{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T21:46:45Z","timestamp":1771710405081,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004006","name":"Istanbul University Scientific Research Projects Unit","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.diagmicrobio.2024.116262","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T17:26:37Z","timestamp":1710350797000},"page":"116262","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic Role of Opsonic Activity in Acinetobacter baumannii Ventilator-Associated Pneumonia"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7117-5102","authenticated-orcid":false,"given":"Asiye","family":"Karakulluk\u00e7u","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9140-2731","authenticated-orcid":false,"given":"Mustafa","family":"Akker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mert Ahmet","family":"Ku\u015fkucu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yal\u0131m","family":"Dikmen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6khan","family":"Ayg\u00fcn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116262_bib0001","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1097\/MS9.0000000000000836","article-title":"Ventilator associated pneumonia in intensive care unit patients: a systematic review","volume":"85","author":"Mumtaz","year":"2023","journal-title":"Ann Med Surg"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116262_bib0002","doi-asserted-by":"crossref","first-page":"49","DOI":"10.3390\/medicina55020049","article-title":"Ventilator-associated pneumonia due to drug-resistant Acinetobacter baumannii: risk factors and mortality relation with resistance profiles, and independent predictors of in-hospital mortality","volume":"55","author":"\u010ciginskien\u0117","year":"2019","journal-title":"Medicina"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116262_bib0003","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12890-021-01560-0","article-title":"Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care","volume":"21","author":"Al-Omari","year":"2021","journal-title":"BMC Pulm Med"},{"issue":"Suppl 1","key":"10.1016\/j.diagmicrobio.2024.116262_bib0004","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1086\/653062","article-title":"Ventilator-associated pneumonia: the clinical pulmonary infection score as a surrogate for diagnostics and outcome","volume":"51","author":"Zilberberg","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116262_bib0005","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.immuni.2016.02.026","article-title":"Phagocytosis: an immunobiologic process","volume":"44","author":"Gordon","year":"2016","journal-title":"Immunity"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2024.116262_bib0006","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","article-title":"APACHE II: a severity of disease classification system","volume":"13","author":"Knaus","year":"1985","journal-title":"Crit Care Med"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0007","unstructured":"Centers for Disease Control and Prevention. Ventilator-associated event (VAE) \u2013 For use in adult locations only [Internet]. Atlanta, GA: Centers for Disease Control and Prevention; January 2024. Available from:https:\/\/www.cdc.gov\/nhsn\/pdfs\/pscmanual\/10-vae_final.pdf. [Accessed July 7, 2023]."},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0008","series-title":"Bailey & scott's diagnostic microbiology","author":"Tille","year":"2017"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0009","series-title":"Performance standards for antimicrobial susceptibility testing","year":"2020"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2024.116262_bib0010","doi-asserted-by":"crossref","first-page":"917","DOI":"10.2105\/AJPH.23.9.917","article-title":"A study of the opsono-cytophagic power of the blood and allergic skin reaction in brucella infection and immunity in man","volume":"23","author":"Huddleson","year":"1933","journal-title":"Am J Public Health Nations Health"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2024.116262_bib0011","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/clinids\/11.5.827","article-title":"An experimental investigation of the r\u00f4le of the blood fluids in connection with phagocytosis. 1903","volume":"11","author":"Wright","year":"1989","journal-title":"Rev Infect Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116262_bib0012","doi-asserted-by":"crossref","first-page":"398","DOI":"10.7326\/0003-4819-89-3-398","article-title":"How do phagocytes eat?","volume":"89","author":"Stossel","year":"1978","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0013","first-page":"575","article-title":"A blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE\/DEAD\u00ae stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia","volume":"11","author":"Klinger-Strobel","year":"2016","journal-title":"Int J Nanomedicine"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0014","unstructured":"ORPEGEN Pharma. PHAGOTEST\u00ae Instructions, Version 7\/96, Catalog No. 10-0100. Heidelberg, Germany: ORPEGEN Pharma; n.d. Available from: https:\/\/citeseerx.ist.psu.edu\/document?repid=rep1&type=pdf&doi=56db28c8b6d934319e333e6961414e36ff7a198b. [Accessed July 7, 2023]."},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116262_bib0015","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0022-1759(94)00247-T","article-title":"Flow cytometric analysis of the granulocyte respiratory burst: a comparison study of fluorescent probes","volume":"178","author":"Vowells","year":"1995","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0016","series-title":"Discovering statistics using IBM SPSS statistics","author":"Field","year":"2018"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0017","unstructured":"Republic of Turkey, Ministry of Health. National Healthcare-Associated Infections Surveillance Network (USIHESA) Summary Report 2022 [in Turkish]. Ankara, Turkey: Ministry of Health; July 2023. Available from: https:\/\/hsgm.saglik.gov.tr\/depo\/birimler\/bulasici-hastaliklar-ve-erken-uyari-db\/Dokumanlar\/Raporlar\/USHIESA_OZET_RAPORU_2022.pdf. [Accessed March 7, 2024]."},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0018","article-title":"Investigation of effect of the colistin loading dosage on the clinical, microbiological, and laboratory results in Acinetobacter baumannii ventilator-associated pneumonia \/pneumonia","volume":"2022","author":"Keski","year":"2022","journal-title":"Int J Clin Pract"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116262_bib0019","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jiph.2023.01.004","article-title":"A two-year retrospective study of multidrug-resistant Acinetobacter baumannii respiratory infections in critically Ill patients: clinical and microbiological findings","volume":"16","author":"Hafiz","year":"2023","journal-title":"J Infect Public Health"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0020","doi-asserted-by":"crossref","DOI":"10.21037\/jeccm-22-32","article-title":"Diagnosis, management and treatment of nosocomial pneumonia in ICU: a narrative review","volume":"6","author":"Bussini","year":"2022","journal-title":"J Emerg Crit Care Med"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116262_bib0021","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1097\/01.ccm.0000435665.07446.50","article-title":"EU-VAP study investigators. Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients","volume":"42","author":"Blot","year":"2014","journal-title":"Crit Care Med"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2024.116262_bib0022","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/S1473-3099(13)70081-1","article-title":"Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies","volume":"13","author":"Melsen","year":"2013","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2024.116262_bib0023","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1378\/chest.117.4_suppl_2.186S","article-title":"Epidemiolgy of ventilator-associated pneumonia","volume":"117","author":"Craven","year":"2000","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116262_bib0024","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11908-018-0609-x","article-title":"Resistance trends and treatment options in gram-negative ventilator-associated pneumonia","volume":"20","author":"Rhodes","year":"2018","journal-title":"Curr Infect Dis Rep"},{"issue":"6s","key":"10.1016\/j.diagmicrobio.2024.116262_bib0025","first-page":"45","article-title":"Global spread of drug-resistant Acinetobacter baumannii: molecular epidemiology and management of antimicrobial resistance","volume":"14","author":"Durante-Mangoni","year":"2019","journal-title":"Future Microbiol"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2024.116262_bib0026","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.3390\/healthcare10112210","article-title":"Molecular characterization and antibiogram of Acinetobacter baumannii clinical isolates recovered from the patients with ventilator-associated pneumonia","volume":"10","author":"Saleem","year":"2022","journal-title":"Healthcare (Basel)"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116262_bib0027","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00134-022-06898-5","article-title":"Bronchoscopy for diagnosis of ventilator-associated pneumonia","volume":"49","author":"Martin-Loeches","year":"2023","journal-title":"Intensive Care Med"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116262_bib0028","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0891-5520(03)00075-8","article-title":"Diagnosis of hospital-acquired pneumonia: postmortem studies","volume":"17","author":"Nseir","year":"2003","journal-title":"Infect Dis Clin North Am"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116262_bib0029","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1007\/s00134-020-06036-z","article-title":"Diagnosis of ventilator-associated pneumonia in critically ill adult patients-a systematic review and meta-analysis","volume":"46","author":"Fernando","year":"2020","journal-title":"Intensive Care Med"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116262_bib0030","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ajic.2015.12.032","article-title":"Differentiating infectious and noninfectious ventilator-associated complications: a new challenge","volume":"44","author":"O'Horo","year":"2016","journal-title":"Am J Infect Control"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889324000919?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889324000919?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T23:16:10Z","timestamp":1716592570000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889324000919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S0732889324000919"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2024.116262","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic Role of Opsonic Activity in Acinetobacter baumannii Ventilator-Associated Pneumonia","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2024.116262","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116262"}}