{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:49:11Z","timestamp":1787759351253,"version":"build-2784847793"},"reference-count":18,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.diagmicrobio.2019.06.002","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T13:43:34Z","timestamp":1560260614000},"page":"114850","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Frequency of occurrence and antimicrobial susceptibility of bacteria isolated from patients hospitalized with bloodstream infections in United States medical centers (2015\u20132017)"],"prefix":"10.1016","volume":"95","author":[{"given":"Helio S.","family":"Sader","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Castanheira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Streit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Flamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0005","unstructured":"AVYCAZ\u00ae (ceftazidime\u2013avibactam). 2018 Available at https:\/\/www.allergan.com\/assets\/pdf\/avycaz_pi February 2018"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0010","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.diagmicrobio.2018.11.021","article-title":"Antimicrobial activity of ceftolozane\u2013tazobactam tested against gram-negative contemporary (2015\u20132017) isolates from hospitalized patients with pneumonia in US medical centers","volume":"94","author":"Carvalhaes","year":"2019","journal-title":"Diagn Microbiol"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0015","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00567-17","article-title":"Meropenem\u2013vaborbactam tested against contemporary Gram-negative isolates collected worldwide during 2014, including carbapenem-resistant, KPC-producing, multidrug-resistant, and extensively drug-resistant Enterobacteriaceae","volume":"61","author":"Castanheira","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0020","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00313-18","article-title":"In vitro activity of plazomicin against Gram-negative and Gram-positive isolates collected from U.S. hospitals and comparative activities of aminoglycosides against carbapenem-resistant Enterobacteriaceae and isolates carrying carbapenemase genes","volume":"62","author":"Castanheira","year":"2018","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0025","unstructured":"Centers for Disease Control & Prevention (CDC). 2019. Bloodstream infection event (central line-associated bloodstream infection and non-central line associated bloodstream infection). Available at https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/4psc_clabscurrent.pdf. Accessed December 18, 2018."},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0030","series-title":"M07Ed11E. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2018"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0035","series-title":"Performance standards for antimicrobial susceptibility testing: 28th informational supplement","article-title":"M100Ed28E","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2018"},{"issue":"January 2018","key":"10.1016\/j.diagmicrobio.2019.06.002_bb0040","article-title":"Breakpoint tables for interpretation of MIC's and zone diameters","author":"EUCAST","year":"2018","journal-title":"Version 80"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0045","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/1469-0691.12195","article-title":"Overall burden of bloodstream infection and nosocomial bloodstream infection in North America and Europe","volume":"19","author":"Goto","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/ice.2017.236","article-title":"Pathogen distribution and antimicrobial resistance among pediatric healthcare-associated infections reported to the National Healthcare Safety Network, 2011-2014","volume":"39","author":"Lake","year":"2018","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0055","doi-asserted-by":"crossref","first-page":"927","DOI":"10.2217\/fmb-2017-0118","article-title":"How should we best treat patients with bloodstream infections?","volume":"12","author":"Lopez-Cortes","year":"2017","journal-title":"Future Microbiol"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0060","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1128\/AAC.00462-11","article-title":"Impact of inadequate empirical therapy on the mortality of patients with bloodstream infections: a propensity score-based analysis","volume":"56","author":"Retamar","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0065","doi-asserted-by":"crossref","first-page":"3053","DOI":"10.1093\/jac\/dky279","article-title":"Frequency and antimicrobial susceptibility of gram-negative bacteria isolated from patients with pneumonia hospitalized in ICUs of US medical centres (2015-17)","volume":"73","author":"Sader","year":"2018","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0070","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01587-18","article-title":"Antimicrobial susceptibility of Pseudomonas aeruginosa to ceftazidime\u2013avibactam, ceftolozane\u2013tazobactam, piperacillin\u2013tazobactam, and meropenem stratified by U.S. census divisions: results from the 2017 INFORM program","volume":"62","author":"Sader","year":"2018","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0075","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/cid\/ciw649","article-title":"The effect of molecular rapid diagnostic testing on clinical outcomes in bloodstream infections: a systematic review and meta-analysis","volume":"64","author":"Timbrook","year":"2017","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0080","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1186\/1471-2334-14-489","article-title":"Treatment of bloodstream infections in ICUs","volume":"14","author":"Timsit","year":"2014","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0085","unstructured":"US FDA. 2019. Antibacterial susceptibility test interpretive criteria. Available at https:\/\/www.fda.gov\/drugs\/development-resources\/antibacterial-susceptibility-test-interpretive-criteria. Accessed 05 May 2019."},{"key":"10.1016\/j.diagmicrobio.2019.06.002_bb0090","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1017\/ice.2016.174","article-title":"Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011-2014","volume":"37","author":"Weiner","year":"2016","journal-title":"Infect Control Hosp Epidemiol"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889319301841?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889319301841?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T09:53:10Z","timestamp":1760003590000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889319301841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S0732889319301841"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2019.06.002","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frequency of occurrence and antimicrobial susceptibility of bacteria isolated from patients hospitalized with bloodstream infections in United States medical centers (2015\u20132017)","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2019.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114850"}}