{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:55:48Z","timestamp":1789052148547,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.dld.2021.06.026","type":"journal-article","created":{"date-parts":[[2021,7,14]],"date-time":"2021-07-14T09:24:00Z","timestamp":1626254640000},"page":"336-342","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Antitissue transglutaminase antibodies\u2019 normalization after starting a gluten-free diet in a large population of celiac children-a real-life experience"],"prefix":"10.1016","volume":"54","author":[{"given":"Francesca","family":"Sbravati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Cosentino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Lenzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelangelo","family":"Fiorentino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Ambrosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Salerno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annarita","family":"Di Biase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Righi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Brusa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola Sogno","family":"Valin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Bruni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Battistini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Pagano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Gabriela","family":"Grondona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Labriola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Alvisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2021.06.026_bib0001","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/MPG.0b013e31821a23d0","article-title":"European society for pediatric gastroenterology, hepatology, and nutrition guidelines for the diagnosis of coeliac disease","volume":"54","author":"Husby","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0002","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/MPG.0000000000002497","article-title":"European society paediatric gastroenterology, hepatology and nutrition guidelines for diagnosing coeliac disease 2020","volume":"70","author":"Husby","year":"2020","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.1536-4801.2005.tb00917.x","article-title":"Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the north american society for pediatric gastroenterology, hepatology and nutrition","volume":"40","author":"Hill","year":"2005","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0004","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1038\/ajg.2014.200","article-title":"Can celiac serology alone be used as a marker of duodenal mucosal recovery in children with celiac disease on a gluten-free diet?","volume":"109","author":"Bannister","year":"2014","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2021.06.026_bib0005","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1111\/j.1365-2036.2008.03820.x","article-title":"Systematic review: the evidence base for long-term management of coeliac disease","volume":"28","author":"Haines","year":"2008","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2021.06.026_bib0006","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1136\/adc.65.8.909","article-title":"Report of working group of european society of paediatric gastroenterology and nutrition","volume":"65","year":"1990","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.dld.2021.06.026_bib0007","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/0016-5085(92)91819-P","article-title":"Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue\u2019)","volume":"102","author":"Marsh","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2021.06.026_bib0008","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1097\/00042737-199910000-00019","article-title":"The histopathology of coeliac disease: time for a standardized report scheme for pathologists","volume":"11","author":"Oberhuber","year":"1999","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.06.026_bib0009","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/MPG.0000000000002519","article-title":"Trend of antitissue transglutaminase antibody normalization in children with celiac disease started on gluten-free diet: a comparative study between chemiluminescence and ELISA serum assays","volume":"70","author":"Sansotta","year":"2020","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0010","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/MPG.0b013e318232c459","article-title":"Monitoring of anti-transglutaminase autoantibodies in pediatric celiac disease using a sensitive radiobinding assay","volume":"54","author":"Candon","year":"2012","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"6","key":"10.1016\/j.dld.2021.06.026_bib0011","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1515\/CCLM.2011.164","article-title":"Use of a fully automated immunoassay for celiac disease screening in a pediatric population","volume":"49","author":"Ress","year":"2011","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.dld.2021.06.026_bib0012","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1017\/S0007114509301579","article-title":"A gluten-free diet score to evaluate dietary compliance in patients with coeliac disease","volume":"102","author":"Biagi","year":"2009","journal-title":"Br J Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0013","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1017\/S0007114511007367","article-title":"A score that verifies adherence to a gluten-free diet: a cross-sectional, multicentre validation in real clinical life","volume":"108","author":"Biagi","year":"2012","journal-title":"Br J Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0014","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1002\/sim.4067","article-title":"Multiple imputation using chained equations: issues and guidance for practice","volume":"30","author":"White","year":"2011","journal-title":"Stat Med"},{"issue":"3","key":"10.1016\/j.dld.2021.06.026_bib0015","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1093\/biomet\/81.3.515","article-title":"Proportional hazards tests and diagnostics based on weighted residuals","volume":"81","author":"Grambsch","year":"1994","journal-title":"Biometrika"},{"key":"10.1016\/j.dld.2021.06.026_bib0016","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/ajg.2013.79","article-title":"ACG clinical guidelines: diagnosis and management of celiac disease","volume":"108","author":"Rubio-Tapia","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2021.06.026_bib0017","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/MPG.0000000000001270","article-title":"Normalization time of celiac serology in children on a gluten-free diet","volume":"64","author":"Gidrewicz","year":"2017","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0018","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/MPG.0000000000001480","article-title":"Antitissue transglutaminase normalization postdiagnosis in children with celiac disease","volume":"65","author":"Isaac","year":"2017","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"3","key":"10.1016\/j.dld.2021.06.026_bib0019","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1542\/peds.2010-3762","article-title":"Specific celiac disease antibodies in children on a gluten-free diet","volume":"128","author":"Hogen Esch","year":"2011","journal-title":"Pediatrics"},{"key":"10.1016\/j.dld.2021.06.026_bib0020","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1155\/2014\/629209","article-title":"Exploring anthropometric and laboratory differences in children of varying ethnicities with celiac disease","volume":"28","author":"Rajani","year":"2014","journal-title":"Can J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.06.026_bib0021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu10101424","article-title":"Adherence to gluten-free diet in children with celiac disease","volume":"10","author":"Czaja-Bulsa","year":"2018","journal-title":"Nutrients"},{"key":"10.1016\/j.dld.2021.06.026_bib0022","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1097\/MPG.0000000000002676","article-title":"Adherence to gluten-free diet in a celiac pediatric population referred to the general pediatrician after remission","volume":"71","author":"Sbravati","year":"2020","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0023","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/ejcn.2013.54","article-title":"Determinants of adherence to gluten-free diet in Greek children with coeliac disease: a cross-sectional study","volume":"67","author":"Charalampopoulos","year":"2013","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.dld.2021.06.026_bib0024","doi-asserted-by":"crossref","first-page":"72","DOI":"10.4274\/jcrpe.galenos.2020.2020.0108","article-title":"Frequency of celiac disease and spontaneous normalization rate of celiac serology in children and adolescent patients with type 1 diabetes","volume":"13","author":"Unal","year":"2020","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"10.1016\/j.dld.2021.06.026_bib0025","doi-asserted-by":"crossref","first-page":"760","DOI":"10.2337\/dc14-2890","article-title":"High rate of spontaneous normalization of celiac serology in a cohort of 446 children with type 1 diabetes: a prospective study","volume":"38","author":"Castellaneta","year":"2015","journal-title":"Diabetes Care"},{"key":"10.1016\/j.dld.2021.06.026_bib0026","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1007\/s10620-011-2016-0","article-title":"Spontaneous normalization of anti-tissue transglutaminase antibody levels is common in children with type 1 diabetes mellitus","volume":"57","author":"Waisbourd-Zinman","year":"2012","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.dld.2021.06.026_bib0027","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1111\/j.1572-0241.2007.01360.x","article-title":"Fate of five celiac disease-associated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study","volume":"102","author":"Simell","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2021.06.026_bib0028","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00431-020-03770-w","article-title":"Anti-tissue transglutaminase titers are associated with endoscopic findings and severity of mucosal damage in children with celiac disease","volume":"180","author":"Ziv-Baran","year":"2021","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.dld.2021.06.026_bib0029","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/MCG.0b013e31802e70b1","article-title":"Strongly positive tissue transglutaminase antibodies are associated with marsh 3 histopathology in adult and pediatric celiac disease","volume":"42","author":"Donaldson","year":"2008","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.dld.2021.06.026_bib0030","series-title":"A clinical guide to gluten-related disorders","author":"Fasano","year":"2014"},{"key":"10.1016\/j.dld.2021.06.026_bib0031","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/MPG.0000000000000390","article-title":"Mucosal healing in children with treated celiac disease","volume":"59","author":"Ghazzawi","year":"2014","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"1","key":"10.1016\/j.dld.2021.06.026_bib0032","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-230X-14-28","article-title":"Follow-up of pediatric celiac disease: value of antibodies in predicting mucosal healing, a prospective cohort study","volume":"14","author":"V\u00e9csei","year":"2014","journal-title":"BMC Gastroenterol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821003406?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821003406?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:19:23Z","timestamp":1761625163000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865821003406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S1590865821003406"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2021.06.026","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antitissue transglutaminase antibodies\u2019 normalization after starting a gluten-free diet in a large population of celiac children-a real-life experience","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2021.06.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}