{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T03:10:03Z","timestamp":1790478603664,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["17X(3)\/Adhoc\/68\/2022-ITR"],"award-info":[{"award-number":["17X(3)\/Adhoc\/68\/2022-ITR"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.diagmicrobio.2023.116046","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T11:32:37Z","timestamp":1690975957000},"page":"116046","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Isothermal amplification technology (IAT) for rapid diagnosis of Rickettsioses: scope, overview, existing evidence, and the way forward"],"prefix":"10.1016","volume":"107","author":[{"given":"Rashi","family":"Dixit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natarajan","family":"Gopalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujit Kumar","family":"Behera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0001","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3390\/tropicalmed5040165","article-title":"A brief history of the major rickettsioses in the Asia-Australia-Pacific region: a capstone review for the special issue of TMID","volume":"5","author":"Paris","year":"2020","journal-title":"Trop Med Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0002","doi-asserted-by":"crossref","first-page":"e01728","DOI":"10.1128\/JCM.01728-17","article-title":"A concise review of the epidemiology and diagnostics of rickettsioses: rickettsia and orientia spp","volume":"56","author":"Abdad","year":"2018","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0003","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1099\/00207713-51-6-2145","volume":"51","author":"Dumler","year":"2001","journal-title":"Int J Syst Evol Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0004","doi-asserted-by":"crossref","first-page":"e2021392","DOI":"10.4322\/acr.2021.392","article-title":"Rickettsia conorii infection with fatal complication","volume":"12","author":"Chugh","year":"2022","journal-title":"Autops Case Rep"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0005","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3390\/tropicalmed5020049","article-title":"Scrub typhus: historic perspective and current status of the worldwide presence of orientia species","volume":"5","author":"Richards","year":"2020","journal-title":"Trop Med Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0006","doi-asserted-by":"crossref","first-page":"e0009353","DOI":"10.1371\/journal.pntd.0009353","article-title":"Rickettsial infections: a blind spot in our view of neglected tropical diseases","volume":"15","author":"Salje","year":"2021","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0007","unstructured":"Increasing incidence of Rickettsial infection in patients of Pyrexia of Unknown Origin\u2014PubMed. Available at: https:\/\/pubmed.ncbi.nlm.nih.gov\/31331135\/ (accessed April 12), 2023."},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0008","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.idc.2007.08.002","article-title":"Fever of unknown origin due to rickettsioses","volume":"21","author":"Botelho-Nevers","year":"2007","journal-title":"Infect Dis Clin North Am"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0009","doi-asserted-by":"crossref","first-page":"387","DOI":"10.4103\/0255-0857.142241","article-title":"Possibility of scrub typhus in fever of unknown origin (FUO) cases: an experience from Rajasthan","volume":"32","author":"Bithu","year":"2014","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0010","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3390\/tropicalmed3010011","article-title":"Scrub typhus: no longer restricted to the tsutsugamushi triangle","volume":"3","author":"Jiang","year":"2018","journal-title":"Trop Med Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0011","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s40249-016-0186-x","article-title":"Clinical and paraclinical profile, and predictors of outcome in 90 cases of scrub typhus, Meghalaya, India","volume":"5","author":"Sivarajan","year":"2016","journal-title":"Infect Dis Poverty"},{"issue":"Suppl 1","key":"10.1016\/j.diagmicrobio.2023.116046_bib0012","doi-asserted-by":"crossref","first-page":"S52","DOI":"10.1086\/518147","article-title":"Pathogenic rickettsiae as bioterrorism agents","volume":"45","author":"Azad","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0013","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1574-695X.2011.00875.x","article-title":"Worldwide detection and identification of new and old rickettsiae and rickettsial diseases","volume":"64","author":"Richards","year":"2012","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0014","doi-asserted-by":"crossref","first-page":"537","DOI":"10.2217\/fmb.14.141","article-title":"Strategies for detecting rickettsiae and diagnosing rickettsial diseases","volume":"10","author":"Luce-Fedrow","year":"2015","journal-title":"Future Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0015","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.cll.2017.01.009","article-title":"Rickettsiae as emerging infectious agents","volume":"37","author":"Fang","year":"2017","journal-title":"Clin Lab Med"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0016","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.3390\/pathogens10101319","article-title":"An update on the laboratory diagnosis of rickettsia spp","volume":"10","author":"Stewart","year":"2021","journal-title":"Infection. Pathogens"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0017","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4103\/ijmm.IJMM_19_170","article-title":"Comparison of nested polymerase chain reaction and real-time polymerase chain reaction targeting 47kda gene for the diagnosis of scrub typhus","volume":"37","author":"Srinivasan","year":"2019","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0018","doi-asserted-by":"crossref","first-page":"677","DOI":"10.3390\/bios12090677","article-title":"Isothermal amplification technology for disease diagnosis","volume":"12","author":"Boonbanjong","year":"2022","journal-title":"Biosensors (Basel)"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0019","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.exppara.2013.03.031","article-title":"Simple, rapid, inexpensive platform for the diagnosis of malaria by loop mediated isothermal amplification (LAMP)","volume":"134","author":"Surabattula","year":"2013","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0020","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1186\/s12936-019-2979-4","article-title":"Ultrasensitive loop mediated isothermal amplification (US-LAMP) to detect malaria for elimination","volume":"18","author":"Mohon","year":"2019","journal-title":"Malar J"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0021","doi-asserted-by":"crossref","first-page":"11651","DOI":"10.1038\/s41598-020-68469-2","article-title":"Development of magnetic bead based sample extraction coupled polymerase spiral reaction for rapid on-site detection of Chikungunya virus","volume":"10","author":"Sharma","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0022","doi-asserted-by":"crossref","first-page":"e0138694","DOI":"10.1371\/journal.pone.0138694","article-title":"Colorimetric detection of dengue by single tube reverse-transcription-loop-mediated isothermal amplification","volume":"10","author":"Lau","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0023","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1073\/pnas.87.5.1874","article-title":"Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication","volume":"87","author":"Guatelli","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0024","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/nar\/20.7.1691","article-title":"Strand displacement amplification\u2014an isothermal, in vitro DNA amplification technique","volume":"20","author":"Walker","year":"1992","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0025","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/350091a0","article-title":"Nucleic acid sequence-based amplification","volume":"350","author":"Compton","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0026","doi-asserted-by":"crossref","first-page":"e63","DOI":"10.1093\/nar\/28.12.e63","article-title":"Loop-mediated isothermal amplification of DNA","volume":"28","author":"Notomi","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0027","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3390\/bios3010018","article-title":"Isothermal amplification methods for the detection of nucleic acids in microfluidic devices","volume":"3","author":"Zanoli","year":"2013","journal-title":"Biosensors (Basel)"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0028","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1039\/c0lc00666a","article-title":"Miniaturized isothermal nucleic acid amplification, a review","volume":"11","author":"Asiello","year":"2011","journal-title":"Lab Chip"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0029","first-page":"2172","article-title":"The sensitivity and specificity of loop-mediated isothermal amplification and PCR methods in detection of foodborne microorganisms: a systematic review and meta-analysis","volume":"50","author":"Sadeghi","year":"2021","journal-title":"Iran J Public Health"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.actatropica.2022.106691","article-title":"Development and evaluation of a visible reverse transcription-loop-mediated isothermal amplification (RT-LAMP) for the detection of Asian lineage ZIKV in field-caught mosquitoes","volume":"236","author":"Siriyasatien","year":"2022","journal-title":"Acta Trop"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0031","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1128\/CVI.05478-11","article-title":"Prospective evaluation of commercial antibody-based rapid tests in combination with a loop-mediated isothermal amplification PCR assay for detection of Orientia tsutsugamushi during the acute phase of scrub typhus infection","volume":"19","author":"Blacksell","year":"2012","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0032","doi-asserted-by":"crossref","first-page":"e0265760","DOI":"10.1371\/journal.pone.0265760","article-title":"Dengue fever as a reemerging disease in upper Egypt: diagnosis, vector surveillance and genetic diversity using RT-LAMP assay","volume":"17","author":"Gaber","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0033","doi-asserted-by":"crossref","first-page":"0114407","DOI":"10.1016\/j.jviromet.2021.114407","article-title":"Magnetic multiplex loop mediated isothermal amplification (MM-LAMP) technique for simultaneous detection of dengue and chikungunya virus","volume":"30","author":"Kumar","year":"2022","journal-title":"J Virol Methods"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0034","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/s12866-023-02806-z","article-title":"Rapid, sensitive, and specific detection of SARS-CoV-2 in nasopharyngeal swab samples of suspected patients using a novel one-step loop-mediated isothermal amplification (one-step LAMP) technique","volume":"23","author":"Khanizadeh","year":"2023","journal-title":"BMC Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0035","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1590\/s1678-9946202264057","article-title":"Evaluation of an in-house loop-mediated isothermal amplification for Mycobacterium tuberculosis detection in a remote reference laboratory","volume":"64","author":"Jekloh","year":"2022","journal-title":"Thailand. Rev Inst Med Trop Sao Paulo"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0036","doi-asserted-by":"crossref","first-page":"73","DOI":"10.4265\/bio.14.73","article-title":"The rapid detection of Salmonella from food samples by loop-mediated isothermal amplification (LAMP)","volume":"14","author":"Ueda","year":"2009","journal-title":"Biocontrol Sci"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0037","doi-asserted-by":"crossref","first-page":"e0010180","DOI":"10.1371\/journal.pntd.0010180","article-title":"Development of a simple, rapid, and sensitive diagnostic assay for enterotoxigenic E. coli and Shigella spp applicable to endemic countries","volume":"16","author":"Chakraborty","year":"2022","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0038","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.mimet.2019.04.010","article-title":"Development of isothermal amplification methods for rapid and sensitive detection of heat-labile enterotoxin producing Escherichia coli","volume":"161","author":"Liu","year":"2019","journal-title":"J Microbiol Methods"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0039","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.diagmicrobio.2011.08.021","article-title":"Multiplex isothermal helicase-dependent amplification assay for detection of Chlamydia trachomatis and Neisseria gonorrhoeae","volume":"71","author":"Doseeva","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0040","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1128\/JCM.43.5.2339-2344.2005","article-title":"Rapid and sensitive detection of severe acute respiratory syndrome coronavirus by rolling circle amplification","volume":"43","author":"Wang","year":"2005","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0041","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1039\/C4AN01954G","article-title":"Real-time detection of H5N1 influenza virus through hyperbranched rolling circle amplification","volume":"140","author":"Hamidi","year":"2015","journal-title":"Analyst"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0042","doi-asserted-by":"crossref","first-page":"e19","DOI":"10.1093\/nar\/gkn1014","article-title":"Sensitive isothermal detection of nucleic-acid sequence by primer generation-rolling circle amplification","volume":"37","author":"Murakami","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0043","doi-asserted-by":"crossref","first-page":"11902","DOI":"10.1038\/srep11902","article-title":"Rapid and sensitive isothermal detection of nucleic-acid sequence by multiple cross displacement amplification","volume":"5","author":"Wang","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0044","doi-asserted-by":"crossref","first-page":"812690","DOI":"10.3389\/fmicb.2021.812690","article-title":"Multiple cross displacement amplification combined with real-time polymerase chain reaction platform: a rapid, sensitive method to detect mycobacterium tuberculosis","volume":"12","author":"Jiao","year":"2021","journal-title":"Front Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0045","first-page":"2047","article-title":"Multiple cross displacement amplification combined with gold nanoparticle-based lateral flow biosensor for detection of vibrio parahaemolyticus","volume":"7","author":"Wang","year":"2016","journal-title":"Front Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0046","doi-asserted-by":"crossref","first-page":"e0230881","DOI":"10.1371\/journal.pone.0230881","article-title":"Establishment and application of isothermal amplification techniques for the detection of heat-stable I enterotoxin of enterotoxigenic Escherichia coli","volume":"15","author":"Zhai","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0047","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1128\/JCM.03298-13","article-title":"Improved detection limit in rapid detection of human enterovirus 71 and coxsackievirus A16 by a novel reverse transcription-isothermal multiple-self-matching-initiated amplification assay","volume":"52","author":"Ding","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0048","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/srep00246","article-title":"Cross priming amplification: mechanism and optimization for isothermal DNA amplification","volume":"2","author":"Xu","year":"2012","journal-title":"Sci Rep"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0049","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12941-021-00443-w","article-title":"Comparative evaluation of six nucleic acid amplification kits for SARS-CoV-2 RNA detection","volume":"20","author":"Wu","year":"2021","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0050","doi-asserted-by":"crossref","first-page":"106601","DOI":"10.1016\/j.mimet.2022.106601","article-title":"Molecular detection of \u201cCandidatus Rickettsia tarasevichiae\u201d by loop-mediated isothermal amplification (LAMP) of the ompA gene","volume":"202","author":"Xue","year":"2022","journal-title":"J Microbiol Methods"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0051","doi-asserted-by":"crossref","first-page":"e0010747","DOI":"10.1371\/journal.pntd.0010747","article-title":"Visual closed dumbbell-mediated isothermal amplification (CDA) for on-site detection of Rickettsia raoultii","volume":"16","author":"Gui","year":"2022","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0052","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/1471-2334-12-254","article-title":"Rapid, simple, and sensitive detection of the ompB gene of spotted fever group rickettsiae by loop-mediated isothermal amplification","volume":"12","author":"Pan","year":"2012","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0053","doi-asserted-by":"crossref","first-page":"e0192331","DOI":"10.1371\/journal.pone.0192331","article-title":"Development of a loop-mediated isothermal amplification (LAMP) assay for rapid screening of ticks and fleas for spotted fever group rickettsia","volume":"13","author":"Noden","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0054","doi-asserted-by":"crossref","first-page":"e00527","DOI":"10.1002\/mbo3.527","article-title":"Spotted fever group rickettsiae associated with ixodid ticks in wild environment in Southern Italy","volume":"7","author":"Raele","year":"2018","journal-title":"Microbiologyopen"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0055","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1128\/JCM.02786-13","article-title":"Loop-mediated isothermal amplification for Rickettsia typhi (the causal agent of murine typhus): problems with diagnosis at the limit of detection","volume":"52","author":"Dittrich","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0056","doi-asserted-by":"crossref","first-page":"119","DOI":"10.7883\/yoken.JJID.2015.579","article-title":"Development of a novel loop-mediated isothermal amplification (LAMP) assay for the detection of Rickettsia spp","volume":"70","author":"Hanaoka","year":"2017","journal-title":"Jpn J Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0057","doi-asserted-by":"crossref","first-page":"897","DOI":"10.3390\/diagnostics10110897","article-title":"Development of a multiplex loop-mediated isothermal amplification (LAMP) method for simultaneous detection of spotted fever group Rickettsiae and malaria parasites by dipstick DNA chromatography","volume":"10","author":"Moonga","year":"2020","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0058","doi-asserted-by":"crossref","first-page":"e0207811","DOI":"10.1371\/journal.pone.0207811","article-title":"Development of a rapid and visual detection method for Rickettsia rickettsii combining recombinase polymerase assay with lateral flow test","volume":"13","author":"Qi","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0059","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0003884","article-title":"Development of recombinase polymerase amplification assays for detection of Orientia tsutsugamushi or Rickettsia typhi","volume":"9","author":"Chao","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0060","doi-asserted-by":"crossref","first-page":"082","DOI":"10.4103\/JLP.JLP_148_18","article-title":"Evaluation of loop-mediated isothermal amplification assay for detection of scrub typhus in patients with acute febrile illness presenting to a Tertiary Care Center in Puducherry, India","volume":"11","author":"Karthikeyan","year":"2019","journal-title":"J Lab Physicians"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0061","doi-asserted-by":"crossref","first-page":"e0262302","DOI":"10.1371\/journal.pone.0262302","article-title":"Developing a multiplex loop-mediated isothermal amplification assay (LAMP) to determine severe fever with thrombocytopenia syndrome (SFTS) and scrub typhus","volume":"17","author":"Jang","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0062","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.trstmh.2008.04.040","article-title":"Simple, rapid and sensitive detection of Orientia tsutsugamushi by loop-isothermal DNA amplification","volume":"102","author":"Paris","year":"2008","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0063","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1373\/clinchem.2017.280230","article-title":"Rapid diagnosis of tick-borne illnesses by use of one-step isothermal nucleic acid amplification and bio-optical sensor detection","volume":"64","author":"Kim","year":"2018","journal-title":"Clin Chem"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0064","doi-asserted-by":"crossref","first-page":"e1307","DOI":"10.1371\/journal.pntd.0001307","article-title":"Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute Scrub Typhus infection","volume":"5","author":"Paris","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0065","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s13205-020-02389-w","article-title":"Diagnosis of scrub typhus: recent advancements and challenges","volume":"10","author":"Kala","year":"2020","journal-title":"3 Biotech"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0066","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3390\/bios13020202","article-title":"Advancements in CRISPR-Based biosensing for next-gen point of care diagnostic application","volume":"13","author":"Kumaran","year":"2023","journal-title":"Biosensors (Basel)"},{"issue":"18","key":"10.1016\/j.diagmicrobio.2023.116046_bib0067","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.3390\/ani12182413","article-title":"LAMP coupled CRISPR-Cas12a module for rapid, sensitive and visual detection of porcine circovirus 2","volume":"12","author":"Lei","year":"2022","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0068","doi-asserted-by":"crossref","first-page":"e0239822","DOI":"10.1128\/spectrum.02398-22","article-title":"Reverse transcription-loop-mediated isothermal amplification-CRISPR-Cas13a technology as a promising diagnostic tool for SARS-CoV-2","volume":"10","author":"Ortiz-Cartagena","year":"2022","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0069","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1038\/s41598-022-27133-7","article-title":"Rapid, multiplex detection of SARS-CoV-2 using isothermal amplification coupled with CRISPR-Cas12a","volume":"1313","author":"Figueiredo","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0070","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1080\/22221751.2020.1793689","article-title":"Next-generation pathogen diagnosis with CRISPR\/Cas-based detection methods","volume":"9","author":"Wang","year":"2020","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0071","first-page":"e00745","article-title":"SHERLOCK and DETECTR: CRISPR-cas systems as potential rapid diagnostic tools for emerging infectious diseases","volume":"5959","author":"Mustafa","year":"2021","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0072","doi-asserted-by":"crossref","first-page":"25722","DOI":"10.1073\/pnas.2010196117","article-title":"Ultrasensitive CRISPR-based diagnostic for field-applicable detection of plasmodium species in symptomatic and asymptomatic malaria","volume":"117","author":"Lee","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0073","article-title":"Disposable and low-cost pen-like sensor incorporating nucleic-acid amplification based lateral-flow assay for at-home tests of communicable pathogens","volume":"12","author":"Lu","year":"2022","journal-title":"Biosens Bioelectron X"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2023.116046_bib0074","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1007\/s00216-023-04650-6","article-title":"Integrating CRISPR\/Cas12a with strand displacement amplification for the ultrasensitive aptasensing of cadmium(II)","volume":"415","author":"Ma","year":"2023","journal-title":"Anal Bioanal Chem"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2023.340812","article-title":"An integrated dual-layer microfluidic platform for multiple respiratory viruses screening","volume":"1242","author":"Wang","year":"2023","journal-title":"Anal Chim Acta"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0076","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2022.340670","article-title":"Integrated slip valve-assisted fluidic chip coupling with CRISPR\/Cas12a system for nucleic acid analysis","volume":"1239","author":"Qian","year":"2023","journal-title":"Anal Chim Acta"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0077","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114377","article-title":"DropCRISPR: a LAMP-Cas12a based digital method for ultrasensitive detection of nucleic acid","volume":"211","author":"Wu","year":"2022","journal-title":"Biosens Bioelectron"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0078","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.vetpar.2015.02.008","article-title":"Development of loop-mediated isothermal amplification (LAMP) for detection of Babesia gibsoni infection in dogs","volume":"209","author":"Mandal","year":"2015","journal-title":"Vet Parasitol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0079","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.ijmmb.2021.06.011","article-title":"Evaluation of nested PCR and loop mediated isothermal amplification assay (LAMP) targeting 47 \u200bkDa gene of Orientia tsutsugamushi for diagnosis of scrub typhus","volume":"39","author":"Roy","year":"2021","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0080","doi-asserted-by":"crossref","first-page":"5456","DOI":"10.1128\/JCM.41.12.5456-5465.2003","article-title":"Gene Sequence-Based criteria for identification of new rickettsia isolates and description of rickettsia heilongjiangensis sp. nov","volume":"41","author":"Fournier","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0081","unstructured":"Rickettsial Diseases (Including Spotted Fever & Typhus Fever Rickettsioses, Scrub Typhus, Anaplasmosis, and Ehrlichioses) Chapter 4\u20132020 Yellow Book Travelers\u2019 Health | CDC n.d. New York: Oxford University Press. Available at:https:\/\/wwwnc.cdc.gov\/travel\/yellowbook\/2020\/travel-related-infectious-diseases\/rickettsial-including-spotted-fever-and-typhus-fever-rickettsioses-scrub-typhus-anaplasmosis-and-ehr (accessed April 21, 2023)."},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0082","doi-asserted-by":"crossref","first-page":"112","DOI":"10.4172\/2161-0703.1000112","article-title":"Isothermal amplification assay targeting the 47-Kda gene of orientia tsutsugamushi: a rapid and sensitive alternative to real-time PCR","volume":"1","author":"Huber","year":"2012","journal-title":"J Med Microb Diagn"},{"key":"10.1016\/j.diagmicrobio.2023.116046_bib0083","unstructured":"Taxonomy Browser\u2014NCBI\u2014NLM n.d. Available at: https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/taxonomy\/tree\/ (accessed April 21, 2023)."}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889323001566?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889323001566?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T09:59:46Z","timestamp":1760003986000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889323001566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":83,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S0732889323001566"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2023.116046","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Isothermal amplification technology (IAT) for rapid diagnosis of Rickettsioses: scope, overview, existing evidence, and the way forward","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2023.116046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116046"}}