{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T11:53:34Z","timestamp":1768737214222,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2006,10,1]],"date-time":"2006-10-01T00:00:00Z","timestamp":1159660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1016\/j.dld.2006.05.025","type":"journal-article","created":{"date-parts":[[2006,9,6]],"date-time":"2006-09-06T14:32:41Z","timestamp":1157553161000},"page":"724-729","source":"Crossref","is-referenced-by-count":38,"title":["Comparison of methylene blue-directed biopsies and four-quadrant biopsies in the detection of high-grade intraepithelial neoplasia and early cancer in Barrett's oesophagus"],"prefix":"10.1016","volume":"38","author":[{"given":"L.","family":"Gossner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Pech","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"May","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Vieth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Stolte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2006.05.025_bib1","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1001\/jama.285.18.2331","article-title":"Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial","volume":"285","author":"Spechler","year":"2001","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.dld.2006.05.025_bib2","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/gast.2000.9302","article-title":"Is there publication bias in the reporting of cancer risk in Barrett's esophagus?","volume":"119","author":"Shaheen","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib3","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0140-6736(05)63269-2","article-title":"Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology?","volume":"350","author":"Prach","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2006.05.025_bib4","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1111\/j.1572-0241.2002.05910.x","article-title":"Updated guidelines for the diagnosis, surveillance and therapy of Barrett's esophagus","volume":"97","author":"Sampliner","year":"2002","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2006.05.025_bib5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1053\/gast.2002.30297","article-title":"Preoperative prevalence of Barrett's esophagus in esophageal adenocarcinoma: a systematic review","volume":"122","author":"Dulai","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib6","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1053\/gast.2002.31879","article-title":"Surveillance and survival in Barrett's adenocarcinomas: a population-based study","volume":"122","author":"Corley","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib7","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/0016-5085(94)90217-8","article-title":"Diagnostic inconsistencies in Barrett's esophagus: Department of Veterans Affairs Gastroesophageal Reflux Study Group","volume":"107","author":"Kim","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib8","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/0016-5085(93)90008-Z","article-title":"An endoscopic biopsy protocol can differentiate high-grade dysplasia from early adenocarcinoma in Barrett's esophagus","volume":"104","author":"Levine","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib9","first-page":"170","article-title":"Jumbo biopsy protocol still misses unsuspected cancer in Barrett's esophagus with high-grade dysplasia","volume":"49","author":"Falk","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib10","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1055\/s-2002-23640","article-title":"Chromoendoscopy of intestinal metaplasia in Barrett's esophagus","volume":"34","author":"Canto","year":"2002","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2006.05.025_bib11","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1067\/mge.2001.115728","article-title":"Methylene blue chromoendoscopy for the detection of patients with short segment\u0301s Barrett's esophagus","volume":"54","author":"Sharma","year":"2001","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib12","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/S0016-5107(00)70290-2","article-title":"Methylene blue-directed biopsies improve detection of intestinal metaplasia and dysplasia in Barrett's esophagus","volume":"51","author":"Canto","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib13","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1067\/mge.2001.115732","article-title":"Comparison of methylene blue-directed biopsies and conventional biopsies in the detection of intestinal metaplasia and dysplasia in Barrett's esophagus: a preliminary study","volume":"54","author":"Wo","year":"2001","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib14","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1136\/gut.52.1.18","article-title":"Biopsy surveillance is still necessary in patients with Barrett's esophagus despite new endoscopic imaging techniques","volume":"52","author":"Egger","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.dld.2006.05.025_bib15","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/S0016-5085(98)70527-X","article-title":"Photodynamic ablation of high-grade dysplasia and early cancer in Barrett's esophagus by means of 5-aminolevulinic acid","volume":"114","author":"Gossner","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib16","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0016-5085(00)70136-3","article-title":"Endoscopic mucosal resection of early cancer and high grade dysplasia in Barrett's esophagus","volume":"118","author":"Ell","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2006.05.025_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1067\/mge.2003.339","article-title":"A prospective randomized trial of two different endoscopic resection techniques for early stage cancer of the esophagus","volume":"58","author":"May","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib18","series-title":"Histological typing of oesophageal and gastric tumours","author":"Watanabe","year":"1990"},{"key":"10.1016\/j.dld.2006.05.025_bib19","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0016-5107(05)00333-0","article-title":"Long-term results of photodynamic therapy with 5-aminolevulinic acid for superficial Barrett's cancer and high-grade intraepithelial neoplasia","volume":"62","author":"Pech","year":"2005","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0016-5107(96)70221-3","article-title":"Methylene blue selectively stains intestinal metaplasia in Barrett's esophagus","volume":"44","author":"Canto","year":"1996","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib21","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1067\/mge.2001.111041","article-title":"Screening for specialized columnar epithelium with methylene blue: chromoendoscopy for patients with Barrett's esophagus and a normal control group","volume":"53","author":"Kiesslich","year":"2001","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib22","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1067\/mge.2003.137","article-title":"Does methylene blue detect intestinal metaplasia in Barrett's esophagus?","volume":"57","author":"Breyer","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib23","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1055\/s-2003-38768","article-title":"Methylene blue chromoendoscopy for the detection of Barrett's esophagus","volume":"35","author":"Kouklakis","year":"2003","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2006.05.025_bib24","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1055\/s-2003-44599","article-title":"A randomized, prospective cross-over trial comparing methylene blue-directed biopsy and conventional random biopsy for detecting intestinal metaplasia and dysplasia in Barrett's esophagus","volume":"35","author":"Ragunath","year":"2003","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2006.05.025_bib25","first-page":"AB54","article-title":"Results of methylene blue-directed biopsy is similar to concentional biopsy for the diagnosis of intestinal metaplasia and dysplasia in Barrett's esophagus","volume":"49","author":"Mukunda","year":"1999","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib26","first-page":"333","article-title":"Methylene blue staining: is it really useful in Barrett's esophagus?","volume":"53","author":"Dave","year":"2001","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2006.05.025_bib27","first-page":"407","article-title":"Prospective long-term endoscopic and histological follow-up of short segment Barrett's esophagus: comparison with traditional long segment Barrett's esophagus","volume":"92","author":"Weston","year":"1997","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2006.05.025_bib28","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0140-6736(03)14026-3","article-title":"Chromoendoscopy with methylene blue and associated DNA damage in Barrett's esophagus","volume":"362","author":"Olliver","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2006.05.025_bib29","series-title":"DNA repair and mutagenesis","author":"Friedberg","year":"1995"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865806002386?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865806002386?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,13]],"date-time":"2019-01-13T14:59:09Z","timestamp":1547391549000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865806002386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10]]}},"alternative-id":["S1590865806002386"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2006.05.025","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2006,10]]}}}