{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T02:55:31Z","timestamp":1783652131487,"version":"3.55.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010109","name":"Medizinische Universit\u00e4t Graz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010109","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007054","name":"Meso Scale Diagnostics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008349","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","dldjournalonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Digestive and Liver Disease"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1016\/j.dld.2021.09.009","type":"journal-article","created":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T03:03:46Z","timestamp":1637031826000},"page":"500-508","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["The prognostic value of HVPG-response to non-selective beta-blockers in patients with NASH cirrhosis and varices"],"prefix":"10.1016","volume":"54","author":[{"given":"Rafael","family":"Paternostro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeannette","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt Silvester","family":"Hofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Panagl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Schiffke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt","family":"Simbrunner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Semmler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philipp","family":"Schwabl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Scheiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Bucsics","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Binter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Trauner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattias","family":"Mandorfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4590-3583","authenticated-orcid":false,"given":"Thomas","family":"Reiberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.dld.2021.09.009_bib0001","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.jhep.2018.05.011","article-title":"Burden of liver disease in Europe: epidemiology and analysis of risk factors to identify prevention policies","volume":"69","author":"Pimpin","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0002","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nrgastro.2017.109","article-title":"Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention","volume":"15","author":"Younossi","year":"2018","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0003","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1053\/j.gastro.2017.01.003","article-title":"Changes in the prevalence of hepatitis C virus infection, nonalcoholic steatohepatitis, and alcoholic liver disease among patients with cirrhosis or liver failure on the waitlist for liver transplantation","volume":"152","author":"Goldberg","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2021.09.009_bib0004","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1002\/hep.29085","article-title":"Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: systematic review and meta-analysis","volume":"65","author":"Dulai","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0005","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/hep.28906","article-title":"Portal hypertensive bleeding in cirrhosis: risk stratification, diagnosis, and management: 2016 practice guidance by the American association for the study of liver diseases","volume":"65","author":"Garcia-Tsao","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0006","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00508-017-1262-3","article-title":"Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III)","volume":"129","author":"Reiberger","year":"2017","journal-title":"Wien Klin Wochenschr"},{"key":"10.1016\/j.dld.2021.09.009_bib0007","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jhep.2017.10.020","article-title":"Clinical states of cirrhosis and competing risks","volume":"68","author":"D'Amico","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0008","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1056\/NEJMoa044456","article-title":"Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis","volume":"353","author":"Groszmann","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.dld.2021.09.009_bib0009","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/S0140-6736(03)12778-X","article-title":"Prevention of variceal rebleeding","volume":"361","author":"Bosch","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2021.09.009_bib0010","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1053\/jhep.2000.19322","article-title":"The hemodynamic response to medical treatment of portal hypertension as a predictor of clinical effectiveness in the primary prophylaxis of variceal bleeding in cirrhosis","volume":"32","author":"Merkel","year":"2000","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0011","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jhep.2007.10.008","article-title":"Hepatic venous pressure gradient and prognosis in patients with acute variceal bleeding treated with pharmacologic and endoscopic therapy","volume":"48","author":"Abraldes","year":"2008","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0012","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S0016-5085(99)70455-5","article-title":"Prognostic value of early measurements of portal pressure in acute variceal bleeding","volume":"117","author":"Moitinho","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2021.09.009_bib0013","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1136\/gutjnl-2012-304038","article-title":"Carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol","volume":"62","author":"Reiberger","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.dld.2021.09.009_bib0014","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/apt.14485","article-title":"Betablockers do not increase efficacy of band ligation in primary prophylaxis but they improve survival in secondary prophylaxis of variceal bleeding","volume":"47","author":"Pfisterer","year":"2018","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.dld.2021.09.009_bib0015","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1002\/hep.30220","article-title":"Comparison of therapies for primary prevention of esophageal variceal bleeding: a systematic review and network meta-analysis","volume":"69","author":"Sharma","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0016","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1016\/S0140-6736(18)31875-0","article-title":"beta blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial","volume":"393","author":"Villanueva","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.dld.2021.09.009_bib0017","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1053\/j.gastro.2014.03.005","article-title":"Nonselective beta blockers increase risk for hepatorenal syndrome and death in patients with cirrhosis and spontaneous bacterial peritonitis","volume":"146","author":"Mandorfer","year":"2014","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.dld.2021.09.009_bib0018","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.dld.2016.09.013","article-title":"Beta blockers and cirrhosis, 2016","volume":"49","author":"Mandorfer","year":"2017","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.dld.2021.09.009_bib0019","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s11901-019-00469-x","article-title":"Hepatic venous pressure gradient response in non-selective beta-blocker treatment\u2014is it worth measuring?","volume":"18","author":"Mandorfer","year":"2019","journal-title":"Curr Hepatol Rep"},{"key":"10.1016\/j.dld.2021.09.009_bib0020","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.jhep.2015.05.022","article-title":"Expanding consensus in portal hypertension: report of the Baveno VI Consensus Workshop: stratifying risk and individualizing care for portal hypertension","volume":"63","author":"de Franchis","year":"2015","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0021","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1002\/hep.30664","article-title":"The natural history of advanced fibrosis due to nonalcoholic steatohepatitis: data from the simtuzumab trials","volume":"70","author":"Sanyal","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0022","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/MEG.0000000000000825","article-title":"Stage of fibrosis and portal pressure correlation in nonalcoholic steatohepatitis","volume":"29","author":"Sourianarayanane","year":"2017","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0023","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1111\/apt.14576","article-title":"Carvedilol for reducing portal pressure in primary prophylaxis of variceal bleeding: a dose-response study","volume":"47","author":"Schwarzer","year":"2018","journal-title":"Aliment Pharmacol Ther"},{"issue":"160","key":"10.1016\/j.dld.2021.09.009_bib0024","doi-asserted-by":"crossref","DOI":"10.3791\/58819","article-title":"Measurement of the hepatic venous pressure gradient and transjugular liver biopsy","volume":"18","author":"Reiberger","year":"2020","journal-title":"J Vis Exp"},{"key":"10.1016\/j.dld.2021.09.009_bib0025","doi-asserted-by":"crossref","DOI":"10.1111\/liv.12783","article-title":"Evaluation of a new balloon occlusion catheter specifically designed for measurement of hepatic venous pressure gradient","author":"Ferlitsch","year":"2015","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2021.09.009_bib0026","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1002\/hep.1840360612","article-title":"Randomized comparison of long-term carvedilol and propranolol administration in the treatment of portal hypertension in cirrhosis","volume":"36","author":"Banares","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0027","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1038\/ajg.2016.327","article-title":"A randomized, multi-center, open-label study to evaluate the efficacy of carvedilol vs. propranolol to reduce portal pressure in patients with liver cirrhosis","volume":"111","author":"Kim","year":"2016","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.dld.2021.09.009_bib0028","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/hep.510300124","article-title":"Carvedilol, a new nonselective beta-blocker with intrinsic anti- alpha1-adrenergic activity, has a greater portal hypotensive effect than propranolol in patients with cirrhosis","volume":"30","author":"Banares","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0029","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jhep.2017.09.021","article-title":"Hypertension, diabetes, atherosclerosis and NASH: cause or consequence?","volume":"68","author":"Lonardo","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0030","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jhep.2018.02.032","article-title":"Development of a scoring system to predict hepatocellular carcinoma in Asians on antivirals for chronic hepatitis B","volume":"69","author":"Hsu","year":"2018","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0031","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/hep.27212","article-title":"Increased risk of cirrhosis and its decompensation in chronic hepatitis C patients with new-onset diabetes: a nationwide cohort study","volume":"60","author":"Huang","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0032","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/hep.27228","article-title":"Diabetes mellitus is an independent prognostic factor for major liver-related outcomes in patients with cirrhosis and chronic hepatitis C","volume":"60","author":"Elkrief","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0033","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/s41424-018-0053-0","article-title":"Association between type 2 diabetes mellitus, HbA1c and the risk for spontaneous bacterial peritonitis in patients with decompensated liver cirrhosis and ascites","volume":"9","author":"Tergast","year":"2018","journal-title":"Clin Transl Gastroenterol"},{"key":"10.1016\/j.dld.2021.09.009_bib0034","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.cgh.2017.12.009","article-title":"Effects of diabetes and glycemic control on risk of hepatocellular carcinoma after seroclearance of hepatitis B surface antigen","volume":"16","author":"Cheuk-Fung Yip","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0035","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/S0016-5085(97)70142-2","article-title":"Effects of ethanol consumption on hepatic hemodynamics in patients with alcoholic cirrhosis","volume":"112","author":"Luca","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2021.09.009_bib0036","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/liv.12559","article-title":"Systemic inflammation is associated with increased intrahepatic resistance and mortality in alcohol-related acute-on-chronic liver failure","volume":"35","author":"Mehta","year":"2015","journal-title":"Liver Int"},{"key":"10.1016\/j.dld.2021.09.009_bib0037","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.jhep.2016.05.027","article-title":"Sustained virologic response to interferon-free therapies ameliorates HCV-induced portal hypertension","volume":"65","author":"Mandorfer","year":"2016","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0038","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1002\/hep.30885","article-title":"Changes in hepatic venous pressure gradient predict hepatic decompensation in patients who achieved sustained virologic response to interferon-free therapy","volume":"71","author":"Mandorfer","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0039","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1053\/j.gastro.2018.04.034","article-title":"Fibrosis severity as a determinant of cause-specific mortality in patients with advanced nonalcoholic fatty liver disease: a multi-national cohort Study","volume":"155","author":"Vilar-Gomez","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2021.09.009_bib0040","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1136\/gutjnl-2011-301348","article-title":"The window hypothesis: haemodynamic and non-haemodynamic effects of \u03b2-blockers improve survival of patients with cirrhosis during a window in the disease","volume":"61","author":"Krag","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.dld.2021.09.009_bib0041","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.jhep.2016.11.001","article-title":"Beta adrenergic blockade and decompensated cirrhosis","volume":"66","author":"Reiberger","year":"2017","journal-title":"J Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0042","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/hep.23775","article-title":"Deleterious effects of beta-blockers on survival in patients with cirrhosis and refractory ascites","volume":"52","author":"Serst\u00e9","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0043","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0128774","article-title":"Prognostic value of non-invasive fibrosis and steatosis tools, hepatic venous pressure gradient (HVPG) and Histology in nonalcoholic steatohepatitis","volume":"10","author":"Sebastiani","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.dld.2021.09.009_bib0044","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1053\/j.gastro.2018.07.006","article-title":"Simtuzumab is ineffective for patients with bridging fibrosis or compensated cirrhosis caused by nonalcoholic steatohepatitis","volume":"155","author":"Harrison","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.dld.2021.09.009_bib0045","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cgh.2019.05.050","article-title":"Lowering portal pressure improves outcomes of patients with cirrhosis, with or without ascites: a meta-analysis","volume":"18","author":"Turco","year":"2020","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.dld.2021.09.009_bib0046","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s11901-018-0420-z","article-title":"Small esophageal varices in patients with cirrhosis-should we treat them?","volume":"17","author":"Reiberger","year":"2018","journal-title":"Curr Hepatol Rep"},{"key":"10.1016\/j.dld.2021.09.009_bib0047","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/hep.28264","article-title":"Development of hyperdynamic circulation and response to \u03b2-blockers in compensated cirrhosis with portal hypertension","volume":"63","author":"Villanueva","year":"2016","journal-title":"Hepatology"},{"key":"10.1016\/j.dld.2021.09.009_bib0048","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.jhep.2020.05.011","article-title":"Non-selective beta-blockers impair global circulatory homeostasis and renal function in cirrhotic patients with refractory ascites","volume":"73","author":"T\u00e9llez","year":"2020","journal-title":"J Hepatol"}],"container-title":["Digestive and Liver Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821007787?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1590865821007787?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:18:29Z","timestamp":1761625109000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1590865821007787"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S1590865821007787"],"URL":"https:\/\/doi.org\/10.1016\/j.dld.2021.09.009","relation":{},"ISSN":["1590-8658"],"issn-type":[{"value":"1590-8658","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The prognostic value of HVPG-response to non-selective beta-blockers in patients with NASH cirrhosis and varices","name":"articletitle","label":"Article Title"},{"value":"Digestive and Liver Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.dld.2021.09.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd on behalf of Editrice Gastroenterologica Italiana S.r.l.","name":"copyright","label":"Copyright"}]}}