{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:53:22Z","timestamp":1791244402998,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.diagmicrobio.2026.117477","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T16:16:09Z","timestamp":1779466569000},"page":"117477","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Real-life performance of a galactomannoprotein-detecting lateral flow immunoassay (AspLFD) in lower respiratory tract and serum specimens for screening pulmonary aspergillosis"],"prefix":"10.1016","volume":"116","author":[{"given":"Andrea","family":"Medina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda \u00c1ngeles","family":"Clari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Tormo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Luis","family":"Pi\u00f1ana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Briones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Franco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Signes-Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nieves","family":"Carbonell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Solano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliseo","family":"Albert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3010-4110","authenticated-orcid":false,"given":"David","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117477_bib0001","doi-asserted-by":"crossref","first-page":"e428","DOI":"10.1016\/S1473-3099(23)00692-8","article-title":"Global incidence and mortality of severe fungal disease","volume":"24","author":"Denning","year":"2024","journal-title":"Lancet Infect Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117477_bib0002","doi-asserted-by":"crossref","DOI":"10.1093\/mmy\/myab064","article-title":"Emerging risk groups in critically ill patients","volume":"60","author":"Kluge","year":"2021","journal-title":"Med Mycol"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2026.117477_bib0003","doi-asserted-by":"crossref","first-page":"617","DOI":"10.3390\/jof11090617","article-title":"Pulmonary aspergillosis in immunocompromised critically ill patients: prevalence, risk factors, clinical features and diagnosis-A narrative review","volume":"11","author":"Bocci","year":"2025","journal-title":"J Fungi (Basel)"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117477_bib0004","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jinf.2018.02.012","article-title":"The burden of invasive aspergillosis in patients with haematological malignancy: a meta-analysis and systematic review","volume":"76","author":"van de Peppel","year":"2018","journal-title":"J Infect"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117477_bib0005","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/ajt.16248","article-title":"Risk factors for the development of invasive aspergillosis after kidney transplantation: systematic review and meta-analysis","volume":"21","author":"P\u00e9rez-Jacoiste As\u00edn","year":"2021","journal-title":"Am J Transplant"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117477_bib0006","doi-asserted-by":"crossref","first-page":"829","DOI":"10.3390\/jof10120829","article-title":"Current analytical methods and challenges for the clinical diagnosis of invasive pulmonary aspergillosis infection","volume":"10","author":"Schwarz","year":"2024","journal-title":"J Fungi"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117477_bib0007","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.medcli.2024.01.045","article-title":"Invasive aspergillosis: a comprehensive review","volume":"163","author":"Machado","year":"2024","journal-title":"Med Clin (Barc)"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117477_bib0008","doi-asserted-by":"crossref","first-page":"021","DOI":"10.1055\/s-0043-1776777","article-title":"Microbiological diagnosis of pulmonary aspergillus infections","volume":"45","author":"Aerts","year":"2024","journal-title":"Semin Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117477_bib0009","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1186\/s12879-025-10769-x","article-title":"Lateral-flow device for the diagnosis of invasive aspergillosis: a systematic review and diagnostic meta-analysis","volume":"25","author":"Fan","year":"2025","journal-title":"BMC Infect Dis"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117477_bib0010","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s11046-023-00739-9","article-title":"Implementation of lateral flow assays for the diagnosis of invasive aspergillosis in European hospitals: a survey from Belgium and a literature review of test performances in different patient populations","volume":"188","author":"Aerts","year":"2023","journal-title":"Mycopathologia"},{"key":"10.1016\/j.diagmicrobio.2026.117477_bib0011","unstructured":"Mercier T., Verweij P., Lehrnbecher T., White L., Alanio A., Lamoth F., et al. Update on fungal diagnostics ECIL-9. Paper presented at: 9th european conference on infections in leukaemia resources; September 15-17, 2022; Nice, France. Accessed October 20, 2025. https:\/\/ecil-leukaemia.com\/en\/resources\/resources-ecil."},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117477_bib0012","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1128\/CVI.00068-08","article-title":"Development of an immunochromatographic lateral-flow device for rapid serodiagnosis of invasive aspergillosis","volume":"15","author":"Thornton","year":"2008","journal-title":"Clin Vaccine Immunol"},{"issue":"61","key":"10.1016\/j.diagmicrobio.2026.117477_bib0013","first-page":"3721","article-title":"Detection of invasive pulmonary aspergillosis in haematological malignancy patients by using lateral-flow technology","author":"Thornton","year":"2012","journal-title":"J Vis Exp"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117477_bib0014","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/myc.12343","article-title":"Diagnostic accuracy of the aspergillus-specific bronchoalveolar lavage lateral-flow assay in haematological malignancy patients","volume":"58","author":"Prattes","year":"2015","journal-title":"Mycoses"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117477_bib0015","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s13054-015-0905-x","article-title":"Multicenter evaluation of a lateral-flow device test for diagnosing invasive pulmonary aspergillosis in ICU patients","volume":"19","author":"Eigl","year":"2015","journal-title":"Crit Care"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117477_bib0016","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1111\/myc.13176","article-title":"Evaluation of two lateral flow assays in BAL fluids for the detection of invasive pulmonary aspergillosis: a retrospective two-centre study","volume":"63","author":"Scharmann","year":"2020","journal-title":"Mycoses"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2026.117477_bib0017","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00948-22","article-title":"Performance of the JF5-based galactomannoprotein EIA compared to the lateral flow device and the galactomannan EIA in serum and bronchoalveolar lavage fluid","volume":"60","author":"Aerts","year":"2022","journal-title":"J Clin Microbiol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117477_bib0018","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1093\/mmy\/myz079","article-title":"Lateral flow assays for diagnosing invasive pulmonary aspergillosis in adult hematology patients: a comparative multicenter study","volume":"58","author":"Mercier","year":"2020","journal-title":"Med Mycol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117477_bib0019","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/s12941-023-00626-7","article-title":"Microbiological diagnosis of pulmonary invasive aspergillosis in critically ill patients with severe SARS-CoV-2 pneumonia: a bronchoalveolar study","volume":"22","author":"Estella","year":"2023","journal-title":"Ann Clin Microbiol Antimicrob"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117477_bib0020","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1007\/s10096-024-04830-x","article-title":"Evaluation of the JF5-based aspergillus galactomannoprotein lateral flow device for diagnosing invasive aspergillosis in cancer patients","volume":"43","author":"Wan","year":"2024","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117477_bib0021","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00950-24","article-title":"Serum antigen tests for the diagnosis of invasive aspergillosis: a retrospective comparison of five aspergillus antigen assays and one beta-D-glucan assay","volume":"62","author":"Schub","year":"2024","journal-title":"J Clin Microbiol"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2026.117477_bib0022","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1093\/cid\/ciaa295","article-title":"Prospective evaluation of the turbidimetric \u03b2-D-glucan assay and 2 lateral flow assays on serum in invasive aspergillosis","volume":"72","author":"Mercier","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117477_bib0023","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jinf.2018.05.001","article-title":"Diagnosis of invasive aspergillosis in hematological malignancy patients: performance of cytokines, asp LFD, and aspergillus PCR in same day blood and bronchoalveolar lavage samples","volume":"77","author":"Heldt","year":"2018","journal-title":"J Infect"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117477_bib0024","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1111\/myc.12327","article-title":"Performance of lateral flow device and galactomannan for the detection of aspergillus species in bronchoalveolar fluid of patients at risk for invasive pulmonary aspergillosis","volume":"58","author":"Miceli","year":"2015","journal-title":"Mycoses"},{"issue":"Suppl 2","key":"10.1016\/j.diagmicrobio.2026.117477_bib0025","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1093\/cid\/ciaa1751","article-title":"EORTC\/MSGERC definitions of invasive fungal diseases: summary of activities of the intensive care unit working group","volume":"72","author":"Bassetti","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117477_bib0026","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1007\/s00134-024-07341-7","article-title":"Invasive fungal diseases in adult patients in intensive care unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM","volume":"50","author":"Bassetti","year":"2024","journal-title":"Intensive Care Med"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117477_bib0027","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.03910-23","article-title":"Comparative performance of the platelia aspergillus antigen and aspergillus galactomannan antigen virclia monotest immunoassays in serum and lower respiratory tract specimens: a \"real-life\" experience","volume":"12","author":"Albert","year":"2024","journal-title":"Microbiol Spectr"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117477_bib0028","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02626-21","article-title":"Comparison of the performance of two galactomannan detection tests: platelia aspergillus ag and aspergillus galactomannan ag virclia monotest","volume":"10","author":"Calero","year":"2022","journal-title":"Microbiol Spectr"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117477_bib0029","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00044-23","article-title":"Retrospective multicenter evaluation of the VirClia galactomannan antigen assay for the diagnosis of pulmonary aspergillosis with bronchoalveolar lavage fluid samples from patients with hematological disease","volume":"61","author":"Buil","year":"2023","journal-title":"J Clin Microbiol"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117477_bib0030","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/cid\/ciz1008","article-title":"Revision and update of the consensus definitions of invasive fungal disease from the european organization for research and treatment of cancer and the mycoses study group education and research consortium","volume":"71","author":"Donnelly","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117477_bib0031","doi-asserted-by":"crossref","first-page":"e149","DOI":"10.1016\/S1473-3099(20)30847-1","article-title":"Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM\/ISHAM consensus criteria for research and clinical guidance","volume":"21","author":"Koehler","year":"2021","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117477_bib0032","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1007\/s00134-020-06091-6","article-title":"Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion","volume":"46","author":"Verweij","year":"2020","journal-title":"Intensive Care Med;"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117477_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinf.2024.106159","article-title":"Performance of the galactomannan test for the diagnosis of invasive pulmonary aspergillosis using non-invasive proximal airway samples","volume":"88","author":"Chun","year":"2024","journal-title":"J Infect"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117477_bib0034","doi-asserted-by":"crossref","DOI":"10.1111\/myc.70029","article-title":"Comparison of the equivalence of aspergillus antigen and PCR results between non-directed bronchial lavage and bronchoalveolar lavage-A prospective exploratory pilot study in critically ill patients","volume":"68","author":"Schroeder","year":"2025","journal-title":"Mycoses"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117477_bib0035","doi-asserted-by":"crossref","DOI":"10.1111\/myc.13789","article-title":"Performance of the IMMY\u00ae sona aspergillus lateral flow assay for the detection of galactomannan in tracheal aspirate samples from Brazilian patients with COVID-19-associated pulmonary aspergillosis: cross-sectional and systematic review of literature","volume":"67","author":"Dos Santos","year":"2024","journal-title":"Mycoses"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326002270?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326002270?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:08:09Z","timestamp":1791241689000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326002270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S0732889326002270"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117477","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Real-life performance of a galactomannoprotein-detecting lateral flow immunoassay (AspLFD) in lower respiratory tract and serum specimens for screening pulmonary aspergillosis","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117477","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117477"}}