{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:18:02Z","timestamp":1791001082906,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.dld.2011.12.016","type":"journal-article","created":{"date-parts":[[2012,2,9]],"date-time":"2012-02-09T13:45:19Z","timestamp":1328795119000},"page":"504-507","source":"Crossref","is-referenced-by-count":19,"title":["Platelet count\/spleen diameter ratio for non-invasive diagnosis of oesophageal varices: Is it useful in compensated cirrhosis?"],"prefix":"10.1016","volume":"44","author":[{"given":"Manuela","family":"Mangone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Moretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Alivernini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Papi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruggero","family":"Orefice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Dezi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuela","family":"Amadei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Aratari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Tornatore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Koch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2011.12.016_bib0005","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/jhep.2001.21410","article-title":"Which patients should undergo endoscopic screening for oesophageal varices detection?","volume":"33","author":"Schepis","year":"2001","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0010","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0950-3528(97)90038-5","article-title":"Natural history. Clinical-haemodynamic correlations. Prediction of the risk of bleeding","volume":"11","author":"D\u2019Amico","year":"1997","journal-title":"Baillieres Clin Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0015","doi-asserted-by":"crossref","first-page":"38","DOI":"10.4103\/1319-3767.58767","article-title":"Noninvasive prediction of large esophageal varices in chronic liver disease patients","volume":"16","author":"Sarangapani","year":"2010","journal-title":"Saudi J Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0020","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jhep.2010.06.004","article-title":"Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension","volume":"53","author":"De Franchis","year":"2010","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0025","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S1590-8658(03)00219-6","article-title":"Non-invasive predictors of the presence of large oesophageal varices in patients with cirrhosis","volume":"35","author":"Thomopoulos","year":"2003","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2011.12.016_bib0030","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1111\/j.1572-0241.2008.01826.x","article-title":"Noninvasive prediction of clinically significant portal hypertension and esophageal varices in patients with compensated liver cirrhosis","volume":"103","author":"Berzigotti","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0035","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/hep.20029","article-title":"Prevalence and predictors of oesophageal varices in patients with primary sclerosing cholangitis","volume":"39","author":"Zein","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0040","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S0168-8278(99)80288-8","article-title":"Non-invasive diagnosis of esophageal varices in chronic liver disease","volume":"31","author":"Pilette","year":"1999","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0045","doi-asserted-by":"crossref","first-page":"2564","DOI":"10.1001\/archinte.161.21.2564","article-title":"Risk factors for the presence of varices in cirrhotic patients without history of variceal hemorrhage","volume":"161","author":"Zaman","year":"2001","journal-title":"Arch Int Med"},{"key":"10.1016\/j.dld.2011.12.016_bib0050","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1111\/j.1440-1746.2006.04501.x","article-title":"Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parameters","volume":"22","author":"Sharma","year":"2007","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0055","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1046\/j.1440-1746.1999.01949.x","article-title":"Prediction of oesophagogastric varices in patients with liver cirrhosis","volume":"14","author":"Ng","year":"1999","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0060","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/01.mcg.0000225669.84099.04","article-title":"Validation of a multivariate model predicting presence and size of varices","volume":"41","author":"Burton","year":"2007","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0065","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1478-3231.2005.01227.x","article-title":"Non-invasive diagnosis of large oesophageal varices with FibroTest in patients with cirrhosis: a preliminary retrospective study","volume":"26","author":"Thabut","year":"2006","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2011.12.016_bib0070","doi-asserted-by":"crossref","first-page":"189","DOI":"10.7863\/jum.1986.5.4.189","article-title":"Predictive value of ultrasonography in the screening of non-ascitic cirrhotic patients with large varices","volume":"5","author":"Cottone","year":"1986","journal-title":"J Ultrasound Med"},{"key":"10.1016\/j.dld.2011.12.016_bib0075","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/00004836-200201000-00016","article-title":"Prediction of oesophageal varices in patients with cirrhosis","volume":"34","author":"Madhotra","year":"2002","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0080","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1136\/gut.52.8.1200","article-title":"Platelet count\/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis","volume":"52","author":"Giannini","year":"2003","journal-title":"Gut"},{"key":"10.1016\/j.dld.2011.12.016_bib0085","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.dld.2005.05.007","article-title":"Application of the platelet count\/spleen diameter ratio to rule out the presence of oesophageal varices in patients with cirrhosis: a validation study based on follow up","volume":"37","author":"Giannini","year":"2005","journal-title":"Dig Liv Dis"},{"key":"10.1016\/j.dld.2011.12.016_bib0090","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1111\/j.1572-0241.2006.00874.x","article-title":"Platelet count\/spleen diameter ratio for the noninvasive diagnosis of esophageal varices: results of a multicenter, prospective, validation study","volume":"101","author":"Giannini","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0095","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.jhep.2006.04.006","article-title":"Liver stiffness measurement selects patients with cirrhosis at risk of bearing large oesophageal varices","volume":"45","author":"Kazemi","year":"2006","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0100","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1002\/hep.21665","article-title":"Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosis","volume":"45","author":"Vizzutti","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0105","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1002\/hep.22219","article-title":"A prospective evaluation of computerized tomographic (CT) scanning as a screening modality for esophageal varices","volume":"47","author":"Perri","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0110","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2214\/AJR.05.1737","article-title":"Oesophageal varices in cirrhotic patients: evaluation with liver CT","volume":"188","author":"Kim","year":"2007","journal-title":"AJR"},{"key":"10.1016\/j.dld.2011.12.016_bib0115","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1148\/radiol.2423050784","article-title":"Oesophageal varices in patients with cirrhosis: multidetector CT esophagography\u2014comparison with endoscopy","volume":"242","author":"Kim","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.dld.2011.12.016_bib0120","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.dld.2007.10.022","article-title":"Study comparing oesophageal capsule endoscopy versus EGD in the detection of varices","volume":"40","author":"Pena","year":"2008","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2011.12.016_bib0125","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1002\/hep.22227","article-title":"Oesophageal capsule endoscopy for screening and surveillance of oesophageal varices in patients with portal hypertension","volume":"47","author":"De Franchis","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0130","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1055\/s-2005-921189","article-title":"The accuracy of PillCam ESO capsule endoscopy versus conventional upper endoscopy for the diagnosis of oesophageal varices: a prospective three-center pilot study","volume":"38","author":"Eisen","year":"2006","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2011.12.016_bib0135","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1055\/s-2006-924975","article-title":"Esophageal capsule endoscopy versus esophagogastroduodenoscopy for evaluating portal hypertension: a prospective comparative study of performance and tolerance","volume":"38","author":"Lapalus","year":"2006","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2011.12.016_bib0140","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1097\/MCG.0b013e3181a745ff","article-title":"Utilization of platelet count spleen diameter ratio in predicting the presence of esophageal varices in patients with cirrhosis","volume":"44","author":"Schwarzenberger","year":"2010","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0145","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/s10620-008-0367-y","article-title":"External validation of the platelet count\/spleen diameter ratio for the diagnosis of esophageal varices in hepatitis C virus-related cirrhosis","volume":"54","author":"Agha","year":"2009","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2011.12.016_bib0150","doi-asserted-by":"crossref","first-page":"2454","DOI":"10.3748\/wjg.14.2454","article-title":"Non-invasive prediction of oesophageal varices in cirrhosis","volume":"14","author":"Sen","year":"2008","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0155","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1155\/2008\/287274","article-title":"Platelet count to spleen diameter ratio for the diagnosis of esophageal varices. Is it feasible?","volume":"22","author":"Baig","year":"2008","journal-title":"Can J Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0160","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S1665-2681(19)31745-4","article-title":"Platelet count\/spleen diameter ratio for non-invasive prediction of high risk esophageal varices in cirrhotic patients","volume":"8","author":"Barrera","year":"2009","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0165","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-230X-9-11","article-title":"Predictors of esophageal varices in patients with HBV-related cirrhosis: a retrospective study","volume":"9","author":"Hong","year":"2009","journal-title":"BMC Gastroenterol"},{"key":"10.1016\/j.dld.2011.12.016_bib0170","first-page":"1","article-title":"Prediction severity of esophageal varices: a new cut-off point for platelet count\/spleen diameter ratio","volume":"56","author":"Barikbin","year":"2010","journal-title":"Minerva Gastro Dietol"},{"key":"10.1016\/j.dld.2011.12.016_bib0175","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/S1665-2681(19)31643-6","article-title":"Platelet count\/spleen diameter ratio as a predictor of esophageal varices in cirrhotic patients","volume":"9","author":"Zambam de Mattos","year":"2010","journal-title":"Ann Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0180","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1053\/jhep.2003.50346","article-title":"A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C","volume":"38","author":"Wai","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0185","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0168-8278(97)80140-7","article-title":"What is the criterion for differentiating chronic hepatitis from compensated cirrhosis? A prospective study comparing ultrasonography and percutaneous liver biopsy","volume":"27","author":"Gaiani","year":"1997","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0190","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/S0168-8278(99)80107-X","article-title":"Ultrasonographic diagnosis of hepatic fibrosis or cirrhosis","volume":"30","author":"Aub\u00e8","year":"1999","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0195","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/hep.1840010511","article-title":"Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis","volume":"1","author":"Knodell","year":"1981","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0200","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/0168-8278(95)80226-6","article-title":"Histological grading and staging of chronic hepatitis","volume":"22","author":"Ishak","year":"1995","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0205","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/0168-8278(91)90084-O","article-title":"Classification of chronic viral hepatitis: a need for reassessment","volume":"13","author":"Scheuer","year":"1991","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2011.12.016_bib0210","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/hep.510240201","article-title":"An algorithm for the grading of activity in chronic hepatitis C","volume":"24","author":"Bedossa","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2011.12.016_bib0215","first-page":"983","article-title":"The North Italian Endoscopic Club for the study and treatment of esophageal varices","volume":"319","author":"De Franchis","year":"1988","journal-title":"N Engl J Med"},{"key":"10.1016\/j.dld.2011.12.016_bib0220","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1136\/gut.26.11.1226","article-title":"Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy","volume":"26","author":"McCormack","year":"1985","journal-title":"Gut"},{"key":"10.1016\/j.dld.2011.12.016_bib0225","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1590\/S0004-28032010000300012","article-title":"Platelet count\/spleen diameter ratio: analysis of its capacity as a predictor of the existence of esophageal varices","volume":"47","author":"Mattos","year":"2010","journal-title":"Arq Gastroenterol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865811005007?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865811005007?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:30:51Z","timestamp":1593649851000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865811005007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S1590865811005007"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2011.12.016","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}