{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:00:53Z","timestamp":1786114853420,"version":"build-2736575974"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002920","name":"University Grants Committee Research Grants Council","doi-asserted-by":"publisher","award":["15304819"],"award-info":[{"award-number":["15304819"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Data in Brief"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.dib.2026.113045","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T23:35:17Z","timestamp":1783035317000},"page":"113045","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Comprehensive characterization of myopic guinea pigs' retina following PI3K\/AKT inhibition using a data-independent acquisition dataset on an Orbitrap Exploris 480 mass spectrometer"],"prefix":"10.1016","volume":"67","author":[{"given":"Hu","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2239-1981","authenticated-orcid":false,"given":"Oi Ying","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4146-0770","authenticated-orcid":false,"given":"Man Hin","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3183-8012","authenticated-orcid":false,"given":"Jimmy Ka-Wai","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2804-2424","authenticated-orcid":false,"given":"Da Qian","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6978-0963","authenticated-orcid":false,"given":"Rachel Ka Man","family":"Chun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing Fang","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3511-5620","authenticated-orcid":false,"given":"Thomas Chuen","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dib.2026.113045_bib0001","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/s41572-020-00231-4","article-title":"Myopia","volume":"6","author":"Baird","year":"2020","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.dib.2026.113045_bib0002","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1167\/iovs.62.5.3","article-title":"IMI risk factors for myopia","volume":"62","author":"Morgan","year":"2021","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.dib.2026.113045_bib0003","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.ophtha.2021.04.032","article-title":"The risks and benefits of myopia control","volume":"128","author":"Bullimore","year":"2021","journal-title":"Ophthalmology"},{"key":"10.1016\/j.dib.2026.113045_bib0004","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/opo.13366","article-title":"High myopia: reviews of myopia control strategies and myopia complications","volume":"44","author":"Shah","year":"2024","journal-title":"Ophthalmic Physiol. Opt."},{"key":"10.1016\/j.dib.2026.113045_bib0005","article-title":"Covariation of scleral remodeling and PI3K\/akt signaling pathway in experimental myopia","volume":"15","author":"Li","year":"2025","journal-title":"Sci. Rep."},{"key":"10.1016\/j.dib.2026.113045_bib0006","article-title":"Reduction of experimental ocular axial elongation by neuregulin-1 antibody","volume":"10","author":"Shi","year":"2023","journal-title":"Front Med. (Lausanne)"},{"key":"10.1016\/j.dib.2026.113045_bib0007","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1167\/iovs.64.4.11","article-title":"Intravitreal short-hairpin RNA attenuated adeno-associated virus-induced knockdown of amphiregulin and axial elongation in experimental myopia","volume":"64","author":"Dong","year":"2023","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.dib.2026.113045_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166981","article-title":"Targeting scleral remodeling and myopia development in form deprivation myopia through inhibition of EFEMP1 expression","volume":"1870","author":"Shi","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.dib.2026.113045_bib0009","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1186\/s12886-021-01946-y","article-title":"PI3K\/AKT\/mTOR signaling participates in insulin-mediated regulation of pathological myopia-related factors in retinal pigment epithelial cells","volume":"21","author":"Li","year":"2021","journal-title":"BMC Ophthalmol."},{"key":"10.1016\/j.dib.2026.113045_bib0010","article-title":"Association of myopia and genetic variants of TGFB2-AS1 and TGFBR1 in the TGF-\u03b2 signaling pathway: a longitudinal study in Chinese school-aged children","volume":"9","author":"Liu","year":"2021","journal-title":"Front Cell Dev. Biol."},{"key":"10.1016\/j.dib.2026.113045_bib0011","doi-asserted-by":"crossref","first-page":"5859","DOI":"10.1038\/s41467-022-33605-1","article-title":"Scleral PERK and ATF6 as targets of myopic axial elongation of mouse eyes","volume":"13","author":"Ikeda","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.dib.2026.113045_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2023.12.023","article-title":"Augmentation of scleral glycolysis promotes myopia through histone lactylation","volume":"36","author":"Lin","year":"2024","journal-title":"Cell Metab."},{"key":"10.1016\/j.dib.2026.113045_bib0013","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s10565-025-10020-y","article-title":"Sodium fluoride promotes myopia progression via the activation of the ferroptosis pathway by PIEZO1 and pharmacological targeting PIEZO1 represents an innovative approach for myopia treatment","volume":"41","author":"Liu","year":"2025","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.dib.2026.113045_bib0014","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/s41587-022-01389-w","article-title":"Increasing the throughput of sensitive proteomics by plexDIA","volume":"41","author":"Derks","year":"2023","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.dib.2026.113045_bib0015","doi-asserted-by":"crossref","first-page":"3944","DOI":"10.1038\/s41467-022-31492-0","article-title":"dia-PASEF data analysis using FragPipe and DIA-NN for deep proteomics of low sample amounts","volume":"13","author":"Demichev","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.dib.2026.113045_bib0016","doi-asserted-by":"crossref","first-page":"5399","DOI":"10.1038\/s41467-021-25454-1","article-title":"Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale","volume":"12","author":"Steger","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.dib.2026.113045_bib0017","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41592-019-0638-x","article-title":"DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput","volume":"17","author":"Demichev","year":"2020","journal-title":"Nat. Method."},{"key":"10.1016\/j.dib.2026.113045_bib0018","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1021\/acs.jproteome.2c00513","article-title":"MS-DAP platform for downstream data analysis of label-free proteomics uncovers optimal workflows in benchmark data sets and increased sensitivity in analysis of alzheimer\u2019s biomarker data","volume":"22","author":"Koopmans","year":"2023","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.dib.2026.113045_bib0019","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.3390\/cells10071588","article-title":"Age-dependent hippocampal proteomics in the APP\/PS1 alzheimer mouse model: a comparative analysis with classical SWATH\/DIA and directDIA approaches","volume":"10","author":"van der Spek","year":"2021","journal-title":"Cells"}],"container-title":["Data in Brief"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352340926005937?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352340926005937?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T22:06:31Z","timestamp":1785967591000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352340926005937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":19,"alternative-id":["S2352340926005937"],"URL":"https:\/\/doi.org\/10.1016\/j.dib.2026.113045","relation":{"is-supplemented-by":[{"id-type":"uri","id":"https:\/\/www.ebi.ac.uk\/pride","asserted-by":"subject"}]},"ISSN":["2352-3409"],"issn-type":[{"value":"2352-3409","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comprehensive characterization of myopic guinea pigs' retina following PI3K\/AKT inhibition using a data-independent acquisition dataset on an Orbitrap Exploris 480 mass spectrometer","name":"articletitle","label":"Article Title"},{"value":"Data in Brief","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dib.2026.113045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"113045"}}