{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T20:53:51Z","timestamp":1789851231809,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1016\/j.diagmicrobio.2013.11.025","type":"journal-article","created":{"date-parts":[[2013,12,6]],"date-time":"2013-12-06T17:45:24Z","timestamp":1386351924000},"page":"443-448","source":"Crossref","is-referenced-by-count":189,"title":["Antimicrobial susceptibility of Gram-negative organisms isolated from patients hospitalized in intensive care units in United States and European hospitals (2009\u20132011)"],"prefix":"10.1016","volume":"78","author":[{"given":"Helio S.","family":"Sader","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Farrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Flamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald N.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0005","doi-asserted-by":"crossref","first-page":"3986","DOI":"10.1128\/JCM.01242-11","article-title":"Containment of an outbreak of KPC-3-producing Klebsiella pneumoniae in Italy","volume":"49","author":"Agodi","year":"2011","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0010","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1093\/cid\/cit152","article-title":"10 \u00d7 \u203220 Progress\u2014Development of new drugs active against Gram-negative bacilli: an update from the Infectious Diseases Society of America","volume":"56","author":"Boucher","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0015","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01896-13","article-title":"Contemporary diversity of \u03b2-lactamases among Enterobacteriaceae in the nine United States census regions and ceftazidime-avibactam activity tested against isolates producing the most prevalent \u03b2-lactamase groups","author":"Castanheira","year":"2014","journal-title":"Antimicro Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0020","author":"Centers for Disease Control and Prevention (CDC)"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0145","series-title":"Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard (M07-A9)","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2012"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0150","series-title":"Performance standards for antimicrobial susceptibility testing: 23rd informational supplement (M100-S23)","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2013"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0035","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s10096-012-1741-4","article-title":"Thirteen years of antibiotic susceptibility surveillance of Pseudomonas aeruginosa from intensive care units and urology services in the Netherlands","volume":"32","author":"Croughs","year":"2013","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0155","author":"EUCAST"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0160","author":"European Centre for Disease Prevention, Control. (ECDC)"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0050","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ccc.2010.11.002","article-title":"Antimicrobial resistance in the intensive care unit: mechanisms, epidemiology, and management of specific resistant pathogens","volume":"27","author":"Fraimow","year":"2011","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0055","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES2013.18.28.20525","article-title":"Carbapenemase-producing Enterobacteriaceae in Europe: a survey among national experts from 39 countries, February 2013","volume":"18","author":"Glasner","year":"2013","journal-title":"Euro Surveill"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0060","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00134-008-1237-y","article-title":"Surveillance of microbial resistance in European Intensive Care Units: a first report from the Care-ICU programme for improved infection control","volume":"35","author":"Hanberger","year":"2009","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0065","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.diagmicrobio.2013.03.032","article-title":"Trends in Klebsiella pneumoniae carbapenemase-positive K. pneumoniae in US hospitals: report from the 2007\u20132009 SENTRY Antimicrobial Surveillance Program","volume":"76","author":"Kaiser","year":"2013","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0070","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1128\/AAC.00126-09","article-title":"Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258","volume":"53","author":"Kitchel","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0075","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1177\/0897190010388906","article-title":"Infectious diseases in the critically ill patients","volume":"24","author":"Martin","year":"2011","journal-title":"J Pharm Pract"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0080","doi-asserted-by":"crossref","first-page":"4833","DOI":"10.1128\/AAC.00750-12","article-title":"Influence of multidrug resistance and appropriate empirical therapy on the 30-day mortality rate of Pseudomonas aeruginosa bacteremia","volume":"56","author":"Morata","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0085","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.3201\/eid1710.110655","article-title":"Global spread of carbapenemase-producing Enterobacteriaceae","volume":"17","author":"Nordmann","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0090","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1056\/NEJMra0904124","article-title":"Hospital-acquired infections due to gram-negative bacteria","volume":"362","author":"Peleg","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0095","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1093\/jac\/dkm279","article-title":"Impact of antibiotic resistance and of adequate empirical antibiotic treatment in the prognosis of patients with Escherichia coli bacteraemia","volume":"60","author":"Peralta","year":"2007","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0100","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1128\/AAC.00462-11","article-title":"Impact of inadequate empirical therapy on the mortality of patients with bloodstream infections: a propensity score-based analysis","volume":"56","author":"Retamar","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0105","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ijantimicag.2010.08.005","article-title":"In vivo development of antimicrobial resistance in Pseudomonas aeruginosa strains isolated from the lower respiratory tract of intensive care unit patients with nosocomial pneumonia and receiving antipseudomonal therapy","volume":"36","author":"Riou","year":"2010","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0110","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.ajic.2011.05.020","article-title":"International Nosocomial Infection Control Consortium (INICC) report, data summary of 36 countries, for 2004\u20132009","volume":"40","author":"Rosenthal","year":"2012","journal-title":"Am J Infect Control"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/668770","article-title":"Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009\u20132010","volume":"34","author":"Sievert","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0120","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1086\/671270","article-title":"Prevalence and risk factors for acquisition of carbapenem-resistant enterobacteriaceae in the setting of endemicity","volume":"34","author":"Swaminathan","year":"2013","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0125","series-title":"Tygacil\u00ae Package Insert","year":"2012"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0130","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1001\/jama.2009.1754","article-title":"International study of the prevalence and outcomes of infection in intensive care units","volume":"302","author":"Vincent","year":"2009","journal-title":"JAMA"},{"issue":"Suppl 3","key":"10.1016\/j.diagmicrobio.2013.11.025_bb0135","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1016\/S0924-8579(10)70004-2","article-title":"Emerging carbapenemases: a global perspective","volume":"36","author":"Walsh","year":"2010","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.diagmicrobio.2013.11.025_bb0140","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1586\/eri.09.108","article-title":"Multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii: resistance mechanisms and implications for therapy","volume":"8","author":"Zavascki","year":"2010","journal-title":"Expert Rev Anti Infect Ther"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288931300638X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288931300638X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,8]],"date-time":"2018-10-08T11:20:14Z","timestamp":1538997614000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073288931300638X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S073288931300638X"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2013.11.025","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]}}}