{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T17:09:54Z","timestamp":1763831394078,"version":"3.37.3"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100015792","name":"Shanghai City Pudong New Area People's Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015792","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019978","name":"Shanghai Pudong New Area Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019978","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.diagmicrobio.2024.116299","type":"journal-article","created":{"date-parts":[[2024,4,20]],"date-time":"2024-04-20T03:33:00Z","timestamp":1713583980000},"page":"116299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Serological evaluation of recombinant protein antigen Tp0608 for the diagnosis of syphilis"],"prefix":"10.1016","volume":"109","author":[{"given":"Yingying","family":"Lu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingting","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0001","doi-asserted-by":"crossref","first-page":"1002342","DOI":"10.3389\/fpubh.2022.1002342","article-title":"Prevalence of syphilis among people living with HIV and its implication for enhanced coinfection monitoring and management in China: A meta-analysis","volume":"10","author":"Wu","year":"2022","journal-title":"Front Public Health"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0002","doi-asserted-by":"crossref","first-page":"966813","DOI":"10.3389\/fpubh.2022.966813","article-title":"Development and comparison of predictive models for sexually transmitted diseases-AIDS, gonorrhea, and syphilis in China, 2011-2021","volume":"10","author":"Zhu","year":"2022","journal-title":"Front Public Health"},{"issue":"26","key":"10.1016\/j.diagmicrobio.2024.116299_bib0003","doi-asserted-by":"crossref","first-page":"476","DOI":"10.46234\/ccdcw2020.123","article-title":"Screening and Treatment of Syphilis for Pregnant Women - China, 2011-2018","volume":"2","author":"Qiao","year":"2020","journal-title":"China CDC Wkly"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0004","doi-asserted-by":"crossref","unstructured":"Runina AV, Starovoitova AS, Deryabin DG et al. Evaluation of the recombinant protein Tp0965 of Treponema Pallidum as Perspective Antigen for the Improved Serological Diagnosis of Syphilis]. 2016;(2):109-113.","DOI":"10.15690\/vramn653"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0005","doi-asserted-by":"crossref","first-page":"e24635","DOI":"10.1002\/jcla.24635","article-title":"Assessment of recombinant antigens Tp0100 and Tp1016 of Treponema pallidum for serological diagnosis of syphilis","volume":"36","author":"Chen","year":"2022","journal-title":"J Clin Lab Anal"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0006","doi-asserted-by":"crossref","unstructured":"Aleksey Kubanov, Anastassia Runina, and Dmitry Deryabin Novel Treponema pallidum Recombinant Antigens for Syphilis Diagnostics: Current Status and Future Prospects 2017;10: 1436080-92.","DOI":"10.1155\/2017\/1436080"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2024.116299_bib0007","doi-asserted-by":"crossref","first-page":"e0010063","DOI":"10.1371\/journal.pntd.0010063","article-title":"Shrestha Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar","volume":"15","author":"Lieberman","year":"2021","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0008","unstructured":"Regulatory documents-National Health Commission of the People's Republic of China, http:\/\/www.nhc.gov.cn\/wjw\/s9491\/201803\/5103a5425f9e47d29b91de38434b7f74.shtml."},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0009","doi-asserted-by":"crossref","unstructured":"Ling Yang, Yu Fu, Si Li, et al Analysis of Treponema pallidum DNA and CXCL13 in Cerebrospinal Fluid in HIV-Negative Syphilis Patients Infection and Drug Resistance 2022:15 7791\u20137798.","DOI":"10.2147\/IDR.S394581"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2024.116299_bib0010","doi-asserted-by":"crossref","first-page":"e22890","DOI":"10.1002\/jcla.22890","article-title":"PCR detection for syphilis diagnosis: Status and prospects","volume":"33","author":"Zhou","year":"2019","journal-title":"J Clin Lab Anal"},{"year":"2017","series-title":"Koneman's color atlas and textbook of diagnostic microbiology","author":"Procop","key":"10.1016\/j.diagmicrobio.2024.116299_bib0011"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2024.116299_bib0012","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1097\/OLQ.0000000000001386","article-title":"Limited Utility of Reverse Algorithm Syphilis Testing in HIV Clinic Among Men Who Have Sex With Men","volume":"48","author":"Dionne-Odom","year":"2021","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0013","unstructured":"Xinyu Wang, Yanhai Zhang, Kai Cui Establishment of measurement threshold and comparison of results for detection of Treponema pallidum specific antibody by Siemens ADVIACentaur XP chemiluminescent immunoanalyzer Sheng Wu Gong Cheng Xue Bao. 2020;36(8):1672-1678."},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0014","series-title":"Manual of clinical microbiology","first-page":"1083","article-title":"Treponema and Brachyspira. Human Host-Associated Spirochetes","author":"Aguero-Se\u00f1a","year":"2019"},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0015","first-page":"1436080","article-title":"Novel Treponema pallidum recombinant antigens for syphilis diagnostics:current status and future prospects","author":"Kubanov","year":"2017","journal-title":"Biomed Res Int"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116299_bib0016","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1093\/cid\/ciy558","article-title":"Fakile,2 Joan M. Chow Performance of treponemal tests for the diagnosis of syphilis","volume":"68","author":"Park","year":"2019","journal-title":"Clin Infect Dis"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116299_bib0017","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1159\/000531341","article-title":"The diagnostic performance of laboratory tests of neurosyphilis: a systematic review and network meta-analysis","volume":"86","author":"Ding","year":"2023","journal-title":"Eur Neurol."},{"key":"10.1016\/j.diagmicrobio.2024.116299_bib0018","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/lam.12554","article-title":"Diagnostic value of recombinant Tp0821 protein in serodiagnosis for syphilis","volume":"62","author":"Xie","year":"2016","journal-title":"Lett Appl Microbiol"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2024.116299_bib0019","doi-asserted-by":"crossref","first-page":"e0242386","DOI":"10.1371\/journal.pone.0242386","article-title":"Vasconcelos LCM Correction: Performance of Treponema pallidum recombinant proteins in the serological diagnosis of syphilis","volume":"15","author":"Silva","year":"2020","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116299_bib0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008812","article-title":"Romeis E et al Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum","volume":"15","author":"Haynes","year":"2021","journal-title":"PLoS Negl Trop Dis"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2024.116299_bib0021","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1093\/infdis\/jis459","article-title":"Significance of isolated reactive treponemal chemiluminescence immunoassay results","volume":"207","author":"Hunter","year":"2013","journal-title":"J Infect Diseases"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116299_bib0022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/femspd\/ftx122","article-title":"Screening and identification of immunoactive FlaB protein fragments of Treponema pallidum for the serodiagnosis of syphilis","volume":"76","author":"Tan","year":"2018","journal-title":"Pathog Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116299_bib0023","first-page":"419","article-title":"Lais Gon\u00e7alves Ortolani Miranda Tp0684, Tp0750, and Tp0792 Recombinant Proteins as Antigens for the Serodiagnosis of Syphilis Indian","volume":"62","author":"Queiroz","year":"2022","journal-title":"J Microbiol"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889324001287?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889324001287?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T23:16:37Z","timestamp":1716592597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889324001287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S0732889324001287"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2024.116299","relation":{},"ISSN":["0732-8893"],"issn-type":[{"type":"print","value":"0732-8893"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Serological evaluation of recombinant protein antigen Tp0608 for the diagnosis of syphilis","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2024.116299","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116299"}}