{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:20:52Z","timestamp":1792855252373,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:00:00Z","timestamp":1772496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.diagmicrobio.2026.117353","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T17:20:12Z","timestamp":1772558412000},"page":"117353","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic value of paediatric blood culture bottle allied to MALDI-TOF mass spectrometry in the aetiological assessment of microbial keratitis"],"prefix":"10.1016","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1815-4644","authenticated-orcid":false,"given":"Juliana Mika","family":"Kato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiza Manhezi","family":"Shin de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana","family":"Santana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelina da Motta Pacheco Alves","family":"de Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce Hisae","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth Miyuki","family":"Santo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117353_bib0001","doi-asserted-by":"crossref","first-page":"e1221","DOI":"10.1016\/S2214-109X(17)30393-5","article-title":"Global causes of blindness and distance vision impairment 1990-2020: a systematic review and meta-analysis","volume":"5","author":"Flaxman","year":"2017","journal-title":"Lancet Glob Health"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0002","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.jtos.2021.08.007","article-title":"The epidemiology of infectious keratitis","volume":"28","author":"Stapleton","year":"2023","journal-title":"Ocul Surf"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0003","volume":"2","author":"Jones","year":"1981"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117353_bib0004","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00070-19","article-title":"Practical guidance for clinical microbiology laboratories: diagnosis of ocular infections","volume":"34","author":"Leal","year":"2021","journal-title":"Clin Microbiol Rev"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117353_bib0005","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1128\/JCM.02919-15","article-title":"Diagnosis of bloodstream infections in children","volume":"54","author":"Dien Bard","year":"2016","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117353_bib0006","doi-asserted-by":"crossref","first-page":"P1","DOI":"10.1016\/j.ophtha.2018.10.018","article-title":"American Academy of Ophthalmology preferred practice pattern cornea and external disease panel. Bacterial keratitis preferred practice pattern\u00ae","volume":"126","author":"Lin","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0007","series-title":"Manual de coletas em oftalmologia","article-title":"\u00dalceras de c\u00f3rnea","author":"Shin de Oliveira","year":"2019"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0008","unstructured":"CLSI, Clinical laboratory standard institute. Performance standards for antimicrobial susceptibility testing; twenty-six informational supplement. Document M100-ED19 Wayne, PA, 2019."},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117353_bib0009","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1167\/iovs.61.2.18","article-title":"The microbiome of the meibum and ocular surface in healthy subjects","volume":"61","author":"Suzuki","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117353_bib0010","article-title":"Does the sampling instrument influence corneal culture outcome in patients with infectious keratitis? A retrospective study comparing cotton tipped applicator with knife blade","volume":"5","author":"Sagerfors","year":"2020","journal-title":"BMJ Open Ophthalmol"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117353_bib0011","doi-asserted-by":"crossref","first-page":"854","DOI":"10.2471\/BLT.19.232660","article-title":"Infectious corneal ulceration: a proposal for neglected tropical disease status","volume":"97","author":"Ung","year":"2019","journal-title":"Bull World Health Organ"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117353_bib0012","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/bjophthalmol-2020-316128","article-title":"12-year analysis of incidence, microbiological profiles and in vitro antimicrobial susceptibility of infectious keratitis: the Nottingham Infectious Keratitis Study","volume":"105","author":"Ting","year":"2021","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0013","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ajo.2018.09.032","article-title":"Laboratory results, epidemiologic features, and outcome analyses of microbial keratitis: a 15-year review from St. Louis","volume":"198","author":"Hsu","year":"2019","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117353_bib0014","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1136\/bjophthalmol-2014-305000","article-title":"Trends in bacterial and fungal keratitis in South India, 2002-2012","volume":"99","author":"Lalitha","year":"2015","journal-title":"Br J Ophthalmol"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117353_bib0015","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1097\/ICO.0000000000003105","article-title":"Trends in the microbiological spectrum of nonviral keratitis at a single tertiary care ophthalmic hospital in India: a review of 30 years","volume":"42","author":"Joseph","year":"2023","journal-title":"Cornea"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0016","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.2147\/IDR.S206831","article-title":"Nine-year analysis of isolated pathogens and antibiotic susceptibilities of microbial keratitis from a large referral eye center in southern China","volume":"12","author":"Lin","year":"2019","journal-title":"Infect Drug Resist"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117353_bib0017","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1128\/CMR.00072-12","article-title":"Matrix-assisted laser desorption ionization-time of flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology","volume":"26","author":"Clark","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0018","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jtos.2021.11.003","article-title":"Diagnostic armamentarium of infectious keratitis: a comprehensive review","volume":"23","author":"Ting","year":"2022","journal-title":"Ocul Surf"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0019","doi-asserted-by":"crossref","DOI":"10.6061\/clinics\/2019\/e837","article-title":"Diagnostic value of pediatric blood culture bottles for acute postoperative endophthalmitis","volume":"74","author":"Tanaka","year":"2019","journal-title":"Clin (Sao Paulo)"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117353_bib0020","doi-asserted-by":"crossref","first-page":"4468","DOI":"10.1128\/JCM.39.12.4468-4471.2001","article-title":"Culture with BACTEC Peds Plus\/F bottle compared with conventional methods for detection of bacteria in synovial fluid","volume":"39","author":"Hughes","year":"2001","journal-title":"J Clin Microbiol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117353_bib0021","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.diagmicrobio.2015.12.016","article-title":"Higher recovery rate of microorganisms from cerebrospinal fluid samples by the BACTEC culture system in comparison with agar culture","volume":"84","author":"Calderaro","year":"2016","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117353_bib0022","doi-asserted-by":"crossref","first-page":"5408","DOI":"10.1167\/iovs.10-6939","article-title":"Diversity of bacteria at healthy human conjunctiva","volume":"52","author":"Dong","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"13","key":"10.1016\/j.diagmicrobio.2026.117353_bib0023","doi-asserted-by":"crossref","first-page":"5116","DOI":"10.1167\/iovs.16-19803","article-title":"Paucibacterial microbiome and resident DNA virome of the healthy conjunctiva","volume":"57","author":"Doan","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.diagmicrobio.2026.117353_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2023.109615","article-title":"Ocular microbiome changes in dry eye disease and meibomian gland dysfunction","volume":"235","author":"Ozkan","year":"2023","journal-title":"Exp Eye Res"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117353_bib0025","doi-asserted-by":"crossref","first-page":"9880","DOI":"10.1038\/s41598-017-10494-9","article-title":"Temporal stability and composition of the ocular surface microbiome","volume":"7","author":"Ozkan","year":"2017","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117353_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajo.2014.09.021","article-title":"The corneal ulcer one-touch study: a simplified microbiological specimen collection method","volume":"159","author":"Pakzad-Vaezi","year":"2015","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117353_bib0027","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.ajo.2005.06.042","article-title":"Reliability of transport medium in the laboratory evaluation of corneal ulcers","volume":"140","author":"McLeod","year":"2005","journal-title":"Am J Ophthalmol"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2026.117353_bib0028","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.3390\/jcm10091810","article-title":"Corneal culture in infectious keratitis: effect of the inoculation method and media on the Corneal culture outcome","volume":"10","author":"Sagerfors","year":"2021","journal-title":"J Clin Med"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117353_bib0029","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.jfo.2019.10.010","article-title":"Comparison of two methods for obtaining and transporting corneal samples in suspected infectious keratitis","volume":"43","author":"Chang-Sotomayor","year":"2020","journal-title":"J Fr Ophtalmol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117353_bib0030","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/sj.eye.6701858","article-title":"Broth cultures yield vs traditional approach in the workup of infectious keratitis","volume":"20","author":"Kratz","year":"2006","journal-title":"Eye (L)"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326001033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326001033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T02:28:13Z","timestamp":1775528893000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326001033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0732889326001033"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117353","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic value of paediatric blood culture bottle allied to MALDI-TOF mass spectrometry in the aetiological assessment of microbial keratitis","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117353","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117353"}}