{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T20:11:22Z","timestamp":1792613482760,"version":"4.5.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.dld.2011.08.029","type":"journal-article","created":{"date-parts":[[2011,10,11]],"date-time":"2011-10-11T09:45:45Z","timestamp":1318326345000},"page":"166-171","source":"Crossref","is-referenced-by-count":162,"title":["Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure"],"prefix":"10.1016","volume":"44","author":[{"given":"Hitendra","family":"Garg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveen","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barjesh Chander","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiv Kumar","family":"Sarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2011.08.029_bib0005","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1159\/000047017","article-title":"Acute-on-chronic liver failure: pathophysiological basis of therapeutic options","volume":"20","author":"Jalan","year":"2002","journal-title":"Blood Purif"},{"key":"10.1016\/j.dld.2011.08.029_bib0010","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0016-5085(89)90081-4","article-title":"Early indicators of prognosis in fulminant hepatic failure","volume":"97","author":"O\u2019Grady","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2011.08.029_bib0015","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s12072-008-9106-x","article-title":"Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)","volume":"3","author":"Sarin","year":"2009","journal-title":"Hepatol Int"},{"key":"10.1016\/j.dld.2011.08.029_bib0020","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1007\/s00134-007-0760-6","article-title":"RIFLE classification can predict short-term prognosis in critically ill cirrhotic patients","volume":"33","author":"Jenq","year":"2007","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.dld.2011.08.029_bib0025","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1002\/lt.20236","article-title":"Pathophysiological effects of albumin dialysis in acute-on-chronic liver failure: a randomized controlled study","volume":"10","author":"Sen","year":"2004","journal-title":"Liver Transpl"},{"key":"10.1016\/j.dld.2011.08.029_bib0030","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1053\/jhep.2001.26522","article-title":"Short-term prognosis in critically ill patients with cirrhosis assessed by prognostic scoring systems","volume":"34","author":"Wehler","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.08.029_bib0035","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1111\/j.1365-2036.2006.02842.x","article-title":"Risk factors, sequential organ failure assessment and model for end-stage liver disease scores for predicting short term mortality in cirrhotic patients admitted to intensive care unit","volume":"23","author":"Cholongitas","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2011.08.029_bib0040","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1097\/00003246-199811000-00016","article-title":"Use of the SOFA score to assess the incidence of organ dysfunction\/failure in intensive care units: results of a multicenter, prospective study. Working group on \u201csepsis-related problems\u201d of the European Society of Intensive Care Medicine","volume":"26","author":"Vincent","year":"1998","journal-title":"Crit Care Med"},{"key":"10.1016\/j.dld.2011.08.029_bib0045","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000078789","article-title":"Multiple organ system failure in critically ill cirrhotic patients. A comparison of two multiple organ dysfunction\/failure scoring systems","volume":"69","author":"Tsai","year":"2004","journal-title":"Digestion"},{"key":"10.1016\/j.dld.2011.08.029_bib0050","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1097\/00042737-200012050-00007","article-title":"Short-term prognosis in critically ill patients with liver cirrhosis: an evaluation of a new scoring system","volume":"12","author":"Zauner","year":"2000","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2011.08.029_bib0055","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/BF01708096","article-title":"Outcome prediction for patients with cirrhosis of the liver in a medical ICU: a comparison of the APACHE scores and liver-specific scoringsystems","volume":"22","author":"Zauner","year":"1996","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.dld.2011.08.029_bib0060","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1007\/s00134-004-2346-x","article-title":"Does intubation really equal death in cirrhotic patients? Factors influencing outcome in patients with liver cirrhosis requiring mechanical ventilation","volume":"30","author":"Rabe","year":"2004","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.dld.2011.08.029_bib0065","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1378\/chest.119.5.1489","article-title":"Predictors of mortality and resource utilization in cirrhotic patients admitted to the medical ICU","volume":"119","author":"Aggarwal","year":"2001","journal-title":"Chest"},{"key":"10.1016\/j.dld.2011.08.029_bib0070","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1378\/chest.126.5.1598","article-title":"Predictors of long-term mortality in patients with cirrhosis of the liver admitted to a medical ICU","volume":"126","author":"Gildea","year":"2004","journal-title":"Chest"},{"key":"10.1016\/j.dld.2011.08.029_bib0075","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s005350050047","article-title":"Outcome of patients with cirrhosis requiring intensive care unit support: prospective assessment of predictors of mortality","volume":"33","author":"Singh","year":"1998","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.dld.2011.08.029_bib0080","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1053\/jhep.2002.36130","article-title":"Albumin dialysis in cirrhosis with superimposed acute liver injury: a prospective, controlled study","volume":"36","author":"Heemann","year":"2002","journal-title":"Hepatology"},{"issue":"Suppl. 1","key":"10.1016\/j.dld.2011.08.029_bib0085","first-page":"489A","article-title":"Baseline SOFA score and its lack of early improvement accurately predicts mortality in patients with acute-on-chronic liver failure","volume":"40","author":"Sen","year":"2004","journal-title":"Hepatology"},{"issue":"Suppl. 2","key":"10.1016\/j.dld.2011.08.029_bib0090","doi-asserted-by":"crossref","first-page":"S69","DOI":"10.1016\/S0168-8278(06)80166-2","article-title":"Evaluation of four prognostic scores in patients with acute-on-chronic liver failure","volume":"44","author":"Stauber","year":"2006","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.08.029_bib0095","first-page":"607","article-title":"Analysis of prognostic factors for patients with acute-on-chronic liver failure","volume":"17","author":"Liu","year":"2009","journal-title":"Zhonghua Gan Zang Bing Za Zhi"},{"key":"10.1016\/j.dld.2011.08.029_bib0100","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1111\/j.1440-1746.2006.04510.x","article-title":"Prediction of the prognosis in patients with acute-on-chronic hepatitis using the MELD scoring system","volume":"21","author":"Yu","year":"2006","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2011.08.029_bib0105","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/00004836-200309000-00011","article-title":"Organ system failure scoring system can predict hospital mortality in critically ill cirrhotic patients","volume":"37","author":"Tsai","year":"2003","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2011.08.029_bib0110","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1177\/0885066603261991","article-title":"Outcome prediction for critically ill cirrhotic patients: a comparison of APACHE II and Child\u2013Pugh scoring systems","volume":"19","author":"Ho","year":"2004","journal-title":"J Intensive Care Med"},{"key":"10.1016\/j.dld.2011.08.029_bib0115","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.jhep.2005.02.002","article-title":"MELD is not enough\u2013enough of MELD?","volume":"42","author":"Cholongitas","year":"2005","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.08.029_bib0120","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.3748\/wjg.v11.i20.3099","article-title":"MELD vs Child\u2013Pugh and creatinine-modified Child\u2013Pugh score for predicting survival in patients with decompensated cirrhosis","volume":"11","author":"Papatheodoridis","year":"2005","journal-title":"World J Gastroenterol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865811003409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865811003409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,29]],"date-time":"2018-11-29T16:22:49Z","timestamp":1543508569000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865811003409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S1590865811003409"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2011.08.029","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}