{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T20:01:12Z","timestamp":1774123272900,"version":"3.50.1"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.diagmicrobio.2008.08.022","type":"journal-article","created":{"date-parts":[[2008,11,8]],"date-time":"2008-11-08T01:48:13Z","timestamp":1226108893000},"page":"389-394","source":"Crossref","is-referenced-by-count":42,"title":["The role of a whole blood interferon-\u03b3 assay for the detection of latent tuberculosis infection in Bacille Calmette\u2013Gu\u00e9rin vaccinated children"],"prefix":"10.1016","volume":"62","author":[{"given":"Jin-Kyong","family":"Chun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang Ki","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyon-Suk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghee Young","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taek Jin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki Hwan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib1","series-title":"Red book: 2006 report of the Committee on Infectious Diseases","first-page":"678","article-title":"Tuberculosis","author":"American Academy of Pediatrics","year":"2006"},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib2","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1164\/rccm.200607-907ED","article-title":"Weighing gold or counting spots: which is more sensitive to diagnose latent tuberculosis infection?","volume":"174","author":"Barnes","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib3","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1136\/thx.2005.048033","article-title":"Performance of a whole blood interferon gamma assay for detecting latent infection with Mycobacterium tuberculosis in children","volume":"61","author":"Connell","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib4","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1086\/519266","article-title":"Interferon-gamma release assays improve the diagnosis of tuberculosis and nontuberculous mycobacterial disease in children in a country with a low incidence of tuberculosis","volume":"45","author":"Detjen","year":"2007","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib5","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1183\/09031936.06.00107005","article-title":"Avoiding the effect of BCG vaccination in detecting Mycobacterium tuberculosis infection with a blood test","volume":"28","author":"Diel","year":"2006","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib6","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1164\/rccm.200711-1613OC","article-title":"Predictive value of a whole blood IFN-gamma assay for the development of active tuberculosis disease after recent infection with Mycobacterium tuberculosis","volume":"177","author":"Diel","year":"2008","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib7","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/S0140-6736(06)68579-6","article-title":"Use in routine clinical practice of two commercial blood tests for diagnosis of infection with Mycobacterium tuberculosis: a prospective study","volume":"367","author":"Ferrara","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib8","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1111\/j.1440-1754.2007.01169.x","article-title":"Prevalence of positive tuberculin skin tests in foreign-born children","volume":"43","author":"Fortin","year":"2007","journal-title":"J. Paediatr. Child Health"},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib9","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0140-6736(06)69064-8","article-title":"Blood tests for diagnosis of tuberculosis","volume":"368","author":"Kampmann","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib10","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1001\/jama.293.22.2756","article-title":"Discrepancy between the tuberculin skin test and the whole-blood interferon gamma assay for the diagnosis of latent tuberculosis infection in an intermediate tuberculosis-burden country","volume":"293","author":"Kang","year":"2005","journal-title":"JAMA"},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib11","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1016\/j.rmed.2006.02.032","article-title":"Diagnosis of latent tuberculosis infection: the potential role of new technologies","volume":"100","author":"Kunst","year":"2006","journal-title":"Respir. Med."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib12","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1080\/00365540701730743","article-title":"Comparison of the interferon-gamma release assay and the tuberculin skin test for contact investigation of tuberculosis in BCG-vaccinated health care workers","volume":"40","author":"Lee","year":"2008","journal-title":"Scand. J. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib13","doi-asserted-by":"crossref","first-page":"340","DOI":"10.7326\/0003-4819-146-5-200703060-00006","article-title":"Meta-analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research","volume":"146","author":"Menzies","year":"2007","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib14","first-page":"513","article-title":"Prevalence and risk factors for latent tuberculosis infection among health care workers in Georgia","volume":"12","author":"Mirtskhulava","year":"2008","journal-title":"Int. J. Tuberc. Lung Dis."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1164\/rccm.200402-179OC","article-title":"Specific detection of tuberculosis infection: an interferon-gamma-based assay using new antigens","volume":"170","author":"Mori","year":"2004","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib16","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.3201\/eid1209.051606","article-title":"Risk for tuberculosis among children","volume":"12","author":"Nakaoka","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib17","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1586\/14737159.6.3.413","article-title":"New tools and emerging technologies for the diagnosis of tuberculosis: Part I. Latent tuberculosis","volume":"6","author":"Pai","year":"2006","journal-title":"Expert. Rev. Mol. Diagn."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib18","doi-asserted-by":"crossref","first-page":"5217","DOI":"10.4049\/jimmunol.167.9.5217","article-title":"Direct ex vivo analysis of antigen-specific IFN-gamma\u2013secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment","volume":"167","author":"Pathan","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1128\/CVI.13.1.53-58.2006","article-title":"Comparison of a new ESAT-6\/CFP-10 peptide-based gamma interferon assay and a tuberculin skin test for tuberculosis screening in a moderate-risk population","volume":"13","author":"Porsa","year":"2006","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib20","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1164\/rccm.200509-1516PP","article-title":"An update on the diagnosis of tuberculosis infection","volume":"174","author":"Richeldi","year":"2006","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib21","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1586\/14787210.3.6.981","article-title":"Diagnosis of latent Mycobacterium tuberculosis infection: is the demise of the Mantoux test imminent?","volume":"3","author":"Rothel","year":"2005","journal-title":"Expert Rev. Anti. Infect. Ther."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib22","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S1473-3099(03)00771-0","article-title":"Diagnosis and treatment of tuberculosis in children","volume":"3","author":"Shingadia","year":"2003","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib23","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/S1473-3099(03)00741-2","article-title":"Latent tuberculosis: mechanisms of host and bacillus that contribute to persistent infection","volume":"3","author":"Tufariello","year":"2003","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib24","doi-asserted-by":"crossref","first-page":"6073","DOI":"10.1128\/IAI.68.10.6073-6076.2000","article-title":"Increased numbers of ESAT-6- and purified protein derivative-specific gamma interferon-producing cells in subclinical and active tuberculosis infection","volume":"68","author":"Ulrichs","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.diagmicrobio.2008.08.022_bib25","first-page":"1242","article-title":"Contact tracing using a new T-cell-based test: better correlation with tuberculosis exposure than the tuberculin skin test","volume":"9","author":"Zellweger","year":"2005","journal-title":"Int. J. Tuberc. Lung. Dis."}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889308003982?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889308003982?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T16:26:58Z","timestamp":1545668818000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889308003982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S0732889308003982"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2008.08.022","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}