{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T18:55:38Z","timestamp":1787684138457,"version":"build-2784847793"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.diagmicrobio.2026.117387","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T16:42:16Z","timestamp":1773852136000},"page":"117387","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["A gated pathway for suspected urinary tract infection in dementia"],"prefix":"10.1016","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2818-7474","authenticated-orcid":false,"given":"Rob E.","family":"Carpenter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Krouse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117387_bib0001","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1042\/BST0390945","article-title":"Systemic inflammation and delirium: important co-factors in the progression of dementia","volume":"39","author":"Cunningham","year":"2011","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0002","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1749-6632.2000.tb06651.x","article-title":"Inflamm-aging: an evolutionary perspective on immunosenescence","volume":"908","author":"Franceschi","year":"2000","journal-title":"Ann N Y Acad Sci"},{"issue":"20","key":"10.1016\/j.diagmicrobio.2026.117387_bib0003","first-page":"22403","article-title":"Immunology of aging: the birth of inflammaging","volume":"13","author":"F\u00fcl\u00f6p","year":"2021","journal-title":"Aging"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117387_bib0004","doi-asserted-by":"crossref","first-page":"519","DOI":"10.2217\/ahe.13.38","article-title":"Urinary tract infection in older adults","volume":"9","author":"Rowe","year":"2013","journal-title":"Aging Health"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2026.117387_bib0005","doi-asserted-by":"crossref","first-page":"e83","DOI":"10.1093\/cid\/ciy1121","article-title":"Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the infectious diseases society of America","volume":"68","author":"Nicolle","year":"2019","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117387_bib0006","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/jgs.12070","article-title":"Challenges in assessing nursing home residents with advanced dementia for suspected urinary tract infections","volume":"61","author":"EMC","year":"2013","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0007","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1007\/s00415-003-1029-9","article-title":"Autonomic dysfunctions in dementia with Lewy bodies","volume":"250","author":"Horimoto","year":"2003","journal-title":"J Neurol"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117387_bib0008","doi-asserted-by":"crossref","first-page":"121","DOI":"10.7326\/0003-4819-143-2-200507190-00011","article-title":"Patient safety concerns arising from test results that return after hospital discharge","volume":"143","author":"Roy","year":"2005","journal-title":"Ann Intern Med"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117387_bib0009","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s11606-010-1583-7","article-title":"Pending laboratory tests and the hospital discharge summary in patients discharged to sub-acute care","volume":"26","author":"Walz","year":"2011","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0010","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12877-019-1049-7","article-title":"The scientific evidence for a potential link between confusion and urinary tract infection in the elderly is still confusing: a systematic literature review","volume":"19","author":"Mayne","year":"2019","journal-title":"BMC Geriatr"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117387_bib0011","doi-asserted-by":"crossref","first-page":"ofaa537","DOI":"10.1093\/ofid\/ofaa537","article-title":"Assessment of testing and treatment of asymptomatic bacteriuria initiated in the emergency department","volume":"7","author":"Petty","year":"2020","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmicom.2025.105079","article-title":"Approach to Clostridioides difficile diarrheal infection","volume":"2","author":"Louren\u00e7o","year":"2025","journal-title":"CMI Commun"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117387_bib0013","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1164\/rccm.201609-1848OC","article-title":"The timing of early antibiotics and hospital mortality in sepsis","volume":"196","author":"Liu","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2026.117387_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.jamda.2025.105746","article-title":"A need for a time-out: a consensus statement from the post-acute and long-term care medical association (PALTmed) on the use of urine polymerase chain reaction testing for urinary tract infections","volume":"26","author":"Zering","year":"2025","journal-title":"J Am Med Dir Assoc"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0015","article-title":"Clinical practice guideline by infectious diseases society of America (IDSA): 2025 guideline on management and treatment of complicated urinary tract infections: selection of antibiotic therapy for complicated UTI","author":"Trautner","year":"2025","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117387_bib0016","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1086\/501875","article-title":"Development of minimum criteria for the initiation of antibiotics in residents of long-term-care facilities: results of a consensus conference","volume":"22","author":"Loeb","year":"2001","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0017","unstructured":"Bilsen M.P. Beyond the cloudiness in urinary tract infection: definitions, diagnostics, and strategies for prevention [PhD Thesis]. Leiden University; 2024. Available from: https:\/\/hdl.handle.net\/1887\/4039634."},{"issue":"11","key":"10.1016\/j.diagmicrobio.2026.117387_bib0018","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2024.46711","article-title":"The proliferation of multiplex molecular testing for urinary tract infections","volume":"7","author":"Fitzpatrick","year":"2024","journal-title":"JAMA Netw Open"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2026.117387_bib0019","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1007\/s00134-021-06506-y","article-title":"Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021","volume":"47","author":"Evans","year":"2021","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0020","doi-asserted-by":"crossref","DOI":"10.1093\/cid\/ciae104","article-title":"Guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2024 update by the infectious diseases society of America (IDSA) and the American Society for Microbiology (ASM)","author":"Miller","year":"2024","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117387_bib0021","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.diagmicrobio.2016.03.005","article-title":"Distinguishing asymptomatic bacteriuria from urinary tract infection in the elderly\u2014the use of urine levels of heparin-binding protein and interleukin-6","volume":"85","author":"Kj\u00f6lvmark","year":"2016","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117387_bib0022","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/iju.13002","article-title":"Predictive value of urinary interleukin-6 for symptomatic urinary tract infections in a nursing home population","volume":"23","author":"Sund\u00e9n","year":"2016","journal-title":"Int J Urol"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117387_bib0023","doi-asserted-by":"crossref","first-page":"80","DOI":"10.36346\/sarjm.2024.v05i03.003","article-title":"Beyond standard urine culture: advanced molecular testing for urinary tract infections","volume":"5","author":"Carpenter","year":"2024","journal-title":"SAR J Med"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117387_bib0024","doi-asserted-by":"crossref","first-page":"107","DOI":"10.36346\/sarjpm.2024.v05i03.010","article-title":"Advancing clinical microbiology: applications and future of next-generation sequencing","volume":"5","author":"Carpenter","year":"2024","journal-title":"SAR J Pathol Microbiol"},{"key":"10.1016\/j.diagmicrobio.2026.117387_bib0025","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1221289","article-title":"Advantage of precision metagenomics for urinary tract infection diagnostics","volume":"13","author":"Almas","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117387_bib0026","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jamda.2020.04.019","article-title":"Anticholinergic drug burden and delirium: a systematic review","volume":"22","author":"Egberts","year":"2021","journal-title":"J Am Med Dir Assoc"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117387_bib0027","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1001\/archinte.165.7.808","article-title":"A prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs used to manage urinary incontinence","volume":"165","author":"Gill","year":"2005","journal-title":"Arch Intern Med"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326001379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326001379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T02:27:24Z","timestamp":1775528844000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326001379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0732889326001379"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117387","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A gated pathway for suspected urinary tract infection in dementia","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117387","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117387"}}