{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:37:08Z","timestamp":1790829428525,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["dldjournalonline.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.dld.2018.11.029","type":"journal-article","created":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T14:02:36Z","timestamp":1544450556000},"page":"335-339","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Diagnostic yield of upper endoscopy according to appropriateness: A systematic review"],"prefix":"10.1016","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2329-8105","authenticated-orcid":false,"given":"Angelo","family":"Zullo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Manta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"De Francesco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Fiorini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dino","family":"Vaira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2018.11.029_bib0005","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1136\/gutjnl-2017-314109","article-title":"Quality standards in upper gastrointestinal endoscopy: a position statement of the British Society of Gastroenterology (BSG) and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland (AUGIS)","volume":"66","author":"Beg","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.dld.2018.11.029_bib0010","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.dld.2014.02.019","article-title":"White paper of Italian Gastroenterology: delivery of services for digestive diseases in Italy: weaknesses and strengths","volume":"46","author":"Buscarini","year":"2014","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2018.11.029_bib0015","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.dld.2009.04.019","article-title":"Appropriateness of the indication for upper endoscopy: a meta-analysis","volume":"42","author":"Di Giulio","year":"2010","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2018.11.029_bib0020","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.gie.2012.01.011","article-title":"ASGE standards of practice committee: appropriate use of GI endoscopy","volume":"75","author":"Early","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0025","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1055\/s-1999-71","article-title":"The European Panel on Appropriateness of Gastrointestinal Endoscopy (EPAGE): project and methods","volume":"31","author":"Vader","year":"1999","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2018.11.029_bib0030","series-title":"Methodology perspectives","first-page":"59","article-title":"The RAND\/UCLA appropriateness method","author":"Brook","year":"1994"},{"key":"10.1016\/j.dld.2018.11.029_bib0035","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1136\/gut.41.1.8","article-title":"Current European concepts in the management of Helicobacter pylori infection. The Maastricht consensus report","volume":"41","author":"The European Helicobacter pylori Study Group","year":"1997","journal-title":"Gut"},{"key":"10.1016\/j.dld.2018.11.029_bib0040","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1136\/bmj.310.6983.853","article-title":"Guidelines on appropriate indications for upper gastrointestinal endoscopy","volume":"310","author":"Axon","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.dld.2018.11.029_bib0045","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1080\/00365520802588141","article-title":"Cost-effectiveness of upper gastrointestinal endoscopy according to the appropriateness of the indication","volume":"44","author":"Di Giulio","year":"2009","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0050","series-title":"Appropriate use of gastrointestinal endoscopy","first-page":"6","author":"American Society for Gastrointestinal Endoscopy","year":"1992"},{"key":"10.1016\/j.dld.2018.11.029_bib0055","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1756-0500-5-52","article-title":"Meta-analyses and forest plots using a microsoft excel spreadsheet: step-by-step guide focusing on descriptive data analysis","volume":"5","author":"Neyeloff","year":"2012","journal-title":"BMC Res Notes"},{"key":"10.1016\/j.dld.2018.11.029_bib0060","doi-asserted-by":"crossref","first-page":"96","DOI":"10.4103\/2384-5589.170169","article-title":"Indications for an endoscopic findings in patients with symptoms of upper gastrointestinal disease in a tertiary hospital in South-Eastern Nigeria","volume":"14","author":"Picardo","year":"2015","journal-title":"Afr J Med Health Sci"},{"key":"10.1016\/j.dld.2018.11.029_bib0065","first-page":"970","article-title":"Appropriateness of indications for diagnostic upper gastrointestinal endoscopy in India","volume":"49","author":"Sumathi","year":"2008","journal-title":"Singapore Med J"},{"key":"10.1016\/j.dld.2018.11.029_bib0070","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/S0016-5107(95)70037-4","article-title":"Appropriateness of indications for diagnostic upper gastrointestinal endoscopy: association with relevant endoscopic disease","volume":"42","author":"Adang","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0075","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1136\/gut.35.9.1209","article-title":"Appropriate use of upper gastrointestinal endoscopy \u2014 a prospective audit","volume":"35","author":"Quine","year":"1994","journal-title":"Gut"},{"key":"10.1016\/j.dld.2018.11.029_bib0080","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1157\/13058395","article-title":"Idoneidad de las indicaciones de la endoscopia digestiva alta en unidades de acceso abierto","volume":"27","author":"S\u00e1nchez-del R\u00edo","year":"2004","journal-title":"Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2018.11.029_bib0085","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1001\/archinte.1996.00440170073008","article-title":"Appropriateness of referrals for open-access endoscopy. How do physicians in different medical specialties do?","volume":"156","author":"Mahajan","year":"1996","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.dld.2018.11.029_bib0090","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1046\/j.1445-2197.2002.02535.x","article-title":"Open access endoscopy in rural and remote Western Australia: does it work?","volume":"72","author":"Hughes-Anderson","year":"2002","journal-title":"ANZ J Surg"},{"key":"10.1016\/j.dld.2018.11.029_bib0095","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0016-5107(95)70036-6","article-title":"The ASGE guidelines for the appropriate use of upper gastrointestinal endoscopy in an open access system","volume":"42","author":"Minoli","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0100","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1067\/mge.2003.55","article-title":"Effectiveness of open-access endoscopy in routine primary-care practice","volume":"57","author":"Charles","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0016-5107(97)70203-7","article-title":"Does an open access system properly utilize endoscopic resources?","volume":"46","author":"Zuccaro","year":"1997","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0110","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1055\/s-2007-1005573","article-title":"Appropriateness and diagnostic yield of upper gastrointestinal endoscopy in an open-access endoscopy unit","volume":"28","author":"Gonvers","year":"1996","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2018.11.029_bib0115","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1093\/intqhc\/11.4.301","article-title":"Overuse and underuse of diagnostic upper gastrointestinal endoscopy in various clinical settings","volume":"11","author":"Seematter-Bagnoud","year":"1999","journal-title":"Int J Qual Health Care"},{"key":"10.1016\/j.dld.2018.11.029_bib0120","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0016-5107(99)70069-6","article-title":"Use of open access in GI endoscopy at an academic medical center","volume":"50","author":"Charles","year":"1999","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0125","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1067\/mge.2000.107906","article-title":"Is the diagnostic yield of upper GI endoscopy improved by the use of explicit panel-based appropriateness criteria?","volume":"52","author":"Froehlich","year":"2000","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0130","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1023\/A:1012775429096","article-title":"Appropriateness of upper gastrointestinal endoscopy. A hospital-based study","volume":"46","author":"Trevisani","year":"2001","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2018.11.029_bib0135","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1046\/j.1365-2036.2002.01136.x","article-title":"Appropriateness and diagnostic yield of upper gastrointestinal endoscopy in an open-access endoscopy system: a prospective observational study based on the Maastricht guidelines","volume":"16","author":"Manes","year":"2002","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2018.11.029_bib0140","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/S0016-5107(02)70122-3","article-title":"ASGE guidelines for the appropriate use of upper endoscopy: association with endoscopic findings","volume":"56","author":"Rossi","year":"2002","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0145","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1055\/s-2003-36407","article-title":"Open-access endoscopy: are age-based guidelines justified? An audit of experience of 1000 open-access endoscopies at a district general hospital","volume":"35","author":"Boulton-Jones","year":"2003","journal-title":"Endoscopy"},{"key":"10.1016\/j.dld.2018.11.029_bib0150","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1111\/j.1572-0241.2004.40078.x","article-title":"Comparison between the two systems to evaluate the appropriateness of endoscopy of the upper digestive tract","volume":"99","author":"Bersani","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0155","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0016-5107(04)00002-1","article-title":"Appropriateness and diagnostic yield of EGD: a prospective study in a large Asian hospital","volume":"59","author":"Chan","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0160","doi-asserted-by":"crossref","first-page":"224","DOI":"10.5144\/0256-4947.2006.224","article-title":"Appropriateness of upper gastrointestinal endoscopy referrals from primary health care","volume":"26","author":"Al-Romaih","year":"2006","journal-title":"Ann Saudi Med"},{"key":"10.1016\/j.dld.2018.11.029_bib0165","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1157\/13107917","article-title":"Guidelines for the rational use of endoscopy to improve the detection of relevant lesions in an open-access endoscopy unit: a prospective study","volume":"129","author":"Fern\u00e1ndez-Esparrach","year":"2007","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.dld.2018.11.029_bib0170","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0399-8320(06)73260-2","article-title":"Applicability and efficacy of qualifying criteria for an appropriate use of diagnostic upper gastrointestinal endoscopy","volume":"30","author":"Kaliszan","year":"2006","journal-title":"Gastroenterol Clin Biol"},{"key":"10.1016\/j.dld.2018.11.029_bib0175","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.gie.2006.12.058","article-title":"Appropriateness of upper-GI endoscopy: an Italian survey on behalf of the Italian Society of Digestive Endoscopy","volume":"65","author":"Hassan","year":"2007","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0180","first-page":"427","article-title":"Indications for upper gastrointestinal endoscopy: the accuracy of the American Society for Gastrointestinal Endoscopy Guidelines in a Portuguese hospital","volume":"21","author":"Cerqueira","year":"2008","journal-title":"Acta Med Port"},{"key":"10.1016\/j.dld.2018.11.029_bib0185","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1038\/ajg.2009.675","article-title":"Appropriateness guidelines and predictive rules to select patients for upper endoscopy: a nationwide multicenter study","volume":"105","author":"Buri","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0190","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1155\/2011\/379014","article-title":"A nine-year audit of open-access upper gastrointestinal endoscopic procedures: results and experience of a single centre","volume":"25","author":"Keren","year":"2011","journal-title":"Can J Gastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0195","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4253\/wjge.v3.i10.195","article-title":"Appropriateness of outpatient gastrointestinal endoscopy in a non-academic hospital","volume":"3","author":"Mangualde","year":"2011","journal-title":"World J Gastrointest Endosc"},{"key":"10.1016\/j.dld.2018.11.029_bib0200","first-page":"158","article-title":"Appropriateness and diagnostic yield of referrals for oesophagogastroduodenoscopy at the Korle Bu Teaching Hospital","volume":"30","author":"Tachi","year":"2011","journal-title":"West Afr J Med"},{"key":"10.1016\/j.dld.2018.11.029_bib0205","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ajg.2012.08.009","article-title":"Appropriate use and diagnostic yield of upper gastrointestinal endoscopy in a tertiary referral hospital","volume":"13","author":"Mudawi","year":"2012","journal-title":"Arab J Gastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0210","first-page":"507","article-title":"Appropriateness of indication for upper gastrointestinal endoscopy in a Tunisian endoscopy unit","volume":"93","author":"Ennaifer","year":"2015","journal-title":"Tunis Med"},{"key":"10.1016\/j.dld.2018.11.029_bib0215","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/1319-3767.118128","article-title":"Appropriateness and diagnostic yield of upper gastrointestinal endoscopy in an open-access endoscopy system","volume":"19","author":"Aljebreen","year":"2013","journal-title":"Saudi J Gastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0220","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5005\/jp-journals-10018-1187","article-title":"Appropriateness of upper gastrointestinal endoscopy: will the diagnostic yield improve by the use of American Society of Gastroenterology Guidelines?","volume":"6","author":"Tahir","year":"2016","journal-title":"Euroasian J Hepatogastroenterol"},{"key":"10.1016\/j.dld.2018.11.029_bib0225","unstructured":"NICE Clinical guideline. Metastatic malignant disease of unknown primary origin in adults: diagnosis and management. Published: 26 July 2010; nice.org.uk\/guidance\/cg104."},{"key":"10.1016\/j.dld.2018.11.029_bib0230","unstructured":"Position Statement produced by BSG, AUGIS and ACPGBI. Guidance on the indications for diagnostic upper GI endoscopy, flexible sigmoidoscopy and colonoscopy. https:\/\/www.bsg.org.uk\/resource\/indications_diagnostic_endoscopy_13-pdf.html."},{"issue":"September","key":"10.1016\/j.dld.2018.11.029_bib0235","article-title":"Future development of gastrointestinal cancer incidence and mortality rates in Switzerland: a tumour registry- and population-based projection up to 2030","volume":"145","author":"Joliat","year":"2015","journal-title":"Swiss Med Wkly"},{"issue":"1","key":"10.1016\/j.dld.2018.11.029_bib0240","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1186\/s12916-016-0718-z","article-title":"Effective and safe proton pump inhibitor therapy in acid-related diseases \u2014 a position paper addressing benefits and potential harms of acid suppression","volume":"14","author":"Scarpignato","year":"2016","journal-title":"BMC Med"},{"key":"10.1016\/j.dld.2018.11.029_bib0245","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.ejim.2014.08.010","article-title":"Prevalence of lesions detected at upper endoscopy: an Italian survey","volume":"25","author":"Zullo","year":"2014","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.dld.2018.11.029_bib0250","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/hel.12149","article-title":"Detection of gastric precancerous conditions in daily clinical practice: a nationwide survey","volume":"19","author":"Lahner","year":"2014","journal-title":"Helicobacter"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865818312684?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865818312684?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T21:04:51Z","timestamp":1551301491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865818312684"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S1590865818312684"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2018.11.029","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic yield of upper endoscopy according to appropriateness: A systematic review","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2018.11.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}