{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T17:39:35Z","timestamp":1773941975407,"version":"3.50.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.dld.2020.07.035","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T03:24:14Z","timestamp":1598671454000},"page":"442-444","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Early hydrogen excretion peaks during breath tests. Small intestinal bacterial overgrowth or accelerated transit?"],"prefix":"10.1016","volume":"53","author":[{"given":"Piero","family":"Vernia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Cesarini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"de Carolis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Vernia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2020.07.035_bib0001","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00535-018-1476-9","article-title":"Prevalence and predictors of small intestinal bacterial overgrowth in irritable bowel syndrome: a systematic review and metanalysis","volume":"53","author":"Chen","year":"2018","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.dld.2020.07.035_bib0002","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11894-019-0671-z","article-title":"The Spectrum of Small Intestinal Bacterial Overgrowth (SIBO)","volume":"21","author":"Quigley","year":"2019","journal-title":"Curr Gastroenterol Rep"},{"issue":"11","key":"10.1016\/j.dld.2020.07.035_bib0003","doi-asserted-by":"crossref","first-page":"e13494","DOI":"10.1111\/nmo.13494","article-title":"The diagnosis of small intestinal bacterial overgrowth: Two steps forward, one step backwards?","volume":"30","author":"Di Stefano","year":"2018","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.dld.2020.07.035_bib0004","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/gut.2005.075127","article-title":"Use and abuse of hydrogen breath tests","volume":"55","author":"Simren","year":"2006","journal-title":"Gut"},{"key":"10.1016\/j.dld.2020.07.035_bib0005","article-title":"Diagnostic Utility of Carbohydrate Breath Tests for SIBO, Fructose, and Lactose Intolerance","author":"Amieva-Balmori","year":"2019","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2020.07.035_bib0006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2036.2009.03951.x","article-title":"Methodology and indications of H2-breath testing in gastrointestinal diseases: the Rome Consensus Conference","volume":"29","author":"Gasbarrini","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2020.07.035_bib0007","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/ajg.2017.46","article-title":"Hydrogen and methane-based breath testing in gastrointestinal disorders: the North American Consensus","volume":"112","author":"Rezaie","year":"2017","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2020.07.035_bib0008","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/nmo.12516","article-title":"Small intestinal bacterial overgrowth: duodenal aspiration vs glucose breath test","volume":"27","author":"Erdogan","year":"2015","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.dld.2020.07.035_bib0009","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1136\/gut.2009.205476","article-title":"Combined oro-caecal scintigraphy and lactulose hydrogen breath testing demonstrate that breath testing detects oro-caecal transit, not small intestinal bacterial overgrowth in patients with IBS","volume":"60","author":"Yu","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.dld.2020.07.035_bib0010","doi-asserted-by":"crossref","first-page":"e13350","DOI":"10.1111\/nmo.13350","article-title":"Does a glucose- based hydrogen and methane breath test detect bacterial overgrowth in the jejunum?","volume":"30","author":"Sundin","year":"2018","journal-title":"Neurogastroenterol Motil."},{"key":"10.1016\/j.dld.2020.07.035_bib0011","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/ajcn\/39.1.100","article-title":"Prevalence of primary adult lactose malabsorption and awareness of milk intolerance in Italy","volume":"39","author":"Burgio","year":"1984","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.dld.2020.07.035_bib0012","doi-asserted-by":"crossref","first-page":"6204","DOI":"10.3748\/wjg.14.6204","article-title":"Hydrogen breath test for the diagnosis of lactose intolerance, is the routine sugar load the best one?","volume":"14","author":"Argnani","year":"2008","journal-title":"World J Gastroenterol."},{"issue":"5","key":"10.1016\/j.dld.2020.07.035_bib0013","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0230784","article-title":"The role of small intestinal bacterial overgrowth and false positive diagnosis of lactose intolerance in southwest Hungary\u2014A retrospective observational study","volume":"15","author":"Varj\u00f9","year":"2020","journal-title":"Plos One"},{"key":"10.1016\/j.dld.2020.07.035_bib0014","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1111\/jgh.12862","article-title":"Small intestinal bacterial overgrowth as an uncommon cause of false positive lactose hydrogen breath test among patients with diarrhea-predominant irritable bowel syndrome in Asia","volume":"30","author":"Wang","year":"2015","journal-title":"J Gastroenterol Hepatol"},{"issue":"suppl 1.","key":"10.1016\/j.dld.2020.07.035_bib0015","first-page":"18","article-title":"H2 breath testing for small intestinal bacterial overgrowth","volume":"29","author":"Parodi","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2020.07.035_bib0016","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.cgh.2015.07.032","article-title":"Scintigraphy demonstrates high rate of false-positive results from glucose breath tests for small bowel bacterial overgrowth","volume":"14","author":"Lin","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2020.07.035_bib0017","first-page":"1795","article-title":"The lactulose breath hydrogen test and small intestinal bacterial overgrowth","volume":"91","author":"Riordan","year":"1996","journal-title":"AM J Gastroenterol"},{"key":"10.1016\/j.dld.2020.07.035_bib0018","article-title":"Diagnosing small intestinal bacterial overgrowth: a comparison of lactulose breath tests to small bowel aspirates","author":"Cangemi","year":"2020","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2020.07.035_bib0019","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1111\/j.1572-0241.2000.03368.x","article-title":"Eradication of small intestinal bacterial overgrowth correlates with symptom improvement in irritable bowel syndrome: a double blind, randomized controlled study","volume":"95","author":"Pimentel","year":"2000","journal-title":"Am J Gastroenterol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865820303960?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865820303960?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:15:08Z","timestamp":1761624908000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865820303960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S1590865820303960"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2020.07.035","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early hydrogen excretion peaks during breath tests. Small intestinal bacterial overgrowth or accelerated transit?","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2020.07.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}