{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:53:50Z","timestamp":1791914030713,"version":"4.3.4"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Microbiology and Infectious Disease"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.diagmicrobio.2026.117686","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:20:31Z","timestamp":1791588031000},"page":"117686","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Detection of Efflux mediated drug resistance in clinical isolates of Acinetobacter baumannii in a tertiary care hospital"],"prefix":"10.1016","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9869-9774","authenticated-orcid":false,"given":"Priyadharsini","family":"Tamilselvan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2670-4773","authenticated-orcid":false,"given":"Lavanya","family":"Sriramajayam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Appalaraju","family":"Boppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamadiya Rizwana","family":"M","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0001","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/595011","article-title":"Bad bugs, no drugs: no ESKAPE! an update from the infectious diseases society of America","volume":"48","author":"Boucher","year":"2009","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0002","first-page":"47","article-title":"Antibiotic resistance determinants in nosocomial strains of multidrug-resistant Acinetobacter baumannii","volume":"63","author":"Mak","year":"2009","journal-title":"J AntimicrobChemother"},{"key":"10.1016\/j.diagmicrobio.2026.117686_bib0003","series-title":"WHO Bacterial Priority Pathogens List 2024 Bacterial Pathogens of Public Health Importance, to Guide Research, Development, and Strategies to Prevent and Control Antimicrobial Resistance","year":"2024"},{"issue":"01","key":"10.1016\/j.diagmicrobio.2026.117686_bib0004","doi-asserted-by":"crossref","first-page":"085","DOI":"10.1055\/s-0034-1398388","article-title":"Acinetobacter baumannii: evolution of antimicrobial resistance\u2014treatment options","volume":"36","author":"Doi","year":"2015","journal-title":"Semin Respir Crit Care Med"},{"key":"10.1016\/j.diagmicrobio.2026.117686_bib0005","series-title":"Advances in Microbiology, Infectious Diseases and Public Health [Internet]","article-title":"Different efflux pump systems in acinetobacter baumannii and their role in multidrug resistance","author":"Sharma","year":"2023"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117686_bib0006","doi-asserted-by":"crossref","DOI":"10.1128\/msystems.00217-22","article-title":"Differential binding of carbapenems with the AdeABC efflux pump and modulation of the expression of AdeB linked to novel mutations within two-component system AdeRS in carbapenem-resistant acinetobacter baumannii","volume":"7","author":"Roy","year":"2022","journal-title":"mSystems"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2026.117686_bib0007","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.19048","article-title":"Efflux pump inhibitor phenylalanine-arginine \u03b2-naphthylamide effect on the minimum inhibitory concentration of imipenem in acinetobacter baumannii strains isolated from hospitalized patients in shahid motahari burn hospital, Tehran, Iran","volume":"8","author":"Gholami","year":"2015","journal-title":"Jundishapur J Microbiol"},{"issue":"12","key":"10.1016\/j.diagmicrobio.2026.117686_bib0008","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0259915","article-title":"The effect of the efflux pump inhibitor carbonyl cyanide m-chlorophenylhydrazone (CCCP) on the susceptibility to imipenem and cefepime in clinical strains of Acinetobacter baumannii","volume":"16","author":"Sanchez-Carbonel","year":"2021","journal-title":"PLOS ONE"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117686_bib0009","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0010","doi-asserted-by":"crossref","first-page":"72","DOI":"10.2174\/1874285801307010072","article-title":"A simple method for assessment of mdr bacteria for over-expressed efflux pumps","volume":"7","author":"Martins","year":"2013","journal-title":"Open Microbiol J"},{"key":"10.1016\/j.diagmicrobio.2026.117686_bib0011","series-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard \u2013 Tenth Edition. CLSI document M07-A10","year":"2015"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117686_bib0012","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4103\/ijmr.IJMR_2079_17","article-title":"Efflux pump inhibitors for bacterial pathogens: from bench to bedside","volume":"149","author":"Sharma","year":"2019","journal-title":"Indian J Med Res"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0013","doi-asserted-by":"crossref","DOI":"10.5812\/jjm.8691","article-title":"Effect of efflux pump inhibitor carbonyl cyanide 3-chlorophenylhydrazone on the minimum inhibitory concentration of ciprofloxacin in acinetobacter baumannii clinical isolates","volume":"7","author":"Ardebili","year":"2014","journal-title":"Jundishapur J Microbiol"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0014","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ijantimicag.2008.06.027","article-title":"Distribution of the multidrug efflux pump genes, adeABC, adeDE and adeIJK, and class 1 integron genes in multiple-antimicrobial-resistant clinical isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus complex","volume":"33","author":"Lin","year":"2009","journal-title":"Int J Antimicrob Agents"},{"issue":"7","key":"10.1016\/j.diagmicrobio.2026.117686_bib0015","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.3390\/vaccines11071171","article-title":"The prevalence of multidrug-resistant acinetobacter baumannii and its vaccination status among healthcare providers","volume":"11","author":"Elbehiry","year":"2023","journal-title":"Vaccines"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0016","doi-asserted-by":"crossref","first-page":"36","DOI":"10.52547\/JoMMID.10.1.36","article-title":"Detection of efflux pump using ethidium bromide-agar cartwheel method in acinetobacter baumannii clinical isolates","volume":"10","author":"Sepehr","year":"2022","journal-title":"JoMMID"},{"issue":"2","key":"10.1016\/j.diagmicrobio.2026.117686_bib0017","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000335599","article-title":"Study of the correlation of imipenem resistance with efflux pumps AdeABC, AdeIJK, AdeDE and AbeM in clinical isolates of Acinetobacter baumannii","volume":"58","author":"Hou","year":"2012","journal-title":"Chemotherapy"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0018","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s13756-021-00924-9","article-title":"Characteristics and diversity of mutations in regulatory genes of resistance-nodulation-cell division efflux pumps in association with drug-resistant clinical isolates of Acinetobacter baumannii","volume":"10","author":"Salehi","year":"2021","journal-title":"Antimicrob Resist Infect Control"},{"issue":"10","key":"10.1016\/j.diagmicrobio.2026.117686_bib0019","doi-asserted-by":"crossref","first-page":"4389","DOI":"10.1128\/AAC.00155-10","article-title":"Overexpression of resistance-nodulation-cell division pump AdeFGH confers multidrug resistance in Acinetobacter baumannii","volume":"54","author":"Coyne","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"issue":"4","key":"10.1016\/j.diagmicrobio.2026.117686_bib0020","doi-asserted-by":"crossref","first-page":"229","DOI":"10.4103\/0975-7406.142949","article-title":"Detection of AdeABC efflux pump genes in tetracycline-resistant Acinetobacter baumannii isolates from burn and ventilator-associated pneumonia patients","volume":"6","author":"Beheshti","year":"2014","journal-title":"J Pharm Bioallied Sci"},{"issue":"1","key":"10.1016\/j.diagmicrobio.2026.117686_bib0021","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1186\/s13104-020-05387-6","article-title":"Antibiotic resistance assessment of Acinetobacter baumannii isolates from Tehran hospitals due to the presence of efflux pumps encoding genes (adeA and adeS genes) by molecular method","volume":"13","author":"Basatian-Tashkan","year":"2020","journal-title":"BMC Res Notes"},{"issue":"3","key":"10.1016\/j.diagmicrobio.2026.117686_bib0022","first-page":"483","article-title":"Relationship between the AdeABC efflux system gene content, netilmicin susceptibility and multidrug resistance in a genotypically diverse collection of Acinetobacter baumannii strains","volume":"60","author":"Nemec","year":"2007","journal-title":"J AntimicrobChemother"}],"container-title":["Diagnostic Microbiology and Infectious Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326004372?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0732889326004372?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T17:32:52Z","timestamp":1791912772000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0732889326004372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2027,1]]}},"alternative-id":["S0732889326004372"],"URL":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117686","relation":{},"ISSN":["0732-8893"],"issn-type":[{"value":"0732-8893","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of Efflux mediated drug resistance in clinical isolates of Acinetobacter baumannii in a tertiary care hospital","name":"articletitle","label":"Article Title"},{"value":"Diagnostic Microbiology and Infectious Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diagmicrobio.2026.117686","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117686"}}