{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:05:14Z","timestamp":1790726714773,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Disease-a-Month"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.disamonth.2018.09.011","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T18:25:31Z","timestamp":1540837531000},"page":"185-192","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":141,"title":["Effects of periodontal disease on systemic health"],"prefix":"10.1016","volume":"65","author":[{"given":"R.","family":"Hegde","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.H.","family":"Awan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.disamonth.2018.09.011_bib0001","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1177\/0022034512457373","article-title":"Prevalence of periodontitis in adults in the United States: 2009 and 2010","volume":"91","author":"Eke","year":"2012","journal-title":"J Dent Res"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0002","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis \u2013 an infl ammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"issue":"June","key":"10.1016\/j.disamonth.2018.09.011_bib0003","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1111\/j.1600-0757.1994.tb00020.x","article-title":"Microbial etiological agents of destructive periodontal diseases","volume":"5","author":"Haffajee","year":"1994","journal-title":"Periodontol 2000"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0004","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1086\/314602","article-title":"Elevated serum cytokines are associated with cytomegalovirus infection and disease in bone marrow transplant recipients","volume":"179","author":"Humar","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0005","first-page":"264","article-title":"Two types of septicshock classified by the plasma levels of cytokines and endotoxin","volume":"38","author":"Endo","year":"1992","journal-title":"Circ Shock"},{"issue":"April (Suppl 14)","key":"10.1016\/j.disamonth.2018.09.011_bib0006","first-page":"S30","article-title":"Periodontal bacterial invasion and infection: contribution to atherosclerotic pathology","volume":"40","author":"Reyes","year":"2013","journal-title":"J Clin Periodontol"},{"issue":"April(4 Suppl)","key":"10.1016\/j.disamonth.2018.09.011_bib0007","first-page":"S51","article-title":"Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases","volume":"84","author":"Schenkein","year":"2013","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0008","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/362801a0","article-title":"The pathogenesis of atherosclerosis: a perspective for the 1990s","volume":"362","author":"Ross","year":"1993","journal-title":"Nature"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0009","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1161\/01.ATV.16.8.1000","article-title":"Interleukin-1 beta in coronary arteriesof patients with ischemic heart disease","volume":"16","author":"Galea","year":"1996","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0010","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0002-9149(90)90291-8","article-title":"Detection and localization of tumor necrosis factor in human atheroma","volume":"65","author":"Barath","year":"1990","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0011","first-page":"503","article-title":"Tumor necrosis factor gene expression in human vascular intimal smooth muscle cells detectedby in situ hybridization","volume":"137","author":"Barath","year":"1990","journal-title":"Am J Pathol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0012","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/oxfordjournals.aje.a010203","article-title":"Examination of the relation between periodontal health status and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, Creactive protein, and plasma fi brinogen","volume":"151","author":"Wu","year":"2000","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0013","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1902\/jop.2000.71.10.1554","article-title":"Identifi cation of periodontal pathogens in atheromatous plaques","volume":"71","author":"Haraszthy","year":"2000","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0014","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1902\/jop.2005.76.5.731","article-title":"Identification of periodontal pathogens in atherosclerotic vessels","volume":"76","author":"Fiehn","year":"2005","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0015","doi-asserted-by":"crossref","first-page":"755","DOI":"10.2105\/AJPH.94.5.755","article-title":".Oral disease burden in Northern Manhattan patients with diabetes mellitus","volume":"94","author":"Lalla","year":"2004","journal-title":"Am J Public Health"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0016","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1161\/01.STR.0000155734.34652.6c","article-title":"Radiographic measures of chronic periodontitis and carotid artery plaque","volume":"36","author":"Engebretson","year":"2005","journal-title":"Stroke"},{"issue":"April (4 Suppl)","key":"10.1016\/j.disamonth.2018.09.011_bib0017","first-page":"S24","article-title":"Periodontitis and atherosclerotic cardiovascular disease: consensus report of the joint EFP\/AAP workshop on periodontitis and systemic diseases","volume":"84","author":"Tonetti","year":"2013","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0018","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1056\/NEJM200005183422007","article-title":"Intrauterine infection and preterm delivery","volume":"342","author":"Goldenberg","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0019","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1056\/NEJMe068210","article-title":"Preterm birth and periodontal disease","volume":"355","author":"Goldenberg","year":"2006","journal-title":"N Engl J Med"},{"issue":"October(4)","key":"10.1016\/j.disamonth.2018.09.011_bib0020","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/01.AOG.0000139836.47777.6d","article-title":"Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth","volume":"104","author":"Goepfert","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0021","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1902\/annals.2001.6.1.153","article-title":"The relationship between infections and adverse pregnancy outcomes: an overview","volume":"6","author":"Gibbs","year":"2001","journal-title":"Ann Periodontol"},{"issue":"10","key":"10.1016\/j.disamonth.2018.09.011_bib0034b","doi-asserted-by":"crossref","first-page":"4356","DOI":"10.1128\/iai.62.10.4356-4361.1994","article-title":"Effects of a Porphyromonas gingivalis infection on inflammatory mediator response and pregnancy outcome in hamsters","volume":"62","author":"Collins","year":"1994","journal-title":"Infect Immun."},{"issue":"10","key":"10.1016\/j.disamonth.2018.09.011_bib0034v","doi-asserted-by":"crossref","first-page":"4652","DOI":"10.1128\/iai.62.10.4652-4655.1994","article-title":"Effects of Escherichia coli and Porphyromonas gingivalis lipopolysaccharide on pregnancy outcome in the golden hamster","volume":"62","author":"Collins","year":"1994","journal-title":"Infect Immun."},{"key":"10.1016\/j.disamonth.2018.09.011_bib0022","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1902\/jop.2007.060201","article-title":"Persistently high levels of periodontal pathogens associated with preterm pregnancy outcome","volume":"78","author":"Lin","year":"2007","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0023","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.ajog.2005.05.050","article-title":"Fetal immune response to oral pathogens and risk of preterm birth","volume":"193","author":"Boggess","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0024","first-page":"1103","article-title":"Periodontal infection as a possible risk factor for preterm low birth weight","volume":"67","author":"Offenbacher","year":"1996","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0025","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1902\/jop.2001.72.11.1491","article-title":"The association between Porphyromonas gingivalis-specifi c maternal serum IgG and low birth weight","volume":"72","author":"Dasanayake","year":"2001","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0026","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1111\/j.1479-828X.2004.00323.x","article-title":"Periodontal disease as a risk factor for pre-eclampsia: a case control study","volume":"44","author":"Canakci","year":"2004","journal-title":"Aust N Z J Obs Gynaecol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0027","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/01.AOG.0000139836.47777.6d","article-title":"Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth","volume":"104","author":"Goepfert","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0028","doi-asserted-by":"crossref","first-page":"40","DOI":"10.5005\/jcdp-5-2-40","article-title":"The prevalence and relationship between periodontal disease and pre-term low birth weight infants at King Khalid University Hospital in Riyadh, Saudi Arabia","volume":"5","author":"Mokeem","year":"2004","journal-title":"J Contemp Dent Pract"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0029","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1111\/j.1600-051X.2004.00564.x","article-title":"A possible association between preterm birth andearly periodontitis. A pilot study","volume":"31","author":"Radnai","year":"2004","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0030","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1600-051X.2005.00670.x","article-title":"Periodontal infections and pre-term low birth weight: a case-control study","volume":"32","author":"Buduneli","year":"2005","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0031","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1177\/154405910208100505","article-title":"Maternal periodontaldisease and preterm low birthweight: case-control study","volume":"81","author":"Davenport","year":"2002","journal-title":"J Dent Res"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0032","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-051X.2004.00598.x","article-title":"A case-control study to investigate an association between adverse pregnancy outcome and periodontal disease","volume":"32","author":"Moore","year":"2005","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0033","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1902\/jop.2005.76.11-S.2075","article-title":"A proposed model linking inflammation to obesity, diabetes and periodontal infections","volume":"76","author":"Genco","year":"2005","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0034","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1902\/jop.2000.72.9.1221","article-title":"Periodontal infections contribute to elevated systemic C-reactive protein level","volume":"72","author":"Noack","year":"2001","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0035","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1902\/jop.2000.71.10.1528","article-title":"C-reactive protein and other markers of systemic inflammation in relation to cardiovascular diseases are elevated in periodontitis","volume":"71","author":"Loos","year":"2000","journal-title":"J Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0036","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/oxfordjournals.aje.a010203","article-title":"Examination of the relation between periodontal health status and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, C-reactive protein, and plasma fibrinogen","volume":"151","author":"Wu","year":"2000","journal-title":"Am J Epidemiol"},{"issue":"10 Suppl","key":"10.1016\/j.disamonth.2018.09.011_bib0037","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1902\/jop.1996.67.10s.1085","article-title":"Severe periodontitis and risk for poor glycemic control in patients with noninsulin- dependent diabetes mellitus","volume":"67","author":"Taylor","year":"1996","journal-title":"J Periodontol"},{"issue":"June (6)","key":"10.1016\/j.disamonth.2018.09.011_bib0038","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1177\/154405910408300610","article-title":"The severity of periodontal disease is associated with the development of glucose intolerance in non-diabetics: the Hisayama study","volume":"83","author":"Saito","year":"2004","journal-title":"J Dent Res"},{"issue":"2","key":"10.1016\/j.disamonth.2018.09.011_bib0034a","doi-asserted-by":"crossref","first-page":"615","DOI":"10.2337\/diacare.27.2.615","article-title":"Relationship between periodontal disease and diabetic retinopathy","volume":"27","author":"Norma","year":"2004","journal-title":"Diabetes Care."},{"key":"10.1016\/j.disamonth.2018.09.011_bib0039","doi-asserted-by":"crossref","first-page":"27","DOI":"10.2337\/diacare.28.1.27","article-title":"Periodontal disease and mortality in Type 2 diabetes","volume":"28","author":"Saremi","year":"2005","journal-title":"Diabetes Care"},{"issue":"February(2)","key":"10.1016\/j.disamonth.2018.09.011_bib0040","doi-asserted-by":"crossref","first-page":"306","DOI":"10.2337\/dc06-1184","article-title":"Effect of periodontitis on overt nephropathy and end-stage renal disease in type 2 diabetes","volume":"30","author":"Shultis","year":"2007","journal-title":"Diabetes Care"},{"issue":"July(7)","key":"10.1016\/j.disamonth.2018.09.011_bib0041","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.2337\/dc08-0026","article-title":"Periodontal disease and incident type 2 diabetes: results from the First National Health and Nutrition Examination Survey and its epidemiologic follow-up study","volume":"31","author":"Demmer","year":"2008","journal-title":"Diabetes Care"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0042","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1902\/jop.2010.090594","article-title":"A cohort study on the association between periodontal disease and the development of metabolic syndrome","volume":"81","author":"Morita","year":"2010","journal-title":"J Periodontol"},{"issue":"May (5)","key":"10.1016\/j.disamonth.2018.09.011_bib0043","first-page":"1037","article-title":"Periodontal status and A1C change: longitudinal results from the study of health in Pomerania (SHIP)","volume":"33","author":"Emmer","year":"2010","journal-title":"Diabetes Care"},{"issue":"October (1)","key":"10.1016\/j.disamonth.2018.09.011_bib0044","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.diabres.2010.06.014","article-title":"Periodontal disease and risk for neuropathic foot ulceration in type 2 diabetes","volume":"90","author":"Abrao","year":"2010","journal-title":"Diabetes Res Clin Pract"},{"issue":"May(1)","key":"10.1016\/j.disamonth.2018.09.011_bib0045","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.atherosclerosis.2012.01.026","article-title":"Periodontitis and diabetes associations with measures of atherosclerosis and CHD","volume":"222","author":"Southerland","year":"2012","journal-title":"Atherosclerosis"},{"issue":"April(4)","key":"10.1016\/j.disamonth.2018.09.011_bib0046","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1034\/j.1600-051x.2001.028004306.x","article-title":"The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus","volume":"28","author":"Stewart","year":"2001","journal-title":"J Clin Periodontol"},{"issue":"(Spec Iss B","key":"10.1016\/j.disamonth.2018.09.011_bib0047","article-title":"Evaluation of influence of conventional therapy in diabetics type 2","volume":"84","author":"Calbacho","year":"2004","journal-title":"J Dent Res"},{"issue":"September (5)","key":"10.1016\/j.disamonth.2018.09.011_bib0048","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/j.1601-0825.2005.01119.x","article-title":"The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects","volume":"11","author":"Promsudthi","year":"2005","journal-title":"Oral Dis"},{"issue":"1-2","key":"10.1016\/j.disamonth.2018.09.011_bib0049","first-page":"32","article-title":"Effect of non-surgical periodontal therapy on patients with type 2 diabetes mellitus","volume":"49","author":"Yun","year":"2007","journal-title":"Folia Med (Plovdiv)"},{"issue":"1","key":"10.1016\/j.disamonth.2018.09.011_bib0050","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1600-051X.2006.01002.x","article-title":"Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study","volume":"34","author":"Jones","year":"2007","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.disamonth.2018.09.011_bib0051","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1902\/jop.2009.090206","article-title":"Short-term effects of photodynamic therapy on periodontal status and glycemic control of patients with diabetes","volume":"80","author":"Al-Zahrani","year":"2009","journal-title":"J Periodontol"},{"issue":"3","key":"10.1016\/j.disamonth.2018.09.011_bib0052","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.diabres.2008.10.016","article-title":"Multi-center intervention study on glycohemoglobin (HbA1c) and serum, high-sensitivity CRP (hs-CRP) after local anti-infectious periodontal treatment in type 2 diabetic patients with periodontal disease","volume":"83","author":"Katagiri","year":"2009","journal-title":"Diabetes Res Clin Pract"},{"issue":"2","key":"10.1016\/j.disamonth.2018.09.011_bib0053","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1600-051X.2010.01652.x","article-title":"A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control","volume":"38","author":"Koromantzos","year":"2011","journal-title":"J Clin Periodontol"},{"issue":"4","key":"10.1016\/j.disamonth.2018.09.011_bib0054","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1902\/jop.2011.110327","article-title":"Effects of non-surgical periodontal treatment on clinical response,serum infla mmatory p a rameters, and metabolic control inpatients with type 2 diabetes: a randomized study","volume":"83","author":"Chen","year":"2012","journal-title":"J Periodontol"},{"issue":"23","key":"10.1016\/j.disamonth.2018.09.011_bib0055","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1001\/jama.2013.282431","article-title":"The effect of nonsurgicalperiodontal therapy on hemoglobin A1c levels in personswith type 2 diabetes and chronic periodontitis: arandomized clinical trial","volume":"310","author":"Engebretson S","year":"2013","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.disamonth.2018.09.011_bib0056","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/jcpe.12268","article-title":"The effect of periodontal therapy on glycaemic control in a Hispanic population with type 2 diabetes: a randomized controlled trial","volume":"41","author":"Gay","year":"2014","journal-title":"J Clin Periodontol"},{"issue":"8","key":"10.1016\/j.disamonth.2018.09.011_bib0057","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1601-0825.2012.01943.x","article-title":"Efficacy of short-term adjunctive subantimicrobial dose doxycycline in diabetic patients\u2013randomized study","volume":"18","author":"Gilowski","year":"2012","journal-title":"Oral Dis"},{"issue":"4","key":"10.1016\/j.disamonth.2018.09.011_bib0058","first-page":"1387","article-title":"Effect of topical tetracycline gel with non surgical periodontal therapy on Hba1c and lipid profile in type 2 diabetic patients: a clinico-biochemical study","volume":"22","author":"Haerian Ardakani","year":"2014","journal-title":"J Shahid Sadoughi Univ Med Sci"}],"container-title":["Disease-a-Month"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011502918301305?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011502918301305?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T01:00:56Z","timestamp":1757898056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0011502918301305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":61,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0011502918301305"],"URL":"https:\/\/doi.org\/10.1016\/j.disamonth.2018.09.011","relation":{},"ISSN":["0011-5029"],"issn-type":[{"value":"0011-5029","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of periodontal disease on systemic health","name":"articletitle","label":"Article Title"},{"value":"Disease-a-Month","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.disamonth.2018.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}