{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T02:21:34Z","timestamp":1762309294402,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.diagmicrobio.2025.116873","type":"journal-article","created":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T11:50:24Z","timestamp":1746273024000},"page":"116873","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Value of a commercial multiplex molecular panel for the diagnosis of cholera in an outbreak setting in Hammanskraal, Tshwane, South Africa"],"prefix":"10.1016","volume":"113","author":[{"given":"Khan","family":"Safiyyah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5684-9930","authenticated-orcid":false,"given":"Lebogang Busisiwe","family":"Skosana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5048-8399","authenticated-orcid":false,"given":"Jamie","family":"Colloty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maphoshane","family":"Nchabeleng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace","family":"Ntlemo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2610-0440","authenticated-orcid":false,"given":"Mohamed","family":"Said","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0001","doi-asserted-by":"crossref","unstructured":"Kanungo S., Azman A.S., Ramamurthy T., Deen J., Dutta S. Cholera. The Lanc. 2022;399(10333):1429-40. https:\/\/doi.org\/10.1016\/S0140-6736(22)00330-0.","DOI":"10.1016\/S0140-6736(22)00330-0"},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0002","unstructured":"World Health Organization. Cholera, https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/cholera; 2024 [accessed 6 November 2024]."},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0003","unstructured":"World Health Organization. Weekly Epidemiological Record 2023, https:\/\/iris.who.int\/bitstream\/handle\/10665\/372986\/WER9838-eng-fre.pdf?sequence=1&isAllowed=y; 2023 [accessed 12 November 2024]."},{"issue":"6","key":"10.1016\/j.diagmicrobio.2025.116873_bib0004","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003832","article-title":"Updated global burden of cholera in endemic countries","volume":"9","author":"Ali","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"year":"2017","series-title":"Interim guidance document on cholera surveillance","key":"10.1016\/j.diagmicrobio.2025.116873_bib0005"},{"issue":"23","key":"10.1016\/j.diagmicrobio.2025.116873_bib0006","article-title":"Detection of common diarrhea-causing pathogens in Northern Taiwan by multiplex polymerase chain reaction","volume":"97","author":"Huang","year":"2018","journal-title":"Med"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2025.116873_bib0007","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0011113","article-title":"Development of a simple, rapid, and sensitive molecular diagnostic assay for cholera","volume":"17","author":"Chakraborty","year":"2023","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2025.116873_bib0008","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.cmi.2021.08.027","article-title":"Accuracy of cholera rapid diagnostic tests: a systematic review and meta-analysis","volume":"28","author":"Muzembo","year":"2022","journal-title":"Clin Microbiol Infect"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2025.116873_bib0009","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/tmi.13998","article-title":"Evaluation of a rapid diagnostic test for detection of Vibrio cholerae O1 in the Democratic Republic of the Congo: Preventative intervention for cholera for 7 days (PICHA7 program)","volume":"29","author":"George","year":"2024","journal-title":"Trop Med Int Health"},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0010","series-title":"Target product profile for a molecular test for surveillance of cholera","article-title":"Global Task Force on Cholera control","author":"Osborn","year":"2024"},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2021.116416","article-title":"A comprehensive review of conventional techniques and biosensor systems developed for in situ detection of Vibrio cholerae","volume":"144","author":"Yilmaz","year":"2021","journal-title":"Trend Anal Chem"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2025.116873_bib0012","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0168257","article-title":"Cholera rapid test with enrichment step has diagnostic performance equivalent to culture","volume":"11","author":"Ontweka","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2025.116873_bib0013","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1128\/JCM.02674-14","article-title":"Multicenter evaluation of the BioFire FilmArray gastrointestinal panel for etiologic diagnosis of infectious gastroenteritis","volume":"53","author":"Buss","year":"2015","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0014","series-title":"114th General Meeting-American Society of Microbiology","article-title":"Test performance of the FilmArray gastrointestinal panel (BioFire) from a clinical trial study in Hawaii","author":"Clinton","year":"2014"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2025.116873_bib0015","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s12866-017-1018-2","article-title":"FilmArrayTM GI panel performance for the diagnosis of acute gastroenteritis or hemorragic diarrhea","volume":"17","author":"Piralla","year":"2017","journal-title":"BMC Microbiol"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2025.116873_bib0016","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1099\/jmm.0.074773-0","article-title":"Evaluation of the Luminex xTAG gastrointestinal pathogen panel and the savyon diagnostics gastrointestinal infection panel for the detection of enteric pathogens in clinical samples","volume":"63","author":"Perry","year":"2014","journal-title":"J Med Microbiol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2025.116873_bib0017","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1128\/JCM.03321-15","article-title":"Evaluation of Luminex xTAG gastrointestinal pathogen panel assay for detection of multiple diarrheal pathogens in fecal samples in Vietnam","volume":"54","author":"Duong","year":"2016","journal-title":"J Clin Microbiol"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2025.116873_bib0018","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1159\/000447698","article-title":"Evaluation of the xTAG gastrointestinal pathogen panel assay for the detection of enteric pathogens in Kuwait","volume":"25","author":"Albert","year":"2016","journal-title":"Med Princ Pr"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2025.116873_bib0019","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01737-19","article-title":"Performance of the QIAstat-Dx gastrointestinal panel for diagnosing infectious gastroenteritis","volume":"58","author":"Boers","year":"2020","journal-title":"J Clin Microbiol"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2025.116873_bib0020","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00859-23","article-title":"QIAstat-Dx gastrointestinal panel and Luminex xTAG gastrointestinal pathogen panel comparative evaluation","volume":"61","author":"Giffen","year":"2023","journal-title":"J Clin Microbiol"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2025.116873_bib0021","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/jac\/dkab242","article-title":"Verification of analytical bacterial spectrum of QIAstat-Dx\u00ae GI V2 and Novodiag\u00ae Bacterial GE+ V2-0 diagnostic panels","volume":"76","author":"Engberg","year":"2021","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0022","series-title":"28th European Congress of Clinical Microbiology and Infectious diseases, Apr 21-24","article-title":"Evaluation of EntericBio Bacterial Panel 3 for direct detection of Salmonella, Shigella, Campylobacter, Shiga-like toxin-producing E. coli (STEC), Yersinia and Vibrio in stool samples","author":"Jonckheere","year":"2018"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2025.116873_bib0023","first-page":"574","article-title":"Evaluation of the Luminex xTAG\u00ae-GPP (Gastrointestinal Pathogen Panel) in the diagnosis of diseases with acute diarrhoea","volume":"35","author":"Casa\u00f1","year":"2017","journal-title":"Inf Dis ClinMicrobiol"},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0024","unstructured":"Serosep. EntericBio, https:\/\/www.serosep.com\/product\/entericbio-pcr-testing-realtime-enteric-pathogen-testing [accessed 10 October 2024]."},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0025","unstructured":"National Department of Health. Health Department provides update on Cholera outbreak in South Africa. https:\/\/www.health.gov.za\/wp-content\/uploads\/2023\/07\/Health-Department-provides-update-on-cholera-outbreak-in-SA-05-July-2023.pdf; 2023 [accessed 7 November 2024]."},{"key":"10.1016\/j.diagmicrobio.2025.116873_bib0026","doi-asserted-by":"crossref","unstructured":"Garcia L.S. Fecal and other gastrointestinal cultures and toxin assays. In: Clinical Microbiology Procedures Handbook. 3rd ed. Washington: ASM Press; 2016, p. 3.8.1.5-3.8.1.15.","DOI":"10.1128\/9781555818814.ch3.8.1"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2025.116873_bib0027","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/MOG.0000000000000405","article-title":"Molecular versus culture-based testing for gastrointestinal infection","volume":"34","author":"Macfarlane-Smith","year":"2018","journal-title":"Curr Opin Gastroenterol"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2025.116873_bib0028","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jinf.2014.11.009","article-title":"A cost benefit analysis of the Luminex xTAG Gastrointestinal Pathogen Panel for detection of infectious gastroenteritis in hospitalised patients","volume":"70","author":"Goldenberg","year":"2015","journal-title":"J Infect"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2025.116873_bib0029","doi-asserted-by":"crossref","first-page":"179.e9","DOI":"10.1016\/j.cmi.2014.07.011","article-title":"How well does physician selection of microbiologic tests identify Clostridium difficile and other pathogens in paediatric diarrhoea? Insights using multiplex PCR-based detection","volume":"21","author":"Stockmann","year":"2015","journal-title":"Clin Microbiol Infect"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2025.116873_bib0030","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1128\/JCM.01637-14","article-title":"Comparative Evaluation of Two Commercial Multiplex Panels for Detection of Gastrointestinal Pathogens by Use of Clinical Stool Specimens","volume":"52","author":"Khare","year":"2020","journal-title":"J Clin Microbiol"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889325001968?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889325001968?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T02:16:53Z","timestamp":1762309013000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889325001968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S0732889325001968"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2025.116873","relation":{},"ISSN":["0732-8893"],"issn-type":[{"type":"print","value":"0732-8893"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Value of a commercial multiplex molecular panel for the diagnosis of cholera in an outbreak setting in Hammanskraal, Tshwane, South Africa","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2025.116873","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116873"}}