{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T23:12:52Z","timestamp":1768518772212,"version":"3.49.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"vor","delay-in-days":366,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic and Interventional Imaging"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.diii.2015.03.006","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T09:20:20Z","timestamp":1430212820000},"page":"915-922","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["MRI versus histological methods for time course monitoring of steatosis amount in a murine model of NAFLD"],"prefix":"10.1016","volume":"96","author":[{"given":"L.-M.","family":"Leiber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Boursier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Michalak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Roullier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Fizanne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Chaigneau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Roux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Moal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Flamment","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Bazeries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.-H.","family":"Ducluzeau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Aube","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.diii.2015.03.006_bib0190","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1111\/j.1365-2036.2007.03246.x","article-title":"GI Epidemiology: nonalcoholic fatty liver disease: GI Epidemiology: nonalcoholic fatty liver disease","volume":"25","author":"Angulo","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.diii.2015.03.006_bib0195","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/hep.20734","article-title":"Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study","volume":"42","author":"Bedogni","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.diii.2015.03.006_bib0200","doi-asserted-by":"crossref","first-page":"S99","DOI":"10.1002\/hep.20973","article-title":"Nonalcoholic fatty liver disease: from steatosis to cirrhosis","volume":"43","author":"Farrell","year":"2006","journal-title":"Hepatology"},{"key":"10.1016\/j.diii.2015.03.006_bib0205","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1161\/ATVBAHA.107.147538","article-title":"Fatty Liver: a novel component of the metabolic syndrome","volume":"28","author":"Kotronen","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.diii.2015.03.006_bib0210","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.dld.2010.01.016","article-title":"From the metabolic syndrome to NAFLD or vice versa?","volume":"42","author":"Vanni","year":"2010","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.diii.2015.03.006_bib0215","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.diii.2013.04.006","article-title":"Quantification of the visceral and subcutaneous fat by computed tomography: interobserver correlation of a single slice technique","volume":"94","author":"Sottier","year":"2013","journal-title":"Diagn Interv Imaging"},{"key":"10.1016\/j.diii.2015.03.006_bib0220","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1053\/jhep.2003.50161","article-title":"Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome","volume":"37","author":"Marchesini","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.diii.2015.03.006_bib0225","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/ncpendmet0190","article-title":"Mechanisms of disease: hepatic steatosis in type 2 diabetes\u2013pathogenesis and clinical relevance","volume":"2","author":"Roden","year":"2006","journal-title":"Nat Clin Pract Endocrinol Metab"},{"key":"10.1016\/j.diii.2015.03.006_bib0230","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.2174\/138161207781039652","article-title":"Non-alcoholic fatty liver disease in the metabolic syndrome","volume":"13","author":"Palasciano","year":"2007","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.diii.2015.03.006_bib0235","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1053\/j.gastro.2005.04.014","article-title":"The natural history of nonalcoholic fatty liver disease: a population-based cohort study","volume":"129","author":"Adams","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.diii.2015.03.006_bib0240","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1097\/MEG.0b013e32834a4d82","article-title":"Steatosis degree, measured by morphometry, is linked to other liver lesions and metabolic syndrome components in patients with NAFLD","volume":"23","author":"Boursier","year":"2011","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.diii.2015.03.006_bib0245","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.biocel.2008.10.027","article-title":"Non-alcoholic steatohepatitis and animal models: understanding the human disease","volume":"41","author":"Varela-Rey","year":"2009","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.diii.2015.03.006_bib0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.0959-9673.2006.00465.x","article-title":"Mouse models in non-alcoholic fatty liver disease and steatohepatitis research: mouse models in NAFLD and NASH research","volume":"87","author":"Anstee","year":"2006","journal-title":"Int J Exp Pathol"},{"key":"10.1016\/j.diii.2015.03.006_bib0255","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1172\/JCI20513","article-title":"Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas","volume":"113","author":"Horie","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.diii.2015.03.006_bib0260","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1096\/fj.02-0078fje","article-title":"Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A","volume":"16","author":"Mart\u00ednez-Chantar","year":"2002","journal-title":"FASEB J"},{"key":"10.1016\/j.diii.2015.03.006_bib0265","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1538\/expanim.56.263","article-title":"Involvement of sex, strain and age factors in high fat diet-induced obesity in C57BL\/6J and BALB\/cA Mice","volume":"56","author":"Nishikawa","year":"2007","journal-title":"Exp Anim"},{"key":"10.1016\/j.diii.2015.03.006_bib0270","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/ajcn\/79.3.502","article-title":"Model of nonalcoholic steatohepatitis","volume":"79","author":"Lieber","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.diii.2015.03.006_bib0275","doi-asserted-by":"crossref","first-page":"S215","DOI":"10.2337\/diabetes.53.suppl_3.S215","article-title":"The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes","volume":"53","author":"Winzell","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.diii.2015.03.006_bib0280","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1002\/hep.20877","article-title":"Steatohepatitis induced by intragastric overfeeding in mice","volume":"42","author":"Deng","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.diii.2015.03.006_bib0285","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cld.2007.02.010","article-title":"Pathogenesis of NASH: animal models","volume":"11","author":"London","year":"2007","journal-title":"Clin Liver Dis"},{"key":"10.1016\/j.diii.2015.03.006_bib0290","doi-asserted-by":"crossref","first-page":"e24084","DOI":"10.1371\/journal.pone.0024084","article-title":"Oxidation of Hepatic carnitine palmitoyl transferase-I (CPT-I) impairs fatty acid beta-oxidation in rats fed a methionine-choline deficient diet","volume":"6","author":"Serviddio","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.diii.2015.03.006_bib0295","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1053\/j.gastro.2005.03.084","article-title":"Sampling variability of liver biopsy in nonalcoholic fatty liver disease","volume":"128","author":"Ratziu","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.diii.2015.03.006_bib0300","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1002\/hep.24452","article-title":"Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis","volume":"54","author":"Hernaez","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.diii.2015.03.006_bib0305","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.diii.2013.03.010","article-title":"Hepatic steatosis: a major trap in liver imaging","volume":"94","author":"Vilgrain","year":"2013","journal-title":"Diagn Interv Imaging"},{"key":"10.1016\/j.diii.2015.03.006_bib0310","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1148\/rg.291075123","article-title":"Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis 1","volume":"29","author":"Cassidy","year":"2009","journal-title":"RadioGraphics"},{"key":"10.1016\/j.diii.2015.03.006_bib0315","article-title":"Quantification of hepatic steatosis: a comparison of the accuracy among multiple magnetic resonance techniques","author":"Wu","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.diii.2015.03.006_bib0320","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.diabet.2013.01.007","article-title":"MRI measurement of liver fat content predicts the metabolic syndrome","volume":"39","author":"Ducluzeau","year":"2013","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.diii.2015.03.006_bib0325","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1002\/hep.21655","article-title":"Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis","volume":"45","author":"Yamaguchi","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.diii.2015.03.006_bib0330","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1016\/S0221-0363(09)73268-8","article-title":"Fast technique to quantify liver steatosis at 3T: principles, parametric imaging and applications","volume":"90","author":"Guiu","year":"2009","journal-title":"J Radiol"},{"key":"10.1016\/j.diii.2015.03.006_bib0335","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.bbrc.2006.08.071","article-title":"Hepatic knockdown of mitochondrial GPAT1 in ob\/ob mice improves metabolic profile","volume":"349","author":"Xu","year":"2006","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.diii.2015.03.006_bib0340","first-page":"5575","article-title":"Fuzzy algorithms to extract vacuoles of steatosis on liver histological color images","author":"Roullier","year":"2007","journal-title":"Conf Proc IEEE Eng Med Biol Soc"},{"key":"10.1016\/j.diii.2015.03.006_bib0345","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0168-8278(98)80318-8","article-title":"Histopathological evaluation of liver fibrosis: quantitative image analysis vs semi-quantitative scores. Comparison with serum markers","volume":"28","author":"Pilette","year":"1998","journal-title":"J Hepatol"},{"key":"10.1016\/j.diii.2015.03.006_bib0350","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.jhep.2013.05.044","article-title":"From NAFLD in clinical practice to answers from guidelines","volume":"59","author":"Nascimbeni","year":"2013","journal-title":"J Hepatol"},{"issue":"2","key":"10.1016\/j.diii.2015.03.006_bib0355","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/jmri.24153","article-title":"Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI","volume":"39","author":"Johnson","year":"2014","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.diii.2015.03.006_bib0360","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/mrm.21301","article-title":"Fat quantification with IDEAL gradient echo imaging: correction of bias from T(1) and noise","volume":"58","author":"Liu","year":"2007","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.diii.2015.03.006_bib0365","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.mric.2010.08.013","article-title":"Quantification of liver fat with magnetic resonance imaging","volume":"18","author":"Reeder","year":"2010","journal-title":"Magn Reson Imaging Clin N Am"},{"key":"10.1016\/j.diii.2015.03.006_bib0370","doi-asserted-by":"crossref","first-page":"e7408","DOI":"10.1371\/journal.pone.0007408","article-title":"Chemical imaging on liver steatosis using synchrotron infrared and ToF-SIMS microspectroscopies","volume":"4","author":"Le Naour","year":"2009","journal-title":"PLoS One"}],"container-title":["Diagnostic and Interventional Imaging"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211568415001308?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211568415001308?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,24]],"date-time":"2019-08-24T02:00:59Z","timestamp":1566612059000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211568415001308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S2211568415001308"],"URL":"https:\/\/doi.org\/10.1016\/j.diii.2015.03.006","relation":{},"ISSN":["2211-5684"],"issn-type":[{"value":"2211-5684","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MRI versus histological methods for time course monitoring of steatosis amount in a murine model of NAFLD","name":"articletitle","label":"Article Title"},{"value":"Diagnostic and Interventional Imaging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.diii.2015.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 \u00c9ditions fran\u00e7aises de radiologie. Published by Elsevier Masson SAS All rights reserved.","name":"copyright","label":"Copyright"}]}}