{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T13:22:11Z","timestamp":1760016131302},"reference-count":42,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2007,12]]},"DOI":"10.1016\/j.diagmicrobio.2007.05.009","type":"journal-article","created":{"date-parts":[[2007,7,27]],"date-time":"2007-07-27T14:30:02Z","timestamp":1185546602000},"page":"425-432","source":"Crossref","is-referenced-by-count":35,"title":["Activity of meropenem as serine carbapenemases evolve in US Medical Centers: monitoring report from the MYSTIC Program (2006)"],"prefix":"10.1016","volume":"59","author":[{"given":"Paul R.","family":"Rhomberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lalitagauri M.","family":"Deshpande","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey T.","family":"Kirby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib1","doi-asserted-by":"crossref","first-page":"4760","DOI":"10.1128\/AAC.49.11.4760-4762.2005","article-title":"Kinetics study of KPC-3, a plasmid-encoded class A carbapenem-hydrolyzing \u03b2-lactamase","volume":"49","author":"Alba","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib2","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1128\/JCM.38.1.40-43.2000","article-title":"Convenient test for screening metallo-\u03b2-lactamase\u2013producing gram-negative bacteria by using thiol compounds","volume":"38","author":"Arakawa","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib3","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.diagmicrobio.2004.05.003","article-title":"Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997\u20132002)","volume":"50","author":"Biedenbach","year":"2004","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib4","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1086\/421495","article-title":"Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 \u03b2-lactamases in New York City","volume":"39","author":"Bradford","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib5","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1128\/AAC.49.2.776-778.2005","article-title":"Detection of KPC carbapenem-hydrolyzing enzymes in Enterobacter spp. from Brooklyn, New York","volume":"49","author":"Bratu","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib6","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1001\/archinte.165.12.1430","article-title":"Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium","volume":"165","author":"Bratu","year":"2005","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib7","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dki175","article-title":"Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents","volume":"56","author":"Bratu","year":"2005","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib8","series-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically: Approved Standard","author":"Clinical and Laboratory Standards Institute","year":"2006"},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib9","series-title":"Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria: Approved Standard","author":"Clinical and Laboratories Standards Institute","year":"2007"},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib10","series-title":"Performance Standards for Antimicrobial Susceptibility Testing, 17th Informational Supplement","author":"Clinical and Laboratory Standards Institute","year":"2007"},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib11","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.diagmicrobio.2006.07.004","article-title":"Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States Medical Centers: report from the MYSTIC Program (1999\u20132005)","volume":"56","author":"Deshpande","year":"2006","journal-title":"Diagn. Microbiol. Infect. Dis."},{"issue":"Suppl 2","key":"10.1016\/j.diagmicrobio.2007.05.009_bib12","doi-asserted-by":"crossref","first-page":"ii3","DOI":"10.1093\/jac\/dki297","article-title":"The Alexander Project: the benefits from a decade of surveillance","volume":"56","author":"Felmingham","year":"2005","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib13","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1086\/321893","article-title":"Antimicrobial resistance prevalence rates in hospital antibiograms reflect prevalence rates among pathogens associated with hospital-acquired infections","volume":"33","author":"Fridkin","year":"2001","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0732-8893(00)00222-4","article-title":"Carbapenem-resistant Serratia marcescens isolates producing Bush group 2f \u03b2-lactamase (SME-1) in the United States: results from the MYSTIC Programme","volume":"39","author":"Gales","year":"2001","journal-title":"Diagn. Microbiol. Infect. Dis."},{"issue":"Suppl 6","key":"10.1016\/j.diagmicrobio.2007.05.009_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/1120009X.2004.11782399","article-title":"PROTEKT years 1\u20133 (1999\u20132002): study design and methodology","volume":"16","author":"Harding","year":"2004","journal-title":"J. Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib16","doi-asserted-by":"crossref","first-page":"4438","DOI":"10.1128\/AAC.48.11.4438-4440.2004","article-title":"Plasmid-mediated carbapenem-hydrolyzing enzyme KPC-2 in an Enterobacter spp.","volume":"48","author":"Hossain","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.diagmicrobio.2004.03.016","article-title":"Determination of epidemic clonality among multidrug-resistant strains of Acinetobacter spp. and Pseudomonas aeruginosa in the MYSTIC Programme (USA, 1999\u20132003)","volume":"49","author":"Jones","year":"2004","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib18","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0732-8893(01)00318-2","article-title":"Determining the value of antimicrobial surveillance programs","volume":"41","author":"Jones","year":"2001","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib19","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.diagmicrobio.2005.10.006","article-title":"An overview of the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) Program: 1997\u20132004","volume":"53","author":"Jones","year":"2005","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib20","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1001\/archinte.162.13.1515","article-title":"Citywide clonal outbreak of multiresistant Acinetobacter baumannii and Pseudomonas aeruginosa in Brooklyn, NY: the preantibiotic era has returned","volume":"162","author":"Landman","year":"2002","journal-title":"Arch. Intern. Med."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib21","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1128\/AAC.49.1.71-76.2005","article-title":"Emergence of plasmid-mediated quinolone resistance in Escherichia coli in Europe","volume":"49","author":"Mammeri","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib22","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.diagmicrobio.2005.10.003","article-title":"Overview of the Meropenem Yearly Susceptibility Test Information Collection (1997\u20132004)","volume":"53","author":"Masterton","year":"2005","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib23","doi-asserted-by":"crossref","first-page":"4423","DOI":"10.1128\/AAC.49.10.4423-4424.2005","article-title":"Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC in a Klebsiella pneumoniae isolate from France","volume":"49","author":"Naas","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1046\/j.1469-0691.2002.00401.x","article-title":"Emerging carbapenemases in Gram-negative aerobes","volume":"8","author":"Nordmann","year":"2002","journal-title":"Clin. Microbiol. Infect."},{"issue":"Suppl B","key":"10.1016\/j.diagmicrobio.2007.05.009_bib25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1093\/jac\/46.suppl_2.25","article-title":"MYSTIC (Meropenem Yearly Susceptibility Test Information Collection) results from the Americas: resistance implications in the treatment of serious infections","volume":"46","author":"Pfaller","year":"2000","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib26","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0732-8893(01)00319-4","article-title":"Antimicrobial resistance trends in medical centers using carbapenems: report of 1999 and 2000 results from the MYSTIC program (USA)","volume":"41","author":"Pfaller","year":"2001","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib27","doi-asserted-by":"crossref","first-page":"3992","DOI":"10.1128\/AAC.00597-06","article-title":"Prevalence and genetic analysis of plasmid-mediated quinolone resistance determinants QnrA and QnrS in Enterobacteriaceae isolates from a French university hospital","volume":"50","author":"Poirel","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib28","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1111\/j.1469-0691.2006.01531.x","article-title":"Plasmid-mediated quinolone resistance determinant qnrS in Enterobacter cloacae","volume":"12","author":"Poirel","year":"2006","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib29","doi-asserted-by":"crossref","first-page":"999","DOI":"10.3201\/eid0908.030096","article-title":"NMC-A carbapenem-hydrolyzing enzyme in Enterobacter cloacae in North America","volume":"9","author":"Pottumarthy","year":"2003","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib30","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1128\/AAC.40.9.2080","article-title":"Characterization of IMI-1 \u03b2-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae","volume":"40","author":"Rasmussen","year":"1996","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib31","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1179\/joc.2005.17.5.459","article-title":"Comparative antimicrobial potency of meropenem tested against Gram-negative bacilli: report from the MYSTIC surveillance program in the United States (2004)","volume":"17","author":"Rhomberg","year":"2005","journal-title":"J. Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.diagmicrobio.2005.10.010","article-title":"Clonal occurrences of multidrug-resistant Gram-negative bacilli: report from the Meropenem Yearly Susceptibility Test Information Collection Surveillance Program in the United States (2004)","volume":"54","author":"Rhomberg","year":"2006","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib33","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.diagmicrobio.2006.07.009","article-title":"Contemporary activity of meropenem and comparator broad-spectrum agents: MYSTIC Program report from the United States component (2005)","volume":"57","author":"Rhomberg","year":"2007","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib34","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.diagmicrobio.2005.02.003","article-title":"Potency and spectrum trends for cefepime tested against 65,746 clinical bacterial isolates collected in North American medical centers: results from the SENTRY Antimicrobial Surveillance Program (1998\u20132003)","volume":"52","author":"Sader","year":"2005","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib35","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1128\/JCM.34.12.2909-2913.1996","article-title":"PCR detection of metallo-\u03b2-lactamase gene (blaIMP) in gram-negative rods resistant to broad-spectrum \u03b2-lactams","volume":"34","author":"Senda","year":"1996","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib36","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1128\/JCM.33.9.2233-2239.1995","article-title":"Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing","volume":"33","author":"Tenover","year":"1995","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib37","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.3201\/eid1208.060291","article-title":"Carbapenem resistance in Klebsiella pneumoniae not detected by automated susceptibility testing","volume":"12","author":"Tenover","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib38","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.diagmicrobio.2004.07.004","article-title":"Susceptibility of meropenem and comparators tested against 30,634 Enterobacteriaceae isolated in the MYSTIC Programme (1997\u20132003)","volume":"50","author":"Turner","year":"2004","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib39","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.diagmicrobio.2005.10.005","article-title":"Use of a program-specific website to disseminate surveillance data obtained from the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) Study","volume":"53","author":"Turner","year":"2005","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib40","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1128\/CMR.18.2.306-325.2005","article-title":"Metallo-\u03b2-lactamases: the quiet before the storm?","volume":"18","author":"Walsh","year":"2005","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib41","doi-asserted-by":"crossref","first-page":"4793","DOI":"10.1128\/AAC.48.12.4793-4799.2004","article-title":"Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A \u03b2-lactamase, KPC-3, in a New York Medical Center","volume":"48","author":"Woodford","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2007.05.009_bib42","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1128\/AAC.45.4.1151-1161.2001","article-title":"Novel carbapenem-hydrolyzing \u03b2-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae","volume":"45","author":"Yigit","year":"2001","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889307002325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889307002325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T17:22:16Z","timestamp":1629480136000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889307002325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,12]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,12]]}},"alternative-id":["S0732889307002325"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2007.05.009","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2007,12]]}}}