{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T19:40:09Z","timestamp":1768074009132,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2605103"],"award-info":[{"award-number":["2023YFC2605103"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2605100"],"award-info":[{"award-number":["2023YFC2605100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012175","name":"Zhejiang Administration Bureau of Traditional Chinese Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012175","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.diagmicrobio.2025.116843","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T07:21:10Z","timestamp":1744269670000},"page":"116843","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence, genomic features, and antibiotic sensitivities of Neisseria meningitidis isolates from patients with invasive meningococcal disease and healthy carriers in Zhejiang Province, 2015-2023"],"prefix":"10.1016","volume":"113","author":[{"given":"Lingbo","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuan","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4740-8807","authenticated-orcid":false,"given":"Zhangnv","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuoying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwu","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pingping","family":"Yao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanqing","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beibei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-61779-346-2_1","article-title":"Neisseria meningitidis: biology, microbiology, and epidemiology","volume":"799","author":"Rouphael","year":"2012","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4939-9202-7_1","article-title":"An overview of Neisseria meningitidis","volume":"1969","author":"Hollingshead","year":"2019","journal-title":"Methods Mol Biol"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0003","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.jinf.2015.07.007","article-title":"Genomic resolution of an aggressive, widespread, diverse and expanding meningococcal serogroup B, C and W lineage","volume":"71","author":"Lucidarme","year":"2015","journal-title":"J Infect"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0004","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1474-4422(18)30499-X","article-title":"Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","year":"2019","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0005","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1016\/j.vaccine.2017.03.007","article-title":"The epidemiology of invasive meningococcal disease in EU\/EEA countries, 2004-2014","volume":"35","author":"Whittaker","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0006","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.862935","article-title":"The host-pathogen interactions and epicellular lifestyle of Neisseria meningitidis","volume":"12","author":"Mikucki","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0007","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1084\/jem.129.6.1307","article-title":"Human immunity to the meningococcus. I. The role of humoral antibodies","volume":"129","author":"Goldschneider","year":"1969","journal-title":"J Exp Med"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0008","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.csbj.2018.02.002","article-title":"Interplay between virulence and variability factors as a potential driver of invasive meningococcal disease","volume":"16","author":"Siena","year":"2018","journal-title":"Comput Struct Biotechnol J"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0009","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s40121-020-00291-9","article-title":"Carriage of Neisseria Meningitidis in low and middle income countries of the Americas and Asia: a review of the literature","volume":"9","author":"Serra","year":"2020","journal-title":"Infect Dis Ther"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0010","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S1473-3099(10)70251-6","article-title":"Meningococcal carriage by age: a systematic review and meta-analysis","volume":"10","author":"Christensen","year":"2010","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0011","doi-asserted-by":"crossref","first-page":"e228","DOI":"10.1017\/S0950268819001134","article-title":"Meningococcal carriage by age in the African meningitis belt: a systematic review and meta-analysis","volume":"147","author":"Cooper","year":"2019","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0012","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1093\/infdis\/jiac095","article-title":"Evolution of resistance to antibiotics in Neisseria meningitidis: any reasons for concern?","volume":"225","author":"Taha","year":"2022","journal-title":"J Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0013","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1128\/AAC.49.2.536-540.2005","article-title":"Mutations in folP associated with elevated sulfonamide MICs for Neisseria meningitidis clinical isolates from five continents","volume":"49","author":"Fiebelkorn","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0014","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ijmmb.2022.05.005","article-title":"A systematic review and meta-analysis on the antibiotic resistance of Neisseria meningitidis in the last 20 years in the world","volume":"40","author":"Rostamian","year":"2022","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0015","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.3201\/eid2704.203612","article-title":"Evolution of sequence type 4821 clonal complex hyperinvasive and quinolone-resistant meningococci","volume":"27","author":"Chen","year":"2021","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.physrep.2021.02.001","article-title":"Non-pharmaceutical interventions during the COVID-19 pandemic: a review","volume":"913","author":"Perra","year":"2021","journal-title":"Phys Rep"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0017","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/s41562-021-01079-8","article-title":"A global panel database of pandemic policies (Oxford COVID-19 Government Response Tracker)","volume":"5","author":"Hale","year":"2021","journal-title":"Nat Hum Behav"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0018","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1038\/s41467-022-29534-8","article-title":"Modeling the disruption of respiratory disease clinical trials by non-pharmaceutical COVID-19 interventions","volume":"13","author":"Arsene","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0019","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1186\/s12879-022-07586-x","article-title":"Carriage prevalence of Neisseria meningitidis in China, 2005-2022: a systematic review and meta-analysis","volume":"22","author":"Yue","year":"2022","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0020","first-page":"123","article-title":"[Experts' consensus on immunization with meningococcal vaccines in China]","volume":"40","year":"2019","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0021","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1017\/S0950268811001865","article-title":"Distribution of serogroups and sequence types in disease-associated and carrier strains of Neisseria meningitidis isolated in China between 2003 and 2008","volume":"140","author":"Zhou","year":"2012","journal-title":"Epidemiol Infect"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2025.116843_bib0022","first-page":"001124","article-title":"Genetic variants linked to the phenotypic outcome of invasive disease and carriage of Neisseria meningitidis","volume":"9","author":"Eriksson","year":"2023","journal-title":"Microb Genom"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0023","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1080\/14787210.2017.1333422","article-title":"An unwanted guest: Neisseria meningitidis - carriage, risk for invasive disease and the impact of vaccination with insight on Italy incidence","volume":"15","author":"Gianchecchi","year":"2017","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.diagmicrobio.2025.116843_bib0024","article-title":"The epidemiology of Meningococcal disease and carriage, genotypic characteristics and antibiotic resistance of Neisseria meningitidis isolates in Zhejiang Province, China, 2011-2021","volume":"12","author":"Zhang","year":"2021","journal-title":"Front Microbiol"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288932500166X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073288932500166X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T22:03:50Z","timestamp":1750284230000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073288932500166X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S073288932500166X"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2025.116843","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence, genomic features, and antibiotic sensitivities of Neisseria meningitidis isolates from patients with invasive meningococcal disease and healthy carriers in Zhejiang Province, 2015-2023","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2025.116843","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116843"}}