppal","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.diabres.2024.111644_b0080","doi-asserted-by":"crossref","unstructured":"Relkin N, Marmarou A, Klinge P, Bergsneider M, Black PM. Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery. 2005;57:S4-16; discussion ii-v.","DOI":"10.1227\/01.NEU.0000168185.29659.C5"},{"key":"10.1016\/j.diabres.2024.111644_b0085","doi-asserted-by":"crossref","first-page":"687","DOI":"10.2337\/diabetes.53.3.687","article-title":"Magnetic resonance imaging of the brain in diabetes: the Cardiovascular Determinants of Dementia (CASCADE) Study","volume":"53","author":"Schmidt","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.diabres.2024.111644_b0090","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.2337\/dc06-1637","article-title":"Brain imaging in patients with diabetes: a systematic review","volume":"29","author":"van Harten","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1016\/j.diabres.2024.111644_b0095","article-title":"Morphometric changes in lateral ventricles of patients with recent-onset type 2 diabetes mellitus","volume":"8","author":"Lee","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.diabres.2024.111644_b0100","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20211275","article-title":"Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration","volume":"219","author":"Ishida","year":"2022","journal-title":"J Exp Med"},{"key":"10.1016\/j.diabres.2024.111644_b0105","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1177\/0271678X16654702","article-title":"Impairment of the glymphatic system after diabetes","volume":"37","author":"Jiang","year":"2017","journal-title":"J Cereb Blood Flow Metab"},{"key":"10.1016\/j.diabres.2024.111644_b0110","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1136\/svn-2018-000203","article-title":"Role of the glymphatic system in ageing and diabetes mellitus impaired cognitive function","volume":"4","author":"Zhang","year":"2019","journal-title":"Stroke Vasc Neurol."},{"key":"10.1016\/j.diabres.2024.111644_b0115","doi-asserted-by":"crossref","first-page":"300","DOI":"10.3389\/fnhum.2020.00300","article-title":"Evaluation of glymphatic system using diffusion MR technique in T2DM cases","volume":"14","author":"Yang","year":"2020","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.diabres.2024.111644_b0120","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1042\/CS20150586","article-title":"Women and heart disease, the underrecognized burden: sex differences, biases, and unmet clinical and research challenges","volume":"130","author":"Westerman","year":"2016","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.diabres.2024.111644_b0125","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/YCO.0000000000000401","article-title":"Sex differences in Alzheimer's disease","volume":"31","author":"Laws","year":"2018","journal-title":"Curr Opin Psychiatry"},{"key":"10.1016\/j.diabres.2024.111644_b0130","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.parkreldis.2021.06.004","article-title":"Diffusion along perivascular spaces reveals evidence supportive of glymphatic function impairment in Parkinson disease","volume":"89","author":"McKnight","year":"2021","journal-title":"Parkinsonism Relat Disord"},{"key":"10.1016\/j.diabres.2024.111644_b0135","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1007\/s12031-018-1038-x","article-title":"Endogenous sex steroids dampen neuroinflammation and improve outcome of traumatic brain injury in mice","volume":"64","author":"Clevenger","year":"2018","journal-title":"J Mol Neurosci"},{"key":"10.1016\/j.diabres.2024.111644_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108524","article-title":"Direct measurement of cerebrospinal fluid production in mice","volume":"33","author":"Liu","year":"2020","journal-title":"Cell Rep"},{"key":"10.1016\/j.diabres.2024.111644_b0145","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-72621-3","article-title":"Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice","volume":"10","author":"Giannetto","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.diabres.2024.111644_b0150","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0168-8227(99)00117-5","article-title":"Normal pressure hydrocephalus in diabetic patients with recurrent episodes of hypoglycemic coma","volume":"47","author":"Iino","year":"2000","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.diabres.2024.111644_b0155","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.tins.2013.07.001","article-title":"Sugar for the brain: the role of glucose in physiological and pathological brain function","volume":"36","author":"Mergenthaler","year":"2013","journal-title":"Trends Neurosci"}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822724001347?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822724001347?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T06:44:45Z","timestamp":1731393885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822724001347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":31,"alternative-id":["S0168822724001347"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2024.111644","relation":{},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frequency of brain ventricular enlargement among patients with diabetes mellitus","name":"articletitle","label":"Article Title"},{"value":"Diabetes Research and Clinical Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diabres.2024.111644","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"111644"}}