{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:34:08Z","timestamp":1760056448726,"version":"build-2065373602"},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.diagmicrobio.2021.115429","type":"journal-article","created":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T17:43:03Z","timestamp":1621186983000},"page":"115429","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Documentation of a false positive Lyme disease serologic test in a patient with untreated Babesia microti infection carries implications for accurately determining the frequency of Lyme disease coinfections"],"prefix":"10.1016","volume":"101","author":[{"given":"Gary P.","family":"Wormser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0002","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/infdis\/152.3.473","article-title":"Serological evidence for simultaneous occurrences of Lyme disease and babesiosis","volume":"152","author":"Benach","year":"1985","journal-title":"J Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0001","first-page":"590","article-title":"Recommendations for test performance and interpretation from the second national conference on serologic diagnosis of Lyme disease","volume":"44","year":"1995","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2021.115429_bib0003","doi-asserted-by":"crossref","first-page":"e80","DOI":"10.1371\/journal.ppat.0030080","article-title":"A molecular link between malaria and Epstein-Barr virus reactivation","volume":"3","author":"Chene","year":"2007","journal-title":"PLoS Pathog"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2021.115429_bib0004","doi-asserted-by":"crossref","first-page":"31","DOI":"10.5501\/wjv.v1.i1.31","article-title":"Serological diagnosis of Epstein-Barr virus infection: Problems and solutions","volume":"1","author":"De Paschale","year":"2012","journal-title":"World J Virol"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0005","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1128\/CVI.00075-07","article-title":"Dominant epitopes of the C6 diagnostic peptide of Borrelia burgdorferi are largely inaccessible to antibody on the parent VlsE molecule","volume":"14","author":"Embers","year":"2007","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0006","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1128\/jcm.33.2.419-427.1995","article-title":"Immunoblot interpretation criteria for serodiagnosis of early Lyme disease","volume":"33","author":"Engstrom","year":"1995","journal-title":"J Clin Microbiol"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2021.115429_bib0007","doi-asserted-by":"crossref","first-page":"ofz311","DOI":"10.1093\/ofid\/ofz311","article-title":"Babesiosis: a retrospective review of 38 cases in the upper midwest","volume":"6","author":"Fida","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0008","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF02561539","article-title":"Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis","volume":"27","author":"Goossens","year":"1999","journal-title":"Infection"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2021.115429_bib0009","doi-asserted-by":"crossref","first-page":"e99348","DOI":"10.1371\/journal.pone.0099348","article-title":"Co-infection of blacklegged ticks with Babesia microti andBorrelia burgdorferi is higher than expected and acquired from small mammal hosts","volume":"9","author":"Hersh","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0010","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1136\/jclinpath-2019-205822","article-title":"Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors","volume":"72","author":"Kerr","year":"2019","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0011","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/cid\/ciab050","article-title":"Clinical practice guidelines by the infectious diseases dociety of America (IDSA): 2020 guideline on diagnosis and management of babesiosis","volume":"72","author":"Krause","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0012","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1086\/339813","article-title":"Disease-specific diagnosis of coinfecting tickborne zoonoses: babesiosis, human granulocytic ehrlichiosis, and Lyme disease","volume":"34","author":"Krause","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0013","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1128\/CVI.00211-16","article-title":"Immunoglobulin M for acute infection: true or false?","volume":"23","author":"Landry","year":"2016","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.ttbdis.2020.101637","article-title":"Prevalence of single and coinfections of human pathogens in Ixodes ticks from five geographical regions in the United States, 2013-2019","author":"Lehane","year":"2021","journal-title":"Ticks Tick-Borne Dis"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0015","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.4269\/ajtmh.17-0146","article-title":"Risk factors for severe infection, hospitalization, and prolonged antimicrobial therapy in patients with babesiosis","volume":"97","author":"Mareedu","year":"2017","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0016","doi-asserted-by":"crossref","first-page":"2012","DOI":"10.1128\/jcm.25.10.2012-2013.1987","article-title":"Simultaneous transmission of Borrelia burgdorferi and Babesia microti by individual nymphal Ixodes dammini ticks","volume":"25","author":"Piesman","year":"1987","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0017","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0002-9343(02)01440-7","article-title":"Systemic symptoms without erythema migrans as the presenting picture of early Lyme disease","volume":"114","author":"Steere","year":"2003","journal-title":"Am J Med"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0018","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/ajcp\/107.2.142","article-title":"Positive Lyme disease serology in patients with clinical and laboratory evidenceof human granulocytic ehrlichiosis","volume":"107","author":"Wormser","year":"1997","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0019","doi-asserted-by":"crossref","first-page":"748","DOI":"10.3201\/eid2504.181509","article-title":"Co-infections in persons with early Lyme disease, New York, USA","volume":"25","author":"Wormser","year":"2019","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2021.115429_bib0020","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.diagmicrobio.2012.09.003","article-title":"Single-tier testing with the C6 peptide ELISA kit compared with two-tier testing for Lyme disease","volume":"75","author":"Wormser","year":"2013","journal-title":"Diagn Microbiol Infect Dis"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288932100122X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288932100122X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T09:56:21Z","timestamp":1760003781000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073288932100122X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S073288932100122X"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2021.115429","relation":{},"ISSN":["0732-8893"],"issn-type":[{"type":"print","value":"0732-8893"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Documentation of a false positive Lyme disease serologic test in a patient with untreated Babesia microti infection carries implications for accurately determining the frequency of Lyme disease coinfections","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2021.115429","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115429"}}