{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:08:40Z","timestamp":1779376120374,"version":"3.53.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100015285","name":"Hebei Province Medical Science Research Key Project","doi-asserted-by":"publisher","award":["20231299"],"award-info":[{"award-number":["20231299"]}],"id":[{"id":"10.13039\/501100015285","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.diagmicrobio.2026.117326","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T07:44:37Z","timestamp":1771400677000},"page":"117326","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Automated urine yeast-like cell count for risk stratification in ICU patients: Diagnostic performance and clinical utility"],"prefix":"10.1016","volume":"115","author":[{"given":"Yuekun","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueqi","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sitong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanbing","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingqing","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinrui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8642-2866","authenticated-orcid":false,"given":"Zhengxin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0001","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/s13054-019-2497-3","article-title":"Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project","volume":"23","author":"Bassetti","year":"2019","journal-title":"Crit Care"},{"issue":"31","key":"10.1016\/j.diagmicrobio.2026.117326_bib0002","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000034469","article-title":"A prospective surveillance study of healthcare-associated infections in an intensive care unit from a tertiary care teaching hospital from 2012 to 2019","volume":"102","author":"Li","year":"2023","journal-title":"Medicine"},{"issue":"46","key":"10.1016\/j.diagmicrobio.2026.117326_bib0003","doi-asserted-by":"crossref","first-page":"1800516","DOI":"10.2807\/1560-7917.ES.2018.23.46.1800516","article-title":"Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017","volume":"23","author":"Suetens","year":"2018","journal-title":"Euro Surveill"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117326_bib0004","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3390\/jof11020152","article-title":"Candidemia in ICU patients: what are the real game-changers for survival?","volume":"11","author":"de Almeida","year":"2025","journal-title":"J Fungi"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117326_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.diagmicrobio.2024.116493","article-title":"A decade of candidaemia: a comprehensive analysis of prognosis and risk factors at a Belgian tertiary hospital","volume":"110","author":"Deckers","year":"2024","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117326_bib0006","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3390\/jof7020079","article-title":"Candida albicans-the virulence factors and clinical manifestations of infection","volume":"7","author":"Talapko","year":"2021","journal-title":"J Fungi"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117326_bib0007","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3390\/jof11050377","article-title":"Retrospective analysis of fungal isolations in patients on veno-venous extracorporeal membrane oxygenation: the multicenter RANGER STUDY 2.0","volume":"11","author":"Boscolo","year":"2025","journal-title":"J Fungi"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117326_bib0008","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1007\/s00134-003-1807-y","article-title":"Candiduria in critically ill patients admitted to intensive care medical units","volume":"29","author":"Alvarez-Lerma","year":"2003","journal-title":"Intensive Care Med"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0009","first-page":"156","article-title":"Candiduria in hospitalized patients and identification of isolated Candida species by morphological and molecular methods in Ilam, Iran","volume":"48","author":"Fazeli","year":"2019","journal-title":"Iran J Public Health"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0010","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1186\/s13054-025-05544-y","article-title":"Candida auris infections in ICU patients: risk factors, outcomes, and antifungal resistance patterns","volume":"29","author":"Choudhury","year":"2025","journal-title":"Crit Care"},{"issue":"Suppl 6","key":"10.1016\/j.diagmicrobio.2026.117326_bib0011","doi-asserted-by":"crossref","first-page":"S457","DOI":"10.1093\/cid\/cir112","article-title":"Candida urinary tract infections\u2013treatment","volume":"52","author":"Fisher","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117326_bib0012","doi-asserted-by":"crossref","first-page":"275","DOI":"10.3390\/jof7040275","article-title":"Epidemiological trends of candidemia and the impact of adherence to the candidemia guideline: six-year single-center experience","volume":"7","author":"Kim","year":"2021","journal-title":"J Fungi"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117326_bib0013","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.3390\/jcm8122098","article-title":"Clinical validation of innovative optical-sensor-based, low-cost, rapid diagnostic test to reduce antimicrobial resistance","volume":"8","author":"Kapur","year":"2019","journal-title":"J Clin Med"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0014","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.915288","article-title":"A novel approach to screening and managing the urinary tract infections suspected sample in the general human population","volume":"12","author":"Szmulik","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117326_bib0015","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s10096-019-03491-5","article-title":"Performance of yeast-like cell counting (YLCC) using the Sysmex UF-1000i for clinical candiduria screening","volume":"38","author":"Zhengxin","year":"2019","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117326_bib0016","first-page":"292","article-title":"Performance of Sysmex UF-5000 for candiduria screening","volume":"45","author":"Yan\u0131lmaz","year":"2022","journal-title":"New Microbiol"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0017","doi-asserted-by":"crossref","first-page":"e6935","DOI":"10.7717\/peerj.6935","article-title":"Candiduria in hospitalized patients: an investigation with the Sysmex UF-1000i urine analyzer","volume":"7","author":"He","year":"2019","journal-title":"PeerJ"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0018","article-title":"Whole blood ratio of CDK1\/CX3CR1 mRNA expression combined to lactate refines the prediction of ICU mortality in septic patients in the Sepsis-3 era: a proof-of-concept study","volume":"11","author":"Cazalis","year":"2024","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.cca.2025.120212","article-title":"The value of midregional proadrenomedullin to predict mortality in intensive care unit","volume":"570","author":"Agnello","year":"2025","journal-title":"Clin Chim Acta"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0020","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-09391-3","article-title":"A case-control study on the diagnostic role of omega-3 fatty acid levels in erythrocyte membranes of critically ill patients","volume":"15","author":"Dorchin","year":"2025","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0021","doi-asserted-by":"crossref","first-page":"23","DOI":"10.6061\/clinics\/2017(01)05","article-title":"Predictive value of C-reactive protein in critically ill patients after abdominal surgery","volume":"72","author":"Sapin","year":"2017","journal-title":"Clinics (Sao Paulo)"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0022","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.diagmicrobio.2012.08.026","article-title":"IRIS iQ200 workstation as a screen for performing urine culture","volume":"75","author":"Parta","year":"2013","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2026.117326_bib0023","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s00134-014-3355-z","article-title":"Candida colonization index and subsequent infection in critically ill surgical patients: 20 years later","volume":"40","author":"Eggimann","year":"2014","journal-title":"Intensive Care Med"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0024","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/2110-5820-1-50","article-title":"Evaluation of \"Candida score\" in critically ill patients: a prospective, multicenter, observational, cohort study","volume":"1","author":"Leroy","year":"2011","journal-title":"Ann Intensive Care"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117326_bib0025","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/civ933","article-title":"Clinical practice guideline for the management of candidiasis: 2016 update by the infectious diseases society of America","volume":"62","author":"Pappas","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117326_bib0026","doi-asserted-by":"crossref","first-page":"P19","DOI":"10.1186\/cc11706","article-title":"Candiduria in ICUs: incidence, course and outcome","volume":"16","author":"Juneja","year":"2012","journal-title":"Critical Care"},{"issue":"Suppl 2","key":"10.1016\/j.diagmicrobio.2026.117326_bib0027","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1016\/S0924-8579(08)70006-2","article-title":"Epidemiology of candidemia in intensive care units","volume":"32","author":"Bouza","year":"2008","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0028","doi-asserted-by":"crossref","first-page":"489","DOI":"10.2147\/IDR.S289885","article-title":"Evaluation of a novel laboratory candiduria screening protocol in the Intensive Care unit","volume":"14","author":"He","year":"2021","journal-title":"Infect Drug Resist"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117326_bib0029","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.3390\/antibiotics11121804","article-title":"How to identify invasive candidemia in ICU-A narrative review","volume":"11","author":"Alves","year":"2022","journal-title":"Antibiotics (Basel)"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117326_bib0030","doi-asserted-by":"crossref","first-page":"e01487","DOI":"10.1128\/JCM.01487-19","article-title":"Updates in laboratory diagnostics for invasive fungal infections","volume":"58","author":"Terrero-Salcedo","year":"2020","journal-title":"J Clin Microbiol"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117326_bib0031","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1164\/rccm.201906-1185ST","article-title":"Microbiological laboratory testing in the diagnosis of fungal infections in pulmonary and critical care practice. An official American Thoracic Society Clinical Practice guideline","volume":"200","author":"Hage","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117326_bib0032","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/s00134-007-0865-y","article-title":"Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome","volume":"34","author":"Bougnoux","year":"2008","journal-title":"Intensive Care Med"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117326_bib0033","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0146071","article-title":"Flow cytometry approach to quantify the viability of milk somatic cell counts after various physico-chemical treatments","volume":"10","author":"Li","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117326_bib0034","doi-asserted-by":"crossref","DOI":"10.1016\/j.resmic.2021.103915","article-title":"Fungal infections diagnosis - past, present and future","volume":"173","author":"Mendon\u00e7a","year":"2022","journal-title":"Res Microbiol"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0035","article-title":"Candida albicans fungaemia following traumatic urethral catheterisation in a paraplegic patient with diabetes mellitus and candiduria treated by Caspofungin","volume":"2013","author":"Vaidyanathan","year":"2013","journal-title":"Case Rep Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2026.117326_bib0036","article-title":"Prokinetic effect of erythromycin in the management of gastroparesis in critically ill patients-our experience and literature review","volume":"11","author":"Szczupak","year":"2024","journal-title":"Front Med (Lausanne)"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117326_bib0037","first-page":"11","article-title":"Invasive fungal infections among critically ill children: epidemiology, risk factors and outcomes","volume":"24","author":"Hlophe","year":"2018","journal-title":"Afr J Thorac Crit Care Med"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117326_bib0038","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.riam.2012.03.002","article-title":"Towards an early diagnosis of invasive candidiasis in the critically ill patient]","volume":"29","author":"Pem\u00e1n","year":"2012","journal-title":"Rev Iberoam Micol"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326000763?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326000763?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T14:37:51Z","timestamp":1779374271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326000763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0732889326000763"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117326","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Automated urine yeast-like cell count for risk stratification in ICU patients: Diagnostic performance and clinical utility","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117326","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117326"}}