{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:54:50Z","timestamp":1787313290741,"version":"build-2736575974"},"reference-count":61,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Minas Gerais State Foundation of Support to the Research","doi-asserted-by":"publisher","award":["RED-0067-23"],"award-info":[{"award-number":["RED-0067-23"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Minas Gerais State Foundation of Support to the Research","doi-asserted-by":"publisher","award":["APQ-02167-21"],"award-info":[{"award-number":["APQ-02167-21"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["402417\/2023-2"],"award-info":[{"award-number":["402417\/2023-2"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.diagmicrobio.2024.116338","type":"journal-article","created":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T16:25:36Z","timestamp":1714753536000},"page":"116338","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["A recombinant chimeric antigen constructed with B-cell epitopes from Mycobacterium leprae hypothetical proteins is effective for the diagnosis of leprosy"],"prefix":"10.1016","volume":"109","author":[{"given":"B\u00e1rbara P.N.","family":"Assis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana T.","family":"Chaves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela P.","family":"Lage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana M.","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabela A.G.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel S.B.","family":"C\u00e2mara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila S.","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00edvian T.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Ludolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Laura G.","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o A.","family":"Oliveira-da-Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grasiele S.V.","family":"Tavares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexsandro S.","family":"Galdino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A.","family":"Ch\u00e1vez-Fumagalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo A.","family":"Machado-de-\u00c1vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myron","family":"Christodoulides","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise U.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edlian L.","family":"Bueno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo T.","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo A.F.","family":"Coelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoel Ot\u00e1vio","family":"da Costa Rocha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0001","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.actatropica.2016.07.019","article-title":"Spatial and temporal epidemiology of Mycobacterium leprae infection among leprosy patients and household contacts of an endemic region in Southeast Brazil","volume":"163","author":"Nicchio","year":"2016","journal-title":"Acta Trop"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0002","first-page":"39","article-title":"Leprosy (Hansen's disease): an update and review","volume":"120","author":"Gilmore","year":"2023","journal-title":"Mo Med"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0003","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1080\/21505594.2022.2141987","article-title":"Pathogenicity and virulence of Mycobacterium leprae","volume":"13","author":"Sugawara-Mikami","year":"2022","journal-title":"Virulence"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0004","doi-asserted-by":"crossref","first-page":"8868","DOI":"10.1038\/s41598-017-07803-7","article-title":"Field-friendly serological tests for determination of M. leprae-specific antibodies","volume":"7","author":"Van Hooij","year":"2017","journal-title":"Sci Rep."},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0005","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ijid.2022.01.009","article-title":"Leprosy relapse: a retrospective study on epidemiologic, clinical, and therapeutic aspects at a Brazilian referral center","volume":"118","author":"Nascimento","year":"2022","journal-title":"Int J Infect Dis"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116338_bib0006","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00403-008-0857-y","article-title":"Leprosy: diagnostic and control challenges for a worldwide disease","volume":"300","author":"Goulart","year":"2008","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2020.104475","article-title":"Mycobacterium leprae: pathogenesis, diagnosis, and treatment options","volume":"149","author":"Mungroo","year":"2020","journal-title":"Microb Pathog"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2024.116338_bib0008","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.ad.2012.03.003","article-title":"An update: definition, pathogenesis, classification, diagnosis, and treatment","volume":"104","author":"Eichelmann","year":"2013","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0009","series-title":"Guideline for the Diagnosis, Treatment and Prevention of Leprosy","year":"2018"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116338_bib0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0007284","article-title":"Development and evaluation of a droplet digital PCR assay for the diagnosis of paucibacillary leprosy in skin biopsy specimens","volume":"13","author":"Cheng","year":"2019","journal-title":"PLoS Negl Trop Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0011","doi-asserted-by":"crossref","first-page":"e2655","DOI":"10.1371\/journal.pntd.0002655","article-title":"PCR-based techniques for leprosy diagnosis: from the laboratory to the clinic","volume":"8","author":"Martinez","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116338_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.diagmicrobio.2021.115337","article-title":"Sensitivity and specificity of multibacillary and paucibacillary leprosy laboratory tests: a systematic review and meta-analysis","volume":"100","author":"Torres","year":"2021","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0013","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3390\/tropicalmed3040107","article-title":"Polymerase Chain Reaction (PCR) as a potential point of care laboratory test for leprosy diagnosis-a systematic review","volume":"3","author":"Tatipally","year":"2018","journal-title":"Trop Med Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0014","doi-asserted-by":"crossref","DOI":"10.1590\/0037-8682-0197-2020","article-title":"Prospects for new leprosy diagnostic tools, a narrative review considering ELISA and PCR assays","volume":"53","author":"Gama","year":"2020","journal-title":"Rev Soc Bras Med Trop"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2024.116338_bib0015","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1128\/CVI.00148-08","article-title":"Serological diagnosis of leprosy in patients in Vietnam by enzyme-linked immunosorbent assay with Mycobacterium leprae-derived major membrane protein II","volume":"15","author":"Kai","year":"2008","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0016","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/35059006","article-title":"Massive gene decay in the leprosy bacillus","volume":"409","author":"Cole","year":"2001","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116338_bib0017","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005598","article-title":"Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases","volume":"11","author":"Stefani","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0018","first-page":"382","article-title":"Evidence for species-specific lipid antigens in Mycobacterium leprae","volume":"48","author":"Brennan","year":"1980","journal-title":"Int J Lepr Other Mycobact Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116338_bib0019","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1128\/jb.147.3.728-735.1981","article-title":"A novel phenolic glycolipid from Mycobacterium leprae possibly involved in immunogenicity and pathogenicity","volume":"147","author":"Hunter","year":"1981","journal-title":"J Bacteriol"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116338_bib0020","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.diagmicrobio.2015.07.012","article-title":"Detection of antibodies to both M. leprae PGL-I and MMP-II to recognize leprosy patients at an early stage of disease progression","volume":"83","author":"Wang","year":"2015","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116338_bib0021","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.diagmicrobio.2014.02.006","article-title":"A rapid ELISA for the diagnosis of MB leprosy based on complementary detection of antibodies against a novel protein-glycolipid conjugate","volume":"79","author":"Duthie","year":"2014","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116338_bib0022","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/trstmh\/trz089","article-title":"Evaluation of antibody detection against the NDO-BSA, LID-1 and NDO-LID antigens as confirmatory tests to support the diagnosis of leprosy in Yunnan province, southwest China","volume":"114","author":"Jian","year":"2020","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.imbio.2019.11.001","article-title":"PGL-1 and LID-1 antibody levels in HIV-infected and HIV-uninfected individuals in a Hansen's disease (leprosy) endemic area of Brazil","volume":"225","author":"Madureira","year":"2020","journal-title":"Immunobiology"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2024.116338_bib0024","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004934","article-title":"Identifying leprosy and those at risk of developing leprosy by detection of antibodies against LID-1 and LID-NDO","volume":"10","author":"Amorim","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0025","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/s12879-018-3653-0","article-title":"Performance of serological tests PGL1 and NDO-LID in the diagnosis of leprosy in a reference Center in Brazil","volume":"19","author":"Leturiondo","year":"2019","journal-title":"BMC Infect Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0026","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1365-3083.2012.02677.x","article-title":"Advances in proteomics of Mycobacterium leprae","volume":"75","author":"Parkash","year":"2012","journal-title":"Scand J Immunol"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2024.116338_bib0027","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1128\/IAI.00617-08","article-title":"Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus","volume":"77","author":"Glowalla","year":"2009","journal-title":"Infect Immun"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0028","doi-asserted-by":"crossref","first-page":"e1430","DOI":"10.1371\/journal.pntd.0001430","article-title":"Identification of proteins in promastigote and amastigote-like Leishmania using an immunoproteomic approach","volume":"6","author":"Coelho","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2024.116338_bib0029","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1128\/CVI.00465-15","article-title":"Proteins selected in Leishmania (Viannia) Braziliensis by an immunoproteomic approach with potential Serodiagnosis applications for Tegumentary Leishmaniasis","volume":"22","author":"Duarte","year":"2015","journal-title":"Clin Vaccine Immunol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0030","article-title":"Identification of highly expressed plasmodium vivax proteins from clinical isolates using proteomics","volume":"12","author":"Venkatesh","year":"2018","journal-title":"Proteomics Clin Appl"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2024.116338_bib0031","doi-asserted-by":"crossref","first-page":"ftw110","DOI":"10.1093\/femspd\/ftw110","article-title":"Excavating the surface-associated and secretory proteome of Mycobacterium leprae for identifying vaccines and diagnostic markers relevant immunodominant epitopes","volume":"74","author":"Rana","year":"2016","journal-title":"Pathog Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0032","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3390\/proteomes9010007","article-title":"Insights into Mycobacterium leprae proteomics and biomarkers-an overview","volume":"9","author":"Gautam","year":"2021","journal-title":"Proteomes"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2024.116338_bib0033","doi-asserted-by":"crossref","first-page":"e2524","DOI":"10.1371\/journal.pntd.0002524","article-title":"Identification of strain-specific B-cell epitopes in Trypanosoma cruzi using genome-scale epitope prediction and high-throughput immunoscreening with peptide arrays","volume":"7","author":"Mendes","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2024.116338_bib0034","doi-asserted-by":"crossref","first-page":"2942","DOI":"10.1002\/pmic.200400945","article-title":"Continued proteomic analysis of Mycobacterium leprae subcellular fractions","volume":"4","author":"Marques","year":"2004","journal-title":"Proteomics"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2024.116338_bib0035","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1002\/pmic.200700971","article-title":"Deciphering the proteomic profile of Mycobacterium leprae cell envelope","volume":"8","author":"Marques","year":"2008","journal-title":"Proteomics"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2024.116338_bib0036","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1016\/j.jprot.2011.01.004","article-title":"A quantitative view on Mycobacterium leprae antigens by proteomics","volume":"74","author":"Wiker","year":"2011","journal-title":"J Proteomics"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2024.116338_bib0037","doi-asserted-by":"crossref","first-page":"4782","DOI":"10.4049\/jimmunol.1103452","article-title":"New biomarkers with relevance to leprosy diagnosis applicable in areas hyperendemic for leprosy","volume":"188","author":"Geluk","year":"2012","journal-title":"J Immunol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0038","doi-asserted-by":"crossref","first-page":"543","DOI":"10.47276\/lr.87.4.543","article-title":"Difficult diagnosis and challenging treatment \u2013 a report on leprosy","volume":"87","author":"Marahatta","year":"2016","journal-title":"Lepr Rev"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116338_bib0039","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4103\/idoj.IDOJ_260_18","article-title":"Recent laboratory advances in diagnostics and monitoring response to treatment in leprosy","volume":"10","author":"Sengupta","year":"2019","journal-title":"Indian Dermatol Online J"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0040","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.3389\/fimmu.2020.01811","article-title":"Household contacts of leprosy patients in endemic areas display a specific innate immunity profile","volume":"11","author":"Van Hooij","year":"2020","journal-title":"Front Immunol"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0041","doi-asserted-by":"crossref","DOI":"10.1590\/0074-02760220317","article-title":"Accuracy of rapid point-of-care serological tests for leprosy diagnosis: a systematic review and meta-analysis","volume":"117","author":"Romero","year":"2022","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2024.116338_bib0042","first-page":"255","article-title":"Classification of leprosy according to immunity. A five-group system","volume":"34","author":"Ridley","year":"1966","journal-title":"Int J Lepr Other Mycobact Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2024.116338_bib0043","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jaad.2019.12.080","article-title":"Leprosy: clinical aspects and diagnostic techniques","volume":"83","author":"Maymone","year":"2020","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116338_bib0044","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1574-6968.2007.00754.x","article-title":"Evaluation of major membrane protein-II as a tool for serodiagnosis of leprosy","volume":"272","author":"Maeda","year":"2007","journal-title":"FEMS Microbiol Lett"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2024.116338_bib0045","doi-asserted-by":"crossref","DOI":"10.1590\/0074-02760170467","article-title":"Utility of immunoglobulin isotypes against LID-1 and NDO-LID for, particularly IgG1, confirming the diagnosis of multibacillary leprosy","volume":"113","author":"Mar\u00e7al","year":"2018","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2024.116338_bib0046","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.jiph.2019.12.011","article-title":"Diagnostic accuracy of tests using recombinant protein antigens of Mycobacterium leprae for leprosy: a systematic review","volume":"13","author":"Oliveira","year":"2020","journal-title":"J Infect Public Health"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0047","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1186\/1471-2334-13-497","article-title":"Development of a quantitative rapid diagnostic test for multibacillary leprosy using smart phone technology","volume":"13","author":"Vaz","year":"2013","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0048","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s12879-015-0962-4","article-title":"Antigen-specific assessment of the immunological status of various groups in a leprosy endemic region","volume":"15","author":"Fabri","year":"2015","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0049","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1051\/parasite\/2023011","article-title":"A systematic review of peptide-based serological tests for the diagnosis of leishmaniasis","volume":"30","author":"Pagniez","year":"2023","journal-title":"Parasite"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0050","doi-asserted-by":"crossref","first-page":"914","DOI":"10.2174\/1389203717666160724203746","article-title":"Peptide biomarkers: Exploring the diagnostic aspect","volume":"18","author":"Mahendru","year":"2017","journal-title":"Curr Protein Pept Sci"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0051","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2174\/1389203033487126","article-title":"Synthetic peptides in the diagnosis of systemic autoimmune diseases","volume":"4","author":"Fournel","year":"2003","journal-title":"Curr Protein Pept Sci"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0052","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1007\/s00253-014-6168-7","article-title":"Linear B-cell epitope mapping of MAPK3 and MAPK4 from Leishmania braziliensis: implications for the serodiagnosis of human and canine leishmaniasis","volume":"99","author":"Menezes-Souza","year":"2015","journal-title":"Appl Microbiol Biotechnol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116338_bib0053","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1128\/CMR.19.2.338-381.2006","article-title":"The continuing challenges of leprosy","volume":"19","author":"Scollard","year":"2006","journal-title":"Clin Microbiol Rev"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2024.116338_bib0054","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1590\/S0074-02762012000800015","article-title":"Leprosy exposure, infection and disease: a 25-year surveillance study of leprosy patient contacts","volume":"107","author":"Sarno","year":"2012","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2024.116338_bib0055","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.imbio.2019.05.002","article-title":"Immunological biomarkers of subclinical infection in household contacts of leprosy patients","volume":"224","author":"Queiroz","year":"2019","journal-title":"Immunobiology"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2024.116338_bib0056","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1001\/jamadermatol.2020.0653","article-title":"Incidence of and factors associated with leprosy among household contacts of patients with leprosy in Brazil","volume":"156","author":"Teixeira","year":"2020","journal-title":"JAMA Dermatol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2024.116338_bib0057","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1128\/CVI.00419-12","article-title":"Gene expression profile and immunological evaluation of unique hypothetical unknown proteins of Mycobacterium leprae by using quantitative real-time PCR","volume":"20","author":"Kim","year":"2013","journal-title":"Clin Vaccine Immunol"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2024.116338_bib0058","doi-asserted-by":"crossref","first-page":"7930","DOI":"10.4049\/jimmunol.175.12.7930","article-title":"Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy","volume":"175","author":"Spencer","year":"2005","journal-title":"J Immunol"},{"key":"10.1016\/j.diagmicrobio.2024.116338_bib0059","doi-asserted-by":"crossref","first-page":"8","DOI":"10.4103\/0972-9062.179209","article-title":"Laboratory diagnosis of human visceral leishmaniasis","volume":"53","author":"Sakkas","year":"2016","journal-title":"J Vector Borne Dis"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2024.116338_bib0060","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s12192-019-01016-9","article-title":"Protein quality control machinery in intracellular protozoan parasites: hopes and challenges for therapeutic targeting","volume":"24","author":"Anas","year":"2019","journal-title":"Cell Stress Chaperones"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2024.116338_bib0061","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.1007\/s00436-021-07342-1","article-title":"ChimLeish, a new recombinant chimeric protein evaluated as a diagnostic and prognostic marker for visceral leishmaniasis and human immunodeficiency virus coinfection","volume":"120","author":"Galvani","year":"2021","journal-title":"Parasitol Res"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889324001676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889324001676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T00:41:40Z","timestamp":1731890500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889324001676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["S0732889324001676"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2024.116338","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A recombinant chimeric antigen constructed with B-cell epitopes from Mycobacterium leprae hypothetical proteins is effective for the diagnosis of leprosy","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2024.116338","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116338"}}