{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:48:12Z","timestamp":1770886092960,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","dmidjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1016\/j.diagmicrobio.2016.10.022","type":"journal-article","created":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T06:30:37Z","timestamp":1477377037000},"page":"160-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["In vitro activity of tigecycline alone and antimicrobial combinations against clinical Neisseria gonorrhoeae isolates"],"prefix":"10.1016","volume":"87","author":[{"given":"Hyukmin","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunsoo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Hee","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongeun","family":"Yong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seok Hoon","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyungwon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Younsop","family":"Chong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0005","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1093\/jac\/dkt540","article-title":"In vitro synergy testing of novel antimicrobial combination therapies against Neisseria gonorrhoeae","volume":"69","author":"Barbee","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0010","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/jac\/dkv321","article-title":"First nationwide study regarding ceftriaxone resistance and molecular epidemiology of Neisseria gonorrhoeae in China","volume":"71","author":"Chen","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0015","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1007\/s10156-013-0597-6","article-title":"In vitro activities of antimicrobial combinations against clinical isolates of Neisseria gonorrhoeae","volume":"19","author":"Furuya","year":"2013","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0020","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/s10156-006-0445-Z","article-title":"In vitro synergistic effects of double combinations of beta-lactams and azithromycin against clinical isolates of Neisseria gonorrhoeae","volume":"12","author":"Furuya","year":"2006","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0025","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1128\/AAC.04536-14","article-title":"In vitro activity of fosfomycin alone and in combination with ceftriaxone or azithromycin against clinical Neisseria gonorrhoeae isolates","volume":"59","author":"Hauser","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0030","series-title":"Clinical microbiology procedures handbook","first-page":"5.0.1","article-title":"Evaluating antimicrobial susceptibility test","author":"Hindler","year":"2010"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0035","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1093\/cid\/ciu521","article-title":"The efficacy and safety of gentamicin plus azithromycin and gemifloxacin plus azithromycin as treatment of uncomplicated gonorrhea","volume":"59","author":"Kirkcaldy","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0040","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1586\/14787210.2016.1134315","article-title":"New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae","volume":"14","author":"Lee","year":"2016","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0045","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1093\/jac\/dkv146","article-title":"Emergence of decreased susceptibility and resistance to extended-spectrum cephalosporins in Neisseria gonorrhoeae in Korea","volume":"70","author":"Lee","year":"2015","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0050","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/00007435-199501000-00007","article-title":"Treating uncomplicated Neisseria gonorrhoeae infections: is the anatomic site of infection important?","volume":"22","author":"Moran","year":"1995","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0055","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1093\/jac\/dkq116","article-title":"Should tigecycline be considered for urinary tract infections? A pharmacokinetic re-evaluation","volume":"65","author":"Nix","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0060","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1093\/jac\/dks449","article-title":"Combination therapy for gonorrhoea: in vitro synergy testing","volume":"68","author":"Pereira","year":"2013","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0065","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1128\/AAC.45.3.734-738.2001","article-title":"Correlation of in vitro susceptibilities to newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains with changes in GyrA and ParC","volume":"45","author":"Shultz","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0070","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1186\/s12879-015-1029-2","article-title":"Current and future antimicrobial treatment of gonorrhoea\u2014the rapidly evolving Neisseria gonorrhoeae continues to challenge","volume":"15","author":"Unemo","year":"2015","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0075","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1128\/CMR.00010-14","article-title":"Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future","volume":"27","author":"Unemo","year":"2014","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.diagmicrobio.2016.10.022_bb0080","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.ijantimicag.2014.10.020","article-title":"Determination of in vitro synergy for dual antimicrobial therapy against resistant Neisseria gonorrhoeae using Etest and agar dilution","volume":"45","author":"Wind","year":"2015","journal-title":"Int J Antimicrob Agents"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889316303650?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889316303650?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T08:26:57Z","timestamp":1536308817000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889316303650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S0732889316303650"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2016.10.022","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In vitro activity of tigecycline alone and antimicrobial combinations against clinical Neisseria gonorrhoeae isolates","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2016.10.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}