{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:49:55Z","timestamp":1792068595932,"version":"4.4.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.diagmicrobio.2026.117578","type":"journal-article","created":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T17:26:55Z","timestamp":1785086815000},"page":"117578","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of the NMIC-150 system in identifying extended-spectrum beta-lactamases in clinical isolates"],"prefix":"10.1016","volume":"116","author":[{"given":"Yana","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117578_bib0001","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1128\/AAC.01452-08","article-title":"In vitro activity of ceftaroline alone and in combination against clinical isolates of resistant gram-negative pathogens, including beta-lactamase-producing Enterobacteriaceae and Pseudomonas aeruginosa","volume":"53","author":"Vidaillac","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0002","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1086\/498519","article-title":"Clinical and molecular epidemiology of extended-spectrum beta-lactamase-producing Escherichia coli as a cause of nosocomial infection or colonization: implications for control","volume":"42","author":"Rodr\u00edguez-Ba\u00f1o","year":"2006","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0003","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jhin.2015.10.001","article-title":"Impact of infection with extended-spectrum \u03b2-lactamase-producing Escherichia coli or Klebsiella species on outcome and hospitalization costs","volume":"92","author":"Maslikowska","year":"2016","journal-title":"J Hosp Infect"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0004","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1186\/s12864-024-10139-y","article-title":"Exploring the resistome, virulome, and mobilome of multidrug-resistant Klebsiella pneumoniae isolates: deciphering the molecular basis of carbapenem resistance","volume":"25","author":"Rahmat Ullah","year":"2024","journal-title":"BMC Genomics"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117578_bib0005","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1093\/cid\/cix893","article-title":"Carbapenemase-producing organisms: a global scourge","volume":"66","author":"Bonomo","year":"2018","journal-title":"Clin Infect Dis"},{"issue":"Suppl_4","key":"10.1016\/j.diagmicrobio.2026.117578_bib0006","doi-asserted-by":"crossref","first-page":"S316","DOI":"10.1093\/cid\/ciab776","article-title":"Genome sequencing identifies previously unrecognized Klebsiella pneumoniae outbreaks in neonatal intensive care units in the Philippines","volume":"73","author":"Carlos","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0007","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1186\/s12864-025-11509-w","article-title":"Comprehensive genomic epidemiology and antimicrobial resistance profiles of clinical Klebsiella pneumoniae species complex isolates from a tertiary hospital in Wenzhou, China (2019-2021)","volume":"26","author":"Jiang","year":"2025","journal-title":"BMC Genomics"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0008","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.3390\/antibiotics12111591","article-title":"Antimicrobial activities of Aztreonam-avibactam and comparator agents against enterobacterales analyzed by ICU and non-ICU wards, infection sources, and geographic regions: ATLAS program 2016-2020","volume":"12","author":"Pi\u00e9rard","year":"2023","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0009","series-title":"Verification of commercial microbial identification and antimicrobial susceptibility testing systems","year":"2015"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117578_bib0010","doi-asserted-by":"crossref","first-page":"333","DOI":"10.3201\/eid0702.010238","article-title":"Controversies about extended-spectrum and AmpC beta-lactamases","volume":"7","author":"Thomson","year":"2001","journal-title":"Emerg Infect Dis"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117578_bib0011","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S1473-3099(19)30755-8","article-title":"Molecular and clinical epidemiology of carbapenem-resistant enterobacterales in the USA (CRACKLE-2): a prospective cohort study","volume":"20","author":"van Duin","year":"2020","journal-title":"Lancet Infect Dis"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2026.117578_bib0012","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1038\/s41564-019-0492-8","article-title":"Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread","volume":"4","author":"David","year":"2019","journal-title":"Nat Microbiol"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117578_bib0013","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1128\/JCM.00447-06","article-title":"Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions","volume":"44","author":"Oteo","year":"2006","journal-title":"J Clin Microbiol"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117578_bib0014","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.00128-25","article-title":"Detection of ESBL-producing Klebsiella oxytoca complex with VITEK 2 system and screening cutoffs for implementing confirmatory tests","volume":"63","author":"Campos-Madueno","year":"2025","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0015","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.04673-22","article-title":"Performance of the Vitek 2 advanced expert system (AES) as a rapid tool for reporting antimicrobial susceptibility testing (AST) in enterobacterales from North and Latin America","volume":"11","author":"Carvalhaes","year":"2023","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/9519718","article-title":"The growing genetic and functional diversity of extended spectrum beta-lactamases","volume":"2018","author":"Ur Rahman","year":"2018","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0017","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.12688\/f1000research.14822.1","article-title":"Treatment of extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae (ESBLs) infections: what have we learned until now?","volume":"7","author":"Pana","year":"2018","journal-title":"F1000Res"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2026.117578_bib0018","doi-asserted-by":"crossref","first-page":"5655","DOI":"10.1128\/AAC.00897-16","article-title":"Interaction of Avibactam with class B metallo-\u03b2-lactamases","volume":"60","author":"Abboud","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0019","series-title":"Monobactam: aztreonam","author":"Finberg","year":"2021"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0020","series-title":"CLSI. Performance standards for antimicrobial susceptibility testing. 34 ed Clinical and Laboratory Standards","year":"2024"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0021","series-title":"Breakpoint tables for interpretation of MICs and zone diameters","author":"European Committee on Antimicrobial Susceptibility Testing","year":"2022"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117578_bib0022","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1099\/ijsem.0.002809","article-title":"Using average nucleotide identity to improve taxonomic assignments in prokaryotic genomes at the NCBI","volume":"68","author":"Ciufo","year":"2018","journal-title":"Int J Syst Evol Microbiol"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117578_bib0023","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.01934-17","article-title":"CLSI methods development and standardization working group best practices for evaluation of antimicrobial susceptibility tests","volume":"56","author":"Humphries","year":"2018","journal-title":"J Clin Microbiol"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117578_bib0024","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2017.114","article-title":"Predicting attention-deficit\/hyperactivity disorder severity from psychosocial stress and stress-response genes: a random forest regression approach","volume":"7","author":"van der Meer","year":"2017","journal-title":"Transl Psychiatry"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0025","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1023\/A:1010933404324","article-title":"Random forests","volume":"45","year":"2001","journal-title":"Mach Learn"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117578_bib0026","doi-asserted-by":"crossref","first-page":"470","DOI":"10.3343\/alm.2019.39.5.470","article-title":"Performance evaluation of the newly developed BD Phoenix NMIC-500 panel using clinical isolates of gram-negative Bacilli","volume":"39","author":"Park","year":"2019","journal-title":"Ann Lab Med"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117578_bib0027","doi-asserted-by":"crossref","first-page":"2072","DOI":"10.1128\/JCM.02636-05","article-title":"Evaluation of the BD Phoenix automated microbiology system for identification and antimicrobial susceptibility testing of staphylococci and enterococci","volume":"44","author":"Carroll","year":"2006","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0028","article-title":"Performance evaluation of BD Phoenix NMIC-413 antimicrobial susceptibility testing panel for Imipenem, Meropenem, and Ertapenem against clinical carbapenem-resistant and carbapenem-susceptible enterobacterales","volume":"8","author":"Zhang","year":"2021","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0029","doi-asserted-by":"crossref","first-page":"186","DOI":"10.3390\/antibiotics9040186","article-title":"The current burden of carbapenemases: review of significant properties and dissemination among gram-negative bacteria","volume":"9","author":"Hammoudi Halat","year":"2020","journal-title":"Antibiotics (Basel)"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117578_bib0030","doi-asserted-by":"crossref","first-page":"dlab092","DOI":"10.1093\/jacamr\/dlab092","article-title":"Extended-spectrum \u03b2-lactamases: an update on their characteristics, epidemiology and detection","volume":"3","author":"Castanheira","year":"2021","journal-title":"JAC Antimicrob Resist"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0031","first-page":"98","article-title":"Nationwide surveillance of clinical carbapenem-resistant Enterobacteriaceae (CRE) strains in China","volume":"19","author":"Zhang","year":"2017","journal-title":"EBio Med"},{"issue":"11","key":"10.1016\/j.diagmicrobio.2026.117578_bib0032","doi-asserted-by":"crossref","first-page":"2833","DOI":"10.1093\/jac\/dkab279","article-title":"Investigation of mechanisms responsible for decreased susceptibility of aztreonam\/avibactam activity in clinical isolates of enterobacterales collected in Europe, Asia and Latin America in 2019","volume":"76","author":"Mendes","year":"2021","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0033","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2024.2426481","article-title":"Overexpression of bla(SHV-12) caused by tandem amplification contributed to ceftazidime\/avibactam resistance in hypervirulent and carbapenem-resistant Klebsiella pneumoniae","volume":"13","author":"Liu","year":"2024","journal-title":"Emerg Microbes Infect"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117578_bib0034","doi-asserted-by":"crossref","first-page":"124.e1","DOI":"10.1016\/j.cmi.2019.08.020","article-title":"Emergence of ceftazidime\/avibactam resistance in carbapenem-resistant Klebsiella pneumoniae in China","volume":"26","author":"Zhang","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0035","doi-asserted-by":"crossref","first-page":"6","DOI":"10.7324\/JAPS.2024.177584","article-title":"Predicting the distribution patterns of antibiotic-resistant microorganisms in the context of Jordanian cases using machine learning techniques","volume":"14","author":"Al-Khlifeh","year":"2024","journal-title":"J Appl Pharm Sci"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0036","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jgar.2022.03.003","article-title":"Epidemiology and prediction of multidrug-resistant bacteria based on hospital level","volume":"29","author":"Chen","year":"2022","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.diagmicrobio.2026.117578_bib0037","article-title":"Combination of MALDI-TOF mass spectrometry and machine learning for rapid antimicrobial resistance screening: the case of campylobacter spp","volume":"12","author":"Feucherolles","year":"2021","journal-title":"Front Microbiol"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117578_bib0038","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1002\/phar.1622","article-title":"The \u03b2-lactams strike back: ceftazidime-avibactam","volume":"35","author":"Zasowski","year":"2015","journal-title":"Pharmacotherapy"},{"issue":"8","key":"10.1016\/j.diagmicrobio.2026.117578_bib0039","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00883-17","article-title":"Ceftazidime-Avibactam is superior to other treatment regimens against carbapenem-resistant Klebsiella pneumoniae bacteremia","volume":"61","author":"Shields","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2026.117578_bib0040","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s10096-023-04645-2","article-title":"In vitro activity of aztreonam-avibactam against enterobacterales isolates collected in Latin America, Africa\/Middle East, Asia, and Eurasia for the ATLAS Global Surveillance Program in 2019-2021","volume":"42","author":"Wise","year":"2023","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326003287?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326003287?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:09:41Z","timestamp":1792066181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326003287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S0732889326003287"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117578","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of the NMIC-150 system in identifying extended-spectrum beta-lactamases in clinical isolates","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117578","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117578"}}