{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:23:59Z","timestamp":1761625439573,"version":"build-2065373602"},"reference-count":13,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T00:00:00Z","timestamp":1627776000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1016\/j.dld.2021.04.027","type":"journal-article","created":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T16:49:17Z","timestamp":1621183757000},"page":"1065-1067","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Does chronic consumption of angiotensin-converting enzyme inhibitors affect survival after surgical resection of pancreatic ductal adenocarcinoma?"],"prefix":"10.1016","volume":"53","author":[{"given":"Domenico","family":"Tamburrino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Guarneri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Partelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Crippa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Falconi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Capurso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2021.04.027_bib0001","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.dld.2021.04.027_bib0002","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/ije\/dyx269","article-title":"Risk of pancreatic cancer associated with family history of cancer and other medical conditions by accounting for smoking among relatives","volume":"47","author":"Molina-Montes","year":"2018","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.dld.2021.04.027_bib0003","doi-asserted-by":"crossref","first-page":"7706","DOI":"10.1111\/jcmm.15413","article-title":"The Impact of obesity and diabetes mellitus on pancreatic cancer: molecular mechanisms and clinical perspectives","volume":"24","author":"Quoc Lam","year":"2020","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.dld.2021.04.027_bib0004","doi-asserted-by":"crossref","first-page":"13024","DOI":"10.1038\/s41598-017-13430-z","article-title":"Exclusive and combined use of statins and aspirin and the risk of pancreatic cancer: a case-control study","volume":"7","author":"Archibugi","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.dld.2021.04.027_bib0005","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.dld.2020.01.008","article-title":"Statin use improves survival in patients with pancreatic ductal adenocarcinoma: a meta-analysis","volume":"52","author":"Tamburrino","year":"2020","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2021.04.027_bib0006","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1038\/sj.bjc.6605955","article-title":"Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine","volume":"103","author":"Nakai","year":"2010","journal-title":"Br J Cancer"},{"key":"10.1016\/j.dld.2021.04.027_bib0007","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2174\/187152506777698326","article-title":"Blockade of the renin-angiotensin-aldosterone system: effects on hypertensive target organ damage","volume":"4","author":"Grandi","year":"2008","journal-title":"Cardiovasc Hematol Agents Med Chem"},{"key":"10.1016\/j.dld.2021.04.027_bib0008","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1097\/CEJ.0000000000000269","article-title":"The effect of angiotensin system inhibitors (Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers) on cancer recurrence and survival: a meta-analysis","volume":"26","author":"Song","year":"2017","journal-title":"Eur J Cancer Prev"},{"issue":"9","key":"10.1016\/j.dld.2021.04.027_bib0009","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1007\/s00268-017-4021-8","article-title":"Impact of angiotensin receptor blocker use on overall survival among patients undergoing resection for pancreatic cancer","volume":"41","author":"Cerullo","year":"2017","journal-title":"World J Surg"},{"issue":"19","key":"10.1016\/j.dld.2021.04.027_bib0010","doi-asserted-by":"crossref","first-page":"5959","DOI":"10.1158\/1078-0432.CCR-17-0256","article-title":"Use of angiotensin system inhibitors is associated with immune activation and longer survival in nonmetastatic pancreatic ductal adenocarcinoma","volume":"23","author":"Liu","year":"2017","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.dld.2021.04.027_bib0011","first-page":"e13219","article-title":"Prognostic impact of charlson's age-comorbidity index and other risk factors in patients with pancreatic cancer","volume":"29","author":"Bagni","year":"2020","journal-title":"Eur J Cancer Care (Engl)"},{"key":"10.1016\/j.dld.2021.04.027_bib0012","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1158\/1535-7163.MCT-19-0228","article-title":"Antiproliferative effects of monoclonal antibodies against (Pro) renin receptor in pancreatic ductal adenocarcinoma","volume":"19","author":"Rahman","year":"2020","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.dld.2021.04.027_bib0013","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1093\/carcin\/bgn171","article-title":"The renin-angiotensin system and malignancy","volume":"29","author":"Ager","year":"2008","journal-title":"Carcinogenesis"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821002127?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821002127?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:16:17Z","timestamp":1761624977000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865821002127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":13,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S1590865821002127"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2021.04.027","relation":{},"ISSN":["1590-8658"],"issn-type":[{"type":"print","value":"1590-8658"}],"subject":[],"published":{"date-parts":[[2021,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does chronic consumption of angiotensin-converting enzyme inhibitors affect survival after surgical resection of pancreatic ductal adenocarcinoma?","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2021.04.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}