{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T09:26:21Z","timestamp":1788600381052,"version":"build-2803163510"},"reference-count":74,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","diabetesresearchclinicalpractice.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Research and Clinical Practice"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.diabres.2026.113102","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T16:21:17Z","timestamp":1768234877000},"page":"113102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Therapeutic potential of prebiotics in modulating postprandial GLP-1, GLP-2, and glucose homeostasis in type 2 diabetes mellitus: Targeting gut dysbiosis and insulin resistance"],"prefix":"10.1016","volume":"232","author":[{"given":"Zainab","family":"Irfan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitu","family":"Halder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6514-334X","authenticated-orcid":false,"given":"Sumon","family":"Giri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekbal Ali","family":"Molla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Khanam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diabres.2026.113102_b0005","doi-asserted-by":"crossref","first-page":"210","DOI":"10.37022\/wjcmpr.v5i5.294","article-title":"Profiling of clinical dynamics of type 2 diabetes mellitus in patients: a perspective review","author":"Ikwuka","year":"2023","journal-title":"World J Curr Med Pharm Res"},{"key":"10.1016\/j.diabres.2026.113102_b0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1243834","article-title":"Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review","volume":"14","author":"Su","year":"2023","journal-title":"Front Immunol"},{"key":"10.1016\/j.diabres.2026.113102_b0015","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.768850","article-title":"Efficacy of sodium-glucose cotransporter 2 inhibitors in patients with concurrent type 2 diabetes mellitus and non-alcoholic steatohepatitis: a review of the evidence","volume":"12","author":"Yabiku","year":"2021","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.diabres.2026.113102_b0020","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2024.1395664","article-title":"Unveiling the dynamics of gut microbial interactions: a review of dietary impact and precision nutrition in gastrointestinal health","volume":"11","author":"Shang","year":"2024","journal-title":"Front Nutr"},{"issue":"11","key":"10.1016\/j.diabres.2026.113102_b0025","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1136\/gutjnl-2024-333378","article-title":"What defines a healthy gut microbiome?","volume":"73","author":"Van Hul","year":"2024","journal-title":"Gut"},{"key":"10.1016\/j.diabres.2026.113102_b0030","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1480811","article-title":"The microbiota: a key regulator of mammals' health, productivity, and reproductive success","volume":"15","author":"Khan","year":"2024","journal-title":"Front Microbiol"},{"issue":"8","key":"10.1016\/j.diabres.2026.113102_b0035","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3390\/diabetology6080079","article-title":"Exploring the epidemiologic burden, pathogenetic features, and clinical outcomes of primary liver cancer in patients with type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated steatotic liver disease (MASLD): a scoping review","volume":"6","author":"Romeo","year":"2025","journal-title":"Diabetol"},{"key":"10.1016\/j.diabres.2026.113102_b0040","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.943427","article-title":"Gut microbiota composition in prediabetes and newly diagnosed type 2 diabetes: a systematic review of observational studies","volume":"12","author":"Letchumanan","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.diabres.2026.113102_b0045","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1146\/annurev-med-042220-012821","article-title":"The gut microbiome: connecting diet, glucose homeostasis, and disease","volume":"73","author":"Howard","year":"2022","journal-title":"Annu Rev Med"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0050","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.3390\/microorganisms8101587","article-title":"Gut microbiota and immune system interactions","volume":"8","author":"Yoo","year":"2020","journal-title":"Microorg"},{"issue":"2","key":"10.1016\/j.diabres.2026.113102_b0055","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00592-021-01790-y","article-title":"Gut microbiota dysbiosis of type 2 diabetic mice impairs the intestinal daily rhythms of GLP-1 sensitivity","volume":"59","author":"Grasset","year":"2022","journal-title":"Acta Diabetol"},{"key":"10.1016\/j.diabres.2026.113102_b0060","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.721135","article-title":"GLP-1 receptor agonists: beyond their pancreatic effects","volume":"12","author":"Zhao","year":"2021","journal-title":"Front Endocrinol"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0065","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.3390\/microorganisms10102061","article-title":"GLP-1 and GLP-2 orchestrate intestine integrity, gut microbiota, and immune system crosstalk","volume":"10","author":"Abdalqadir","year":"2022","journal-title":"Microorg"},{"issue":"11","key":"10.1016\/j.diabres.2026.113102_b0070","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.3390\/ph15111329","article-title":"The therapeutic potential of plant polysaccharides in metabolic diseases","volume":"15","author":"Wang","year":"2022","journal-title":"Pharmaceuticals"},{"issue":"4","key":"10.1016\/j.diabres.2026.113102_b0075","first-page":"1037","article-title":"Mechanisms of action of prebiotics and their effects on gastro-intestinal disorders in adults","volume":"12","author":"Guarino","year":"2020","journal-title":"Nutr"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0080","doi-asserted-by":"crossref","DOI":"10.1111\/dme.14657","article-title":"Effects of prebiotics on postprandial GLP\u20101, GLP\u20102 and glucose regulation in patients with type 2 diabetes: a randomised, double\u2010blind, placebo\u2010controlled crossover trial","volume":"38","author":"Birkeland","year":"2021","journal-title":"Diabet Med"},{"issue":"4","key":"10.1016\/j.diabres.2026.113102_b0085","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1016\/j.clnu.2020.10.032","article-title":"Effects of soluble fiber supplementation on glycemic control in adults with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials","volume":"40","author":"Xie","year":"2021","journal-title":"Clin Nutr"},{"issue":"17","key":"10.1016\/j.diabres.2026.113102_b0090","doi-asserted-by":"crossref","first-page":"8644","DOI":"10.1039\/D4FO01059K","article-title":"Improving insulin resistance by sulforaphane via activating the Bacteroides and Lactobacillus SCFAs\u2013GPR\u2013GLP1 signal axis","volume":"15","author":"Tian","year":"2024","journal-title":"Food Funct"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0095","first-page":"1","article-title":"Type 2 diabetes mellitus and the gut microbiota: charting new territory for sodium-glucose co-transporter 2 inhibitors","volume":"8","author":"Stepanova","year":"2024","journal-title":"Eurasian J. Med. Oncol."},{"issue":"5","key":"10.1016\/j.diabres.2026.113102_b0100","doi-asserted-by":"crossref","first-page":"793","DOI":"10.3390\/cells12050793","article-title":"Gut-microbiota-derived metabolites maintain gut and systemic immune homeostasis","volume":"12","author":"Wang","year":"2023","journal-title":"Cells"},{"issue":"9","key":"10.1016\/j.diabres.2026.113102_b0105","first-page":"1307","article-title":"Prebiotics progress shifts in the intestinal microbiome that benefits patients with type 2 diabetes mellitus","volume":"13","author":"Vitetta","year":"2023","journal-title":"Biomol"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0110","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.3390\/ijms20102432","article-title":"Dysbiosis disrupts gut immune homeostasis and promotes gastric diseases","volume":"20","author":"Toor","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.diabres.2026.113102_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2022.106312","article-title":"Fecal 16S rRNA sequencing and multi-compartment metabolomics revealed gut microbiota and metabolites interactions in APP\/PS1 mice","volume":"151","author":"Cheng","year":"2022","journal-title":"Comput Biol Med"},{"issue":"12","key":"10.1016\/j.diabres.2026.113102_b0120","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0243077","article-title":"Gut mycobiomes are altered in people with type 2 diabetes mellitus and diabetic retinopathy","volume":"15","author":"Jayasudha","year":"2020","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.diabres.2026.113102_b0125","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/advances\/nmy084","article-title":"Glutamine metabolism in macrophages: a novel target for obesity\/type 2 diabetes","volume":"10","author":"Ren","year":"2019","journal-title":"Adv Nutr"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0130","doi-asserted-by":"crossref","first-page":"480","DOI":"10.3390\/ijms23010480","article-title":"The role of the gut microbiota in the pathogenesis of diabetes","volume":"23","author":"Bielka","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.diabres.2026.113102_b0135","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11739-023-03374-w","article-title":"Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review","volume":"19","author":"Di Vincenzo","year":"2024","journal-title":"Intern Emerg Med"},{"issue":"7","key":"10.1016\/j.diabres.2026.113102_b0140","doi-asserted-by":"crossref","first-page":"3566","DOI":"10.3390\/ijms22073566","article-title":"The relationship between the gut microbiome and metformin as a key for treating type 2 diabetes mellitus","volume":"22","author":"Lee","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0145","first-page":"8","article-title":"The gut microbiome and type 2 diabetes mellitus: discussing a complex relationship","volume":"8","author":"Sikalidis","year":"2020","journal-title":"Biomed"},{"issue":"6","key":"10.1016\/j.diabres.2026.113102_b0150","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1002\/hep.32235","article-title":"A GLP\u20101\/GLP\u20102 receptor dual agonist to treat NASH: targeting the gut\u2010liver axis and microbiome","volume":"75","author":"Kim","year":"2022","journal-title":"Hepatol"},{"key":"10.1016\/j.diabres.2026.113102_b0155","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.901559","article-title":"Effects of GLP-1 receptor agonists on biological behavior of colorectal cancer cells by regulating PI3K\/AKT\/mTOR signaling pathway","volume":"13","author":"Tong","year":"2022","journal-title":"Front Pharmacol"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0160","article-title":"Expression profile of the GLP-1 receptor in the gastrointestinal tract and pancreas in adult female mice","volume":"163","author":"Grunddal","year":"2022","journal-title":"Endocrinol"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0165","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.2337\/db14-0100","article-title":"GLP-1 secretion is increased by inflammatory stimuli in an IL-6\u2013dependent manner, leading to hyperinsulinemia and blood glucose lowering","volume":"63","author":"Kahles","year":"2014","journal-title":"Diabet"},{"key":"10.1016\/j.diabres.2026.113102_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107845","article-title":"The role of incretins and incretin-based drugs in autoimmune diseases","volume":"98","author":"Radbakhsh","year":"2021","journal-title":"Int Immunopharmacol"},{"issue":"9","key":"10.1016\/j.diabres.2026.113102_b0175","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1007\/s00125-017-4315-2","article-title":"The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice","volume":"60","author":"\u00d8rgaard","year":"2017","journal-title":"Diabetol"},{"issue":"22","key":"10.1016\/j.diabres.2026.113102_b0180","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1056\/NEJMoa1916038","article-title":"A randomized, controlled trial of liraglutide for adolescents with obesity","volume":"382","author":"Kelly","year":"2020","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0185","doi-asserted-by":"crossref","first-page":"3538","DOI":"10.1210\/EN.2015-1110","article-title":"Glucagon-like peptide 2 (GLP-2) stimulates postprandial chylomicron production and postabsorptive release of intestinal triglyceride storage pools via induction of nitric oxide signaling in male hamsters and mice","volume":"156","author":"Hsieh","year":"2015","journal-title":"Endocrinol"},{"issue":"6","key":"10.1016\/j.diabres.2026.113102_b0190","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1053\/j.gastro.2014.08.037","article-title":"Glucagon-like peptide-2 regulates release of chylomicrons from the intestine","volume":"147","author":"Dash","year":"2014","journal-title":"Gastroenterol"},{"issue":"3","key":"10.1016\/j.diabres.2026.113102_b0195","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3390\/ijms23031105","article-title":"Gut microbiota and short chain fatty acids: implications in glucose homeostasis","volume":"23","author":"Portincasa","year":"2022","journal-title":"Int J Mol Sci"},{"issue":"11","key":"10.1016\/j.diabres.2026.113102_b0200","first-page":"719","article-title":"The gut\u2013liver axis and gut microbiota in health and liver disease","volume":"21","author":"Hsu","year":"2023","journal-title":"Nat RevMicrobiol"},{"issue":"7978","key":"10.1016\/j.diabres.2026.113102_b0205","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/s41586-023-06466-x","article-title":"Gut microbial carbohydrate metabolism contributes to insulin resistance","volume":"621","author":"Takeuchi","year":"2023","journal-title":"Nat"},{"issue":"9","key":"10.1016\/j.diabres.2026.113102_b0210","first-page":"2211","article-title":"Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota","volume":"15","author":"Fusco","year":"2023","journal-title":"Nutr"},{"issue":"5","key":"10.1016\/j.diabres.2026.113102_b0215","first-page":"261","article-title":"Gut microbial metabolites in obesity, NAFLD and T2DM","volume":"15","author":"Canfora","year":"2019","journal-title":"Nat RevEndocrinol"},{"issue":"2","key":"10.1016\/j.diabres.2026.113102_b0220","doi-asserted-by":"crossref","first-page":"364","DOI":"10.2337\/db11-1019","article-title":"Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein\u2013coupled receptor FFAR2","volume":"61","author":"Tolhurst","year":"2012","journal-title":"Diabet"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0225","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41579-020-0433-9","article-title":"Gut microbiota in human metabolic health and disease","volume":"19","author":"Fan","year":"2021","journal-title":"Nat Rev Microbiol"},{"issue":"4","key":"10.1016\/j.diabres.2026.113102_b0230","doi-asserted-by":"crossref","first-page":"995","DOI":"10.3390\/ijms19040995","article-title":"Gut microbiota and type 1 diabetes","volume":"19","author":"Han","year":"2018","journal-title":"Int J Mol Sci"},{"issue":"5","key":"10.1016\/j.diabres.2026.113102_b0235","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3920\/BM2020.0057","article-title":"Short chain fatty acids in human gut and metabolic health","volume":"11","author":"Blaak","year":"2020","journal-title":"Benef Microbe"},{"key":"10.1016\/j.diabres.2026.113102_b0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2019.11.051","article-title":"Role of gut microbiota in type 2 diabetes pathophysiology","volume":"51","author":"Gurung","year":"2020","journal-title":"EBioMedicine"},{"issue":"9","key":"10.1016\/j.diabres.2026.113102_b0245","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1136\/gutjnl-2014-306928","article-title":"Microbiota and diabetes: an evolving relationship","volume":"63","author":"Tilg","year":"2014","journal-title":"Gut"},{"issue":"4","key":"10.1016\/j.diabres.2026.113102_b0250","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3390\/jcm8040452","article-title":"Faecal microbiota are related to insulin sensitivity and secretion in overweight or obese adults","volume":"8","author":"Naderpoor","year":"2019","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0255","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s40814-023-01373-4","article-title":"Evaluating the effect of prebiotics on the gut microbiome profile and \u03b2 cell function in youth with newly diagnosed type 1 diabetes: protocol of a pilot randomized controlled trial","volume":"9","author":"Ismail","year":"2023","journal-title":"Pilot Feasibility Stud"},{"issue":"11","key":"10.1016\/j.diabres.2026.113102_b0260","article-title":"Effects of healthy low-carbohydrate diet and time-restricted eating on weight and gut microbiome in adults with overweight or obesity: feeding RCT","volume":"5","author":"Li","year":"2024","journal-title":"Cell Rep Med"},{"issue":"5","key":"10.1016\/j.diabres.2026.113102_b0265","first-page":"1655","article-title":"Dietary fibre modulates the gut microbiota","volume":"13","author":"Cronin","year":"2021","journal-title":"Nutr"},{"issue":"6380","key":"10.1016\/j.diabres.2026.113102_b0270","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1126\/science.aao5774","article-title":"Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes","volume":"359","author":"Zhao","year":"2018","journal-title":"Sci"},{"key":"10.1016\/j.diabres.2026.113102_b0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110415","article-title":"A prebiotic fructo-oligosaccharide promotes tight junction assembly in intestinal epithelial cells via an AMPK-dependent pathway","volume":"129","author":"Wongkrasant","year":"2020","journal-title":"Biomed Pharmacother"},{"issue":"16","key":"10.1016\/j.diabres.2026.113102_b0280","first-page":"3369","article-title":"Insoluble and soluble dietary fibers from kiwifruit (Actinidia deliciosa) modify gut microbiota to alleviate high-fat diet and streptozotocin-induced TYPE 2 diabetes in rats","volume":"14","author":"Wang","year":"2022","journal-title":"Nutr"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0285","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s11010-013-1911-4","article-title":"Increased circulatory levels of lipopolysaccharide (LPS) and zonulin signify novel biomarkers of proinflammation in patients with type 2 diabetes","volume":"388","author":"Jayashree","year":"2014","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.diabres.2026.113102_b0290","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.652942","article-title":"Impact of sodium butyrate treatment in LPS-stimulated peripheral blood mononuclear cells of poorly controlled type 2 DM","volume":"12","author":"Wibowo","year":"2021","journal-title":"Front Endocrinol"},{"issue":"31","key":"10.1016\/j.diabres.2026.113102_b0295","doi-asserted-by":"crossref","first-page":"11929","DOI":"10.1021\/acs.jafc.3c02429","article-title":"Dendrobium officinale polysaccharide alleviates type 2 diabetes mellitus by restoring gut microbiota and repairing intestinal barrier via the LPS\/TLR4\/TRIF\/NF-kB Axis","volume":"71","author":"Chen","year":"2023","journal-title":"J Agric Food Chem"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0300","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1038\/s41598-017-02546-x","article-title":"Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight\/obese men: a randomized crossover trial","volume":"7","author":"Canfora","year":"2017","journal-title":"Sci Rep"},{"issue":"11","key":"10.1016\/j.diabres.2026.113102_b0305","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1136\/gutjnl-2014-307913","article-title":"Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults","volume":"64","author":"Chambers","year":"2015","journal-title":"Gut"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0310","first-page":"2383","article-title":"Acute effects of dietary fiber in starchy foods on glycemic and insulinemic responses: a systematic review of randomized controlled crossover trials","volume":"15","author":"Tsitsou","year":"2023","journal-title":"Nutr"},{"issue":"11","key":"10.1016\/j.diabres.2026.113102_b0315","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1038\/s41430-021-00875-9","article-title":"The effect of oat \u03b2-glucan on postprandial blood glucose and insulin responses: a systematic review and meta-analysis","volume":"75","author":"Zurbau","year":"2021","journal-title":"Eur J Clin Nutr"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0320","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1186\/s12967-019-02159-0","article-title":"Inulin-type fructans supplementation improves glycemic control for the prediabetes and type 2 diabetes populations: results from a GRADE-assessed systematic review and dose\u2013response meta-analysis of 33 randomized controlled trials","volume":"17","author":"Wang","year":"2019","journal-title":"J Transl Med"},{"key":"10.1016\/j.diabres.2026.113102_b0325","unstructured":"(ClinicalTrials.gov. Clinical trials reported on the prebiotic and type 2 diabetes mellitus [Internet]. Bethesda (MD): U.S. National Library of Medicine; [cited 2025 Aug 10]. Available from: https:\/\/www.clinicaltrials.gov."},{"issue":"8","key":"10.1016\/j.diabres.2026.113102_b0330","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1038\/s42255-025-01336-4","article-title":"Combining a diet rich in fermentable carbohydrates with metformin improves glycaemic control and reshapes the gut microbiota in people with prediabetes","volume":"7","author":"Chu","year":"2025","journal-title":"Nat Metab"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0335","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2361491","article-title":"Gut microbiome encoded purine and amino acid pathways present prospective biomarkers for predicting metformin therapy efficacy in newly diagnosed T2D patients","volume":"16","author":"Elbere","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.diabres.2026.113102_b0340","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.molmet.2019.09.010","article-title":"Glucagon-like peptide 1 (GLP-1)","volume":"30","author":"M\u00fcller","year":"2019","journal-title":"Mol Metab"},{"issue":"7","key":"10.1016\/j.diabres.2026.113102_b0345","doi-asserted-by":"crossref","first-page":"498","DOI":"10.3390\/biology13070498","article-title":"The therapeutic potential of the specific intestinal Microbiome (SIM) diet on metabolic diseases","volume":"13","author":"Chu","year":"2024","journal-title":"Biology"},{"issue":"1","key":"10.1016\/j.diabres.2026.113102_b0350","doi-asserted-by":"crossref","first-page":"15582","DOI":"10.1038\/s41598-019-52103-x","article-title":"Metabolic and gut microbiome changes following GLP-1 or dual GLP-1\/GLP-2 receptor agonist treatment in diet-induced obese mice","volume":"9","author":"Madsen","year":"2019","journal-title":"Sci Rep"},{"issue":"13","key":"10.1016\/j.diabres.2026.113102_b0355","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.2165\/11592810-000000000-00000","article-title":"Glucagon-like peptide-1 analogues for Type 2 diabetes mellitus: current and emerging agents","volume":"71","author":"Gallwitz","year":"2011","journal-title":"Drugs"},{"issue":"10","key":"10.1016\/j.diabres.2026.113102_b0360","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1161\/ATVBAHA.116.307930","article-title":"GLP-1\u2013based therapies have no microvascular effects in type 2 diabetes mellitus: an acute and 12-week randomized, double-blind, placebo-controlled trial","volume":"36","author":"Smits","year":"2016","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"4","key":"10.1016\/j.diabres.2026.113102_b0365","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.bbrc.2019.01.023","article-title":"Alpha-glucosidase inhibitor 1-Deoxynojirimycin promotes beige remodeling of 3T3-L1 preadipocytes via activating AMPK","volume":"509","author":"Li","year":"2019","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.diabres.2026.113102_b0370","article-title":"Gut microbiota and antidiabetic drugs: perspectives of personalized treatment in type 2 diabetes mellitus","volume":"12","author":"Liu","year":"2022","journal-title":"Front Cell Infect Microbiol"}],"container-title":["Diabetes Research and Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822726000215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0168822726000215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T13:36:12Z","timestamp":1779111372000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0168822726000215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":74,"alternative-id":["S0168822726000215"],"URL":"https:\/\/doi.org\/10.1016\/j.diabres.2026.113102","relation":{},"ISSN":["0168-8227"],"issn-type":[{"value":"0168-8227","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic potential of prebiotics in modulating postprandial GLP-1, GLP-2, and glucose homeostasis in type 2 diabetes mellitus: Targeting gut dysbiosis and insulin resistance","name":"articletitle","label":"Article Title"},{"value":"Diabetes Research and Clinical Practice","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diabres.2026.113102","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113102"}}