{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:33:33Z","timestamp":1790177613594,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1016\/j.dld.2008.06.008","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T16:51:24Z","timestamp":1217263884000},"page":"245-252","source":"Crossref","is-referenced-by-count":27,"title":["Microscopic enteritis: Novel prospect in coeliac disease clinical and immuno-histogenesis. Evolution in diagnostic and treatment strategies"],"prefix":"10.1016","volume":"41","author":[{"given":"K.","family":"Rostami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Villanacci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2008.06.008_bib1","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/S1590-8658(03)00460-2","article-title":"From microenteropathy to villous atrophy: what is treatable?","volume":"35","author":"Rostami","year":"2003","journal-title":"Dig Liver Dis"},{"issue":"Suppl.","key":"10.1016\/j.dld.2008.06.008_bib2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1679\/aohc.55.Suppl_125","article-title":"Scanning electron microscopy of the small intestine during gluten-challenge in celiac disease","volume":"55","author":"Magliocca","year":"1992","journal-title":"Arch Histol Cytol"},{"key":"10.1016\/j.dld.2008.06.008_bib3","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/S1590-8658(03)00457-2","article-title":"Gluten sensitivity and \u2018normal\u2019 histology: is the intestinal mucosa really normal?","volume":"35","author":"Sbarbati","year":"2003","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2008.06.008_bib4","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1097\/00042737-199904000-00013","article-title":"The relationship between anti-endomysium antibodies and villous atrophy in coeliac disease using both monkey and human substrate","volume":"11","author":"Rostami","year":"1999","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2008.06.008_bib5","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1111\/j.1572-0241.2001.03947.x","article-title":"Disappointing sensitivity of endoscopic markers for villous atrophy in a high-risk population: implications for celiac disease diagnosis during routine endoscopy","volume":"96","author":"Dickey","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib6","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1111\/j.1572-0241.2001.03744.x","article-title":"Low prevalence of antigliadin and anti-endomysium antibodies in subclinical\/silent celiac disease","volume":"96","author":"Tursi","year":"2001","journal-title":"Am J Gastroenterol"},{"issue":"Suppl.","key":"10.1016\/j.dld.2008.06.008_bib7","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1651-2227.1996.tb14240.x","article-title":"Latent and potential coeliac disease","volume":"412","author":"Troncone","year":"1996","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.dld.2008.06.008_bib8","doi-asserted-by":"crossref","first-page":"595","DOI":"10.3109\/00365529309096094","article-title":"Follow-up of patients positive in reticulin and gliadin antibody tests with normal small-bowel biopsy findings","volume":"28","author":"Collin","year":"1993","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib9","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1136\/gut.32.11.1412","article-title":"Increase in gamma\/delta T cell receptor bearing lymphocytes in normal small bowel mucosa in latent coeliac disease","volume":"32","author":"Maki","year":"1991","journal-title":"Gut"},{"key":"10.1016\/j.dld.2008.06.008_bib10","doi-asserted-by":"crossref","first-page":"2294","DOI":"10.1111\/j.1572-0241.2005.41134.x","article-title":"Clinical, HLA, and small bowel immuno-histochemical features of children with positive serum antiendomysium antibodies and architecturally normal small intestinal mucosa","volume":"100","author":"Paparo","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib11","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1053\/gast.2002.35381","article-title":"Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues","volume":"123","author":"Arentz-Hansen","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2008.06.008_bib12","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1365-2036.2006.02997.x","article-title":"Immunoglobulin A autoantibodies against transglutaminase 2 in the small intestinal mucosa predict forthcoming coeliac disease","volume":"24","author":"Salmi","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2008.06.008_bib13","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1053\/j.gastro.2006.10.004","article-title":"American gastroenterological association (AGA) institute technical review on the diagnosis and management of celiac disease","volume":"131","author":"Rostom","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2008.06.008_bib14","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/00042737-199601000-00005","article-title":"Serological markers identify histologically latent coeliac disease among first-degree relatives","volume":"8","author":"Vazquez","year":"1996","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2008.06.008_bib15","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1136\/jcp.2005.035345","article-title":"Coeliac disease: an update for pathologists","volume":"59","author":"Dickson","year":"2006","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.dld.2008.06.008_bib16","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0046-8177(75)80176-6","article-title":"Symposium on pathology of the gastrointestinal tract-Part II. Small intestinal biopsy","volume":"6","author":"Perera","year":"1975","journal-title":"Hum Pathol"},{"key":"10.1016\/j.dld.2008.06.008_bib17","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1373\/clinchem.2005.061366","article-title":"Anti-transglutaminase antibody assay of the culture medium of intestinal biopsy specimens can improve the accuracy of celiac disease diagnosis","volume":"52","author":"Carroccio","year":"2006","journal-title":"Clin Chem"},{"key":"10.1016\/j.dld.2008.06.008_bib18","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/0016-5085(92)91819-P","article-title":"Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity (\u2018celiac sprue\u2019)","volume":"102","author":"Marsh","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2008.06.008_bib19","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0140-6736(81)92860-9","article-title":"Gluten-induced mucosal changes in subjects without overt small-bowel disease","volume":"1","author":"Doherty","year":"1981","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2008.06.008_bib20","first-page":"113","article-title":"A quantitative assessment of jejunal villous damage in coeliac disease, using the mucosal index","volume":"30","author":"Challacombe","year":"1983","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.dld.2008.06.008_bib21","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1136\/gut.34.12.1740","article-title":"Clinical and pathological spectrum of coeliac disease","volume":"34","author":"Marsh","year":"1993","journal-title":"Gut"},{"key":"10.1016\/j.dld.2008.06.008_bib22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0300-2977(98)00050-3","article-title":"SAT and serology in adult coeliacs, seronegative coeliac disease seems a reality","volume":"53","author":"Rostami","year":"1998","journal-title":"Neth J Med"},{"key":"10.1016\/j.dld.2008.06.008_bib23","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1309\/EVXT-851X-WHLC-RLX9","article-title":"Histologic follow-up of people with celiac disease on a gluten-free diet: slow and incomplete recovery","volume":"118","author":"Wahab","year":"2002","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.dld.2008.06.008_bib24","first-page":"109","article-title":"Expression of cell adhesion molecules in jejunum biopsies of children with coeliac disease","volume":"25","author":"Villanacci","year":"1993","journal-title":"Ital J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib25","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.cgh.2007.03.019","article-title":"Comparison of the interobserver reproducibility with different histologic criteria used in celiac disease","volume":"5","author":"Corazza","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2008.06.008_bib26","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1136\/jcp.55.5.393","article-title":"Quantitation of intraepithelial lymphocytes in human duodenum: what is normal?","volume":"55","author":"Hayat","year":"2002","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.dld.2008.06.008_bib27","first-page":"101","article-title":"Autoantibodies and histogenesis of celiac disease","volume":"12","author":"Rostami","year":"2003","journal-title":"Rom J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib28","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1111\/j.1572-0241.1999.983_f.x","article-title":"Sensitivity of antiendomysium and antigliadin antibodies in untreated celiac disease: disappointing in clinical practice","volume":"94","author":"Rostami","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib29","unstructured":"Meijer J. Histological aspect of CD and its complications. PhD thesis, Amsterdam; 2006."},{"key":"10.1016\/j.dld.2008.06.008_bib30","first-page":"67","article-title":"Role of magnification endoscopy in the diagnosis and evaluation of suspected celiac disease: correlation with histology","volume":"26","author":"Banerjee","year":"2007","journal-title":"Indian J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib31","doi-asserted-by":"crossref","unstructured":"When is a coeliac a coeliac? Report of a working group of the United European gastroenterology week in Amsterdam, 2001. Eur J Gastroenterol Hepatol 2001;13(9):1123\u20138.","DOI":"10.1097\/00042737-200109000-00023"},{"key":"10.1016\/j.dld.2008.06.008_bib32","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.bpg.2005.02.006","article-title":"Diagnosis of coeliac disease","volume":"19","author":"Green","year":"2005","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib33","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.cgh.2007.10.012","article-title":"Mucosal atrophy in celiac disease: extent of involvement, correlation with clinical presentation, and response to treatment","volume":"6","author":"Murray","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2008.06.008_bib34","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/ncpgasthep0877","article-title":"Does clinical presentation correlate with degree of villous atrophy in patients with celiac disease?","volume":"4","author":"Ciclitira","year":"2007","journal-title":"Nat Clin Pract Gastroenterol Hepatol"},{"issue":"Suppl.","key":"10.1016\/j.dld.2008.06.008_bib35","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1651-2227.1992.tb12375.x","article-title":"Small intestinal mucosal histology in the syndrome of persistent diarrhoea and malnutrition: a review","volume":"381","author":"Sullivan","year":"1992","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.dld.2008.06.008_bib36","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1136\/gut.33.2.206","article-title":"Increase of lymphocytes bearing the gamma\/delta T cell receptor in the jejunum of patients with dermatitis herpetiformis","volume":"33","author":"Savilahti","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.dld.2008.06.008_bib37","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1111\/j.1572-0241.2007.01173.x","article-title":"Detection of Celiac disease in primary care: a multicenter case-finding study in North America","volume":"102","author":"Catassi","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib38","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1111\/j.1572-0241.2007.01167.x","article-title":"Where are all those patients with Celiac disease?","volume":"102","author":"Green","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib39","doi-asserted-by":"crossref","unstructured":"Catassi C, Kryszak D, Louis-Jacques O, Duerksen DR, Hill I, Crowe SE, et al. Detection of Celiac Disease in Primary Care: A Multicenter Case-Finding Study in North America. Am J Gastroenterol 2007.","DOI":"10.1111\/j.1572-0241.2007.01173.x"},{"key":"10.1016\/j.dld.2008.06.008_bib40","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1572-0241.2005.40669.x","article-title":"Variability of histologic lesions in relation to biopsy site in gluten-sensitive enteropathy","volume":"100","author":"Ravelli","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib41","first-page":"54","article-title":"Celiac disease: epidemiology, pathogenesis, diagnosis, and nutritional management","volume":"8","author":"Schuppan","year":"2005","journal-title":"Nutr Clin Care"},{"key":"10.1016\/j.dld.2008.06.008_bib42","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1093\/ajcn\/86.1.260","article-title":"Safe gluten threshold for patients with celiac disease: some patients are more tolerant than others","volume":"86","author":"Collin","year":"2007","journal-title":"Am J Clin Nutr"},{"issue":"4","key":"10.1016\/j.dld.2008.06.008_bib43","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/00004836-200204000-00009","article-title":"Celiac disease in Brazilian adults","volume":"34","author":"de Freitas","year":"2002","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib44","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1136\/gut.2006.100511","article-title":"Long-term follow-up of 61 coeliac patients diagnosed in childhood: evolution toward latency is possible on a normal diet","volume":"56","author":"Matysiak-Budnik","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.dld.2008.06.008_bib45","first-page":"142","article-title":"Advances in celiac disease","volume":"23","author":"Craig","year":"2007","journal-title":"Curr Opin Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib46","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/01.sla.0000171301.35513.cf","article-title":"Association of adult celiac disease with surgical abdominal pain: a case-control study in patients referred to secondary care","volume":"242","author":"Sanders","year":"2005","journal-title":"Ann Surg"},{"key":"10.1016\/j.dld.2008.06.008_bib47","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1046\/j.1365-2036.2003.01666.x","article-title":"Coeliac disease presenting with symptoms of irritable bowel syndrome","volume":"18","author":"Shahbazkhani","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2008.06.008_bib48","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.dld.2006.06.041","article-title":"Diagnosis underlying appendectomy and coeliac disease risk","volume":"38","author":"Ludvigsson","year":"2006","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2008.06.008_bib49","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/00004836-200301000-00006","article-title":"The symptomatic and histologic response to a gluten-free diet in patients with borderline enteropathy","volume":"36","author":"Tursi","year":"2003","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib50","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S1590-8658(02)80190-6","article-title":"Endoscopic markers in adult coeliac disease","volume":"34","author":"Brocchi","year":"2002","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2008.06.008_bib51","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.dld.2006.07.005","article-title":"Histological aspects of the terminal ileum: a windows on coeliac disease too?","volume":"38","author":"Villanacci","year":"2006","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2008.06.008_bib52","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s00428-002-0709-7","article-title":"Small intestinal biopsies in celiac disease: duodenal or jejunal?","volume":"442","author":"Meijer","year":"2003","journal-title":"Virchows Arch"},{"key":"10.1016\/j.dld.2008.06.008_bib53","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1136\/jcp.55.6.424","article-title":"Is a raised intraepithelial lymphocyte count with normal duodenal villous architecture clinically relevant?","volume":"55","author":"Mahadeva","year":"2002","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.dld.2008.06.008_bib54","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1111\/j.1572-0241.2001.03812.x","article-title":"Gluten challenge in borderline gluten-sensitive enteropathy","volume":"96","author":"Wahab","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib55","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/01.mcg.0000212616.66713.61","article-title":"Is TCRgamma clonality assay useful to detect early celiac disease?","volume":"41","author":"Ubiali","year":"2007","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib56","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1111\/j.1572-0241.2006.00621.x","article-title":"Helicobacter pylori infection in patients with celiac disease","volume":"101","author":"Villanacci","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2008.06.008_bib57","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.1365-2036.2008.03652.x","article-title":"Diagnostic value of duodenal antitissue transglutaminase antibodies in gluten-sensitive enteropathy","volume":"27","author":"Santaolalla","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2008.06.008_bib58","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.dld.2006.07.014","article-title":"Lack of correlation of degree of villous atrophy with severity of clinical presentation of coeliac disease","volume":"39","author":"Brar","year":"2007","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2008.06.008_bib59","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1023\/A:1010729207320","article-title":"Celiac disease without villous atrophy: revision of criteria called for","volume":"46","author":"Kaukinen","year":"2001","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2008.06.008_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.dld.2008.03.013","article-title":"Undetected coeliac disease in the elderly A biopsy-proven population-based study","author":"Vilppula","year":"2008","journal-title":"Dig Liver Dis"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865808002521?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865808002521?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T08:40:24Z","timestamp":1588840824000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865808002521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["S1590865808002521"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2008.06.008","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2009,4]]}}}