{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T19:10:55Z","timestamp":1771269055655,"version":"3.50.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T00:00:00Z","timestamp":1741564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.diagmicrobio.2025.116795","type":"journal-article","created":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T06:35:24Z","timestamp":1741502124000},"page":"116795","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Non-invasive diagnosis of pulmonary tuberculosis and predictive potential for treatment outcomes via miR-146a and miR-155 levels"],"prefix":"10.1016","volume":"112","author":[{"given":"Li-Huan","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Li","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0001","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s43465-020-00326-w","article-title":"The role of cartridge-based nucleic acid amplification test (CBNAAT), line probe assay (LPA), liquid culture, acid-fast Bacilli (AFB) smear and histopathology in the diagnosis of osteoarticular tuberculosis","volume":"55","author":"Abhimanyu","year":"2021","journal-title":"Indian J Orthop"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0002","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2023-012297","article-title":"A costing framework to compare tuberculosis infection tests","volume":"8","author":"Brumwell","year":"2023","journal-title":"BMJ Glob Health"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0003","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.3855\/jidc.16721","article-title":"Association between active pulmonary tuberculosis and miRNA-146a: a preliminary study from Serbia","volume":"16","author":"Buha","year":"2022","journal-title":"J Infect Dev Ctries"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0004","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/nri.2017.69","article-title":"Heterogeneity in tuberculosis","volume":"17","author":"Cadena","year":"2017","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0005","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1093\/jpids\/piaa019","volume":"10","author":"Dayal","year":"2021","journal-title":"J Pediatric Infect Dis Soc"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0006","doi-asserted-by":"crossref","first-page":"S108","DOI":"10.1093\/infdis\/jiz356","article-title":"Guidance for studies evaluating the accuracy of biomarker-based nonsputum tests to diagnose tuberculosis","volume":"220","author":"Drain","year":"2019","journal-title":"J Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006790","article-title":"Mycobacterium tuberculosis-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells","volume":"14","author":"Etna","year":"2018","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0008","doi-asserted-by":"crossref","first-page":"4246","DOI":"10.1128\/JCM.05459-11","article-title":"Circulating microRNAs in patients with active pulmonary tuberculosis","volume":"49","author":"Fu","year":"2011","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0009","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.ijmyco.2013.04.006","article-title":"Alteration of human macrophages microRNA expression profile upon infection with mycobacterium tuberculosis","volume":"2","author":"Furci","year":"2013","journal-title":"Int J Mycobacteriol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0010","doi-asserted-by":"crossref","first-page":"625","DOI":"10.3855\/jidc.9601","article-title":"Mantoux test revisited: variability in reading tuberculin test in pediatric population","volume":"12","author":"Goel","year":"2018","journal-title":"J Infect Dev Ctries"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0011","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S1473-3099(21)00145-6","article-title":"Comparison of three tests for latent tuberculosis infection in high-risk people in the USA: an observational cohort study","volume":"22","author":"Ho","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0012","doi-asserted-by":"crossref","first-page":"7102","DOI":"10.3892\/mmr.2015.4250","article-title":"MiR-155 is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO3","volume":"12","author":"Huang","year":"2015","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0013","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1017\/S0022029918000122","article-title":"Milk microRNA-146a as a potential biomarker in bovine tuberculosis","volume":"85","author":"Iannaccone","year":"2018","journal-title":"J Dairy Res"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0014","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0221-2022","article-title":"Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14 621 people","volume":"32","author":"Ivanova","year":"2023","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0015","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1103797","article-title":"Epigenetic liquid biopsies for minimal residual disease, what's around the corner?","volume":"13","author":"Johnston","year":"2023","journal-title":"Front Oncol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0016","article-title":"Xpert MTB\/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children","volume":"9","author":"Kay","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0017","doi-asserted-by":"crossref","first-page":"L412","DOI":"10.1152\/ajplung.00217.2021","article-title":"Latent tuberculosis testing through the ages: the search for a sleeping killer","volume":"322","author":"Kestler","year":"2022","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0018","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.756043","article-title":"Host-based biomarkers in Saliva for the diagnosis of pulmonary tuberculosis in children: a mini-review","volume":"9","author":"Khambati","year":"2021","journal-title":"Front Pediatr"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0019","doi-asserted-by":"crossref","first-page":"23351","DOI":"10.1038\/srep23351","article-title":"microRNA-146a promotes mycobacterial survival in macrophages through suppressing nitric oxide production","volume":"6","author":"Li","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0020","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/s41467-017-00972-z","article-title":"An NF-kappaB-microRNA regulatory network tunes macrophage inflammatory responses","volume":"8","author":"Mann","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0021","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/S0140-6736(21)00458-X","article-title":"Improving lung health in low-income and middle-income countries: from challenges to solutions","volume":"397","author":"Meghji","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0022","doi-asserted-by":"crossref","first-page":"e00649","DOI":"10.1128\/IAI.00649-19","article-title":"Unraveling the role of MicroRNAs in mycobacterium tuberculosis infection and disease: advances and pitfalls","volume":"88","author":"Ruiz-Tagle","year":"2020","journal-title":"Infect Immun"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0023","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.667206","article-title":"Monocyte and macrophage miRNA: potent biomarker and target for host-directed therapy for tuberculosis","volume":"12","author":"Sampath","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0024","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.3390\/cells9102160","article-title":"Tuberculosis-associated MicroRNAs: from pathogenesis to disease biomarkers","volume":"9","author":"Sinigaglia","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0025","first-page":"22","article-title":"miR-146 and miR-155: two key modulators of immune response and tumor development","volume":"3","author":"Testa","year":"2017","journal-title":"Noncoding RNA"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0026","first-page":"213","article-title":"Revised international definitions in tuberculosis control","volume":"5","author":"World Health","year":"2001","journal-title":"Int J Tuberc Lung Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0027","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.humimm.2011.10.003","article-title":"Analysis of microRNA expression profiling identifies miR-155 and miR-155* as potential diagnostic markers for active tuberculosis: a preliminary study","volume":"73","author":"Wu","year":"2012","journal-title":"Hum Immunol"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0028","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02625-21","article-title":"The Association between circulating microRNAs and the risk of active disease development from latent tuberculosis infection: a nested case-control study","volume":"10","author":"Xin","year":"2022","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0029","first-page":"1419","article-title":"MicroRNA-155 from sputum as noninvasive biomarker for diagnosis of active pulmonary tuberculosis","volume":"23","author":"Ying","year":"2020","journal-title":"Iran J Basic Med Sci"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0030","first-page":"170","article-title":"The diagnosis of latent tuberculosis infection (LTBI): currently available tests, future developments, and perspectives to eliminate tuberculosis (TB)","volume":"111","author":"Zellweger","year":"2020","journal-title":"Med Lav"},{"key":"10.1016\/j.diagmicrobio.2025.116795_bib0031","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/S1473-3099(20)30276-0","article-title":"Interferon-gamma release assays or tuberculin skin test for detection and management of latent tuberculosis infection: a systematic review and meta-analysis","volume":"20","author":"Zhou","year":"2020","journal-title":"Lancet Infect Dis"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288932500118X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288932500118X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T22:26:27Z","timestamp":1744237587000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073288932500118X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S073288932500118X"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2025.116795","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-invasive diagnosis of pulmonary tuberculosis and predictive potential for treatment outcomes via miR-146a and miR-155 levels","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2025.116795","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116795"}}