{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T13:48:04Z","timestamp":1768916884558,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1016\/j.diagmicrobio.2009.03.023","type":"journal-article","created":{"date-parts":[[2009,6,11]],"date-time":"2009-06-11T09:27:05Z","timestamp":1244712425000},"page":"300-304","source":"Crossref","is-referenced-by-count":19,"title":["In vitro antibacterial activity of tigecycline against resistant Gram-negative bacilli and enterococci by time\u2013kill assay"],"prefix":"10.1016","volume":"64","author":[{"given":"George A.","family":"Pankey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah S.","family":"Ashcraft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.diagmicrobio.2008.02.014","article-title":"Comparative time\u2013kill study of doxycycline, tigecycline, sulbactam, and imipenem against several clones of Acinetobacter baumannii","volume":"61","author":"Bantar","year":"2008","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib2","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1128\/AAC.46.3.892-895.2002","article-title":"In vitro activities of tigecycline (GAR-936) against recently isolated clinical bacteria in Spain","volume":"46","author":"Betriu","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib3","doi-asserted-by":"crossref","first-page":"3903","DOI":"10.1128\/AAC.49.9.3903-3909.2005","article-title":"Tigecycline MIC testing by broth dilution requires use of fresh medium or addition of the biocatalytic oxygen-reducing reagent oxyrase to standardize the test method","volume":"49","author":"Bradford","year":"2005","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib4","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dki175","article-title":"Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents","volume":"56","author":"Bratu","year":"2005","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib5","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1128\/AAC.01114-07","article-title":"Antimicrobial activities of tigecycline and other broad-spectrum antimicrobials tested against serine carbapenemase- and metallo-beta-lactamase\u2013producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program","volume":"52","author":"Castanheira","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib6","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1093\/jac\/dkg289","article-title":"In vitro activity of tigecycline (GAR-936), a novel glycylcycline, against vancomycin-resistant enterococci and staphylococci with diminished susceptibility to glycopeptides","volume":"52","author":"Cercenado","year":"2003","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib7","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1592\/phco.28.3.295","article-title":"In vitro activity of cefepime, imipenem, tigecycline, and gentamicin, alone and in combination, against extended-spectrum beta-lactamase\u2013producing Klebsiella pneumoniae and Escherichia coli","volume":"28","author":"Cha","year":"2008","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib8","series-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard","author":"CLSI","year":"2006"},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib9","series-title":"Performance standards for antimicrobial susceptibility testing: approved standard. 17th informational supplement","author":"CLSI","year":"2008"},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib10","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.diagmicrobio.2004.03.002","article-title":"In vitro activity of tigecycline (GAR-936) tested against 11,859 recent clinical isolates associated with community-acquired respiratory tract and gram-positive cutaneous infections","volume":"49","author":"Fritsche","year":"2004","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib11","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.diagmicrobio.2007.10.017","article-title":"Tigecycline activity tested against 11808 bacterial pathogens recently collected from US medical centers","volume":"60","author":"Gales","year":"2008","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib12","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1128\/JCM.43.1.199-207.2005","article-title":"Microbial DNA typing by automated repetitive-sequence-based PCR","volume":"43","author":"Healy","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib13","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/jac\/49.3.479","article-title":"Antibiotic resistance among clinical isolates of Acinetobacter in the UK, and in vitro evaluation of tigecycline (GAR-936)","volume":"49","author":"Henwood","year":"2002","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib14","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.diagmicrobio.2006.10.013","article-title":"Antimicrobial susceptibility of extended-spectrum beta-lactamase producers and multidrug-resistant Acinetobacter baumannii throughout the United States and comparative in vitro activity of tigecycline, a new glycylcycline antimicrobial","volume":"57","author":"Hoban","year":"2007","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib15","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1128\/AAC.47.1.216-222.2003","article-title":"Activity and diffusion of tigecycline (GAR-936) in experimental enterococcal endocarditis","volume":"47","author":"Lefort","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib16","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1592\/phco.22.17.1517.34117","article-title":"Antimicrobial activity of tigecycline (GAR-936) against Enterococcus faecium and Staphylococcus aureus used alone and in combination","volume":"22","author":"Mercier","year":"2002","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib17","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1476-0711-7-4","article-title":"In vitro activity of tigecycline and comparators against carbapenem-susceptible and resistant Acinetobacter baumannii clinical isolates in Italy","volume":"7","author":"Mezzatesta","year":"2008","journal-title":"Ann. Clin. Microbiol. Antimicrob."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib18","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1128\/AAC.47.1.400-404.2003","article-title":"Activities of the glycylcycline tigecycline (GAR-936) against 1,924 recent European clinical bacterial isolates","volume":"47","author":"Milatovic","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib19","doi-asserted-by":"crossref","first-page":"2940","DOI":"10.1128\/AAC.01581-07","article-title":"In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline\u2013amikacin synergy","volume":"52","author":"Moland","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib20","doi-asserted-by":"crossref","unstructured":"Mullangi, P.K., Pankey, G.A. (2008) Tigecycline in critical care. Crit. Care Clin. 24:365\u2013375, x.","DOI":"10.1016\/j.ccc.2007.12.007"},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib21","series-title":"Methods for determining bactericidal activity of antimicrobial agents; approved guideline","author":"National Committee for Clinical Laboratory Standards","year":"1999"},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib22","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.1128\/AAC.48.11.4479-4481.2004","article-title":"Activity of tigecycline (GAR-936) against Acinetobacter baumannii strains, including those resistant to imipenem","volume":"48","author":"Pach\u00f3n-Ib\u00e1\u00f1ez","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib23","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/jac\/dki248","article-title":"Tigecycline","volume":"56","author":"Pankey","year":"2005","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib24","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0732-8893(00)00193-0","article-title":"In vitro activity of GAR-936 against vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae","volume":"38","author":"Patel","year":"2000","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib25","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1128\/AAC.46.8.2595-2601.2002","article-title":"In vitro and in vivo activities of tigecycline (GAR-936), daptomycin, and comparative antimicrobial agents against glycopeptide-intermediate Staphylococcus aureus and other resistant gram-positive pathogens","volume":"46","author":"Petersen","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib26","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1128\/AAC.01099-06","article-title":"In vitro activities of various antimicrobials alone and in combination with tigecycline against carbapenem-intermediate or -resistant Acinetobacter baumannii","volume":"51","author":"Scheetz","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib27","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1128\/JCM.43.3.1187-1192.2005","article-title":"Clinical evaluation of the DiversiLab Microbial Typing System using repetitive-sequence-based PCR for characterization of Staphylococcus aureus strains","volume":"43","author":"Shutt","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib28","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1093\/jac\/dkm136","article-title":"In vitro activities of carbapenem\/sulbactam combination, colistin, colistin\/rifampicin combination and tigecycline against carbapenem-resistant Acinetobacter baumannii","volume":"60","author":"Song","year":"2007","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.03.023_bib29","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2174\/138161280401221007113202","article-title":"Recent developments in tetracycline antibiotics","volume":"4","author":"Sum","year":"1998","journal-title":"Curr. Pharm. Des."}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889309001308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889309001308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T17:02:25Z","timestamp":1685034145000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889309001308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S0732889309001308"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2009.03.023","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}