{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T09:16:12Z","timestamp":1790241372917,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1016\/j.diagmicrobio.2013.03.032","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T08:47:47Z","timestamp":1367830067000},"page":"356-360","source":"Crossref","is-referenced-by-count":52,"title":["Trends in Klebsiella pneumoniae carbapenemase-positive K. pneumoniae in US hospitals: report from the 2007\u20132009 SENTRY Antimicrobial Surveillance Program"],"prefix":"10.1016","volume":"76","author":[{"given":"Robyn M.","family":"Kaiser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Castanheira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Tenover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"Lynfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0005","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1128\/JCM.00015-07","article-title":"Evaluation of methods to identify the Klebsiella pneumoniae carbapenemase in Enterobacteriaceae","volume":"45","author":"Anderson","year":"2007","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0010","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1086\/605922","article-title":"Attributable mortality rate for carbapenem-resistant Klebsiella pneumoniae bacteremia","volume":"30","author":"Borer","year":"2009","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0015","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1128\/AAC.49.7.3018-3020.2005","article-title":"Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York: epidemiology and recommendations for detection","volume":"49","author":"Bratu","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0020","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1001\/archinte.165.12.1430","article-title":"Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City: a new threat to our antibiotic armamentarium","volume":"165","author":"Bratu","year":"2005","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0025","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/jac\/dki175","article-title":"Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agents","volume":"56","author":"Bratu","year":"2005","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0030","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/S1473-3099(11)70183-9","article-title":"Tigecycline: benefits and risks","volume":"11","author":"Cai","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0035","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1089\/mdr.2009.0031","article-title":"Antimicrobial susceptibility patterns of KPC-producing or CTX-M-producing Enterobacteriaceae","volume":"16","author":"Castanheira","year":"2010","journal-title":"Microb Drug Resist"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0040","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/jac\/dkr081","article-title":"Trends in carbapenemase-producing Escherichia coli and Klebsiella spp. from Europe and the Americas: report from the SENTRY antimicrobial surveillance programme (2007\u201309)","volume":"66","author":"Castanheira","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0045","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1128\/AAC.01497-10","article-title":"Early dissemination of NDM-1- and OXA-181-producing Enterobacteriaceae in Indian hospitals: report from the SENTRY Antimicrobial Surveillance Program, 2006\u20132007","volume":"55","author":"Castanheira","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0050","series-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2009"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0055","series-title":"Performance standards for antimicrobial susceptibility testing; 20th informational supplement (M100-S20)","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2010"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0060","series-title":"Performance standards for antimicrobial susceptibility testing; 22nd informational supplement (M100-S22)","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2012"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0065","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1093\/jac\/dkr290","article-title":"Longitudinal survey of carbapenem resistance and resistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007\u201309","volume":"66","author":"Davies","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0070","doi-asserted-by":"crossref","first-page":"4503","DOI":"10.1128\/AAC.01707-09","article-title":"Colistin dosing and nephrotoxicity in a large community teaching hospital","volume":"54","author":"Deryke","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0075","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1089\/mdr.2006.12.223","article-title":"Occurrence and characterization of carbapenemase-producing Enterobacteriaceae: report from the SENTRY Antimicrobial Surveillance Program (2000\u20132004)","volume":"12","author":"Deshpande","year":"2006","journal-title":"Microb Drug Resist"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0080","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1093\/jac\/dkn547","article-title":"Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA","volume":"63","author":"Endimiani","year":"2009","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0085","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.1128\/JCM.02458-09","article-title":"Evaluation of updated interpretative criteria for categorizing Klebsiella pneumoniae with reduced carbapenem susceptibility","volume":"48","author":"Endimiani","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0090","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.3201\/eid1606.091671","article-title":"Transfer of carbapenem-resistant plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in patient","volume":"16","author":"Goren","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0095","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/cid\/cir202","article-title":"Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention","volume":"53","author":"Gupta","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0100","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1086\/599225","article-title":"Nephrotoxicity associated with intravenous colistin (colistimethate sodium) treatment at a tertiary care medical center","volume":"48","author":"Hartzell","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0105","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1086\/598244","article-title":"Carbapenem resistance among Klebsiella pneumoniae isolates: risk factors, molecular characteristics, and susceptibility patterns","volume":"30","author":"Hussein","year":"2009","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0110","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1128\/AAC.00784-09","article-title":"Regional dissemination of KPC-producing Klebsiella pneumoniae","volume":"53","author":"Kitchel","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0115","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.1128\/AAC.00008-10","article-title":"Genetic factors associated with elevated carbapenem resistance in KPC-producing Klebsiella pneumoniae","volume":"54","author":"Kitchel","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0120","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1093\/jac\/dkm129","article-title":"Evolution of antimicrobial resistance among Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae in Brooklyn, NY","volume":"60","author":"Landman","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0125","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1099\/jmm.0.012575-0","article-title":"Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae","volume":"58","author":"Landman","year":"2009","journal-title":"J Med Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0130","doi-asserted-by":"crossref","first-page":"3931","DOI":"10.1128\/JCM.01176-11","article-title":"Accuracy of carbapenem nonsusceptibility for identification of KPC-possessing Enterobacteriaceae by use of the revised CLSI breakpoints","volume":"49","author":"Landman","year":"2011","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0135","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/jac\/dks063","article-title":"Transmission of carbapenem-resistant pathogens in New York City hospitals: progress and frustration","volume":"67","author":"Landman","year":"2012","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0140","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1592\/phco.30.12.1279","article-title":"Resurgence of colistin: a review of resistance, toxicity, pharmacodynamics, and dosing","volume":"30","author":"Lim","year":"2010","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0145","doi-asserted-by":"crossref","first-page":"4239","DOI":"10.1128\/JCM.05297-11","article-title":"IMP-producing carbapenem-resistant Klebsiella pneumoniae in the United States","volume":"49","author":"Limbago","year":"2011","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0150","doi-asserted-by":"crossref","first-page":"e00204","DOI":"10.1128\/mBio.00204-11","article-title":"Molecular dissection of an outbreak of carbapenem-resistant Enterobacteriaceae reveals intergenus KPC carbapenemase transmission through a promiscuous plasmid","volume":"2","author":"Mathers","year":"2011","journal-title":"MBio"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0155","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1111\/j.1469-0691.2011.03572.x","article-title":"Outbreak of KPC-3-producing, and colistin-resistant, Klebsiella pneumoniae infections in two Sicilian hospitals","volume":"17","author":"Mezzatesta","year":"2011","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0160","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.diagmicrobio.2010.10.013","article-title":"Treatment and outcomes in carbapenem-resistant Klebsiella pneumoniae bloodstream infections","volume":"69","author":"Neuner","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0165","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S1473-3099(09)70054-4","article-title":"The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria","volume":"9","author":"Nordmann","year":"2009","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0170","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.3201\/eid1710.110655","article-title":"Global spread of carbapenemase-producing Enterobacteriaceae","volume":"17","author":"Nordmann","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0175","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1086\/592412","article-title":"Outcomes of carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial and adjunctive therapies","volume":"29","author":"Patel","year":"2008","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0180","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1128\/CMR.00001-07","article-title":"Carbapenemases: the versatile beta-lactamases","volume":"20","author":"Queenan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0185","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.3201\/eid1708.060291","article-title":"Carbapenem resistance in Klebsiella pneumoniae not detected by automated susceptibility testing","volume":"12","author":"Tenover","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0190","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.diagmicrobio.2009.02.004","article-title":"Clinical outcomes of patients with Klebsiella pneumoniae carbapenemase-producing K. pneumoniae after treatment with imipenem or meropenem","volume":"64","author":"Weisenberg","year":"2009","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0195","doi-asserted-by":"crossref","first-page":"4793","DOI":"10.1128\/AAC.48.12.4793-4799.2004","article-title":"Outbreak of Klebsiella pneumoniae producing a new carbapenem-hydrolyzing class A beta-lactamase, KPC-3, in a New York Medical Center","volume":"48","author":"Woodford","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0200","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1128\/JCM.39.12.4433-4439.2001","article-title":"Outbreak of infection with multidrug-resistant Klebsiella pneumoniae carrying bla(IMP-8) in a university medical center in Taiwan","volume":"39","author":"Yan","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0205","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1128\/AAC.45.4.1151-1161.2001","article-title":"Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae","volume":"45","author":"Yigit","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.03.032_bb0210","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1128\/JCM.02301-09","article-title":"Risk factors and outcomes associated with acquisition of colistin-resistant KPC-producing Klebsiella pneumoniae: a matched case\u2013control study","volume":"48","author":"Zarkotou","year":"2010","journal-title":"J Clin Microbiol"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889313002046?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889313002046?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,16]],"date-time":"2018-10-16T05:55:27Z","timestamp":1539669327000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889313002046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0732889313002046"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2013.03.032","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}