{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:20:26Z","timestamp":1773285626152,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Research Program on Emerging and Re-emerging Infectious Diseases from the Japan Agency Development","award":["JP 17fk0108208"],"award-info":[{"award-number":["JP 17fk0108208"]}]},{"DOI":"10.13039\/100009619","name":"AMED","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"name":"JSPS KAKENHI","award":["16K09939"],"award-info":[{"award-number":["16K09939"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.diagmicrobio.2019.01.018","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T03:34:07Z","timestamp":1548819247000},"page":"287-292","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Mortality caused by extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae bacteremia; a case control study: alert to Enterobacteriaceae strains with high minimum inhibitory concentrations of piperacillin\/tazobactam"],"prefix":"10.1016","volume":"94","author":[{"given":"Hiroki","family":"Namikawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazushi","family":"Yamairi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wataru","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Etsuko","family":"Takizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Niki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyotaka","family":"Nakaie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken-Ichi","family":"Oinuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamiko","family":"Niki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Takemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taichi","family":"Shuto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kakeya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0005","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1056\/NEJMra1208623","article-title":"Severe sepsis and septic shock","volume":"369","author":"Angus","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0010","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.idc.2007.08.008","article-title":"Fever of unknown origin in febrile leukopenia","volume":"21","author":"Antoniadou","year":"2007","journal-title":"Infect Dis Clin N Am"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0015","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1086\/604713","article-title":"A multinational survey of risk factors for infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae in nonhospitalized patients","volume":"49","author":"Ben-Ami","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0020","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1007\/s10096-017-3077-6","article-title":"Association between dementia and reduced walking ability and 30-day mortality in patients with extended-spectrum beta-lactamase-producing Escherichia coli bacteremia","volume":"36","author":"Chapelet","year":"2017","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0025","series-title":"Performance standards for antimicrobial susceptibility testing; 26th informational supplement. M100-S26","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2016"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijid.2015.07.010","article-title":"Prevalence, risk factors, and impact on clinical outcome of extended-spectrum beta- lactamase-producing Escherichia coli bacteraemia: a five-year study","volume":"39","author":"Denis","year":"2015","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0035","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1128\/AAC.01523-12","article-title":"Appropriateness of empirical treatment and outcome in bacteremia caused by extended-spectrum-\u03b2-lactamase\u2013producing bacteria","volume":"57","author":"Frakking","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0040","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.rcl.2012.02.002","article-title":"Infectious and inflammatory diseases of the kidney","volume":"50","author":"Hammond","year":"2012","journal-title":"Radiol Clin N Am"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0045","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1056\/NEJMcp1104429","article-title":"Clinical practice. Uncomplicated urinary tract infection","volume":"366","author":"Hooton","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0050","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1128\/AAC.48.12.4574-4581.2004","article-title":"Bloodstream infections due to extended- spectrum beta-lactamase\u2013producing Escherichia coli and Klebsiella pneumoniae: risk factors for mortality and treatment outcome, with special emphasis on antimicrobial therapy","volume":"48","author":"Kang","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0055","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s00277-012-1631-y","article-title":"Escherichia coli and Klebsiella pneumoniae bacteremia in patients with neutropenic fever: factors associated with extended-spectrum \u03b2-lactamase production and its impact on outcome","volume":"92","author":"Kim","year":"2013","journal-title":"Ann Hematol"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0060","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1093\/cid\/cis916","article-title":"Cefepime therapy for monomicrobial bacteremia caused by cefepime-susceptible extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae: MIC matters","volume":"56","author":"Lee","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0065","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jmii.2017.05.006","article-title":"Propensity-matched analysis of the impact of extended-spectrum \u03b2-lactamase production on adults with community-onset Escherichia coli, Klebsiella species, and Proteus mirabilis bacteremia","volume":"51","author":"Lee","year":"2018","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0070","article-title":"Antimicrobial resistance patterns, clinical features, and risk factors for septic shock and death of nosocomial E coli bacteremia in adult patients with hematological disease: a monocenter retrospective study in China","volume":"96","author":"Ma","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0075","first-page":"392","article-title":"Extended-spectrum \u03b2-lactamase producing Klebsiella pneumoniae from blood cultures in Puducherry, India","volume":"134","author":"Parveen","year":"2011","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0080","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1128\/CMR.18.4.657-686.2005","article-title":"Extended-spectrum beta-lactamases: a clinical update","volume":"18","author":"Paterson","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0085","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/cid\/cir793","article-title":"Can we really use \u00df-lactam\/\u00df-lactam inhibitor combinations for the treatment of infections caused by extended-spectrum \u00df-lactamase-producing bacteria?","volume":"54","author":"Perez","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0090","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/1472-6963-14-162","article-title":"Time to antibiotics and outcomes in cancer patients with febrile neutropenia","volume":"14","author":"Perron","year":"2014","journal-title":"BMC Health Serv Res"},{"issue":"Suppl. 1","key":"10.1016\/j.diagmicrobio.2019.01.018_bb0095","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1469-0691.2007.01864.x","article-title":"Antibiotic policy and prescribing strategies for therapy of extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae: the role of piperacillin-tazobactam","volume":"14","author":"Peterson","year":"2008","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0100","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1473-3099(08)70041-0","article-title":"Extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae: an emerging public-health concern","volume":"8","author":"Pitout","year":"2008","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0105","doi-asserted-by":"crossref","first-page":"3402","DOI":"10.1128\/AAC.00135-13","article-title":"Impact of the MIC of piperacillin-tazobactam on the outcome of patients with bacteremia due to extended-spectrum-\u03b2-lactamase\u2013producing Escherichia coli","volume":"57","author":"Retamar","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0110","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/cid\/cir790","volume":"54","author":"Rodr\u00edguez-Ba\u00f1o","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0115","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1001\/jama.2016.0287","article-title":"The third international consensus definitions for sepsis and septic shock (Sepsis-3)","volume":"315","author":"Singer","year":"2016","journal-title":"JAMA"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0120","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jiac.2016.07.019","article-title":"Proposed breakpoint of piperacillin\/tazobactam against extended spectrum \u03b2-lactamases producing bacteria in bacteremia","volume":"23","author":"Sugimoto","year":"2017","journal-title":"J Infect Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0125","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.jmii.2010.08.004","article-title":"Clinical manifestations and prognostic factors in cancer patients with bacteremia due to extended-spectrum \u03b2-lactamase\u2013producing Escherichia coli or Klebsiella pneumoniae","volume":"44","author":"Wang","year":"2011","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.diagmicrobio.2019.01.018_bb0130","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1620\/tjem.224.61","article-title":"Clinical features of bacteremia caused by methicillin-resistant Staphylococcus aureus in a tertiary hospital","volume":"224","author":"Yamada","year":"2011","journal-title":"Tohoku J Exp Med"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889319301002?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889319301002?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,10,25]],"date-time":"2019-10-25T02:15:10Z","timestamp":1571969710000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889319301002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["S0732889319301002"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2019.01.018","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mortality caused by extended-spectrum beta-lactamase\u2013producing Enterobacteriaceae bacteremia; a case control study: alert to Enterobacteriaceae strains with high minimum inhibitory concentrations of piperacillin\/tazobactam","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2019.01.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}