{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T06:23:00Z","timestamp":1763619780451},"reference-count":15,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.diagmicrobio.2009.10.015","type":"journal-article","created":{"date-parts":[[2009,11,28]],"date-time":"2009-11-28T02:31:17Z","timestamp":1259375477000},"page":"336-338","source":"Crossref","is-referenced-by-count":4,"title":["Antimicrobial susceptibility of multidrug-resistant Streptococcus pneumoniae strains with penicillin MICs of 8 to 32 mg\/L"],"prefix":"10.1016","volume":"66","author":[{"given":"Violeta","family":"Rodr\u00edguez-Cerrato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matilde","family":"Gracia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gema","family":"del Prado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Huelves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pl\u00ednio","family":"Naves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Ponte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Soriano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib1","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1128\/AAC.34.9.1655","article-title":"Efficacy of short courses of oral novobiocin\u2013rifampin in eradicating carrier state of methicillin-resistant Staphylococcus aureus and in vitro killing studies of clinical isolates","volume":"34","author":"Arathoon","year":"1990","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib2","series-title":"Performance standards for antimicrobial susceptibility testing: 18th informational supplement (M100-S18)","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2008"},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib3","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1128\/AAC.30.1.42","article-title":"Steady-state serum pharmacokinetics of novobiocin and rifampin alone and in combination","volume":"30","author":"Drusano","year":"1986","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib4","series-title":"Antibiotics in laboratory medicine","first-page":"330","article-title":"Antimicrobial combinations","author":"Eliopoulos","year":"1996"},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib5","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1093\/jac\/34.2.231","article-title":"Time\u2013kill studies of antibiotic combinations against penicillin-resistant and -susceptible Streptococcus pneumoniae","volume":"34","author":"Friedland","year":"1994","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib6","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1128\/AAC.26.6.933","article-title":"Susceptibility of multiply antibiotic-resistant pneumococci to the new quinoline antibiotics, nalidixic acid, coumermycin, and novobiocin","volume":"26","author":"Gombert","year":"1984","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0732-8893(89)90105-3","article-title":"Should novobiocin be clinically re-evaluated?","volume":"12","author":"Jones","year":"1989","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib8","first-page":"277","article-title":"Novobiocin, a new antibiotic; laboratory and clinical evaluation of thirty patients with bacterial pneumonia","volume":"2","author":"Limson","year":"1956","journal-title":"Antibiotic Med. Clin. Ther."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib9","doi-asserted-by":"crossref","first-page":"4166","DOI":"10.1128\/jb.177.14.4166-4170.1995","article-title":"Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance","volume":"177","author":"Mu\u00f1oz","year":"1995","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib10","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1086\/595857","article-title":"Changing epidemiology of antimicrobial-resistant Streptococcus pneumoniae in the United States, 2004\u20132005","volume":"48","author":"Richter","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib11","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1089\/mdr.1995.1.71","article-title":"Novel penicillin-resistant clones of Streptococcus pneumoniae in the Czech Republic and in Slovakia","volume":"1","author":"S\u00e1 Figueiredo","year":"1995","journal-title":"Microb. Drug Res."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib15","first-page":"51","article-title":"Novobiocin, a new antibiotic","volume":"75","author":"Shane","year":"1956","journal-title":"Can. Med. Assoc. J."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib12","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1093\/jac\/dkn392","article-title":"Breakthrough in penicillin resistance? Streptococcus pneumoniae isolates with penicillin\/cefotaxime MICs of 16 mg\/L and their genotypic and geographical relatedness.","volume":"62","author":"Soriano","year":"2008","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib13","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1128\/AAC.37.6.1334","article-title":"Randomized double-blinded trial of rifampin with either novobiocin or trimethoprim\u2013sulfamethoxazole against methicillin-resistant Staphylococcus aureus colonization: prevention of antimicrobial resistance and effect of host factors on outcome","volume":"37","author":"Walsh","year":"1993","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.diagmicrobio.2009.10.015_bib14","first-page":"27","article-title":"A study of the sensitizing potential of novobiocin","volume":"3","author":"Welch","year":"1956","journal-title":"Antibiotic Med. Clin. Ther."}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889309004258?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889309004258?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,15]],"date-time":"2018-12-15T00:58:49Z","timestamp":1544835529000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889309004258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0732889309004258"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2009.10.015","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}