{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:50:15Z","timestamp":1792068615654,"version":"4.4.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.diagmicrobio.2026.117586","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:44:21Z","timestamp":1785307461000},"page":"117586","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Morbidity and mortality of respiratory syncytial virus versus influenza virus infections in hospitalized older adults: an adjusted comparative analysis"],"prefix":"10.1016","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8263-9665","authenticated-orcid":false,"given":"Alba Cano","family":"Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Garc\u00eda-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel Cano","family":"de Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117586_bib0001","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1093\/infdis\/jiae171","article-title":"Respiratory syncytial virus vs influenza virus infection: mortality and morbidity comparison over 7 epidemic seasons in an elderly population","volume":"230","author":"Recto","year":"2024","journal-title":"J Infect Dis"},{"issue":"5","key":"10.1016\/j.diagmicrobio.2026.117586_bib0002","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.70373","article-title":"Disease burden of RSV infection in adult patients in comparison to influenza virus infection","volume":"97","author":"Trifonov","year":"2025","journal-title":"J Med Virol"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0003","unstructured":"Centers for Disease Control and Prevention (CDC). Disease burden of influenza. (Actualizado anualmente)."},{"issue":"19","key":"10.1016\/j.diagmicrobio.2026.117586_bib0004","first-page":"185","article-title":"Vaccines against influenza WHO position paper - May 2022","volume":"97","year":"2022","journal-title":"Wkly Epidemiol Rec"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0005","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.medcli.2024.11.024","article-title":"Infecci\u00f3n por el virus respiratorio sincitial en adultos: \u00bfuna enfermedad olvidada?","volume":"164","author":"Cilloniz","year":"2025","journal-title":"Med Clin"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117586_bib0006","first-page":"303","article-title":"Underascertainment of respiratory syncytial virus infection in adults due to diagnostic testing limitations: a systematic literature review and meta-analysis","volume":"229","author":"Kwon","year":"2024","journal-title":"J Infect Dis"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117586_bib0007","doi-asserted-by":"crossref","first-page":"3738","DOI":"10.1128\/JCM.01816-15","article-title":"Diagnostic accuracy of rapid antigen detection tests for respiratory syncytial virus infection: systematic review and meta-analysis","volume":"53","author":"Chartrand","year":"2015","journal-title":"J Clin Microbiol"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117586_bib0008","article-title":"Evaluation of the ImmuView RSV test for rapid detection of respiratory syncytial virus in adult patients with influenza-like symptoms","volume":"61","author":"Larsson","year":"2023","journal-title":"J Clin Microbiol"},{"issue":"9","key":"10.1016\/j.diagmicrobio.2026.117586_bib0009","first-page":"765","article-title":"Addressing the underestimated burden of RSV in older adults in Europe: epidemiology, surveillance gaps, and public health implications","volume":"13","author":"Martin\u00f3n-Torres","year":"2024","journal-title":"Pathogens"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0010","article-title":"Respiratory syncytial virus-related mortality in adults compared with Influenza A and B","author":"Clausen","year":"2024","journal-title":"Open Forum Infect Dis"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117586_bib0011","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1080\/23744235.2025.2450590","article-title":"Severity and outcomes of adult respiratory syncytial virus inpatient compared with influenza: observational study from Japan","volume":"57","author":"Inoue","year":"2025","journal-title":"Infect Dis"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0012","unstructured":"Falsey AR, Walsh EE. Respiratory syncytial virus infection in older adults: clinical features and management. Clin Infect Dis.."},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0013","unstructured":"Boissier F, Lemiale V, Contou D, et al. Caracter\u00edsticas y resultados de los pacientes en la UCI con virus respiratorio sincitial en comparaci\u00f3n con aquellos con infecci\u00f3n por influenza."},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0014","article-title":"Efficacy and safety of respiratory syncytial virus vaccines","author":"Saif-Ur-Rahman","year":"2025","journal-title":"Cochrane Database System Rev"},{"issue":"29","key":"10.1016\/j.diagmicrobio.2026.117586_bib0015","doi-asserted-by":"crossref","first-page":"793","DOI":"10.15585\/mmwr.mm7229a4","article-title":"Use of Respiratory syncytial virus vaccines in older adults: recommendations of the Advisory Committee on Immunization Practices \u2014 United States, 2023","volume":"72","author":"Melgar","year":"2023","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"6158","key":"10.1016\/j.diagmicrobio.2026.117586_bib0016","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1126\/science.1243283","article-title":"Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus","volume":"342","author":"McLellan","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0018","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1056\/NEJMoa2307079","article-title":"Efficacy and safety of an mRNA-based RSV vaccine in older adults","volume":"389","author":"Wilson","year":"2023","journal-title":"N Engl J Med"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0019","series-title":"Vacunaci\u00f3n frente a virus respiratorio sincitial en poblaci\u00f3n adulta","year":"2024"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0020","series-title":"Clasificaci\u00f3n internacional de enfermedades 10.\u00aa Revisi\u00f3n, modificaci\u00f3n cl\u00ednica para Espa\u00f1a (CIE-10-ES)","year":"2022"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0021","series-title":"Arexvy (respiratory syncytial virus vaccine, recombinant, adjuvanted). EPAR - medicine overview","year":"2023"},{"key":"10.1016\/j.diagmicrobio.2026.117586_bib0022","series-title":"Calendario com\u00fan de vacunaci\u00f3n a lo largo de toda la vida","year":"2023"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117586_bib0030","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1001\/jamainternmed.2024.0212","article-title":"Acute cardiac events in hospitalized older adults with respiratory syncytial virus infection","volume":"184","author":"Woodruff","year":"2024","journal-title":"JAMA Intern Med"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117586_bib0023","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1093\/cid\/ciy991","article-title":"Severe morbidity and mortality associated with respiratory syncytial virus versus Influenza infection in hospitalized older adults","volume":"69","author":"Ackerson","year":"2019","journal-title":"Clin Infect Dis"},{"issue":"17","key":"10.1016\/j.diagmicrobio.2026.117586_bib0024","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1056\/NEJMoa043951","article-title":"Respiratory syncytial virus infection in elderly and high-risk adults","volume":"352","author":"Falsey","year":"2005","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117586_bib0025","doi-asserted-by":"crossref","first-page":"e158","DOI":"10.1093\/cid\/ciaa730","article-title":"Respiratory syncytial virus-associated hospitalizations among adults with chronic medical conditions","volume":"73","author":"Prasad","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"6","key":"10.1016\/j.diagmicrobio.2026.117586_bib0029","first-page":"612","article-title":"Comparison of clinical characteristics and outcomes in hospitalized adult patients infected with respiratory syncytial virus and influenza virus","volume":"136","author":"Kim","year":"2024","journal-title":"Postgrad Med"},{"issue":"171","key":"10.1016\/j.diagmicrobio.2026.117586_bib0031","article-title":"The risk of cardiac disease events after respiratory syncytial virus disease: a systematic literature review and meta-analysis","volume":"33","author":"Vora","year":"2024","journal-title":"Eur Respir Rev"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2026.117586_bib0026","article-title":"Clinical manifestations and outcomes in adults hospitalized with respiratory syncytial virus and influenza a\/B: a multicenter observational cohort study","volume":"11","author":"Rasmussen","year":"2024","journal-title":"Open Forum Infect Dis"},{"issue":"40","key":"10.1016\/j.diagmicrobio.2026.117586_bib0027","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.15585\/mmwr.mm7240a2","article-title":"Disease severity of Respiratory syncytial virus compared with COVID-19 and influenza among hospitalized adults aged \u226560 years \u2014 IVY Network, 20 U.S. States, February 2022\u2013May 2023","volume":"72","author":"Surie","year":"2023","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117586_bib0028","first-page":"605","article-title":"A comparison of clinical characteristics and mortality in hospitalised patients with respiratory syncytial virus and influenza virus infections: a cohort study","volume":"58","author":"Gubbels","year":"2026","journal-title":"Infect Dis"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326003366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326003366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:09:54Z","timestamp":1792066194000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326003366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S0732889326003366"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117586","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morbidity and mortality of respiratory syncytial virus versus influenza virus infections in hospitalized older adults: an adjusted comparative analysis","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117586","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117586"}}