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Pediatrics 2018; 148 (3) https:\/\/publications.aap.org\/pediatrics\/article\/142\/3\/e20181889\/38625\/Marijuana-Use-During-Pregnancy-and-Breastfeeding?autologincheck=redirected Last Accessed 09\/24\/24."},{"issue":"2","key":"10.1016\/j.disamonth.2024.101832_bib0076","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1080\/15563650.2019.1661425","article-title":"Synthetic cannabinoid receptor agonists. Classification and nomenclature","volume":"58","author":"Potts","year":"2020","journal-title":"J Clin Toxicol"},{"issue":"5","key":"10.1016\/j.disamonth.2024.101832_bib0077","first-page":"2278","article-title":"Blood cannabinoids. Absorption of THC and formation of 11-OH-THC and THCCOOH during and after smoking marijuana","volume":"16","author":"Heustis","year":"1992","journal-title":"J Anal Toxicol"},{"issue":"4","key":"10.1016\/j.disamonth.2024.101832_bib0078","first-page":"371","article-title":"Metabolism and disposition of delta 0 tetrahydracannabinol in man","volume":"23","author":"Lemberger","year":"1971","journal-title":"Pharmacol Rev"},{"issue":"4","key":"10.1016\/j.disamonth.2024.101832_bib0079","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.pharma.2008.07.006","article-title":"Delta-9 tetrahydracannabinol pharmacokinetics","volume":"66","author":"Goulle","year":"2008","journal-title":"Ann Pharm Fr"},{"issue":"Pt6","key":"10.1016\/j.disamonth.2024.101832_bib0080","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1093\/brain\/awg143","article-title":"Cannabis and the brain","volume":"126","author":"Iversen","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.disamonth.2024.101832_bib0081","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.643315","article-title":"Cannabis use and car crashes: a review","volume":"12","author":"Preuss","year":"2021","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.disamonth.2024.101832_bib0082","unstructured":"Wilsey M., Dees P. Cannabinoid hyperemesis syndrome clinical pathway-johns hopkins all children's hospital 2023 May."},{"issue":"2","key":"10.1016\/j.disamonth.2024.101832_bib0083","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1159\/000494992","article-title":"Cannabinoid hyperemesis","volume":"1","author":"Pergolizzi","year":"2018","journal-title":"Med Cannabis Cannabinoids"},{"key":"10.1016\/j.disamonth.2024.101832_bib0084","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MEG.0000000000001992","article-title":"Endocannabinoid system and cannabis hyperemesis syndrome (CHS): a narrative update. an overview of the endocannabinoid system and its relation to CHS","volume":"34","author":"Perisetti","year":"2022","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.disamonth.2024.101832_bib0085","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/npp.2017.198","article-title":"Hasin DS US epidemiology of cannabis use and associated problems","volume":"43","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.disamonth.2024.101832_bib0086","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1111\/acem.13393","article-title":"Mental health related emergency department visits associated with cannabis in Colorado","volume":"25","author":"Hall","year":"2018","journal-title":"Acad Emer Med"},{"issue":"2","key":"10.1016\/j.disamonth.2024.101832_bib0087","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1053\/j.gastro.2016.04.015","article-title":"The role of the Endocannabinoid system in the brain-gut axis","volume":"141","author":"Sharkey","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.disamonth.2024.101832_bib0088","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1001\/archgenpsychiatry.2008.519","article-title":"Distinct effects of delta 9 tetrahydracannabinol and cannabidiol on neural activation during emotional processing","volume":"66","author":"Fusar-Poli","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.disamonth.2024.101832_bib0089","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1176\/appi.ajp.2017.17030325","article-title":"Cannabidiol (CBD) as an adjunctive therapy in schizophrenia: a multicenter randomized controlled trial","volume":"175","author":"McGuire","year":"2018","journal-title":"Am J Psychiatry"},{"issue":"4","key":"10.1016\/j.disamonth.2024.101832_bib0090","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/MPG.0000000000003220","article-title":"Urinary cannabis metabolite concentrations in cannabis hyperemesis syndrome (CHS)","volume":"73","author":"Cordova","year":"2021","journal-title":"J Pediatr Gastroenterol Nutrition"},{"issue":"7","key":"10.1016\/j.disamonth.2024.101832_bib0091","first-page":"574","article-title":"Improving the diagnosis of cannabinoid hyperemesis syndrome","volume":"111","author":"Burillo Putze","year":"2019","journal-title":"Rev Esp Enferm Dig"},{"key":"10.1016\/j.disamonth.2024.101832_bib0092","unstructured":"ROME Diagnostic criteria-cyclic vomiting syndrome (CVS) and Cannabinoid hyperemesis syndrome (CHS), 2021. https:\/\/theromefoundation.org\/rome-iv\/rome-iv-criteria\/#:\u223c:text=Hyperemesis%20Syndrome%20(CHS)-,Diagnostic%20criteria*%20Must%20include%20all%20of%20the%20following%3A,sustained%20cessation%20of%20cannabis%20use Last accessed 11\/30\/24."},{"key":"10.1016\/j.disamonth.2024.101832_bib0093","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1111\/add.15743","article-title":"Clinical management of cannabis withdrawal","volume":"117","author":"Connor","year":"2022","journal-title":"Addiction"},{"key":"10.1016\/j.disamonth.2024.101832_bib0094","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.drugalcdep.2010.12.010","article-title":"Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial","volume":"116","author":"Levin","year":"2011","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.disamonth.2024.101832_bib0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2020.108366","article-title":"Quetiapine treatment for cannabis use disorder","volume":"218","author":"Mariani","year":"2021","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.disamonth.2024.101832_bib0096","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1001\/jamapsychiatry.2013.3947","article-title":"Nabiximols as an agonist replacement therapy during cannabis withdrawal: a randomized clinical trial","volume":"71","author":"Allsop","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.disamonth.2024.101832_bib0097","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.drugalcdep.2016.02.020","article-title":"Effects of fixed or self-titrated dosages of Sativex on cannabis withdrawal and cravings","volume":"161","author":"Trigo","year":"2016","journal-title":"Drug Alcohol Depend"},{"key":"10.1016\/j.disamonth.2024.101832_bib0098","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1038\/npp.2012.14","article-title":"A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults","volume":"37","author":"Mason","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.disamonth.2024.101832_bib0099","unstructured":"CRAFFT questionnaire https:\/\/njaap.org\/wp-content\/uploads\/2018\/03\/COMBINED-CRAFFT-2.1-Self-Admin_Clinician-Interview_Risk-Assess-Guide.pdf. 2020."},{"key":"10.1016\/j.disamonth.2024.101832_bib0100","unstructured":"HEADSS-the review of systems for adolescents. JAMA J Ethics https:\/\/journalofethics.ama-assn.org\/article\/headss-review-systems-adolescents\/2005-03. 2015. Last Accessed 09\/26\/24."},{"key":"10.1016\/j.disamonth.2024.101832_bib0101","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1111\/add.14234","article-title":"Global statistics on alcohol, tobacco and illicit drug use: 2017 status report","volume":"113","author":"Peacock","year":"2018","journal-title":"Addiction"},{"key":"10.1016\/j.disamonth.2024.101832_bib0102","unstructured":"World Health Organization. International Classification of Diseases for Mortality and Morbidity Statistics (11th Revision) (WHO, version 09\/2020). https:\/\/icd.who.int\/browse11\/l-m\/en."},{"key":"10.1016\/j.disamonth.2024.101832_bib0103","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S2215-0366(18)30337-7","article-title":"The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990\u20132016: a systematic analysis for the Global burden of disease study 2016","volume":"5","author":"Degenhardt","year":"2018","journal-title":"Lancet Psychiatry"},{"key":"10.1016\/j.disamonth.2024.101832_bib0104","doi-asserted-by":"crossref","DOI":"10.1155\/2009\/596149","article-title":"Cannabis and breastfeeding","author":"Garry","year":"2009","journal-title":"J Toxicol"},{"issue":"5","key":"10.1016\/j.disamonth.2024.101832_bib0105","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1097\/AOG.0000000000002575","article-title":"Transfer of inhaled cannabis into human breast mild","volume":"131","author":"Baker","year":"2018","journal-title":"Obstet Gynecol"}],"container-title":["Disease-a-Month"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011502924001585?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0011502924001585?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T17:51:28Z","timestamp":1734025888000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0011502924001585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":105,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0011502924001585"],"URL":"https:\/\/doi.org\/10.1016\/j.disamonth.2024.101832","relation":{},"ISSN":["0011-5029"],"issn-type":[{"value":"0011-5029","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cannabinoid Hyperemesis Syndrome (CHS) - An emerging gastrointestinal disorder and clinical challenge","name":"articletitle","label":"Article Title"},{"value":"Disease-a-Month","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.disamonth.2024.101832","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"101832"}}