{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:33:26Z","timestamp":1760056406598,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002460","name":"Chung-Ang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002460","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2020R1A5A1018052"],"award-info":[{"award-number":["2020R1A5A1018052"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.diagmicrobio.2022.115768","type":"journal-article","created":{"date-parts":[[2022,7,16]],"date-time":"2022-07-16T03:39:45Z","timestamp":1657942785000},"page":"115768","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of simulated candidemia detection during prophylactic antifungal therapy"],"prefix":"10.1016","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4300-8964","authenticated-orcid":false,"given":"Yong Kwan","family":"Lim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oh Joo","family":"Kweon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Ryoun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae-Hyoung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi-Kyung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2022.115768_bib0001","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s13613-020-00755-8","article-title":"Epidemiology, clinical characteristics, and outcome of candidemia in critically ill patients in Germany: a single-center retrospective 10-year analysis","volume":"10","author":"Schroeder","year":"2020","journal-title":"Ann Intensive Care"},{"key":"10.1016\/j.diagmicrobio.2022.115768_bib0002","unstructured":"Invasive Candidiasis Statistics. 2022. Available from: https:\/\/www.cdc.gov\/fungal\/diseases\/candidiasis\/invasive\/statistics.html#eighteen. Accessed March 1, 2022."},{"key":"10.1016\/j.diagmicrobio.2022.115768_bib0003","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2147\/IDR.S80677","article-title":"Retrospective analysis of mortality and Candida isolates of 75 patients with candidemia: a single hospital experience","volume":"8","author":"Hirano","year":"2015","journal-title":"Infect Drug Resist"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2022.115768_bib0004","doi-asserted-by":"crossref","first-page":"4714","DOI":"10.1128\/JCM.41.10.4714-4717.2003","article-title":"Detection of simulated candidemia by the BACTEC 9240 system with plus aerobic\/F and anaerobic\/F blood culture bottles","volume":"41","author":"Horvath","year":"2003","journal-title":"J Clin Microbiol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2022.115768_bib0005","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/civ933","article-title":"Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America","volume":"62","author":"Pappas","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2022.115768_bib0006","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1128\/AAC.49.9.3640-3645.2005","article-title":"Delaying the empiric treatment of candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality","volume":"49","author":"Morrell","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2022.115768_bib0007","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.17652","article-title":"Comparison of antifungal prophylaxis drugs in patients with hematological disease or undergoing hematopoietic stem cell transplantation: a Systematic review and network meta-analysis","volume":"3","author":"Wang","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2022.115768_bib0008","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3109\/13693786.2010.512300","article-title":"Early treatment of candidemia in adults: a review","volume":"49","author":"Ostrosky-Zeichner","year":"2011","journal-title":"Med Mycol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2022.115768_bib0009","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1128\/AAC.50.2.632-638.2006","article-title":"Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infections","volume":"50","author":"Benjamin","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2022.115768_bib0010","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1128\/AAC.00868-08","article-title":"Pharmacokinetics and safety of caspofungin in neonates and infants less than 3 months of age","volume":"53","author":"S\u00e1ez-Llorens","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2022.115768_bib0011","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1590\/S1807-59322010000200017","article-title":"Fluconazole plasma concentration measurement by liquid chromatography for drug monitoring of burn patients","volume":"65","author":"Santos","year":"2010","journal-title":"Clinics"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2022.115768_bib0012","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1128\/AAC.00705-08","article-title":"Antifungal therapeutic drug monitoring: established and emerging indications","volume":"53","author":"Andes","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2022.115768_bib0013","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.2147\/IDR.S170706","article-title":"Trough concentration of itraconazole and its relationship with efficacy and safety: a systematic review and meta-analysis","volume":"11","author":"Zhang","year":"2018","journal-title":"Infect Drug Resistance"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2022.115768_bib0014","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s10156-013-0607-8","article-title":"Practice guidelines for therapeutic drug monitoring of voriconazole: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring","volume":"19","author":"Hamada","year":"2013","journal-title":"J Infection Chemotherapy"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2022.115768_bib0015","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1128\/am.19.6.955-959.1970","article-title":"Amphotericin B serum concentrations during therapy","volume":"19","author":"Fields","year":"1970","journal-title":"Appl Microbiol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2022.115768_bib0016","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0267491","article-title":"Considerations in evaluating equipment-free blood culture bottles: a short protocol for use in low-resource settings","volume":"17","author":"Ombelet","year":"2022","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2022.115768_bib0017","doi-asserted-by":"crossref","first-page":"3683","DOI":"10.1128\/JCM.02048-13","article-title":"Evaluation of bactec mycosis IC\/F and Plus Aerobic\/F blood culture bottles for detection of Candida in the presence of antifungal agents","volume":"51","author":"Kock","year":"2013","journal-title":"J Clin Microbiol"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2022.115768_bib0018","first-page":"251","article-title":"Comparative analysis of simulated candidemia using two different blood culture systems and the rapid identification of Candida albicans","volume":"41","author":"Park","year":"2011","journal-title":"Annals of Clin Laboratory Sci"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2022.115768_bib0019","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1128\/JCM.01958-10","article-title":"Comparison of BD Bactec Plus blood culture media to VersaTREK Redox blood culture media for detection of bacterial pathogens in simulated adult blood cultures containing therapeutic concentrations of antibiotics","volume":"49","author":"Miller","year":"2011","journal-title":"J Clin Microbiol"},{"year":"2020","series-title":"Performance standards for antifungal susceptibility testing of yeasts","key":"10.1016\/j.diagmicrobio.2022.115768_bib0020"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2022.115768_bib0021","doi-asserted-by":"crossref","first-page":"278","DOI":"10.3343\/alm.2019.39.3.278","article-title":"Comparison of clinical performance between BacT\/Alert Virtuo and BacT\/Alert 3D blood culture systems","volume":"39","author":"Kim","year":"2019","journal-title":"Annals Laboratory Medicine"},{"key":"10.1016\/j.diagmicrobio.2022.115768_bib0022","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3389\/fmicb.2019.00221","article-title":"In vitro Evaluation of BACT\/ALERT(R) VIRTUO(R), BACT\/ALERT 3D(R), and BACTEC FX automated blood culture systems for detection of microbial pathogens using simulated human blood samples","volume":"10","author":"Menchinelli","year":"2019","journal-title":"Front Microbiol"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2022.115768_bib0023","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00471-18","article-title":"In vitro evaluation of BacT\/Alert FA blood culture bottles and T2Candida assay for detection of candida in the presence of antifungals","volume":"56","author":"Beyda","year":"2018","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2022.115768_bib0024","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1128\/AAC.00945-09","article-title":"Effect of antifungal therapy timing on mortality in cancer patients with candidemia","volume":"54","author":"Taur","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2022.115768_bib0025","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1128\/JCM.01787-16","article-title":"Rapid detection and identification of Candidemia by direct blood culturing on solid medium by use of Lysis-Centrifugation method combined with matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)","volume":"55","author":"Idelevich","year":"2017","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2022.115768_bib0026","doi-asserted-by":"crossref","first-page":"103","DOI":"10.2217\/fmb.15.111","article-title":"T2MR and T2Candida: novel technology for the rapid diagnosis of candidemia and invasive candidiasis","volume":"11","author":"Pfaller","year":"2016","journal-title":"Future Microbiol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2022.115768_bib0027","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/s00277-017-3196-2","article-title":"Primary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)","volume":"97","author":"Mellinghoff","year":"2018","journal-title":"Ann Hematol"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2022.115768_bib0028","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1093\/cid\/cit006","article-title":"Finding the \"missing 50%\" of invasive candidiasis: how nonculture diagnostics will improve understanding of disease spectrum and transform patient care","volume":"56","author":"Clancy","year":"2013","journal-title":"Clin Infect Dis"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2022.115768_bib0029","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/vox.13071","article-title":"Impact of the COVID-19 pandemic on blood supply and demand in the WHO African Region","volume":"16","author":"Loua","year":"2021","journal-title":"Vox Sang"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2022.115768_bib0030","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s10096-014-2218-4","article-title":"Evaluation of blood culture media for the detection of fungi","volume":"34","author":"Nawrot","year":"2015","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889322001341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889322001341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T09:57:50Z","timestamp":1760003870000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889322001341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0732889322001341"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2022.115768","relation":{},"ISSN":["0732-8893"],"issn-type":[{"type":"print","value":"0732-8893"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of simulated candidemia detection during prophylactic antifungal therapy","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2022.115768","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115768"}}