{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:14:34Z","timestamp":1761743674736},"reference-count":32,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.dld.2012.08.002","type":"journal-article","created":{"date-parts":[[2012,9,4]],"date-time":"2012-09-04T01:00:20Z","timestamp":1346720420000},"page":"988-994","source":"Crossref","is-referenced-by-count":11,"title":["Donor-derived bone marrow transfusion produces mixed chimerism and promotes a Th2 shift in Th1\/Th2 balance in rat heterotopic small bowel transplantation"],"prefix":"10.1016","volume":"44","author":[{"given":"Anbin","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huijuan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Tai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linwei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bimang","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoshun","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2012.08.002_bib0005","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1056\/NEJMra0804605","article-title":"Intestinal transplantation","volume":"361","author":"Fishbein","year":"2009","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.dld.2012.08.002_bib0010","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1111\/j.1600-6135.2005.00839.x","article-title":"Goodrich, liver and intestine transplantation: summary analysis, 1994\u20132003","volume":"5","author":"Hanto","year":"2005","journal-title":"American Journal of Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0015","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1097\/01.TP.0000083042.03188.6C","article-title":"Isolated intestinal transplantation: proof of clinical efficacy","volume":"76","author":"Fishbein","year":"2003","journal-title":"Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0020","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1097\/MOT.0b013e32834ee68b","article-title":"Mixed chimerism through donor bone marrow transplantation: a tolerogenic cell therapy for application in organ transplantation","volume":"17","author":"Pilat","year":"2012","journal-title":"Current Opinion in Organ Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0025","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nrneph.2010.110","article-title":"Transplantation tolerance through mixed chimerism","volume":"6","author":"Pilat","year":"2010","journal-title":"Nature Reviews Nephrology"},{"key":"10.1016\/j.dld.2012.08.002_bib0030","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1002\/hep.1840170629","article-title":"Cell migration and chimerism after whole-organ transplantation: the basis of graft acceptance","volume":"17","author":"Starzl","year":"1993","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2012.08.002_bib0035","first-page":"87","article-title":"Long survival in rats after multivisceral versus isolated small-bowel allotransplantation under FK 506","volume":"110","author":"Murase","year":"1991","journal-title":"Surgery"},{"key":"10.1016\/j.dld.2012.08.002_bib0040","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.trim.2004.06.006","article-title":"The impact of portal infusion with donor-derived bone marrow cells and intracellular cytokine expression of graft-infiltrating lymphocytes on the graft survival in rat small bowel transplant model","volume":"13","author":"Mitsuoka","year":"2004","journal-title":"Transplant Immunology"},{"key":"10.1016\/j.dld.2012.08.002_bib0045","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1016\/S0041-1345(00)01230-6","article-title":"Donor-specific portal transfusion augments microchimerism in a porcine model of small bowel transplantation","volume":"32","author":"Morin","year":"2000","journal-title":"Transplantation Proceedings"},{"key":"10.1016\/j.dld.2012.08.002_bib0050","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1034\/j.1399-3046.1999.00010.x","article-title":"Correlation between allograft survival and chimeric state after bone marrow infusion in rat small bowel transplantation","volume":"3","author":"Bakonyi","year":"1999","journal-title":"Pediatric Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0055","first-page":"693","article-title":"Transplantation of small bowel in the rat: technical and immunological considerations","volume":"70","author":"Monchik","year":"1971","journal-title":"Surgery"},{"key":"10.1016\/j.dld.2012.08.002_bib0060","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1365-2249.1993.tb03432.x","article-title":"Comparison of potentiality to induce graft-versus-host reaction with small bowel, pancreas\/spleen, and liver transplantation in the rat","volume":"92","author":"Kobayashi","year":"1993","journal-title":"Clinical and Experimental Immunology"},{"key":"10.1016\/j.dld.2012.08.002_bib0065","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/00007890-199507000-00009","article-title":"Variable chimerism, graft-versus-host disease, and tolerance after different kinds of cell and whole organ transplantation from Lewis to brown Norway rats","volume":"60","author":"Murase","year":"1995","journal-title":"Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0070","doi-asserted-by":"crossref","first-page":"3058","DOI":"10.1016\/j.lfs.2005.12.012","article-title":"Gender differences in ischemia\u2013reperfusion-induced microcirculatory and epithelial dysfunctions in the small intestine","volume":"78","author":"Szabo","year":"2006","journal-title":"Life Sciences"},{"key":"10.1016\/j.dld.2012.08.002_bib0075","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.bbmt.2004.04.001","article-title":"Induction of heme oxygenase-1 before conditioning results in improved survival and reduced graft-versus-host disease after experimental allogeneic bone marrow transplantation","volume":"10","author":"Gerbitz","year":"2004","journal-title":"Biology of Blood and Marrow Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0080","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1097\/01.tp.0000188948.72706.4d","article-title":"The difficulty of eliminating donor leukocyte microchimerism in rat recipients bearing established organ allografts","volume":"81","author":"Kiyomoto","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0085","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.2144\/00296st01","article-title":"The use of fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections for the study of microchimerism","volume":"29","author":"Johnson","year":"2000","journal-title":"Biotechniques"},{"key":"10.1016\/j.dld.2012.08.002_bib0090","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/0002-9610(86)90106-6","article-title":"Small bowel allografts. Sequence of histologic changes in acute and chronic rejection","volume":"151","author":"Rosemurgy","year":"1986","journal-title":"American Journal of Surgery"},{"key":"10.1016\/j.dld.2012.08.002_bib0095","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1111\/j.1432-2277.2008.00676.x","article-title":"Role of resident macrophages in the immunologic response and smooth muscle dysfunction during acute allograft rejection after intestinal transplantation","volume":"21","author":"Schaefer","year":"2008","journal-title":"Transplant International"},{"key":"10.1016\/j.dld.2012.08.002_bib0100","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/MOT.0b013e3283398fa4","article-title":"Current status of living donor small bowel transplantation","volume":"15","author":"Tzvetanov","year":"2010","journal-title":"Current Opinion in Organ Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0105","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/MOT.0b013e32835090f6","article-title":"Current progress in xenogeneic tolerance","volume":"17","author":"Yamada","year":"2012","journal-title":"Current Opinion in Organ Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0110","doi-asserted-by":"crossref","first-page":"4400","DOI":"10.1182\/blood-2011-01-328518","article-title":"Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells","volume":"117","author":"Westerhuis","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.dld.2012.08.002_bib0115","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1097\/01.TP.0000067943.90241.73","article-title":"Donor-derived hematopoietic cells in organ transplantation: a major step toward allograft tolerance","volume":"75","author":"Rifle","year":"2003","journal-title":"Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0120","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1600-065X.2011.01010.x","article-title":"Clinical tolerance in allogeneic hematopoietic stem cell transplantation","volume":"241","author":"Roncarolo","year":"2011","journal-title":"Immunological Reviews"},{"key":"10.1016\/j.dld.2012.08.002_bib0125","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.smim.2011.07.001","article-title":"Immuno-intervention for the induction of transplantation tolerance through mixed chimerism","volume":"23","author":"Sachs","year":"2011","journal-title":"Seminars in Immunology"},{"key":"10.1016\/j.dld.2012.08.002_bib0130","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1097\/00007890-199702270-00001","article-title":"Manipulation of cytokine networks in transplantation: false hope or realistic opportunity for tolerance","volume":"63","author":"Nickerson","year":"1997","journal-title":"Transplantation"},{"key":"10.1016\/j.dld.2012.08.002_bib0135","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/0952-7915(95)80069-7","article-title":"Cytokines and transplantation: Th1\/Th2 regulation of the immune response to solid organ transplants in the adult","volume":"7","author":"Dallman","year":"1995","journal-title":"Current Opinion in Immunology"},{"issue":"Suppl. 1","key":"10.1016\/j.dld.2012.08.002_bib0140","doi-asserted-by":"crossref","first-page":"S623","DOI":"10.1111\/j.1432-2277.1994.tb01458.x","article-title":"Cytokine gene expression profiles in human endomyocardial biopsy (EMB) derived lymphocyte cultures and in EMB tissue","volume":"7","author":"van Emmerik","year":"1994","journal-title":"Transplant International"},{"key":"10.1016\/j.dld.2012.08.002_bib0145","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/eji.200324550","article-title":"Interleukin 10 regulates cell surface and soluble LIR-2 (CD85d) expression on dendritic cells resulting in T cell hyporesponsiveness in vitro","volume":"34","author":"Beinhauer","year":"2004","journal-title":"European Journal of Immunology"},{"key":"10.1016\/j.dld.2012.08.002_bib0150","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.4049\/jimmunol.165.9.4848","article-title":"T regulatory cells 1 inhibit a Th2-specific response in vivo","volume":"165","author":"Cottrez","year":"2000","journal-title":"Journal of Immunology"},{"key":"10.1016\/j.dld.2012.08.002_bib0155","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1111\/j.1365-2567.2009.03057.x","article-title":"Induction of allogeneic mixed chimerism by immature dendritic cells and bone marrow transplantation leads to prolonged tolerance to major histocompatibility complex disparate allografts","volume":"127","author":"Yu","year":"2009","journal-title":"Immunology"},{"key":"10.1016\/j.dld.2012.08.002_bib0160","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1111\/j.1440-1746.2011.06783.x","article-title":"Intestinal transplantation: current status and future directions","volume":"26","author":"Garg","year":"2011","journal-title":"Journal of Gastroenterology and Hepatology"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865812002915?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865812002915?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T06:15:43Z","timestamp":1562134543000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865812002915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":32,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S1590865812002915"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2012.08.002","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}